Advanced search
Publication Cover
Molecular and Cellular Biology Volume 38, 2018 - Issue 10
Submit an article Journal homepage
105
Views
26
CrossRef citations to date
0
Altmetric
Research Article

Peroxisome Proliferator-Activated Receptor γ and Its Role in Adipocyte Homeostasis and Thiazolidinedione-Mediated Insulin Sensitization

Qiong A. Wanga Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA;b Department of Molecular & Cellular Endocrinology, Diabetes and Metabolism Research Institute, City of Hope/Beckman Research Institute, Duarte, California, USA
,
Fang Zhanga Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA;d Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
,
Lei Jiangb Department of Molecular & Cellular Endocrinology, Diabetes and Metabolism Research Institute, City of Hope/Beckman Research Institute, Duarte, California, USA
,
Risheng Yea Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Yu Ana Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Mengle Shaoa Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Caroline Taoa Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
,
Rana K. Guptaa Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
&
Philipp E. Scherera Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA;c Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0680-3392
ORCID Icon show all
Article: e00677-17 | Received 02 Jan 2018, Accepted 20 Feb 2018, Published online: 03 Mar 2023

Citations (26)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Akshay Sood, Clifford Qualls, Allison Murata, Phillip J. Kroth, Jenny Mao, David S. Schade & Glen Murata. (2023) Potential for repurposing oral hypertension/diabetes drugs to decrease asthma risk in obesity. Journal of Asthma 60:4, pages 802-810.
Read now

Articles from other publishers (25)

