Citations (47)
Keep up to date with the latest research on this topic with citation updates for this article.
Articles from other publishers (47)
Xuezhang Tian, Yaru Zhou, Shaowei Wang, Ming Gao, Yanlin Xia, Yangyang Li, Yunhong Zhong, Wenhao Xu, Lei Bai, Bishi Fu, Yu Zhou, Hye-Ra Lee, Hongyu Deng, Ke Lan, Pinghui Feng & Junjie Zhang. (2023) Genome-Wide CRISPR-Cas9 Screen Identifies SMCHD1 as a Restriction Factor for Herpesviruses. mBio 14:2.
Crossref
Crossref
Massimo Carraro, Ivo A. Hendriks, Colin M. Hammond, Victor Solis-Mezarino, Moritz Völker-Albert, Jonas D. Elsborg, Melanie B. Weisser, Christos Spanos, Guillermo Montoya, Juri Rappsilber, Axel Imhof, Michael L. Nielsen & Anja Groth. (2023) DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network. Molecular Cell 83:7, pages 1075-1092.e9.
Crossref
Crossref
Kaoru Inoue, Hamed Bostan, MaKenna R. Browne, Owen F. BevisCarl D. Bortner, Steven A. MooreAaron A. StenceNegin P. Martin, Shih-Heng ChenAdam B. BurkholderJian-Liang Li & Natalie D. Shaw. (2023) DUX4 double whammy: The transcription factor that causes a rare muscular dystrophy also kills the precursors of the human nose. Science Advances 9:7.
Crossref
Crossref
Mara S. Tihaya, Karlien Mul, Judit Balog, Jessica C. de Greef, Stephen J. Tapscott, Rabi Tawil, Jeffrey M. Statland & Silvère M. van der Maarel. (2023) Facioscapulohumeral muscular dystrophy: the road to targeted therapies. Nature Reviews Neurology 19:2, pages 91-108.
Crossref
Crossref
Alexander I. Shevchenko, Nikita A. Rifel, Suren M. Zakian & Irina S. Zakharova. (2022) Constitutive heterochromatin propagation contributes to the X chromosome inactivation. Chromosome Research 30:4, pages 289-307.
Crossref
Crossref
Pauline Robbe, Kate E. Ridout, Dimitrios V. Vavoulis, Helene Dréau, Ben Kinnersley, Nicholas Denny, Daniel Chubb, Niamh Appleby, Anthony Cutts, Alex J. Cornish, Laura Lopez-Pascua, Ruth Clifford, Adam Burns, Basile Stamatopoulos, Maite Cabes, Reem Alsolami, Pavlos Antoniou, Melanie Oates, Doriane Cavalieri, J. C. Ambrose, P. Arumugam, R. Bevers, M. Bleda, F. Boardman-Pretty, C. R. Boustred, H. Brittain, M. A. Brown, Marc J. Caulfield, G. C. Chan, T. Fowler, A. Giess, A. Hamblin, S. Henderson, T. J. P. Hubbard, R. Jackson, L. J. Jones, D. Kasperaviciute, M. Kayikci, A. Kousathanas, L. Lahnstein, S. E. A. Leigh, I. U. S. Leong, F. J. Lopez, F. Maleady-Crowe, M. McEntagart, F. Minneci, L. Moutsianas, M. Mueller, N. Murugaesu, A. C. Need, P. O’Donovan, C. A. Odhams, C. Patch, D. Perez-Gil, M. B. Pereira, J. Pullinger, T. Rahim, A. Rendon, T. Rogers, K. Savage, K. Sawant, R. H. Scott, A. Siddiq, A. Sieghart, S. C. Smith, Alona Sosinsky, A. Stuckey, M. Tanguy, A. L. Taylor Tavares, E. R. A. Thomas, S. R. Thompson, A. Tucci, M. J. Welland, E. Williams, K. Witkowska, S. M. Wood, James Allan, Garry Bisshopp, Stuart Blakemore, Jacqueline Boultwood, David Bruce, Francesca Buffa, Andrea Buggins, Gerald Cohen, Kate Cwynarski, Claire Dearden, Richard Dillon, Sarah Ennis, Francesco Falciani, George Follows, Francesco Forconi, Jade Forster, Christopher Fox, John Gribben, Anna Hockaday, Dena Howard, Andrew Jackson, Nagesh Kalakonda, Umair Khan, Philip Law, Pascal Lefevre, Ke Lin, Sandra Maseno, Paul Moss, Graham Packham, Claire Palles, Helen Parker, Piers Patten, Andrea Pellagatti, Guy Pratt, Alan Ramsay, Andy Rawstron, Matthew Rose-Zerilli, Joseph Slupsky, Tatjana Stankovic, Andrew Steele, Jonathan Strefford, Shankar Varadarajan, Dimitrios V. Vavoulis, Simon Wagner, David Westhead, Sarah Wordsworth, Jack Zhuang, Jane Gibson, Anika V. Prabhu, Ron Schwessinger, Daisy Jennings, Terena James, Uma Maheswari, Martí Duran-Ferrer, Piero Carninci, Samantha J. L. Knight, Robert Månsson, Jim Hughes, James Davies, Mark Ross, David Bentley, Jonathan C. Strefford, Stephen Devereux, Andrew R. Pettitt, Peter Hillmen, Mark J. Caulfield, Richard S. Houlston, José I. Martín-Subero & Anna Schuh. (2022) Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features. Nature Genetics 54:11, pages 1675-1689.
