Advanced search
Publication Cover
Molecular and Cellular Biology Volume 31, 2011 - Issue 7
Submit an article Journal homepage
54
Views
39
CrossRef citations to date
0
Altmetric
Article

Inhibitory Phosphorylation of Cyclin-Dependent Kinase 1 as a Compensatory Mechanism for Mitosis Exit

Jeremy P. H. ChowDivision of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong
,
Randy Y. C. PoonDivision of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Hong KongCorrespondence[email protected]
&
Hoi Tang MaDivision of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong
Pages 1478-1491 | Received 31 Jul 2010, Accepted 16 Jan 2011, Published online: 20 Mar 2023

Citations (39)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Wing Ki Wong, Terrenz Kelly, Jingjing Li, Hoi Tang Ma & Randy YC Poon. (2015) SGO1C is a non-functional isoform of Shugoshin and can disrupt sister chromatid cohesion by interacting with PP2A–B56. Cell Cycle 14:24, pages 3965-3977.
Read now
Paola Vagnarelli & William C. Earnshaw. (2012) Repo-Man-PP1. Nucleus 3:2, pages 138-142.
Read now
Ralph Wäsch. (2011) Targeting mitotic exit for cancer treatment. Expert Opinion on Therapeutic Targets 15:7, pages 785-788.
Read now

Articles from other publishers (36)

