Xian Zhao, Keisuke Kiyozuka, Akimitsu Konishi, Reika Kawabata-Iwakawa, Yoji Andrew Minamishima & Hideru Obinata. (2023) Actin-binding protein filamin B regulates the cell-surface retention of endothelial sphingosine 1-phosphate receptor 1. Journal of Biological Chemistry 299:7, pages 104851.
Crossref
Corina M. Stewart, Yuxia Bo, Kathy Fu, Mable Chan, Robert Kozak, Kim Yang-Ping Apperley, Geneviève Laroche, Redaet Daniel, André M. Beauchemin, Gary Kobinger, Darwyn Kobasa & Marceline Côté. (2023) Sphingosine Kinases Promote Ebola Virus Infection and Can Be Targeted to Inhibit Filoviruses, Coronaviruses, and Arenaviruses Using Late Endocytic Trafficking to Enter Cells. ACS Infectious Diseases 9:5, pages 1064-1077.
Crossref
Lavinia Arseni, Rakesh Sharma, Norman Mack, Deepthi Nagalla, Sibylle Ohl, Thomas Hielscher, Mahak Singhal, Robert Pilz, Hellmut Augustin, Roger Sandhoff, Christel Herold-Mende, Björn Tews, Peter Lichter & Martina Seiffert. (2023) Sphingosine-1-Phosphate Recruits Macrophages and Microglia and Induces a Pro-Tumorigenic Phenotype That Favors Glioma Progression. Cancers 15:2, pages 479.
Crossref
Marc Micó-Carnero, Araní Casillas-Ramírez, Alfredo Sánchez-González, Carlos Rojano-Alfonso & Carmen Peralta. (2022) The Role of Neuregulin-1 in Steatotic and Non-Steatotic Liver Transplantation from Brain-Dead Donors. Biomedicines 10:5, pages 978.
Crossref
Mengqiao Cui, Verena GöbelHongjie Zhang. (2021) Uncovering the ‘sphinx’ of sphingosine 1‐phosphate signalling: from cellular events to organ morphogenesis. Biological Reviews 97:1, pages 251-272.
Crossref
Lan Wu, Yan Cheng, Shunxiang Peng, Wensheng Zhang & Chaoxiong Zhang. (2021) Sphingosine Kinase 1 Plays an Important Role in Atorvastatin-Mediated Anti-Inflammatory Effect against Acute Lung Injury. Mediators of Inflammation 2021, pages 1-14.
Crossref
Islamy Rahma Hutami, Takashi Izawa, Tsendsuren Khurel-Ochir, Takuma Sakamaki, Akihiko Iwasa & Eiji Tanaka. (2021) Macrophage Motility in Wound Healing Is Regulated by HIF-1α via S1P Signaling. International Journal of Molecular Sciences 22:16, pages 8992.
Crossref
Min Liu, Zhangqi Xu, Cheng Zhang, Chunxia Yang, Jiaxing Feng, Yiqing Lu, Wen Zhang, Wenwen Chen, Xiaoyang Xu, Xiaoxia Sun, Mingyang Yang, Wei Liu, Tianhua Zhou & Yuehong Yang. (2021) NudC L279P Mutation Destabilizes Filamin A by Inhibiting the Hsp90 Chaperoning Pathway and Suppresses Cell Migration. Frontiers in Cell and Developmental Biology 9.
Crossref
Jie Zhou, Xinmei Kang, Hanxiang An, Yun Lv & Xin Liu. (2021) The function and pathogenic mechanism of filamin A. Gene 784, pages 145575.
Crossref
MelissaR Pitman, Martin K. Oehler & Stuart M. Pitson. (2021) Sphingolipids as multifaceted mediators in ovarian cancer. Cellular Signalling 81, pages 109949.
Crossref
Weiwei Shi, Ding Ma, Yin Cao, Lili Hu, Shuwen Liu, Dongliang Yan, Shan Zhang, Guang Zhang, Zhongxia Wang, Junhua Wu & Chunping Jiang. (2021) SphK2/S1P Promotes Metastasis of Triple-Negative Breast Cancer Through the PAK1/LIMK1/Cofilin1 Signaling Pathway. Frontiers in Molecular Biosciences 8.
