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Barbara Tedesco, Leen Vendredy, Vincent Timmerman & Angelo Poletti. (2023) The chaperone-assisted selective autophagy complex dynamics and dysfunctions. Autophagy 19:6, pages 1619-1641.
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Articles from other publishers (56)
Hui Xu, Yi-Yang Liu, Lin-Seng Li & You-Shuo Liu. (2023) Sirtuins at the Crossroads between Mitochondrial Quality Control and Neurodegenerative Diseases: Structure, Regulation, Modifications, and Modulators. Aging and disease 14:3, pages 794.
Crossref
Crossref
Abantika Chakraborty & Adrienne L. Edkins. 2023. The Networking of Chaperones by Co-Chaperones. The Networking of Chaperones by Co-Chaperones
351
387
.
Sunny Kumar, Malini Basu & Mrinal K. Ghosh. (2022) Chaperone-assisted E3 ligase CHIP: A double agent in cancer. Genes & Diseases 9:6, pages 1521-1555.
Crossref
Crossref
Li‐Bo Liu, Si‐Hui Huang, Hong‐Liang Qiu, Xian‐Feng Cen, Ying‐Ying Guo, Dan Li, Yu‐Lan Ma, Man Xu & Qi‐Zhu Tang. (2022) Limonin stabilises sirtuin 6 (SIRT6) by activating ubiquitin specific peptidase 10 (USP10) in cardiac hypertrophy. British Journal of Pharmacology 179:18, pages 4516-4533.
Crossref
Crossref
Cheng Chen, Caidie Xie, Yiqing Xiong, Hanzhang Wu, Lin Wu, Jingfeng Zhu, Changying Xing & Huijuan Mao. (2022) Damage of uremic myocardium by p-cresyl sulfate and the ameliorative effect of Klotho by regulating SIRT6 ubiquitination. Toxicology Letters 367, pages 19-31.
Crossref
Crossref
Yueying Yang, Man Zhu, Jing Liang, Hui Wang, Dejuan Sun, Hua Li & Lixia Chen. (2022) SIRT6 mediates multidimensional modulation to maintain organism homeostasis. Journal of Cellular Physiology 237:8, pages 3205-3221.
Crossref
Crossref
Mariana Bresque, Karina Cal, Valentina Pérez-Torrado, Laura Colman, Jorge Rodríguez-Duarte, Cecilia Vilaseca, Leonardo Santos, María Pía Garat, Santiago Ruiz, Frances Evans, Rosina Dapueto, Paola Contreras, Aldo Calliari & Carlos Escande. (2022) SIRT6 stabilization and cytoplasmic localization in macrophages regulates acute and chronic inflammation in mice. Journal of Biological Chemistry 298:3, pages 101711.
Crossref
Crossref
Zhenyang Guo, Peng Li, Junbo Ge & Hua Li. (2022) SIRT6 in Aging, Metabolism, Inflammation and Cardiovascular Diseases. Aging and disease 13:6, pages 1787.
Crossref
Crossref
Sukanya Raghu, Arathi Bangalore Prabhashankar, Bhoomika Shivanaiah, Ekta Tripathi & Nagalingam Ravi Sundaresan. 2022. Metabolism and Epigenetic Regulation: Implications in Cancer. Metabolism and Epigenetic Regulation: Implications in Cancer
337
360
.
Shilin Yuan, Guanghong Liao, Menghuan Zhang, Yuanfei Zhu, Weidi Xiao, Kun Wang, Chuanyin Li, Caiwei Jia, Na Sun, Axel Walch, Daming Gao, Ping Xu, Qiang Deng, Jian Zhang, He Wang & Ronggui Hu. (2021) Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBV. Cell Discovery 7:1.
Crossref
Crossref
Catarina Dias, Erisa Nita, Jakub Faktor, Ailish C. Tynan, Lenka Hernychova, Borivoj Vojtesek, Jesper Nylandsted, Ted R. Hupp, Tilo Kunath & Kathryn L. Ball. (2021) CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity. iScience 24:8, pages 102878.
Crossref
Crossref
Yan Zhang, Gengshou Xia & Qianggen Zhu. (2021) Conserved and Unique Roles of Chaperone-Dependent E3 Ubiquitin Ligase CHIP in Plants. Frontiers in Plant Science 12.
Crossref
Crossref
Keum-Young So, Byung-Hyun Park & Seon-Hee Oh. (2020) Cytoplasmic sirtuin 6 translocation mediated by p62 polyubiquitination plays a critical role in cadmium-induced kidney toxicity. Cell Biology and Toxicology 37:2, pages 193-207.
