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Peter Vandenabeele, Geert Bultynck & Savvas N. Savvides. (2022) Pore-forming proteins as drivers of membrane permeabilization in cell death pathways. Nature Reviews Molecular Cell Biology 24:5, pages 312-333.
Crossref
Crossref
Rebekka Karlowitz & Sjoerd J. L. van Wijk. (2021) Surviving death: emerging concepts of RIPK3 and MLKL ubiquitination in the regulation of necroptosis. The FEBS Journal 290:1, pages 37-54.
Crossref
Crossref
Banita Thakur, Lekha Saha & Alka Bhatia. (2022) Relative refractoriness of breast cancer cells to tumour necrosis factor‐α induced necroptosis. Clinical and Experimental Pharmacology and Physiology 49:12, pages 1294-1306.
Crossref
Crossref
Peixing Wan, Jiong Yan & Zhenggang Liu. (2022) Methodological advances in necroptosis research: From challenges to solutions. Journal of the National Cancer Center 2:4, pages 291-297.
Crossref
Crossref
Csaba Horvath & Georgios Kararigas. (2022) Sex-Dependent Mechanisms of Cell Death Modalities in Cardiovascular Disease. Canadian Journal of Cardiology 38:12, pages 1844-1853.
Crossref
Crossref
Michael J. Morgan & You-Sun Kim. (2022) Roles of RIPK3 in necroptosis, cell signaling, and disease. Experimental & Molecular Medicine 54:10, pages 1695-1704.
Crossref
Crossref
Xinli Hu, Yu Xu, Haojie Zhang, Yao Li, Xiangyang Wang, Cong Xu, Wenfei Ni & Kailiang Zhou. (2022) Role of necroptosis in traumatic brain and spinal cord injuries. Journal of Advanced Research 40, pages 125-134.
Crossref
Crossref
Holly Anderton & Suhaib Alqudah. (2022) Cell death in skin function, inflammation, and disease. Biochemical Journal 479:15, pages 1621-1651.
Crossref
Crossref
Jing Chen, Shiyu Wang, Bart Blokhuis, Rob Ruijtenbeek, Johan Garssen & Frank Redegeld. (2022) Cell Death Triggers Induce MLKL Cleavage in Multiple Myeloma Cells, Which may Promote Cell Death. Frontiers in Oncology 12.
Crossref
Crossref
Xiaoxiao Liu & Li Wan. (2022) Molecular insights into the biochemical functions and signalling mechanisms of plant NLRs. Molecular Plant Pathology 23:6, pages 772-780.
Crossref
Crossref
Carlo Ganini, Manuela Montanaro, Manuel Scimeca, Giampiero Palmieri, Lucia Anemona, Livia Concetti, Gerry Melino, Pierluigi Bove, Ivano Amelio, Eleonora Candi & Alessandro Mauriello. (2022) No Time to Die: How Kidney Cancer Evades Cell Death. International Journal of Molecular Sciences 23:11, pages 6198.
Crossref
Crossref
Izabela Jarabicová, Csaba Horváth, Eva Veľasová, Lenka Bies Piváčková, Jana Vetešková, Ján Klimas, Peter Křenek & Adriana Adameová. (2022) Analysis of necroptosis and its association with pyroptosis in organ damage in experimental pulmonary arterial hypertension. Journal of Cellular and Molecular Medicine 26:9, pages 2633-2645.
Crossref
Crossref
Urbi Mukhopadhyay, Upayan Patra, Pritam Chandra, Priyanka Saha, Animesh Gope, Moumita Dutta & Mamta Chawla‐Sarkar. (2022) Rotavirus activates MLKL‐mediated host cellular necroptosis concomitantly with apoptosis to facilitate dissemination of viral progeny. Molecular Microbiology 117:4, pages 818-836.
Crossref
Crossref
Qi Zhao, Yanbo Zheng, Xing Lv, Jianhua Gong & Lijun Yang. (2021) IMB5036 inhibits human pancreatic cancer growth primarily through activating necroptosis. Basic & Clinical Pharmacology & Toxicology 130:3, pages 375-384.