Crossref
Crossref
Saya Ichihara, Koji Nagao, Takehisa Sakaguchi, Chikashi Obuse & Takashi Sado. (2022) SmcHD1 underlies the formation of H3K9me3 blocks on the inactive X chromosome in mice. Development 149:15.
Crossref
Crossref
Shifeng Xue, Thanh Thao Nguyen Ly, Raunak S. Vijayakar, Jingyi Chen, Joel Ng, Ajay S. Mathuru, Frederique Magdinier & Bruno Reversade. (2022) HOX epimutations driven by maternal SMCHD1/LRIF1 haploinsufficiency trigger homeotic transformations in genetically wildtype offspring. Nature Communications 13:1.
Crossref
Crossref
Joseph S. Bowness, Tatyana B. Nesterova, Guifeng Wei, Lisa Rodermund, Mafalda Almeida, Heather Coker, Emma J. Carter, Artun Kadaster & Neil Brockdorff. (2022) Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1. Cell Reports 39:7, pages 110830.
Crossref
Crossref
Remko Goossens, Mara S. Tihaya, Anita van den Heuvel, Klorane Tabot-Ndip, Iris M. Willemsen, Stephen J. Tapscott, Román González-Prieto, Jer-Gung Chang, Alfred C. O. Vertegaal, Judit Balog & Silvère M. van der Maarel. (2021) A proteomics study identifying interactors of the FSHD2 gene product SMCHD1 reveals RUVBL1-dependent DUX4 repression. Scientific Reports 11:1.
Crossref
Crossref
Darina Šikrová, Vlad A. Cadar, Yavuz Ariyurek, Jeroen F.J. Laros, Judit Balog & Silvère M. van der Maarel. (2021) Adenine base editing of the DUX4 polyadenylation signal for targeted genetic therapy in facioscapulohumeral muscular dystrophy. Molecular Therapy - Nucleic Acids 25, pages 342-354.
Crossref
Crossref
Alexandra D. Gurzau, Christopher R. Horne, Yee-Foong Mok, Megan Iminitoff, Tracy A. Willson, Samuel N. Young, Marnie E. Blewitt & James M. Murphy. (2021) SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localization. Biochemical Journal 478:13, pages 2555-2569.
Crossref
Crossref
Zhuo Sun, Jinbo Fan & Yufeng Zhao. (2021) trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction. Genetics Research 2021, pages 1-7.
Crossref
Crossref
Xianrong Wong, Jevon A Cutler, Victoria E Hoskins, Molly Gordon, Anil K Madugundu, Akhilesh Pandey & Karen L Reddy. (2021) Mapping the micro-proteome of the nuclear lamina and lamina-associated domains. Life Science Alliance 4:5, pages e202000774.
Crossref
Crossref
Bénédicte Burlet, Selim Ramla, Cyril Fournier, Maria Jimena Abrey-Recalde, Camille Sauter, Marie-Lorraine Chrétien, Cédric Rossi, Yannis Duffourd, Sylviane Ragot, Céline Buriller, Benjamin Tournier, Caroline Chapusot, Nathalie Nadal, Jessica Racine, Julien Guy, François Bailly, Laurent Martin, Olivier Casasnovas, Jean-Noël Bastie, Denis Caillot, Juliette Albuisson, Cyril Broccardo, Catherine Thieblemont, Laurent Delva, Marc Maynadié, Romain Aucagne & Mary B. Callanan. (2021) Identification of novel, clonally stable, somatic mutations targeting transcription factors PAX5 and NKX2-3, the epigenetic regulator LRIF1, and BRAF in a case of atypical B-cell chronic lymphocytic leukemia harboring a t(14;18)(q32;q21). Molecular Case Studies 7:1, pages a005934.