Crossref
Crossref
Francesco Fiorentino, Vincenzo Carafa, Gregorio Favale, Lucia Altucci, Antonello Mai & Dante Rotili. (2021) The Two-Faced Role of SIRT6 in Cancer. Cancers 13:5, pages 1156.
Crossref
Crossref
Hye-Ran Seo, Daun Jeong, Sunmi Lee, Han-Sae Lee, Shin-Ai Lee, Sang Won Kang & Jongbum Kwon. (2021) CHIP and BAP1 Act in Concert to Regulate INO80 Ubiquitination and Stability for DNA Replication. Molecules and Cells 44:2, pages 101-115.
Crossref
Crossref
Mandy O.J. Grootaert, Alison FiniganNichola L. FiggAnna K. UrygaMartin R. Bennett. (2021) SIRT6 Protects Smooth Muscle Cells From Senescence and Reduces Atherosclerosis. Circulation Research 128:4, pages 474-491.
Crossref
Crossref
Somnath Mazumder, Mukta Barman, Uday Bandyopadhyay & Samik Bindu. (2020) Sirtuins as endogenous regulators of lung fibrosis: A current perspective. Life Sciences 258, pages 118201.
Crossref
Crossref
Mark A. Klein & John M. Denu. (2020) Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators. Journal of Biological Chemistry 295:32, pages 11021-11041.
Crossref
Crossref
Andrew R. Chang, Christina M. Ferrer & Raul Mostoslavsky. (2020) SIRT6, a Mammalian Deacylase with Multitasking Abilities. Physiological Reviews 100:1, pages 145-169.
Crossref
Crossref
Tingyu Wang, Wenbo Wang, Qishan Wang, Rong Xie, Alan Landay & Di Chen. (2019) The E3 ubiquitin ligase CHIP in normal cell function and in disease conditions. Annals of the New York Academy of Sciences 1460:1, pages 3-10.
Crossref
Crossref
Kaiqiang Zhao & Zhongjun Zhou. (2019) Post-translational modifications of nuclear sirtuins. Genome Instability & Disease 1:1, pages 34-45.
Crossref
Crossref
Zheng-wei Hu, Zhi-hua Yang, Shuo Zhang, Yu-tao Liu, Jing Yang, Yan-lin Wang, Cheng-yuan Mao, Qi-meng Zhang, Chang-he Shi & Yu-ming Xu. (2019) Carboxyl Terminus of Hsp70-Interacting Protein Is Increased in Serum and Cerebrospinal Fluid of Patients With Spinocerebellar Ataxia Type 3. Frontiers in Neurology 10.
Crossref
Crossref
Francisco Alejandro Lagunas-Rangel. (2019) Current role of mammalian sirtuins in DNA repair. DNA Repair 80, pages 85-92.
Crossref
Crossref
Shrestha GhoshShrestha Ghosh. 2019. SIRT6 Activities in DNA Damage Repair and Premature Aging. SIRT6 Activities in DNA Damage Repair and Premature Aging
1
59
.
Chang-he Shi, Carrie Rubel, Sarah E. Soss, Rebekah Sanchez-Hodge, Shuo Zhang, Sabrina C. Madrigal, Saranya Ravi, Holly McDonough, Richard C. Page, Walter J. Chazin, Cam Patterson, Cheng-yuan Mao, Monte S. Willis, Hai-Yang Luo, Yu-sheng Li, Donte A. Stevens, Mi-bo Tang, Pan Du, Yao-he Wang, Zheng-wei Hu, Yu-ming Xu & Jonathan C. Schisler. (2018) Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16. PLOS Genetics 14:9, pages e1007664.
Crossref
Crossref
Jae Ho Seo, Ekta Agarwal, Kelly G. Bryant, M. Cecilia Caino, Eui Tae Kim, Andrew V. Kossenkov, Hsin-Yao Tang, Lucia R. Languino, Dmitry I. Gabrilovich, Andrew R. Cohen, David W. Speicher & Dario C. Altieri. (2018) Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements. Cancer Research 78:15, pages 4215-4228.
Crossref
Crossref
Saishruti Kohli, Abhishek Bhardwaj, Richa Kumari & Sanjeev Das. (2018) SIRT6 Is a Target of Regulation by UBE3A That Contributes to Liver Tumorigenesis in an ANXA2-Dependent Manner. Cancer Research 78:3, pages 645-658.
Crossref
Crossref
Z. Çalışkan, T. Mutlu, M. Güven, M. Tunçdemir, M. Niyazioğlu, Y. Hacioglu & Y. Dincer. (2018) SIRT6 expression and oxidative DNA damage in individuals with prediabetes and type 2 diabetes mellitus. Gene 642, pages 542-548.