Crossref
Crossref
Jun Zhuang, Li Xie & Luping Zheng. (2022) A Glimpse of Programmed Cell Death Among Bacteria, Animals, and Plants. Frontiers in Cell and Developmental Biology 9.
Crossref
Crossref
Natália Ketelut-Carneiro & Katherine A. Fitzgerald. (2022) Apoptosis, Pyroptosis, and Necroptosis—Oh My! The Many Ways a Cell Can Die. Journal of Molecular Biology 434:4, pages 167378.
Crossref
Crossref
Mingcheng Liu, Lirong Wang, Xiaojing Xia, Yundi Wu, Chunling Zhu, Mingyuan Duan, Xiaobing Wei, Jianhe Hu & Liancheng Lei. (2021) Regulated lytic cell death in breast cancer. Cell Biology International 46:1, pages 12-33.
Crossref
Crossref
Sabira Mohammed, Nidheesh Thadathil, Ramasamy Selvarani, Evan H. Nicklas, Dawei Wang, Benjamin F. Miller, Arlan Richardson & Sathyaseelan S. Deepa. (2021) Necroptosis contributes to chronic inflammation and fibrosis in aging liver. Aging Cell 20:12.
Crossref
Crossref
Wei LiangWeiwei Qi, Yang GengLinhan Wang, Jing Zhao, Kezhou ZhuGuowei Wu, Zairong ZhangHeling PanLihui QianJunying Yuan. (2021) Necroptosis activates UPR sensors without disrupting their binding with GRP78. Proceedings of the National Academy of Sciences 118:39.
Crossref
Crossref
Milka Koupenova, Heather A. CorkreyOlga VitsevaKahraman TanriverdiMohan Somasundaran, Ping Liu, Shaukat SoofiRohan Bhandari, Matthew GodwinKrishna Mohan Parsi, Alyssa CousineauRené MaehrJennifer P. WangScott J. CameronJeffrey RadeRobert W. FinbergJane E. Freedman. (2021) SARS-CoV-2 Initiates Programmed Cell Death in Platelets. Circulation Research 129:6, pages 631-646.
Crossref
Crossref
Yaqing Yang, Encheng Xie, Lingyu Du, Yu Yang, Bin Wu, Liming Sun, Shuqing Wang & Bo OuYang. (2021) Positive Charges in the Brace Region Facilitate the Membrane Disruption of MLKL-NTR in Necroptosis. Molecules 26:17, pages 5194.
Crossref
Crossref
Justin Taft, Michael Markson, Diana Legarda, Roosheel Patel, Mark Chan, Louise Malle, Ashley Richardson, Conor Gruber, Marta Martín-Fernández, Grazia M.S. Mancini, Jan A.M. van Laar, Philomine van Pelt, Sofija Buta, Beatrijs H.A. Wokke, Ira K.D. Sabli, Vanessa Sancho-Shimizu, Pallavi Pimpale Chavan, Oskar Schnappauf, Raju Khubchandani, Müşerref Kasap Cüceoğlu, Seza Özen, Daniel L. Kastner, Adrian T. Ting, Ivona Aksentijevich, Iris H.I. M. Hollink & Dusan Bogunovic. (2021) Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death. Cell 184:17, pages 4447-4463.e20.
Crossref
Crossref
Kazuhiro Hattori, Naoharu Takano, Hiromi Kazama, Shota Moriya, Keitaro Miyake, Masaki Hiramoto, Kiyoaki Tsukahara & Keisuke Miyazawa. (2021) Induction of synergistic non‑apoptotic cell death by simultaneously targeting proteasomes with bortezomib and histone deacetylase 6 with ricolinostat in head and neck tumor cells. Oncology Letters 22:3.
Crossref
Crossref
Xiaojing Xia, Bin He, Xiulin Zhang, Zhe Cheng, Mingcheng Liu, Xiaobing Wei, Jinqing Jiang & Jianhe Hu. (2021) Lytic regulated cell death in aquaculture fish. Reviews in Aquaculture 13:3, pages 1549-1564.