Tuoyuan Liu, Ming Yang, Yuping Wu, Guixian Bu, Xingfa Han, Xiaogang Du, Qiuxia Liang, Xiaohan Cao, Anqi Huang, Xianyin Zeng & Fengyan Meng. (2023) PNX14 but not PNX20 as a novel regulator of preadipocyte differentiation via activating Epac-ERK signaling pathway in Gallus gallus. General and Comparative Endocrinology 335, pages 114232.
Crossref
Kyle S. McCommis & Brian N. Finck. (2023) The Hepatic Mitochondrial Pyruvate Carrier as a Regulator of Systemic Metabolism and a Therapeutic Target for Treating Metabolic Disease. Biomolecules 13:2, pages 261.
Crossref
Bosung Kim, Yejin Min, Yongdae Jeong, Sivasubramanian Ramani, Hyewon Lim, Yeonsu Jo, Woosang Kim, Yohan Choi & Sungkwon Park. (2023) Comparison of growth performance and related gene expression of muscle and fat from Landrace, Yorkshire, and Duroc and Woori black pigs. Journal of Animal Science and Technology 65:1, pages 160-174.
Crossref
Ziru Li, Devika P. Bagchi, Junxiong Zhu, Emily Bowers, Hui Yu, Julie Hardij, Hiroyuki Mori, Katrina Granger, Jon Skjaerlund, Gurjit Mandair, Simin Abrishami, Kanakadurga Singer, Kurt D. Hankenson, Clifford J. Rosen & Ormond A. MacDougald. (2022) Constitutive bone marrow adipocytes suppress local bone formation. JCI Insight 7:21.
Crossref
Laia Bertran, Marta Portillo-Carrasquer, Andrea Barrientos-Riosalido, Carmen Aguilar, David Riesco, Salomé Martínez, Amada Culebradas, Margarita Vives, Fàtima Sabench, Daniel Del Castillo, Cristóbal Richart & Teresa Auguet. (2022) Increased Secreted Frizzled-Related Protein 5 mRNA Expression in the Adipose Tissue of Women with Nonalcoholic Fatty Liver Disease Associated with Obesity. International Journal of Molecular Sciences 23:17, pages 9871.
Crossref
Shigeki Nishitani, Atsunori Fukuhara, Issei Tomita, Shinji Kume, Jihoon Shin, Yosuke Okuno, Michio Otsuki, Hiroshi Maegawa & Iichiro Shimomura. (2022) Ketone body 3-hydroxybutyrate enhances adipocyte function. Scientific Reports 12:1.
Crossref
Jan Aaseth, Dragana Javorac, Aleksandra Djordjevic, Zorica Bulat, Anatoly Skalny, Irina Zaitseva, Michael Aschner & Alexey Tinkov. (2022) The Role of Persistent Organic Pollutants in Obesity: A Review of Laboratory and Epidemiological Studies. Toxics 10:2, pages 65.
Crossref
Maria N. Evseeva, Maria S. Balashova, Konstantin Y. Kulebyakin & Yury P. Rubtsov. (2021) Adipocyte Biology from the Perspective of In Vivo Research: Review of Key Transcription Factors. International Journal of Molecular Sciences 23:1, pages 322.
Crossref
Katarzyna Szałabska-Rąpała, Weronika Borymska & Ilona Kaczmarczyk-Sedlak. (2021) Effectiveness of Magnolol, a Lignan from Magnolia Bark, in Diabetes, Its Complications and Comorbidities—A Review. International Journal of Molecular Sciences 22:18, pages 10050.
Crossref
Saeed Alshahrani, Tarique Anwer, Mohammad Firoz Alam, Rayan A. Ahmed, Gyas Khan, Sivagurunathan Moni Sivakumar, Ambreen Shoaib, Prawez Alam & Faizul Azam. (2021) Effect of thymoquinone on high fat diet and STZ‐induced experimental type 2 diabetes: A mechanistic insight by in vivo and in silico studies. Journal of Food Biochemistry 45:8.
Crossref
Dipanjan Guha, Raktim Mukherjee & Palok Aich. (2021) Effects of two potential probiotic Lactobacillus bacteria on adipogenesis in vitro. Life Sciences 278, pages 119538.
Crossref
Alexander Rauch & Susanne Mandrup. (2021) Transcriptional networks controlling stromal cell differentiation. Nature Reviews Molecular Cell Biology 22:7, pages 465-482.
Crossref
Irini Gerges, Margherita Tamplenizza, Federico Martello, Stefano Koman, Giulia Chincarini, Camilla Recordati, Mariacaterina Tamplenizza, Scott Guelcher, Maurizio Crestani & Alessandro Tocchio. (2021) Conditioning the microenvironment for soft tissue regeneration in a cell free scaffold. Scientific Reports 11:1.
Crossref
Seul Gi Lee, Jongbeom Chae, Dong Se Kim, Jung-Bok Lee, Gi-Seok Kwon, Taeg Kyu Kwon & Ju-Ock Nam. (2021) Enhancement of the Antiobesity and Antioxidant Effect of Purple Sweet Potato Extracts and Enhancement of the Effects by Fermentation. Antioxidants 10:6, pages 888.
Crossref
Keiichi Ito, Marc Schneeberger, Alan Gerber, Miki Jishage, Francois Marchildon, Aarthi V. Maganti, Paul Cohen, Jeffrey M. Friedman & Robert G. Roeder. (2021) Critical roles of transcriptional coactivator MED1 in the formation and function of mouse adipose tissues. Genes & Development 35:9-10, pages 729-748.
Crossref
Abhijit Babaji Shinde, Anying Song & Qiong A. Wang. (2021) Brown Adipose Tissue Heterogeneity, Energy Metabolism, and Beyond. Frontiers in Endocrinology 12.
Crossref
Sang Youb Han, Hye Kyoung Song, Jin Joo Cha, Jee Young Han, Young Sun. Kang & Dae Ryong Cha. (2021) Farnesoid X receptor (FXR) agonist ameliorates systemic insulin resistance, dysregulation of lipid metabolism, and alterations of various organs in a type 2 diabetic kidney animal model. Acta Diabetologica 58:4, pages 495-503.
Crossref
Miaozhen Pan, Zhenqi Guan, Peter S. Reinach, Lin Kang, Yuqing Cao, Dengke Zhou, Nethrajeith Srinivasalu, Fei Zhao, Jia Qu & Xiangtian Zhou. (2021) PPARγ modulates refractive development and form deprivation myopia in Guinea pigs. Experimental Eye Research 202, pages 108332.
Crossref
Brooks Taylor, Arnav Shah & Ewa Bielczyk-Maczyńska. (2020) TGF-β is insufficient to induce adipocyte state loss without concurrent PPARγ downregulation. Scientific Reports 10:1.
Crossref
Lucy V Trevor, Kirsten Riches-Suman, Ajay L Mahajan & M Julie Thornton. (2020) Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing. Journal of Clinical Medicine 9:7, pages 2161.
Crossref
Anne Fougerat, Alexandra Montagner, Nicolas Loiseau, Hervé Guillou & Walter Wahli. (2020) Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease. Cells 9:7, pages 1638.
Crossref
Luana A. Biondo, Alexandre A. S. Teixeira, Karen C. de O. S. Ferreira & Jose C. R. Neto. (2020) Pharmacological Strategies for Insulin Sensitivity in Obesity and Cancer: Thiazolidinediones and Metformin. Current Pharmaceutical Design 26:9, pages 932-945.
Crossref
Fatemeh Khatami, Mohammad R. Mohajeri-Tehrani & Seyed M. Tavangar. (2019) The Importance of Precision Medicine in Type 2 Diabetes Mellitus (T2DM): From Pharmacogenetic and Pharmacoepigenetic Aspects. Endocrine, Metabolic & Immune Disorders - Drug Targets 19:6, pages 719-731.
Crossref
Rachel K. Zwick, Michael C. Rudolph, Brett A. Shook, Brandon Holtrup, Eve Roth, Vivian Lei, Alexandra Van Keymeulen, Victoria Seewaldt, Stephanie Kwei, John Wysolmerski, Matthew S. Rodeheffer & Valerie Horsley. (2018) Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation. Nature Communications 9:1.
Crossref
Xinran Ma, Dongmei Wang, Wenjun Zhao & Lingyan Xu. (2018) Deciphering the Roles of PPARγ in Adipocytes via Dynamic Change of Transcription Complex. Frontiers in Endocrinology 9.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.