Crossref
Crossref
Zhaojun Jia, Miao Wang, Shujing Li, Xiahui Li, Xiao-Yan Bai, Zhaowei Xu, Yangyang Yang, Bowen Li, Yanan Li & Huijian Wu. (2018) U-box ubiquitin ligase PPIL2 suppresses breast cancer invasion and metastasis by altering cell morphology and promoting SNAI1 ubiquitination and degradation. Cell Death & Disease 9:2.
Crossref
Crossref
Irene Santos-Barriopedro, Laia Bosch-Presegué, Anna Marazuela-Duque, Carolina de la Torre, Carlota Colomer, Berta N. Vazquez, Thomas Fuhrmann, Bárbara Martínez-Pastor, Wenfu Lu, Thomas Braun, Eva Bober, Thomas Jenuwein, Lourdes Serrano, Manel Esteller, Zhenbang Chen, Silvia Barceló-Batllori, Raúl Mostoslavsky, Lluis Espinosa & Alejandro Vaquero. (2018) SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway. Nature Communications 9:1.
Crossref
Crossref
Sylvana Hassanieh & Raul Mostoslavsky. 2018. Introductory Review on Sirtuins in Biology, Aging, and Disease. Introductory Review on Sirtuins in Biology, Aging, and Disease
117
130
.
Lynn Boyd & Katherine M. Sampuda. 2018. Heat Shock Proteins and Stress. Heat Shock Proteins and Stress
3
11
.
Yannick Kopp, Wei-Han Lang, Tobias B Schuster, Adrián Martínez-Limón, Harald F Hofbauer, Robert Ernst, Giulia Calloni & R Martin Vabulas. (2017) CHIP as a membrane-shuttling proteostasis sensor. eLife 6.
Crossref
Crossref
Kuntal Biswas, Sukumar Sarkar, Kangping Du, David L. Brautigan, Tarek Abbas & James M. Larner. (2017) The E3 Ligase CHIP Mediates p21 Degradation to Maintain Radioresistance. Molecular Cancer Research 15:6, pages 651-659.
Crossref
Crossref
Milena Vitiello, Alberto Zullo, Luigi Servillo, Francesco Paolo Mancini, Adriana Borriello, Alfonso Giovane, Fulvio Della Ragione, Nunzia D’Onofrio & Maria Luisa Balestrieri. (2017) Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases. Ageing Research Reviews 35, pages 301-311.
Crossref
Crossref
Luisa Tasselli, Wei Zheng & Katrin F. Chua. (2017) SIRT6: Novel Mechanisms and Links to Aging and Disease. Trends in Endocrinology & Metabolism 28:3, pages 168-185.
Crossref
Crossref
J Hou, Q Deng, J Zhou, J Zou, Y Zhang, P Tan, W Zhang & H Cui. (2016) CSN6 controls the proliferation and metastasis of glioblastoma by CHIP-mediated degradation of EGFR. Oncogene 36:8, pages 1134-1144.
Crossref
Crossref
Traci L. Parry & Monte S. Willis. (2016) Cardiac ubiquitin ligases: Their role in cardiac metabolism, autophagy, cardioprotection and therapeutic potential. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1862:12, pages 2259-2269.
Crossref
Crossref
Chih-Yang Huang, Wei-Wen Kuo, Jeng-Fan Lo, Tsung-Jung Ho, Pei-ying Pai, Shu-Fen Chiang, Pei-Yu Chen, Fu-Jen Tsai, Chang-Hai Tsai & Chih-Yang Huang. (2016) Doxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death. Cell Death & Disease 7:11, pages e2455-e2455.
Crossref
Crossref
Vibhuti Joshi, Ayeman Amanullah, Arun Upadhyay, Ribhav Mishra, Amit Kumar & Amit Mishra. (2016) A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?. Frontiers in Molecular Neuroscience 9.
Crossref
Crossref
Miaomiao Shao, Lili Li, Shushu Song, Weicheng Wu, Peike Peng, Caiting Yang, Mingming Zhang, Fangfang Duan, Dongwei Jia, Jie Zhang, Hao Wu, Ran Zhao, Lan Wang, Yuanyuan Ruan & Jianxin Gu. (2016) E3 ubiquitin ligase CHIP interacts with C-type lectin-like receptor CLEC-2 and promotes its ubiquitin-proteasome degradation. Cellular Signalling 28:10, pages 1530-1536.