Crossref
Crossref
Sofie Martens, Jolien Bridelance, Ria Roelandt, Peter Vandenabeele & Nozomi Takahashi. (2021) MLKL in cancer: more than a necroptosis regulator. Cell Death & Differentiation 28:6, pages 1757-1772.
Crossref
Crossref
P.A. Dionísio, J.D. Amaral & C.M.P. Rodrigues. (2021) Oxidative stress and regulated cell death in Parkinson’s disease. Ageing Research Reviews 67, pages 101263.
Crossref
Crossref
Annelise G. Snyder & Andrew Oberst. (2021) The Antisocial Network: Cross Talk Between Cell Death Programs in Host Defense. Annual Review of Immunology 39:1, pages 77-101.
Crossref
Crossref
Lu Li, An Tong, Qiangsheng Zhang, Yuquan Wei & Xiawei Wei. (2021) The molecular mechanisms of MLKL-dependent and MLKL-independent necrosis. Journal of Molecular Cell Biology 13:1, pages 3-14.
Crossref
Crossref
Yanxiang Meng, Jarrod J. Sandow, Peter E. Czabotar & James M. Murphy. (2021) The regulation of necroptosis by post-translational modifications. Cell Death & Differentiation 28:3, pages 861-883.
Crossref
Crossref
André L. Samson, Sarah E. Garnish, Joanne M. Hildebrand & James M. Murphy. (2021) Location, location, location: A compartmentalized view of TNF-induced necroptotic signaling. Science Signaling 14:668.
Crossref
Crossref
Y. Ji, L. A. Ward & C. J. Hawkins. (2021) Reconstitution of Human Necrosome Interactions in Saccharomyces cerevisiae. Biomolecules 11:2, pages 153.
Crossref
Crossref
Stephen J. Beebe, Ravi Joshi, Karl H. Schoenbach & Shu XiaoStephen J. Beebe. 2021. Ultrashort Electric Pulse Effects in Biology and Medicine. Ultrashort Electric Pulse Effects in Biology and Medicine
33
75
.
Larissa C. Zanetti & Ricardo Weinlich. 2021. Ferroptosis: Mechanism and Diseases. Ferroptosis: Mechanism and Diseases
123
138
.
Martin Rübbelke, Dennis Fiegen, Margit Bauer, Florian BinderJames HamiltonJim King, Sven Thamm, Herbert Nar & Markus Zeeb. (2020) Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis. Proceedings of the National Academy of Sciences 117:52, pages 33272-33281.
Crossref
Crossref
Yunseo Woo, Hyo-Ji Lee, Young Mee Jung & Yu-Jin Jung. (2020) Regulated Necrotic Cell Death in Alternative Tumor Therapeutic Strategies. Cells 9:12, pages 2709.
Crossref
Crossref
Hector Flores‐Romero, Uris Ros & Ana J Garcia‐Saez. (2020) Pore formation in regulated cell death. The EMBO Journal 39:23.
Crossref
Crossref
X. Dai, Z. Deng, Y. Liang, L. Chen, W Jiang & W. Zhao. (2020)
Enterococcus faecalis
induces necroptosis in human osteoblastic MG63 cells through the RIPK3 / MLKL signalling pathway
. International Endodontic Journal 53:9, pages 1204-1215.
Crossref
Crossref
Yehui Xiong, Zhifu Han & Jijie Chai. (2020) Resistosome and inflammasome: platforms mediating innate immunity. Current Opinion in Plant Biology 56, pages 47-55.
Crossref
Crossref
Hideki Tanaka, Hirotsugu Hino, Shota Moriya, Hiromi Kazama, Masaya Miyazaki, Naoharu Takano, Masaki Hiramoto, Kiyoaki Tsukahara & Keisuke Miyazawa. (2020) Comparison of autophagy inducibility in various tyrosine kinase inhibitors and their enhanced cytotoxicity via inhibition of autophagy in cancer cells in combined treatment with azithromycin. Biochemistry and Biophysics Reports 22, pages 100750.
