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Molecular and Cellular Biology Volume 27, 2007 - Issue 5
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Article

Dimerization of Protein Tyrosine Phosphatase σ Governs both Ligand Binding and Isoform Specificity

Simon LeeNeural Development Unit, UCL Institute of Child Health, 30 Guilford Street, LondonWC1N 1EH, United Kingdom
,
Clare FauxNeural Development Unit, UCL Institute of Child Health, 30 Guilford Street, LondonWC1N 1EH, United Kingdom
,
Jennifer NixonNeural Development Unit, UCL Institute of Child Health, 30 Guilford Street, LondonWC1N 1EH, United Kingdom
,
Daniel AleteNeural Development Unit, UCL Institute of Child Health, 30 Guilford Street, LondonWC1N 1EH, United Kingdom
,
John ChiltonNeural Development Unit, UCL Institute of Child Health, 30 Guilford Street, LondonWC1N 1EH, United Kingdom
,
Muhamed HawadleNeural Development Unit, UCL Institute of Child Health, 30 Guilford Street, LondonWC1N 1EH, United Kingdom
&
Andrew W. StokerNeural Development Unit, UCL Institute of Child Health, 30 Guilford Street, LondonWC1N 1EH, United KingdomCorrespondence[email protected]
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Pages 1795-1808 | Received 27 Mar 2006, Accepted 25 Nov 2006, Published online: 27 Mar 2023