Crossref
Crossref
De-Mao Zhang, Di-Xin Cui, Ruo-Shi Xu, Ya-Chuan Zhou, Li-Wei Zheng, Peng Liu & Xue-Dong Zhou. (2016) Phenotypic research on senile osteoporosis caused by SIRT6 deficiency. International Journal of Oral Science 8:2, pages 84-92.
Crossref
Crossref
Jiaxiang Shao, Xiao Yang, Tengyuan Liu, Tingting Zhang, Qian Reuben Xie & Weiliang Xia. (2016) Autophagy induction by SIRT6 is involved in oxidative stress-induced neuronal damage. Protein & Cell 7:4, pages 281-290.
Crossref
Crossref
Batia Lerrer, Asaf A. Gertler & Haim Y. Cohen. (2016) The complex role of SIRT6 in carcinogenesis. Carcinogenesis 37:2, pages 108-118.
Crossref
Crossref
Bernadette M. M. Zwaans, William Giblin & David B. Lombard. 2016. Sirtuins. Sirtuins
149
170
.
Nikoletta Papaevgeniou & Niki Chondrogianni. 2016. Proteostasis. Proteostasis
1
70
.
Vikram Narayan, Vivien Landré, Jia Ning, Lenka Hernychova, Petr Muller, Chandra Verma, Malcolm D. Walkinshaw, Elizabeth A. Blackburn & Kathryn L. Ball. (2015) Protein–Protein Interactions Modulate the Docking-Dependent E3-Ubiquitin Ligase Activity of Carboxy-Terminus of Hsc70-Interacting Protein (CHIP)*. Molecular & Cellular Proteomics 14:11, pages 2973-2987.
Crossref
Crossref
Dongkai Guo, Zheng Ying, Hongfeng Wang, Dong Chen, Feng Gao, Haigang Ren & Guanghui Wang. (2015) Regulation of autophagic flux by CHIP. Neuroscience Bulletin 31:4, pages 469-479.
Crossref
Crossref
Eui-Jun Kim & Yong-Sung Juhnn. (2015) Cyclic AMP Signaling Reduces Sirtuin 6 Expression in Non-small Cell Lung Cancer Cells by Promoting Ubiquitin-Proteasomal Degradation via Inhibition of the Raf-MEK-ERK (Raf/Mitogen-activated Extracellular Signal-regulated Kinase/Extracellular Signal-regulated Kinase) Pathway. Journal of Biological Chemistry 290:15, pages 9604-9613.
Crossref
Crossref
Adrienne L. Edkins. 2015. The Networking of Chaperones by Co-chaperones. The Networking of Chaperones by Co-chaperones
219
242
.
Sarah M Ronnebaum, Cam Patterson & Jonathan C Schisler. (2014) Emerging evidence of coding mutations in the ubiquitin–proteasome system associated with cerebellar ataxias. Human Genome Variation 1:1.
Crossref
Crossref
Umadevi ThirumurthiJia ShenWeiya XiaAdam M. LaBaffYongkun WeiChia-Wei LiWei-Chao ChangChung-Hsuan ChenHui-Kuan LinDihua YuMien-Chie Hung. (2014) MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer. Science Signaling 7:336.
Crossref
Crossref
Sita Kugel & Raul Mostoslavsky. (2014) Chromatin and beyond: the multitasking roles for SIRT6. Trends in Biochemical Sciences 39:2, pages 72-81.
Crossref
Crossref
Rong Liu, Hua Liu, Yonju Ha, Ronald G. Tilton & Wenbo Zhang. (2014) Oxidative Stress Induces Endothelial Cell Senescence via Downregulation of Sirt6. BioMed Research International 2014, pages 1-13.
Crossref
Crossref
Zhenghong Lin, Heeyoung Yang, Can Tan, Jinping Li, Zhaojian Liu, Qiu Quan, Sinyi Kong, Junsheng Ye, Beixue Gao & Deyu Fang. (2013) USP10 Antagonizes c-Myc Transcriptional Activation through SIRT6 Stabilization to Suppress Tumor Formation. Cell Reports 5:6, pages 1639-1649.
Crossref
Crossref
Catarina Dias, Erisa Nita, Jakub Faktor, Lenka Hernychova, Borivoj Vojtesek, Jesper Nylandsted, Ted R. Hupp, Tilo Kunath & Kathryn Lindsay Ball. (2020) Dominant Steady State Proteome Changes in the Absence of CHIP Highlight a Role in Neuronal Cell Membrane Integrity Linked to the Actin Cytoskeleton. SSRN Electronic Journal.
Crossref
Crossref