Crossref
Crossref
Wenjuan Li, Hengxiao Ni, Shaofeng Wu, Shang Han, Chang'an Chen, Li Li, Yunzhan Li, Fu Gui, Jiahuai Han & Xianming Deng. (2020) Targeting RIPK3 oligomerization blocks necroptosis without inducing apoptosis. FEBS Letters 594:14, pages 2294-2302.
Crossref
Crossref
Xing LiuJudy Lieberman. (2020) Knocking ’em Dead: Pore-Forming Proteins in Immune Defense. Annual Review of Immunology 38:1, pages 455-485.
Crossref
Crossref
Michelle Heib, Stefan Rose-John & Dieter Adam. 2020. Cell Death Regulation In Health And Disease - Part C. Cell Death Regulation In Health And Disease - Part C
83
152
.
Pedro A. Dionísio, Joana D. Amaral & Cecília M.P. Rodrigues. 2020. Cell Death Regulation In Health And Disease - Part C. Cell Death Regulation In Health And Disease - Part C
31
82
.
Archana Shrestha, Iman Mehdizadeh Gohari & Bruce A. McClane. (2019) RIP1, RIP3, and MLKL Contribute to Cell Death Caused by Clostridium perfringens Enterotoxin. mBio 10:6.
Crossref
Crossref
Jing Chen, Renate Kos, Johan Garssen & Frank Redegeld. (2019) Molecular Insights into the Mechanism of Necroptosis: The Necrosome as a Potential Therapeutic Target. Cells 8:12, pages 1486.
Crossref
Crossref
Nupur Bansal, Simone Sciabola & Govinda Bhisetti. (2019) Understanding allosteric interactions in hMLKL protein that modulate necroptosis and its inhibition. Scientific Reports 9:1.
Crossref
Crossref
Cristina D Guibao, Katherine Petrinjak & Tudor Moldoveanu. (2019) Uncovering human mixed lineage kinase domain-like activation in necroptosis. Future Medicinal Chemistry 11:21, pages 2831-2844.
Crossref
Crossref
Paras K. Mishra, Adriana Adameova, Joseph A. Hill, Christopher P. Baines, Peter M. Kang, James M. Downey, Jagat Narula, Masafumi Takahashi, Antonio Abbate, Hande C. Piristine, Sumit Kar, Shi Su, Jason K. Higa, Nicholas K. Kawasaki & Takashi Matsui. (2019) Guidelines for evaluating myocardial cell death. American Journal of Physiology-Heart and Circulatory Physiology 317:5, pages H891-H922.
Crossref
Crossref
Kwang-Ho Lee & Tae-Bong Kang. (2019) The Molecular Links between Cell Death and Inflammasome. Cells 8:9, pages 1057.
Crossref
Crossref
Martin Lichý, Adrián Szobi, Jaroslav Hrdlička, Csaba Horváth, Veronika Kormanová, Tomáš Rajtík, Jan Neckář, František Kolář & Adriana Adameová. (2019) Different signalling in infarcted and non‐infarcted areas of rat failing hearts: A role of necroptosis and inflammation. Journal of Cellular and Molecular Medicine 23:9, pages 6429-6441.
Crossref
Crossref
Lance M Jubic, Svenja Saile, Oliver J Furzer, Farid El Kasmi & Jeffery L Dangl. (2019) Help wanted: helper NLRs and plant immune responses. Current Opinion in Plant Biology 50, pages 82-94.
Crossref
Crossref
Hayden Burdett, Adam R. Bentham, Simon J. Williams, Peter N. Dodds, Peter A. Anderson, Mark J. Banfield & Bostjan Kobe. (2019) The Plant “Resistosome”: Structural Insights into Immune Signaling. Cell Host & Microbe 26:2, pages 193-201.
