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Article

CtBPs Promote Cell Survival through the Maintenance of Mitotic Fidelity

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Pages 4539-4551 | Received 06 Apr 2009, Accepted 01 Jun 2009, Published online: 21 Mar 2023

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Subir K. Ray, H. Joyce Li, Eric Metzger, Roland Schüle & Andrew B. Leiter. (2014) CtBP and Associated LSD1 Are Required for Transcriptional Activation by NeuroD1 in Gastrointestinal Endocrine Cells. Molecular and Cellular Biology 34:12, pages 2308-2317.
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YingYing He, Zhicheng He, Jian Lin, Cheng Chen, Yuanzhi Chen & Shubai Liu. (2021) CtBP1/2 differentially regulate genomic stability and DNA repair pathway in high-grade serous ovarian cancer cell. Oncogenesis 10:7.
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Liang Chen, Lu Wang, Jun Qin & De-Sheng Wei. (2020) CtBP2 interacts with ZBTB18 to promote malignancy of glioblastoma. Life Sciences 262, pages 118477.
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Mira Kreuzer, Arindam Banerjee, Charles N. Birts, Matthew Darley, Ali Tavassoli, Mircea Ivan & Jeremy P. Blaydes. (2020) Glycolysis, via NADH‐dependent dimerisation of CtBPs, regulates hypoxia‐induced expression of CAIX and stem‐like breast cancer cell survival. FEBS Letters 594:18, pages 2988-3001.
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Charles N. Birts, Arindam BanerjeeMatthew DarleyCharles R. Dunlop, Sarah NelsonSharandip K. NijjarRachel Parker, Jonathan West, Ali Tavassoli, Matthew J. J. Rose-ZerilliJeremy P. Blaydes. (2020) p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators. Science Signaling 13:630.
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Yu Deng, Wanjun Guo, Guancheng Li, Shuang Li, Hong Li, Xinyan Li, Bei Niu, Mingzhu Song, Yamei Zhang, Zhijian Xu & Fulun Li. (2020) Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1. Journal of Breast Cancer 23:1, pages 20.
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Arindam Banerjee, Charles N Birts, Matthew Darley, Rachel Parker, Alex H Mirnezami, Jonathan West, Ramsey I Cutress, Stephen A Beers, Matthew J J Rose-Zerilli & Jeremy P Blaydes. (2019) Stem cell-like breast cancer cells with acquired resistance to metformin are sensitive to inhibitors of NADH-dependent CtBP dimerization. Carcinogenesis 40:7, pages 871-882.
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Lu Chen, Yang Yang, Liwei Xu, Rui Liu & Yali Wang. (2017) Integrated gene expression profiling and chromatin immunoprecipitation followed by sequencing: Analysis of the C-terminal binding protein in breast cancer. Journal of Obstetrics and Gynaecology Research 43:9, pages 1472-1480.
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Subir K. Ray, Hui J. Li & Andrew B. Leiter. (2017) Oligomeric form of C-terminal-binding protein coactivates NeuroD1-mediated transcription. FEBS Letters 591:1, pages 205-212.
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Umar Raza, Özge Saatci, Stefan Uhlmann, Suhail A Ansari, Erol Eyüpoğlu, Emre Yurdusev, Merve Mutlu, Pelin Gülizar Ersan, Mustafa Kadri Altundağ, Jitao David Zhang, Hayriye Tatlı Doğan, Gülnur Güler & Özgür Şahin. (2016) The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer. Oncotarget 7:31, pages 49859-49877.
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Chengjin Zhao, Yifen Shen, Xuelei Tao, Jian Xu, Junjie Lu, Chao Liu, Zhiwei Xu, Qing Tang, Tao Tao & Xiubing Zhang. (2016) Silencing of CtBP1 suppresses the migration in human glioma cells. Journal of Molecular Histology 47:3, pages 297-304.
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Yanli Zhang, Jamie Sui-Lam Kwok, Pui-Wah Choi, Minghua Liu, Junzheng Yang, Margit Singh, Shu-Kay Ng, William R. Welch, Michael G. Muto, Stephen KW Tsui, Stephen P. Sugrue, Ross S. Berkowitz & Shu-Wing Ng. (2016) Pinin interacts with C-terminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells. Oncotarget 7:10, pages 11397-11411.
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Katherine E. WilliamsGeorge A. LemieuxMaria E. HassisAdam B. Olshen, Susan J. FisherZena Werb. (2016) Quantitative proteomic analyses of mammary organoids reveals distinct signatures after exposure to environmental chemicals. Proceedings of the National Academy of Sciences 113:10.
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Melanie A. Blevins, Jennifer Kouznetsova, Aaron B. Krueger, Rebecca King, Lesley Mathews Griner, Xin Hu, Noel Southall, Juan J. Marugan, Qinghong Zhang, Marc Ferrer & Rui Zhao. (2015) Small Molecule, NSC95397, Inhibits the CtBP1-Protein Partner Interaction and CtBP1-Mediated Transcriptional Repression. SLAS Discovery 20:5, pages 663-672.
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Timothy J Underwood, Annette L Hayden, Mathieu Derouet, Edwin Garcia, Fergus Noble, Michael J White, Steve Thirdborough, Abbie Mead, Nicholas Clemons, Massimiliano Mellone, Chudy Uzoho, John N Primrose, Jeremy P Blaydes & Gareth J Thomas. (2015) Cancer‐associated fibroblasts predict poor outcome and promote periostin‐dependent invasion in oesophageal adenocarcinoma. The Journal of Pathology 235:3, pages 466-477.