Crossref
Crossref
Zhijun Huang, Jiyoung Yu, Wei CuiBenjamin K. JohnsonKyunggon Kim & Gerd P. Pfeifer. (2021) The chromosomal protein SMCHD1 regulates DNA methylation and the 2c-like state of embryonic stem cells by antagonizing TET proteins. Science Advances 7:4.
Crossref
Crossref
Alexandra D. Gurzau, Marnie E. Blewitt, Peter E. Czabotar, James M. Murphy & Richard W. Birkinshaw. (2020) Relating SMCHD1 structure to its function in epigenetic silencing. Biochemical Society Transactions 48:4, pages 1751-1763.
Crossref
Crossref
Junjun Cheng, Qiong Zhao, Yan Zhou, Liudi Tang, Muhammad Sheraz, Jinhong Chang & Ju-Tao Guo. (2020) Interferon Alpha Induces Multiple Cellular Proteins That Coordinately Suppress Hepadnaviral Covalently Closed Circular DNA Transcription. Journal of Virology 94:17.
Crossref
Crossref
Kenichi Kinjo, Keisuke Nagasaki, Koji Muroya, Erina Suzuki, Keisuke Ishiwata, Kazuhiko Nakabayashi, Atsushi Hattori, Koji Nagao, Ryu-Suke Nozawa, Chikashi Obuse, Kenji Miyado, Tsutomu Ogata, Maki Fukami & Mami Miyado. (2020) Rare variant of the epigenetic regulator SMCHD1 in a patient with pituitary hormone deficiency. Scientific Reports 10:1.
Crossref
Crossref
Kelan Chen, Richard W. Birkinshaw, Alexandra D. Gurzau, Iromi Wanigasuriya, Ruoyun WangMegan IminitoffJarrod J. SandowSamuel N. YoungPatrick J. HennessyTracy A. Willson, Denise A. Heckmann, Andrew I. Webb, Marnie E. Blewitt, Peter E. Czabotar & James M. Murphy. (2020) Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid–binding residues. Science Signaling 13:636.
Crossref
Crossref
Anna Greco, Remko Goossens, Baziel Engelen & Silvère M. Maarel. (2020) Consequences of epigenetic derepression in facioscapulohumeral muscular dystrophy. Clinical Genetics 97:6, pages 799-814.
Crossref
Crossref
Aleksandra Vančevska, Wareed Ahmed, Verena Pfeiffer, Marianna Feretzaki, Simon J Boulton & Joachim Lingner. (2020)
SMCHD
1 promotes
ATM
‐dependent
DNA
damage signaling and repair of uncapped telomeres
. The EMBO Journal 39:7.
Crossref
Crossref
Charis L. HimedaPeter L. Jones. (2019) The Genetics and Epigenetics of Facioscapulohumeral Muscular Dystrophy. Annual Review of Genomics and Human Genetics 20:1, pages 265-291.
Crossref
Crossref
Lars C. Pedersen, Kaoru Inoue, Susan Kim, Lalith Perera & Natalie D. Shaw. (2019) A ubiquitin-like domain is required for stabilizing the N-terminal ATPase module of human SMCHD1. Communications Biology 2:1.
Crossref
Crossref
Sabrina Sacconi, Audrey Briand-Suleau, Marilyn Gros, Christian Baudoin, Richard J.L.F. Lemmers, Sophie Rondeau, Nadira Lagha, Pilvi Nigumann, Chiara Cambieri, Angela Puma, Françoise Chapon, Tanya Stojkovic, Christophe Vial, Françoise Bouhour, Michelangelo Cao, Elena Pegoraro, Philippe Petiot, Anthony Behin, Bras Marc, Bruno Eymard, Andoni Echaniz-Laguna, Pascal Laforet, Leonardo Salviati, Marc Jeanpierre, Gaël Cristofari & Silvère M. van der Maarel. (2019) FSHD1 and FSHD2 form a disease continuum. Neurology 92:19, pages e2273-e2285.