Crossref
Crossref
Konstantin Bagnjuk & Artur Mayerhofer. (2019) Human Luteinized Granulosa Cells—A Cellular Model for the Human Corpus Luteum. Frontiers in Endocrinology 10.
Crossref
Crossref
A. S. Tkachenko, A. I. Onishchenko, V. G. Gopkalov, T. V. Gorbach, E. A. Kharchenko & D. O. Sklyaruk. (2019) Western Blotting and Flow Cytometry for Evaluating Necroptosis of Cells (Review). Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 4:4, pages 32-37.
Crossref
Crossref
Dan E. McNamara, Cole M. Dovey, Andrew T. Hale, Giovanni Quarato, Christy R. Grace, Cristina D. Guibao, Jonathan Diep, Amanda Nourse, Casey R. Cai, Hong Wu, Ravi C. Kalathur, Douglas R. Green, John D. York, Jan E. Carette & Tudor Moldoveanu. (2019) Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites. Cell Chemical Biology 26:6, pages 863-877.e7.
Crossref
Crossref
Nieves Peltzer & Henning Walczak. (2019) Cell Death and Inflammation – A Vital but Dangerous Liaison. Trends in Immunology 40:5, pages 387-402.
Crossref
Crossref
Caterina Mezzatesta & Beat C. Bornhauser. (2019) Exploiting Necroptosis for Therapy of Acute Lymphoblastic Leukemia. Frontiers in Cell and Developmental Biology 7.
Crossref
Crossref
Konstantin Bagnjuk, Jan Bernd Stöckl, Thomas Fröhlich, Georg Josef Arnold, Rüdiger Behr, Ulrike Berg, Dieter Berg, Lars Kunz, Cecily Bishop, Jing Xu & Artur Mayerhofer. (2019) Necroptosis in primate luteolysis: a role for ceramide. Cell Death Discovery 5:1.
Crossref
Crossref
Mohammad Ali, Linda Roback & Edward S. Mocarski. (2019) Herpes simplex virus 1 ICP6 impedes TNF receptor 1–induced necrosome assembly during compartmentalization to detergent-resistant membrane vesicles. Journal of Biological Chemistry 294:3, pages 991-1004.
Crossref
Crossref
Emma J. Petrie, Peter E. Czabotar & James M. Murphy. (2019) The Structural Basis of Necroptotic Cell Death Signaling. Trends in Biochemical Sciences 44:1, pages 53-63.
Crossref
Crossref
Rafael A. Espiritu, Lohans Pedrera & Uris Ros. 2019.
201
247
.
Xianbo Huang, Feng Xiao, Yuan Li, Wenbin Qian, Wei Ding & Xiujin Ye. (2018) Bypassing drug resistance by triggering necroptosis: recent advances in mechanisms and its therapeutic exploitation in leukemia. Journal of Experimental & Clinical Cancer Research 37:1.
Crossref
Crossref
Zhen Wang, Li-min Guo, Shu-chao Wang, Dan Chen, Jie Yan, Feng-xia Liu, Ju-fang Huang & Kun Xiong. (2018) Progress in studies of necroptosis and its relationship to disease processes. Pathology - Research and Practice 214:11, pages 1749-1757.
Crossref
Crossref
Joseph K. RathkeyJunjie ZhaoZhonghua LiuYinghua Chen, Jie YangHannah C. Kondolf, Bryan L. Benson, Steven M. Chirieleison, Alex Y. Huang, George R. Dubyak, Tsan S. Xiao, Xiaoxia Li & Derek W. Abbott. (2018) Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis. Science Immunology 3:26.
Crossref
Crossref
Hongyan Guo, Ryan P. Gilley, Amanda Fisher, Rebecca Lane, Vanessa J. Landsteiner, Katherine B. Ragan, Cole M. Dovey, Jan E. Carette, Jason W. Upton, Edward S. Mocarski & William J. Kaiser. (2018) Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1. Cell Death & Disease 9:8.