Crossref
Hayato Urushima, Hideto Yuasa, Tsutomu Matsubara, Noriyuki Kuroda, Yaiko Hara, Kouji Inoue, Kenjiro Wake, Tetsuji Sato, Scott L. Friedman & Kazuo Ikeda. (2021) Activation of Hepatic Stellate Cells Requires Dissociation of E-Cadherin–Containing Adherens Junctions with Hepatocytes. The American Journal of Pathology 191:3, pages 438-453.
Crossref
Yamila I. Rodriguez, Ludmila E. Campos, Melina G. Castro, Nadia Bannoud, Ada G. Blidner, Verónica P. Filippa, Diego O. Croci, Gabriel A. Rabinovich & Sergio E. Alvarez. (2020) Tumor Necrosis Factor Receptor-1 (p55) Deficiency Attenuates Tumor Growth and Intratumoral Angiogenesis and Stimulates CD8+ T Cell Function in Melanoma. Cells 9:11, pages 2469.
Crossref
Gabriela Schneider. 2020. Tumor Microenvironment. Tumor Microenvironment
129
153
.
Chiara Sassoli, Federica Pierucci, Sandra Zecchi-Orlandini & Elisabetta Meacci. (2019) Sphingosine 1-Phosphate (S1P)/ S1P Receptor Signaling and Mechanotransduction: Implications for Intrinsic Tissue Repair/Regeneration. International Journal of Molecular Sciences 20:22, pages 5545.
Crossref
Mengyao YuAdrien GeorgesNathan R. TuckerSergiy KyryachenkoKatelyn ToomerJean-Jacques SchottFrancesca N. DellingLeticia Fernandez-FrieraJorge SolisPatrick T. EllinorRobert A. LevineSusan A. SlaugenhauptAlbert A. HagègeChristian DinaXavier JeunemaitreDavid J. MilanRussell A. Norris & Nabila Bouatia-Naji. (2019)
Genome-Wide Association Study–Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest
GLIS1
as a Susceptibility Gene for Mitral Valve Prolapse
. Circulation: Genomic and Precision Medicine 12:5.
Crossref
Manmeet Bhalla, Hoan Van Ngo, Gaurav Chandra Gyanwali & Keith Ireton. (2019)
The Host Scaffolding Protein Filamin A and the Exocyst Complex Control Exocytosis during InlB-Mediated Entry of
Listeria monocytogenes
. Infection and Immunity 87:1.
Crossref
Michael J. Pulkoski-Gross & Lina M. Obeid. (2018) Molecular mechanisms of regulation of sphingosine kinase 1. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1863:11, pages 1413-1422.
Crossref
Panfeng Fu, Mark Shaaya, Anantha Harijith, Jeffrey R. Jacobson, Andrei Karginov & Viswanathan Natarajan. 2018. Membranes in Pulmonary Vascular Disease. Membranes in Pulmonary Vascular Disease
1
31
.
Sarah E. Nicholas, Tyler G. Rowsey, Shrestha Priyadarsini, Nawajes A. Mandal & Dimitrios Karamichos. (2017) Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma. PLOS ONE 12:8, pages e0182390.
Crossref
Nigel Pyne & Susan Pyne. (2017) Sphingosine 1-Phosphate Receptor 1 Signaling in Mammalian Cells. Molecules 22:3, pages 344.
Crossref
Santiago Lima, Sheldon Milstien & Sarah Spiegel. (2017) Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking. Journal of Biological Chemistry 292:8, pages 3074-3088.
Crossref
Melina G. Castro, Ludmila E. Campos, Yamila I. Rodriguez & Sergio E. Alvarez. 2018. Sphingosine-1-Phosphate. Sphingosine-1-Phosphate
117
131
.
Yamila I. Rodriguez, Ludmila E. Campos, Melina G. Castro, Ahmed Aladhami, Carole A. Oskeritzian & Sergio E. Alvarez. (2016) Sphingosine-1 Phosphate: A New Modulator of Immune Plasticity in the Tumor Microenvironment. Frontiers in Oncology 6.
