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Molecular and Cellular Biology Volume 34, 2014 - Issue 21
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Article

Release Factor eRF3 Mediates Premature Translation Termination on Polylysine-Stalled Ribosomes in Saccharomyces cerevisiae

Marco Chiabudinia Institute of Biochemistry and Molecular Biology, ZBMZ, University of Freiburg, Freiburg, Germany;b Center for Biological Signaling Studies (BIOSS), University of Freiburg, Freiburg, Germany
,
Arlette Taisa Institute of Biochemistry and Molecular Biology, ZBMZ, University of Freiburg, Freiburg, Germany
,
Ying Zhanga Institute of Biochemistry and Molecular Biology, ZBMZ, University of Freiburg, Freiburg, Germany
,
Sachiko Hayashia Institute of Biochemistry and Molecular Biology, ZBMZ, University of Freiburg, Freiburg, Germany
,
Tina Wölflea Institute of Biochemistry and Molecular Biology, ZBMZ, University of Freiburg, Freiburg, Germany
,
Edith Fitzkea Institute of Biochemistry and Molecular Biology, ZBMZ, University of Freiburg, Freiburg, Germany
&
Sabine Rosperta Institute of Biochemistry and Molecular Biology, ZBMZ, University of Freiburg, Freiburg, Germany;b Center for Biological Signaling Studies (BIOSS), University of Freiburg, Freiburg, GermanyCorrespondence[email protected]
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Pages 4062-4076 | Received 11 Jun 2014, Accepted 19 Aug 2014, Published online: 20 Mar 2023

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Kerstin Schmitt, Nadine Smolinski, Piotr Neumann, Samantha Schmaul, Verena Hofer-Pretz, Gerhard H. Braus & Oliver Valerius. (2017) Asc1p/RACK1 Connects Ribosomes to Eukaryotic Phosphosignaling. Molecular and Cellular Biology 37:3.
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Rodrigo D. Requião, Henrique José Araujo de Souza, Silvana Rossetto, Tatiana Domitrovic & Fernando L. Palhano. (2016) Increased ribosome density associated to positively charged residues is evident in ribosome profiling experiments performed in the absence of translation inhibitors. RNA Biology 13:6, pages 561-568.
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Simone Gallo & Nicola Manfrini. (2015) Working hard at the nexus between cell signaling and the ribosomal machinery: An insight into the roles of RACK1 in translational regulation. Translation 3:2.
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Tyler J. Smith, Mehmet Tardu, Hem Raj Khatri & Kristin S. Koutmou. (2022) mRNA and tRNA modification states influence ribosome speed and frame maintenance during poly(lysine) peptide synthesis. Journal of Biological Chemistry 298:6, pages 102039.
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Qian Yang, Chien-Hung Yu, Fangzhou Zhao, Yunkun Dang, Cheng Wu, Pancheng Xie, Matthew S Sachs & Yi Liu. (2019) eRF1 mediates codon usage effects on mRNA translation efficiency through premature termination at rare codons. Nucleic Acids Research 47:17, pages 9243-9258.
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Anne-Sophie Gribling-Burrer, Marco Chiabudini, Ying Zhang, Zonghao Qiu, Mario Scazzari, Tina Wölfle, Daniel Wohlwend & Sabine Rospert. (2019) A dual role of the ribosome-bound chaperones RAC/Ssb in maintaining the fidelity of translation termination. Nucleic Acids Research 47:13, pages 7018-7034.
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Miki Wada & Koichi Ito. (2018) Misdecoding of rare CGA codon by translation termination factors, eRF1/eRF3, suggests novel class of ribosome rescue pathway in S. cerevisiae . The FEBS Journal 286:4, pages 788-802.
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Kevin C. Stein & Judith Frydman. (2019) The stop-and-go traffic regulating protein biogenesis: How translation kinetics controls proteostasis. Journal of Biological Chemistry 294:6, pages 2076-2084.
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Anthony Khong & Roy Parker. (2018) mRNP architecture in translating and stress conditions reveals an ordered pathway of mRNP compaction. Journal of Cell Biology 217:12, pages 4124-4140.
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Kaivalya Mudholkar, Edith Fitzke, Claudia Prinz, Matthias P. Mayer & Sabine Rospert. (2017) The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway. Nature Communications 8:1.
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Claudio A.P. Joazeiro. (2017) Ribosomal Stalling During Translation: Providing Substrates for Ribosome-Associated Protein Quality Control. Annual Review of Cell and Developmental Biology 33:1, pages 343-368.
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Ying Zhang, Irmgard Sinning & Sabine Rospert. (2017) Two chaperones locked in an embrace: structure and function of the ribosome-associated complex RAC. Nature Structural & Molecular Biology 24:8, pages 611-619.
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Nur H. Jamar, Paraskevi Kritsiligkou & Chris M. Grant. (2017) The non-stop decay mRNA surveillance pathway is required for oxidative stress tolerance. Nucleic Acids Research 45:11, pages 6881-6893.
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Cole S. Sitron, Joseph H. Park & Onn Brandman. (2017) Asc1, Hel2, and Slh1 couple translation arrest to nascent chain degradation. RNA 23:5, pages 798-810.
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Szymon Juszkiewicz & Ramanujan S. Hegde. (2017) Initiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome Ubiquitination. Molecular Cell 65:4, pages 743-750.e4.
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Yury O. Chernoff & Denis A. Kiktev. (2016) Dual role of ribosome-associated chaperones in prion formation and propagation. Current Genetics 62:4, pages 677-685.
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Claire Roulston, Garry A. Luke, Pablo Felipe, Lin Ruan, Jonathan Cope, John Nicholson, Andriy Sukhodub, Jens Tilsner & Martin D. Ryan. (2016) ‘ 2A ‐Like’ Signal Sequences Mediating Translational Recoding: A Novel Form of Dual Protein Targeting . Traffic 17:8, pages 923-939.
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Alexander Belyy, Nadezhda Levanova, Irina Tabakova, Sabine Rospert & Yury Belyi. (2016) Ribosomal Protein Rps26 Influences 80S Ribosome Assembly in Saccharomyces cerevisiae. mSphere 1:1.
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Kristin S Koutmou, Anthony P Schuller, Julie L Brunelle, Aditya Radhakrishnan, Sergej Djuranovic & Rachel Green. (2015) Ribosomes slide on lysine-encoding homopolymeric A stretches. eLife 4.
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Sichen Shao, Alan Brown, Balaji Santhanam & Ramanujan S. Hegde. (2015) Structure and Assembly Pathway of the Ribosome Quality Control Complex. Molecular Cell 57:3, pages 433-444.
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