Crossref
Crossref
Jiping Yang, Youyi Zhao, Li Zhang, Hong Fan, Chuchu Qi, Kun Zhang, Xinyu Liu, Lin Fei, Siwei Chen, Mengmeng Wang, Fang Kuang, Yazhou Wang & Shengxi Wu. (2018) RIPK3/MLKL-Mediated Neuronal Necroptosis Modulates the M1/M2 Polarization of Microglia/Macrophages in the Ischemic Cortex. Cerebral Cortex 28:7, pages 2622-2635.
Crossref
Crossref
Emma J. Petrie, Jarrod J. Sandow, Annette V. Jacobsen, Brian J. Smith, Michael D. W. Griffin, Isabelle S. Lucet, Weiwen Dai, Samuel N. Young, Maria C. Tanzer, Ahmad Wardak, Lung-Yu Liang, Angus D. Cowan, Joanne M. Hildebrand, Wilhelmus J. A. Kersten, Guillaume Lessene, John Silke, Peter E. Czabotar, Andrew I. Webb & James M. Murphy. (2018) Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis. Nature Communications 9:1.
Crossref
Crossref
Michael D. Stutz, Samar Ojaimi, Cody Allison, Simon Preston, Philip Arandjelovic, Joanne M. Hildebrand, Jarrod J. Sandow, Andrew I. Webb, John Silke, Warren S. Alexander & Marc Pellegrini. (2017) Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted. Cell Death & Differentiation 25:5, pages 951-965.
Crossref
Crossref
Yu Saito, Shota Moriya, Hiromi Kazama, Kazuhiro Hirasawa, Kana Miyahara, Hiroko Kokuba, Hirotsugu Hino, Hiroyuki Kikuchi, Naoharu Takano, Masaki Hiramoto, Kiyoaki Tsukahara & Keisuke Miyazawa. (2018) Amino acid starvation culture condition sensitizes EGFR-expressing cancer cell lines to gefitinib-mediated cytotoxicity by inducing atypical necroptosis. International Journal of Oncology.
Crossref
Crossref
Kathrin Weber, Ria Roelandt, Inge Bruggeman, Yann Estornes & Peter Vandenabeele. (2018) Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis. Communications Biology 1:1.
Crossref
Crossref
Xuewei Zhang, Kazuyuki Kitatani, Masafumi Toyoshima, Masumi Ishibashi, Toshinori Usui, Junko Minato, Mahy Egiz, Shogo Shigeta, Todd Fox, Tye Deering, Mark Kester & Nobuo Yaegashi. (2018) Ceramide Nanoliposomes as a MLKL-Dependent, Necroptosis-Inducing, Chemotherapeutic Reagent in Ovarian Cancer. Molecular Cancer Therapeutics 17:1, pages 50-59.
Crossref
Crossref
Olga Krysko, Tania Løve Aaes, Valerian E. Kagan, Katharina D'Herde, Claus Bachert, Luc Leybaert, Peter Vandenabeele & Dmitri V. Krysko. (2017) Necroptotic cell death in anti-cancer therapy. Immunological Reviews 280:1, pages 207-219.
Crossref
Crossref
Eduardo Reynoso, Hua Liu, Lin Li, Anthony L. Yuan, She Chen & Zhigao Wang. (2017) Thioredoxin-1 actively maintains the pseudokinase MLKL in a reduced state to suppress disulfide bond-dependent MLKL polymer formation and necroptosis. Journal of Biological Chemistry 292:42, pages 17514-17524.
Crossref
Crossref
Shuzhen LiuHua Liu, Andrea JohnstonSarah Hanna-AddamsEduardo ReynosoYougui XiangZhigao Wang. (2017) MLKL forms disulfide bond-dependent amyloid-like polymers to induce necroptosis. Proceedings of the National Academy of Sciences 114:36.
Crossref
Crossref
Sasker Grootjans, Tom Vanden Berghe & Peter Vandenabeele. (2017) Initiation and execution mechanisms of necroptosis: an overview. Cell Death & Differentiation 24:7, pages 1184-1195.
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