Crossref
Sathya Narayanan Patmanathan, Steven P. Johnson, Sook Ling Lai, Suthashini Panja Bernam, Victor Lopes, Wenbin Wei, Maha Hafez Ibrahim, Federico Torta, Pradeep Narayanaswamy, Markus R. Wenk, Deron R. Herr, Paul G. Murray, Lee Fah Yap & Ian C. Paterson. (2016) Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2. Scientific Reports 6:1.
Crossref
Christopher White, Heba Alshaker, Colin Cooper, Matthias Winkler & Dmitri Pchejetski. (2016) The emerging role of FTY720 (Fingolimod) in cancer treatment. Oncotarget 7:17, pages 23106-23127.
Crossref
David P. Dimasi, Stuart M. Pitson & Claudine S. Bonder. (2016) Examining the Role of Sphingosine Kinase-2 in the Regulation of Endothelial Cell Barrier Integrity. Microcirculation 23:3, pages 248-265.
Crossref
Qian-Qian Shao, Tai-Ping Zhang, Wen-Jing Zhao, Zi-Wen Liu, Lei You, Li Zhou, Jun-Chao Guo & Yu-Pei Zhao. (2015) Filamin A: Insights into its Exact Role in Cancers. Pathology & Oncology Research 22:2, pages 245-252.
Crossref
Panfeng Fu, Peter V. Usatyuk, Jeffrey Jacobson, Anne E. Cress, Joe G. N. Garcia, Ravi Salgia & Viswanathan Natarajan. (2015) Role Played by Paxillin and Paxillin Tyrosine Phosphorylation in Hepatocyte Growth Factor/Sphingosine‐1‐Phosphate‐Mediated Reactive Oxygen Species Generation, Lamellipodia Formation, and Endothelial Barrier Function. Pulmonary Circulation 5:4, pages 619-630.
Crossref
Kristi Krebs, Anu Ruusmann, Grethel Simonlatser & Teet Velling. (2015) Expression of FLNa in human melanoma cells regulates the function of integrin α1β1 and phosphorylation and localisation of PKB/AKT/ERK1/2 kinases. European Journal of Cell Biology 94:12, pages 564-575.
Crossref
Joice de Faria Poloni & Diego Bonatto. (2015) Systems Chemo-Biology and Transcriptomic Meta-Analysis Reveal the Molecular Roles of Bioactive Lipids in Cardiomyocyte Differentiation. Journal of Cellular Biochemistry 116:9, pages 2018-2031.
Crossref
Lei Xiu, Na Chang, Le Yang, Xin Liu, Lin Yang, Jingjing Ge & Liying Li. (2015) Intracellular Sphingosine 1-Phosphate Contributes to Collagen Expression of Hepatic Myofibroblasts in Human Liver Fibrosis Independent of Its Receptors. The American Journal of Pathology 185:2, pages 387-398.
Crossref
Bruce A. Stanley, Tye Deering & Todd E. Fox. 2015. Bioactive Sphingolipids in Cancer Biology and Therapy. Bioactive Sphingolipids in Cancer Biology and Therapy
359
384
.
Alan Hammer & Maria Diakonova. 2015. Recent Advances in Prolactin Research. Recent Advances in Prolactin Research
97
137
.
Heba Alshaker, Jonathan Krell, Adam E Frampton, Jonathan Waxman, Oleg Blyuss, Alexey Zaikin, Mathias Winkler, Justin Stebbing, Ernesto Yagüe & Dmitri Pchejetski. (2014) Leptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathway. Breast Cancer Research 16:5.
Crossref
Eugene Y. Kim, Jamie L. Sturgill, Nitai C. Hait, Dorit Avni, Evelyn C. Valencia, Michael Maceyka, Santiago Lima, Jeremy Allegood, Wei‐Ching Huang, Shijun Zhang, Sheldon Milstien, Daniel Conrad & Sarah Spiegel. (2014) Role of sphingosine kinase 1 and sphingosine‐1‐phosphate in CD40 signaling and IgE class switching. The FASEB Journal 28:10, pages 4347-4358.
Crossref
Domenico M. Taglieri, Masuko Ushio-Fukai & Michelle M. Monasky. (2014) P21-activated kinase in inflammatory and cardiovascular disease. Cellular Signalling 26:9, pages 2060-2069.