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Aleixo Muise & Daniela Rotin. (2008) Apical junction complex proteins and ulcerative colitis: a focus on the PTPRS gene. Expert Review of Molecular Diagnostics 8:4, pages 465-477.
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Eisuke Suzuki, Namino Ogawa, Taka-aki Takeda, Yukina Nishito, Yu-ki Tanaka, Takashi Fujiwara, Mayu Matsunaga, Sachiko Ueda, Naoya Kubo, Tokuji Tsuji, Ayako Fukunaka, Tomohiro Yamazaki, Kathryn M. Taylor, Yasumitsu Ogra & Taiho Kambe. (2020) Detailed analyses of the crucial functions of Zn transporter proteins in alkaline phosphatase activation. Journal of Biological Chemistry 295:17, pages 5669-5684.
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Heli Liu. (2019) Synaptic organizers: synaptic adhesion-like molecules (SALMs). Current Opinion in Structural Biology 54, pages 59-67.
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Zhi-Hong Yu & Zhong-Yin Zhang. (2017) Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases. Chemical Reviews 118:3, pages 1069-1091.
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Wiljan Hendriks, Annika Bourgonje, William Leenders & Rafael Pulido. (2018) Proteinaceous Regulators and Inhibitors of Protein Tyrosine Phosphatases. Molecules 23:2, pages 395.
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Zhaohan Lin, Jianmei Liu, Huandi Ding, Fei Xu & Heli Liu. (2018) Structural basis of SALM5-induced PTPδ dimerization for synaptic differentiation. Nature Communications 9:1.
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Chia-Lun Wu, Serge Hardy, Isabelle Aubry, Melissa Landry, Allison Haggarty, Horacio Uri Saragovi & Michel L. Tremblay. (2017) Identification of function-regulating antibodies targeting the receptor protein tyrosine phosphatase sigma ectodomain. PLOS ONE 12:5, pages e0178489.
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Sathyanarayanan Rajagopal, Ishani Deb, Ranjana Poddar & Surojit Paul. (2016) Aging is associated with dimerization and inactivation of the brain-enriched tyrosine phosphatase STEP. Neurobiology of Aging 41, pages 25-38.
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Andrew William Stoker. 2016. Protein Tyrosine Phosphatases. Protein Tyrosine Phosphatases 267 281 .
Ana Lilia Ramírez-Tapia, Lidia Baylón-Pacheco, Patricia Espíritu-Gordillo & José Luis Rosales-Encina. (2015) Characterization of the protein tyrosine phosphatase PRL from Entamoeba histolytica. Experimental Parasitology 159, pages 168-182.
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Samantha N. Hartin, Martin L. Hudson, Curtis Yingling & Brian D. Ackley. (2015) A Synthetic Lethal Screen Identifies a Role for Lin-44/Wnt in C. elegans Embryogenesis. PLOS ONE 10:5, pages e0121397.
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Lalima Gagan AhujaBalasubramanian Gopal. (2014) Bi-Domain Protein Tyrosine Phosphatases Reveal an Evolutionary Adaptation to Optimize Signal Transduction. Antioxidants & Redox Signaling 20:14, pages 2141-2159.
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Jae-Hyuk Yi, Yasuhiro Katagiri, Panpan Yu, Jacob Lourie, Nathanael J. Bangayan, Aviva J. Symes & Herbert M. Geller. (2014) Receptor protein tyrosine phosphatase σ binds to neurons in the adult mouse brain. Experimental Neurology 255, pages 12-18.
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Ryan Murchie, Cong-Hui Guo, Avinash Persaud, Aleixo Muise & Daniela Rotin. (2014) Protein tyrosine phosphatase σ targets apical junction complex proteins in the intestine and regulates epithelial permeability. Proceedings of the National Academy of Sciences 111:2, pages 693-698.
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Shaun-Paul Cordoba, Kaushik Choudhuri, Hao Zhang, Marcus Bridge, Alp Bugra Basat, Michael L. Dustin & P. Anton van der Merwe. (2013) The large ectodomains of CD45 and CD148 regulate their segregation from and inhibition of ligated T-cell receptor. Blood 121:21, pages 4295-4302.
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Pham Ngoc Chien & Seong Eon Ryu. (2012) Protein Tyrosine Phosphatase σ in Proteoglycan-Mediated Neural Regeneration Regulation. Molecular Neurobiology 47:1, pages 220-227.
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Frank Böhmer, Stefan Szedlacsek, Lydia Tabernero, Arne Östman & Jeroen den Hertog. (2013) Protein tyrosine phosphatase structure-function relationships in regulation and pathogenesis. FEBS Journal 280:2, pages 413-431.
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Alma N. Mohebiany, Roman M. Nikolaienko, Samuel Bouyain & Sheila Harroch. (2013) Receptor-type tyrosine phosphatase ligands: looking for the needle in the haystack. FEBS Journal 280:2, pages 388-400.
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Arne Östman, Jeroen Frijhoff, Åsa Sandin & Frank-D. Böhmer. (2011) Regulation of protein tyrosine phosphatases by reversible oxidation. The Journal of Biochemistry 150:4, pages 345-356.
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Vikas V. Dukhande, Devin M. Rogers, Carlos Romá-Mateo, Jordi Donderis, Alberto Marina, Adam O. Taylor, Pascual Sanz & Matthew S. Gentry. (2011) Laforin, a Dual Specificity Phosphatase Involved in Lafora Disease, Is Present Mainly as Monomeric Form with Full Phosphatase Activity. PLoS ONE 6:8, pages e24040.
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Ishani Deb, Ranjana Poddar & Surojit Paul. (2011) Oxidative stress-induced oligomerization inhibits the activity of the non-receptor tyrosine phosphatase STEP61. Journal of Neurochemistry 116:6, pages 1097-1111.
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Jari Heikkinen, Maija Risteli, Outi Lampela, Paula Alavesa, Marjo Karppinen, André H. Juffer & Raili Myllylä. (2011) Dimerization of human lysyl hydroxylase 3 (LH3) is mediated by the amino acids 541–547. Matrix Biology 30:1, pages 27-33.
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Aurnab Ghose & David Van Vactor. 2010. Handbook of Cell Signaling. Handbook of Cell Signaling 737 742 .
Kerstin Hofmeyer & Jessica E. Treisman. (2009) The receptor protein tyrosine phosphatase LAR promotes R7 photoreceptor axon targeting by a phosphatase-independent signaling mechanism. Proceedings of the National Academy of Sciences 106:46, pages 19399-19404.
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Amy E. Hower, Pedro J. Beltran & John L. Bixby. (2009) Dimerization of tyrosine phosphatase PTPRO decreases its activity and ability to inactivate TrkC. Journal of Neurochemistry 110:5, pages 1635-1647.
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Alastair J. Barr, Emilie Ugochukwu, Wen Hwa Lee, Oliver N.F. King, Panagis Filippakopoulos, Ivan Alfano, Pavel Savitsky, Nicola A. Burgess-Brown, Susanne Müller & Stefan Knapp. (2009) Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome. Cell 136:2, pages 352-363.
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Shira Granot-Attas & Ari Elson. (2008) Protein tyrosine phosphatases in osteoclast differentiation, adhesion, and bone resorption. European Journal of Cell Biology 87:8-9, pages 479-490.
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Arnoud Groen, John Overvoorde, Thea van der Wijk & Jeroen den Hertog. (2008) Redox regulation of dimerization of the receptor protein-tyrosine phosphatases RPTPα, LAR, RPTPμ and CD45. FEBS Journal 275:10, pages 2597-2604.
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Wiljan J. A. J. Hendriks, Ari Elson, Sheila Harroch & Andrew W. Stoker. (2008) Protein tyrosine phosphatases: functional inferences from mouse models and human diseases. FEBS Journal 275:5, pages 816-830.
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Jeroen den Hertog, Arne Östman & Frank-D. Böhmer. (2008) Protein tyrosine phosphatases: regulatory mechanisms. FEBS Journal 275:5, pages 831-847.
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Clare Faux, Muhamed Hawadle, Jennifer Nixon, Adam Wallace, Simon Lee, Simon Murray & Andrew Stoker. (2007) PTPσ binds and dephosphorylates neurotrophin receptors and can suppress NGF-dependent neurite outgrowth from sensory neurons. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1773:11, pages 1689-1700.
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Steven C. Almo, Jeffrey B. Bonanno, J. Michael Sauder, Spencer Emtage, Teresa P. Dilorenzo, Vladimir Malashkevich, Steven R. Wasserman, S. Swaminathan, Subramaniam Eswaramoorthy, Rakhi Agarwal, Desigan Kumaran, Mahendra Madegowda, Sugadev Ragumani, Yury Patskovsky, Johnjeff Alvarado, Udupi A. Ramagopal, Joana Faber-Barata, Mark R. Chance, Andrej Sali, Andras Fiser, Zhong-yin Zhang, David S. Lawrence & Stephen K. Burley. (2007) Structural genomics of protein phosphatases. Journal of Structural and Functional Genomics 8:2-3, pages 121-140.
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