Crossref
Crossref
Camille Dion, Stéphane Roche, Camille Laberthonnière, Natacha Broucqsault, Virginie Mariot, Shifeng Xue, Alexandra D Gurzau, Agnieszka Nowak, Christopher T Gordon, Marie-Cécile Gaillard, Claire El-Yazidi, Morgane Thomas, Andrée Schlupp-Robaglia, Chantal Missirian, Valérie Malan, Liham Ratbi, Abdelaziz Sefiani, Bernd Wollnik, Bernard Binetruy, Emmanuelle Salort Campana, Shahram Attarian, Rafaelle Bernard, Karine Nguyen, Jeanne Amiel, Julie Dumonceaux, James M Murphy, Jérôme Déjardin, Marnie E Blewitt, Bruno Reversade, Jérôme D Robin & Frédérique Magdinier. (2019)
SMCHD1 is involved in
de novo
methylation of the
DUX4
-encoding D4Z4 macrosatellite
. Nucleic Acids Research 47:6, pages 2822-2839.
Crossref
Crossref
Matthew Robert Paul, Andreas Hochwagen & Sevinç Ercan. (2018) Condensin action and compaction. Current Genetics 65:2, pages 407-415.
Crossref
Crossref
Nikolay Zernov & Mikhail Skoblov. (2019) Genotype-phenotype correlations in FSHD. BMC Medical Genomics 12:S2.
Crossref
Crossref
Michal R. Gdula, Tatyana B. Nesterova, Greta Pintacuda, Jonathan Godwin, Ye Zhan, Hakan Ozadam, Michael McClellan, Daniella Moralli, Felix Krueger, Catherine M. Green, Wolf Reik, Skirmantas Kriaucionis, Edith Heard, Job Dekker & Neil Brockdorff. (2019) The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome. Nature Communications 10:1.
Crossref
Crossref
Yosuke Hiramuki & Stephen J. Tapscott. (2018) Identification of SMCHD1 domains for nuclear localization, homo-dimerization, and protein cleavage. Skeletal Muscle 8:1.
Crossref
Crossref
Premi Haynes, Karol Bomsztyk & Daniel G. Miller. (2018) Sporadic DUX4 expression in FSHD myocytes is associated with incomplete repression by the PRC2 complex and gain of H3K9 acetylation on the contracted D4Z4 allele. Epigenetics & Chromatin 11:1.
Crossref
Crossref
Natasha Jansz, Tatyana Nesterova, Andrew Keniry, Megan Iminitoff, Peter F. Hickey, Greta Pintacuda, Osamu Masui, Simon Kobelke, Niall Geoghegan, Kelsey A. Breslin, Tracy A. Willson, Kelly Rogers, Graham F. Kay, Archa H. Fox, Haruhiko Koseki, Neil Brockdorff, James M. Murphy & Marnie E. Blewitt. (2018) Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway. Cell Reports 25:7, pages 1912-1923.e9.
Crossref
Crossref
Natasha Jansz, Andrew Keniry, Marie Trussart, Heidi Bildsoe, Tamara Beck, Ian D. Tonks, Arne W. Mould, Peter Hickey, Kelsey Breslin, Megan Iminitoff, Matthew E. Ritchie, Edwina McGlinn, Graham F. Kay, James M. Murphy & Marnie E. Blewitt. (2018) Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters. Nature Structural & Molecular Biology 25:9, pages 766-777.
Crossref
Crossref
Chen-Yu Wang, Teddy Jégu, Hsueh-Ping Chu, Hyun Jung Oh & Jeannie T. Lee. (2018) SMCHD1 Merges Chromosome Compartments and Assists Formation of Super-Structures on the Inactive X. Cell 174:2, pages 406-421.e25.
Crossref
Crossref
Alexandra D. Gurzau, Kelan Chen, Shifeng Xue, Weiwen Dai, Isabelle S. Lucet, Thanh Thao Nguyen Ly, Bruno Reversade, Marnie E. Blewitt & James M. Murphy. (2018) FSHD2- and BAMS-associated mutations confer opposing effects on SMCHD1 function. Journal of Biological Chemistry 293:25, pages 9841-9853.
Crossref
Crossref
Christopher H. Douse, Stuart Bloor, Yangci Liu, Maria Shamin, Iva A. Tchasovnikarova, Richard T. Timms, Paul J. Lehner & Yorgo Modis. (2018) Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms. Nature Communications 9:1.
Crossref
Crossref
Amanda G. Mason, Roderick C. Slieker, Judit Balog, Richard J. L. F. Lemmers, Chao-Jen Wong, Zizhen Yao, Jong-Won Lim, Galina N. Filippova, Enrico Ne, Rabi Tawil, Bas T. Heijmans, Stephen J. Tapscott & Silvère M. van der Maarel. (2017) SMCHD1 regulates a limited set of gene clusters on autosomal chromosomes. Skeletal Muscle 7:1.