Crossref
Shunya Kondo, Alessia Bottos, Jeremy C. Allegood, Regis Masson, Francisca G. Maurer, Christel Genoud, Patrick Kaeser, Andrea Huwiler, Masato Murakami, Sarah Spiegel & Nancy E. Hynes. (2014) Memo Has a Novel Role in S1P Signaling and Crucial for Vascular Development. PLoS ONE 9:4, pages e94114.
Crossref
Olivier Cuvillier. 2014. Molecular Mechanisms of Angiogenesis. Molecular Mechanisms of Angiogenesis
199
217
.
Rosalinda M Savoy & Paramita M Ghosh. (2013) The dual role of filamin A in cancer: can't live with (too much of) it, can't live without it. Endocrine-Related Cancer 20:6, pages R341-R356.
Crossref
Benjamin Weichand, Nicole Weis, Andreas Weigert, Nina Grossmann, Bodo Levkau & Bernhard Brüne. (2013) Apoptotic cells enhance sphingosine-1-phosphate receptor 1 dependent macrophage migration. European Journal of Immunology 43:12, pages 3306-3313.
Crossref
Heidi A. Neubauer & Stuart M. Pitson. (2013) Roles, regulation and inhibitors of sphingosine kinase 2. FEBS Journal 280:21, pages 5317-5336.
Crossref
Craig T. Wallington‐Beddoe, Kenneth F. Bradstock & Linda J. Bendall. (2013) Oncogenic properties of sphingosine kinases in haematological malignancies. British Journal of Haematology 161:5, pages 623-638.
Crossref
Lian-Wen Yuan, Dong-Cai Liu & Zhu-Lin Yang. (2013) Correlation of S1P1 and ERp29 expression to progression, metastasis, and poor prognosis of gallbladder adenocarcinoma. Hepatobiliary & Pancreatic Diseases International 12:2, pages 189-195.
Crossref
Melissa R. Pitman, Kate E. Jarman, Tamara M. Leclercq, Duyen H. Pham & Stuart M. Pitson. 2013. Lysophospholipid Receptors. Lysophospholipid Receptors
153
183
.
Alan HammerLeah RiderPeter OladimejiLeslie CookQuanwen Li, Raymond R. Mattingly & Maria Diakonova. (2013) Tyrosyl Phosphorylated PAK1 Regulates Breast Cancer Cell Motility in Response to Prolactin through Filamin A. Molecular Endocrinology 27:3, pages 455-465.
Crossref
K. Alexa Orr GandyDaniel CanalsMohamad AdadaMasayuki WadaPatrick RoddyAshley J. SniderYusuf A. HannunLina M. Obeid. (2013) Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins. Biochemical Journal 449:3, pages 661-672.
Crossref
Jan Ohotski, Joanne Edwards, Beatrix Elsberger, Carol Watson, Clare Orange, Elizabeth Mallon, Susan Pyne & Nigel J. Pyne. (2013) Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer. International Journal of Cancer 132:3, pages 605-616.
Crossref
Huasheng Chan & Stuart M. Pitson. (2013) Post-translational regulation of sphingosine kinases. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1831:1, pages 147-156.
Crossref
Nigel J. Pyne, Gerald Dubois & Susan Pyne. (2013) Role of sphingosine 1-phosphate and lysophosphatidic acid in fibrosis. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1831:1, pages 228-238.
Crossref
Heba Alshaker, Lysann Sauer, Danielle Monteil, Silvia Ottaviani, Shyam Srivats, Torsten Böhler & Dmitri Pchejetski. 2013. The Role of Sphingolipids in Cancer Development and Therapy. The Role of Sphingolipids in Cancer Development and Therapy
143
200
.
K. Alexa Orr Gandy & Lina M. Obeid. 2013. Sphingolipids in Disease. Sphingolipids in Disease
275
303
.
Jian Pan, Yan-Fang Tao, Zhuan Zhou, Bang-rong Cao, Shui-Yan Wu, Yan-Lan Zhang, Shao-Yan Hu, Wen-Li Zhao, Jian Wang, Guo-Liang Lou, Zhen Li, Xing Feng & Jian Ni. (2011) An novel role of sphingosine kinase-1 (SPHK1) in the invasion and metastasis of esophageal carcinoma. Journal of Translational Medicine 9:1.