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Ken-ichi Takayama & Satoshi Inoue. 2015. Long Noncoding RNAs. Long Noncoding RNAs 191 210 .
Trisha R. Stankiewicz, Josie J. Gray, Aimee N. Winter & Daniel A. Linseman. (2014) C-terminal binding proteins: central players in development and disease. Biomolecular Concepts 5:6, pages 489-511.
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Ken-ichi Takayama, Takashi Suzuki, Tetsuya Fujimura, Tomohiko Urano, Satoru Takahashi, Yukio Homma & Satoshi Inoue. (2014) CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression. Cancer Research 74:22, pages 6542-6553.
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Changwen Zhang, Chao Gao, Yong Xu & Zhihong Zhang. (2014) CtBP2 could promote prostate cancer cell proliferation through c-Myc signaling. Gene 546:1, pages 73-79.
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Xiancheng Liu, Ninghua Yao, Jing Qian & Huiwei Huang. (2014) High expression and prognostic role of CAP1 and CtBP2 in breast carcinoma: associated with E-cadherin and cell proliferation. Medical Oncology 31:3.
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Taymaa May, Junzheng Yang, Melina Shoni, Shubai Liu, Housheng He, Reddy Gali, Shu-Kay Ng, Christopher Crum, Ross S. Berkowitz & Shu-Wing Ng. (2013) BRCA1 Expression Is Epigenetically Repressed in Sporadic Ovarian Cancer Cells by Overexpression of C-Terminal Binding Protein 2. Neoplasia 15:6, pages 600-IN6.
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Chengqi Guan, Hui Shi, Huijie Wang, Jianguo Zhang, Wenkai Ni, Buyou Chen, Sicong Hou, Xiaojing Yang, Aiguo Shen & Runzhou Ni. (2013) CtBP2 contributes to malignant development of human esophageal squamous cell carcinoma by regulation of p16 INK4A . Journal of Cellular Biochemistry 114:6, pages 1343-1354.
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Ken-ichi Takayama, Kuniko Horie-Inoue, Shintaro Katayama, Takashi Suzuki, Shuichi Tsutsumi, Kazuhiro Ikeda, Tomohiko Urano, Tetsuya Fujimura, Kiyoshi Takagi, Satoru Takahashi, Yukio Homma, Yasuyoshi Ouchi, Hiroyuki Aburatani, Yoshihide Hayashizaki & Satoshi Inoue. (2013) Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer. The EMBO Journal 32:12, pages 1665-1680.
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Hui Deng, Jing Liu, Yu Deng, Gangwen Han, Yiqun G. Shellman, Steven E. Robinson, John J. Tentler, William A. Robinson, David A. Norris, Xiao-Jing Wang & Qinghong Zhang. (2013) CtBP1 Is Expressed in Melanoma and Represses the Transcription of p16INK4a and Brca1. Journal of Investigative Dermatology 133:5, pages 1294-1301.
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Gangwen Han, Li Bian, Fulun Li, Ana Cotrim, Donna Wang, Jianbo Lu, Yu Deng, Gregory Bird, Anastasia Sowers, James B Mitchell, J Silvio Gutkind, Rui Zhao, David Raben, Peter ten Dijke, Yosef Refaeli, Qinghong Zhang & Xiao-Jing Wang. (2013) Preventive and therapeutic effects of Smad7 on radiation-induced oral mucositis. Nature Medicine 19:4, pages 421-428.
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Caroline C. HuardCédric S. TremblayKathrin Helsper, Marie-Chantal DelisleDetlev Schindler, Georges Lévesque & Madeleine Carreau. (2013) Fanconi anemia proteins interact with CtBP1 and modulate the expression of the Wnt antagonist Dickkopf-1. Blood 121:10, pages 1729-1739.
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Li-Jun Di, Jung S. Byun, Madeline M. Wong, Clay Wakano, Tara Taylor, Sven Bilke, Songjoon Baek, Kent Hunter, Howard Yang, Maxwell Lee, Cecilia Zvosec, Galina Khramtsova, Fan Cheng, Charles M. Perou, C. Ryan Miller, Rachel Raab, Olufunmilayo I. Olopade & Kevin Gardner. (2013) Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer. Nature Communications 4:1.
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Jae-Hwan Kim, Soo-Youn Choi, Byung-Hee Kang, Soon-Min Lee, Hyung Soon Park, Gum-Yong Kang, Joo Young Bang, Eun-Jung Cho & Hong-Duk Youn. (2013) AMP-activated protein kinase phosphorylates CtBP1 and down-regulates its activity. Biochemical and Biophysical Research Communications 431:1, pages 8-13.
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C N Birts, L M Bergman & J P Blaydes. (2010) CtBPs promote mitotic fidelity through their activities in the cell nucleus. Oncogene 30:11, pages 1272-1280.
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Charles N. Birts, Rachael Harding, Gehan Soosaipillai, Trisha Halder, Ali Azim-Araghi, Matthew Darley, Ramsey I. Cutress, Adrian C. Bateman & Jeremy P. Blaydes. (2011) Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance. Biology of the Cell 103:1, pages 1-19.
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Yuzhen Zhang, Shanru Li, Lijun Yuan, Ying Tian, Joel Weidenfeld, Jifu Yang, Feiyan Liu, Ann L. Chokas & Edward E. Morrisey. (2010) Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms. Genes & Development 24:16, pages 1746-1757.
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