Crossref
Crossref
Irene Cantone, Gopuraja Dharmalingam, Yi-Wah Chan, Anne-Celine Kohler, Boris Lenhard, Matthias Merkenschlager & Amanda G. Fisher. (2017) Allele-specific analysis of cell fusion-mediated pluripotent reprograming reveals distinct and predictive susceptibilities of human X-linked genes to reactivation. Genome Biology 18:1.
Crossref
Crossref
Yosuke Omae, Licht Toyo-oka, Hideki Yanai, Supalert Nedsuwan, Sukanya Wattanapokayakit, Nusara Satproedprai, Nat Smittipat, Prasit Palittapongarnpim, Pathom Sawanpanyalert, Wimala Inunchot, Ekawat Pasomsub, Nuanjun Wichukchinda, Taisei Mushiroda, Michiaki Kubo, Katsushi Tokunaga & Surakameth Mahasirimongkol. (2017) Pathogen lineage-based genome-wide association study identified CD53 as susceptible locus in tuberculosis. Journal of Human Genetics 62:12, pages 1015-1022.
Crossref
Crossref
Katherine E. Buxton, Julia Kennedy-Darling, Michael R. Shortreed, Nur Zafirah Zaidan, Michael Olivier, Mark Scalf, Rupa Sridharan & Lloyd M. Smith. (2017) Elucidating Protein–DNA Interactions in Human Alphoid Chromatin via Hybridization Capture and Mass Spectrometry. Journal of Proteome Research 16:9, pages 3433-3442.
Crossref
Crossref
Natasha Jansz, Kelan Chen, James M. Murphy & Marnie E. Blewitt. (2017) The Epigenetic Regulator SMCHD1 in Development and Disease. Trends in Genetics 33:4, pages 233-243.
Crossref
Crossref
Andrew O M Wilkie. (2017) Many faces of SMCHD1. Nature Genetics 49:2, pages 176-178.
Crossref
Crossref
Christopher T Gordon, Shifeng Xue, Gökhan Yigit, Hicham Filali, Kelan Chen, Nadine Rosin, Koh-ichiro Yoshiura, Myriam Oufadem, Tamara J Beck, Ruth McGowan, Alex C Magee, Janine Altmüller, Camille Dion, Holger Thiele, Alexandra D Gurzau, Peter Nürnberg, Dieter Meschede, Wolfgang Mühlbauer, Nobuhiko Okamoto, Vinod Varghese, Rachel Irving, Sabine Sigaudy, Denise Williams, S Faisal Ahmed, Carine Bonnard, Mung Kei Kong, Ilham Ratbi, Nawfal Fejjal, Meriem Fikri, Siham Chafai Elalaoui, Hallvard Reigstad, Christine Bole-Feysot, Patrick Nitschké, Nicola Ragge, Nicolas Lévy, Gökhan Tunçbilek, Audrey S M Teo, Michael L Cunningham, Abdelaziz Sefiani, Hülya Kayserili, James M Murphy, Chalermpong Chatdokmaiprai, Axel M Hillmer, Duangrurdee Wattanasirichaigoon, Stanislas Lyonnet, Frédérique Magdinier, Asif Javed, Marnie E Blewitt, Jeanne Amiel, Bernd Wollnik & Bruno Reversade. (2017) De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development. Nature Genetics 49:2, pages 249-255.
Crossref
Crossref
Karlien Mul, Marlinde L. van den Boogaard, Silvère M. van der Maarel & Baziel G.M. van Engelen. (2016) Integrating clinical and genetic observations in facioscapulohumeral muscular dystrophy. Current Opinion in Neurology 29:5, pages 606-613.
Crossref
Crossref
Stefan F. Pinter. (2016) A Tale of Two Cities: How Xist and its partners localize to and silence the bicompartmental X. Seminars in Cell & Developmental Biology 56, pages 19-34.
Crossref
Crossref
Kelan Chen, Renwick C.J. Dobson, Isabelle S. Lucet, Samuel N. Young, F. Grant Pearce, Marnie E. Blewitt & James M. Murphy. (2016) The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain. Biochemical Journal 473:12, pages 1733-1744.
Crossref
Crossref
Kelan Chen, Peter E. Czabotar, Marnie E. Blewitt & James M. Murphy. (2016) The hinge domain of the epigenetic repressor Smchd1 adopts an unconventional homodimeric configuration. Biochemical Journal 473:6, pages 733-742.
Crossref
Crossref