Crossref
Jessie W. Yester, Etsegenet Tizazu, Kuzhuvelil B. Harikumar & Tomasz Kordula. (2011) Extracellular and intracellular sphingosine-1-phosphate in cancer. Cancer and Metastasis Reviews 30:3-4, pages 577-597.
Crossref
Susan Pyne, Robert Bittman & Nigel J. Pyne. (2011) Sphingosine Kinase Inhibitors and Cancer: Seeking the Golden Sword of Hercules. Cancer Research 71:21, pages 6576-6582.
Crossref
Dmitri Pchejetski, Torsten Böhler, Justin Stebbing & Jonathan Waxman. (2011) Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer. Nature Reviews Urology 8:10, pages 569-578.
Crossref
Susan Pyne & Nigel J. Pyne. (2011) Translational aspects of sphingosine 1-phosphate biology. Trends in Molecular Medicine 17:8, pages 463-472.
Crossref
Eve-Ellen Govek, Mary E. Hatten & Linda Van Aelst. (2011) The role of Rho GTPase proteins in CNS neuronal migration. Developmental Neurobiology 71:6, pages 528-553.
Crossref
Stuart M. Pitson. (2011) Regulation of sphingosine kinase and sphingolipid signaling. Trends in Biochemical Sciences 36:2, pages 97-107.
Crossref
Nigel J. Pyne & Susan Pyne. (2010) Sphingosine 1-phosphate and cancer. Nature Reviews Cancer 10:7, pages 489-503.
Crossref
Sergio E. Alvarez, Kuzhuvelil B. Harikumar, Nitai C. Hait, Jeremy Allegood, Graham M. Strub, Eugene Y. Kim, Michael Maceyka, Hualiang Jiang, Cheng Luo, Tomasz Kordula, Sheldon Milstien & Sarah Spiegel. (2010) Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature 465:7301, pages 1084-1088.
Crossref
Ashley J. Snider, K. Alexa Orr Gandy & Lina M. Obeid. (2010) Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation. Biochimie 92:6, pages 707-715.
Crossref
Alex-Xianghua Zhou, John H. Hartwig & Levent M. Akyürek. (2010) Filamins in cell signaling, transcription and organ development. Trends in Cell Biology 20:2, pages 113-123.
Crossref
Jeremy A. Hengst, Jacquelyn M. Guilford, Todd E. Fox, Xujun Wang, Elizabeth J. Conroy & Jong K. Yun. (2009) Sphingosine kinase 1 localized to the plasma membrane lipid raft microdomain overcomes serum deprivation induced growth inhibition. Archives of Biochemistry and Biophysics 492:1-2, pages 62-73.
Crossref
Jennifer R. Gamble, Wai Y. Sun, Xiaochun Li, Christopher N. Hahn, Stuart M. Pitson, Mathew A. Vadas & Claudine S. Bonder. (2009) Sphingosine Kinase-1 Associates with Integrin αVβ3 to Mediate Endothelial Cell Survival. The American Journal of Pathology 175:5, pages 2217-2225.
Crossref
Dmitri Kapitonov, Jeremy C. Allegood, Clint Mitchell, Nitai C. Hait, Jorge A. Almenara, Jeffrey K. Adams, Robert E. Zipkin, Paul Dent, Tomasz Kordula, Sheldon Milstien & Sarah Spiegel. (2009) Targeting Sphingosine Kinase 1 Inhibits Akt Signaling, Induces Apoptosis, and Suppresses Growth of Human Glioblastoma Cells and Xenografts. Cancer Research 69:17, pages 6915-6923.
Crossref
Roger H. Kim, Kazuaki Takabe, Sheldon Milstien & Sarah Spiegel. (2009) Export and functions of sphingosine-1-phosphate. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1791:7, pages 692-696.
Crossref
Huan Yu, Taro Okada, Masako Kobayashi, Dina M. Abo-Elmatty, Saleem Jahangeer & Shun-ichi Nakamura. (2009) Roles of extracellular and intracellular sphingosine 1-phosphate in cell migration. Genes to Cells 14:5, pages 597-605.
Crossref
Michael Maceyka, Sheldon Milstien & Sarah Spiegel. (2009) Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling. Journal of Lipid Research 50, pages S272-S276.
Crossref