Chunhui Zhou, Sujuan Zhu & Haiping Li. (2023) miR-195-5p Targets CDK1 To Regulate New DNA Synthesis and Inhibit the Proliferation of Hepatocellular Carcinoma Cells. Applied Biochemistry and Biotechnology 195:5, pages 3477-3490.
Crossref
Shuang Wang, Ximeng Liu, Ting Zhou, Jinling Li, Ying Lin, Anni Zhou, Jiamin Huang, Jingjing Zhao, Junchao Cai, Xiuyu Cai, Yongbo Huang & Xu Li. (2022) PKMYT1 inhibits lung adenocarcinoma progression by abrogating AKT1 activity. Cellular Oncology 46:1, pages 195-209.
Crossref
Akito Koike, Frank Becker, Peter Sennhenn, Jason Kim, Jenny Zhang, Stefan Hannus & Klaus Brehm. (2022) Targeting Echinococcus multilocularis PIM kinase for improving anti-parasitic chemotherapy. PLOS Neglected Tropical Diseases 16:10, pages e0010483.
Crossref
Radka Michalkova, Martin Kello, Zuzana Kudlickova, Maria Gazdova, Ladislav Mirossay, Gabriela Mojzisova & Jan Mojzis. (2022) Programmed Cell Death Alterations Mediated by Synthetic Indole Chalcone Resulted in Cell Cycle Arrest, DNA Damage, Apoptosis and Signaling Pathway Modulations in Breast Cancer Model. Pharmaceutics 14:3, pages 503.
Crossref
Endah Endah, Febri Wulandari, Yurananda Putri, Riris Istighfari Jenie & Edy Meiyanto. (2022) Piperine Increases Pentagamavunon-1 Anti-cancer Activity on 4T1 Breast Cancer Through Mitotic Catastrophe Mechanism and Senescence with Sharing Targeting on Mitotic Regulatory Proteins. Iranian Journal of Pharmaceutical Research 21:1.
Crossref
Pengyan Fa, Zhaojun Qiu, Qi-En Wang, Chunhong Yan & Junran Zhang. (2022) A Novel Role for RNF126 in the Promotion of G2 Arrest via Interaction With 14-3-3σ. International Journal of Radiation Oncology*Biology*Physics 112:2, pages 542-553.
Crossref
Ruma Pal-Ghosh, Danfeng Xue, Rod Warburton, Nicholas Hill, Peter Polgar & Jamie L. Wilson. (2021) CDC2 Is an Important Driver of Vascular Smooth Muscle Cell Proliferation via FOXM1 and PLK1 in Pulmonary Arterial Hypertension. International Journal of Molecular Sciences 22:13, pages 6943.
Crossref
Andrea Ghelli Luserna di Rorà, Claudio Cerchione, Giovanni Martinelli & Giorgia Simonetti. (2020) A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target. Journal of Hematology & Oncology 13:1.
Crossref
Ashraf A. Aly, Stefan Bräse, Alaa A. Hassan, Nasr K. Mohamed, Lamiaa E. Abd El-Haleem, Martin Nieger, Nesrin M. Morsy, Mohammed B. Alshammari, Mahmoud A. A. Ibrahim & Elshimaa M. N. Abdelhafez. (2020) Design, Synthesis, and Molecular Docking of Paracyclophanyl-Thiazole Hybrids as Novel CDK1 Inhibitors and Apoptosis Inducing Anti-Melanoma Agents. Molecules 25:23, pages 5569.
Crossref
Naira Movsisyan & Luis A. Pardo. (2020) Kv10.1 Regulates Microtubule Dynamics during Mitosis. Cancers 12:9, pages 2409.
Crossref
Qili Fei, Zhongyu Zou, Ian A. Roundtree, Hui-Lung Sun & Chuan He. (2020) YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators. PLOS Biology 18:4, pages e3000664.
Crossref
Tsun Ming Lok, Yang Wang, Wendy Kaichun Xu, Siwei Xie, Hoi Tang Ma & Randy Y. C. Poon. (2020) Mitotic slippage is determined by p31comet and the weakening of the spindle-assembly checkpoint. Oncogene 39:13, pages 2819-2834.
Crossref
Cody W. Lewis, Amirali B. Bukhari, Edric J. Xiao, Won-Shik Choi, Joanne D. Smith, Ellen Homola, John R. Mackey, Shelagh D. Campbell, Armin M. Gamper & Gordon K. Chan. (2019) Upregulation of Myt1 Promotes Acquired Resistance of Cancer Cells to Wee1 Inhibition. Cancer Research 79:23, pages 5971-5985.
Crossref
Amirali B. Bukhari, Cody W. Lewis, Joanna J. Pearce, Deandra Luong, Gordon K. Chan & Armin M. Gamper. (2019) Inhibiting Wee1 and ATR kinases produces tumor-selective synthetic lethality and suppresses metastasis. Journal of Clinical Investigation 129:3, pages 1329-1344.
Crossref
Shengnan Du, Jeffrey G. Sarver, Christopher J. Trabbic, Paul W. Erhardt, Allen Schroering & William A. Maltese. (2018) 6-MOMIPP, a novel brain-penetrant anti-mitotic indolyl-chalcone, inhibits glioblastoma growth and viability. Cancer Chemotherapy and Pharmacology 83:2, pages 237-254.
Crossref
Maria Horiuchi, Takahisa Kuga, Youhei Saito, Maiko Nagano, Jun Adachi, Takeshi Tomonaga, Naoto Yamaguchi & Yuji Nakayama. (2018) The tyrosine kinase v-Src causes mitotic slippage by phosphorylating an inhibitory tyrosine residue of Cdk1. Journal of Biological Chemistry 293:40, pages 15524-15537.
Crossref
Hongwei Liao, Fang Ji, Xinwei Geng, Meichun Xing, Wen Li, Zhihua Chen, Huahao Shen & Songmin Ying. (2017) CDK1 promotes nascent DNA synthesis and induces resistance of cancer cells to DNA-damaging therapeutic agents. Oncotarget 8:53, pages 90662-90673.
Crossref
Cody W. Lewis, Zhigang Jin, Dawn Macdonald, Wenya Wei, Xu Jing Qian, Won Shik Choi, Ruicen He, Xuejun Sun & Gordon Chan. (2017) Prolonged mitotic arrest induced by Wee1 inhibition sensitizes breast cancer cells to paclitaxel. Oncotarget 8:43, pages 73705-73722.
Crossref
Christina Gutierrez Bracamontes, Rebecca Lopez-Valdez, Ramadevi Subramani, Arunkumar Arumugam, Sushmita Nandy, Venkatesh Rajamanickam, Vignesh Ravichandran & Rajkumar Lakshmanaswamy. (2016) The serum protein profile of early parity which induces protection against breast cancer. Oncotarget 7:50, pages 82538-82553.
Crossref
Agnieszka Żuryń, Adrian Krajewski, Dawid Szulc, Anna Litwiniec & Alina Grzanka. (2016) Activity of cyclin B1 in HL-60 cells treated with etoposide. Acta Histochemica 118:5, pages 537-543.
Crossref
Barbara Bukowska, Aneta Rogalska, Ewa Forma, Magdalena Brys & Agnieszka Marczak. (2016) Why a Combination of WP 631 and Epo B is an Improvement on the Drugs Singly - Involvement in the Cell Cycle and Mitotic Slippage. Asian Pacific Journal of Cancer Prevention 17:3, pages 1299-1308.
Crossref
Amber L. Lasek, Brittany M. McPherson, Natalie G. Trueman & Mark E. Burkard. (2016) The Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic Complementation. PLOS ONE 11:2, pages e0150225.
Crossref
Tatiana V. Denisenko, Irina V. Sorokina, Vladimir Gogvadze & Boris Zhivotovsky. (2016) Mitotic catastrophe and cancer drug resistance: A link that must to be broken. Drug Resistance Updates 24, pages 1-12.
Crossref
Anne Margriet HeijinkVincent A. BlomenXavier BisteauFabian DegenerFelipe Yu MatsushitaPhilipp Kaldis, Floris Foijer & Marcel A. T. M. van Vugt. (2015) A haploid genetic screen identifies the G 1 /S regulatory machinery as a determinant of Wee1 inhibitor sensitivity . Proceedings of the National Academy of Sciences 112:49, pages 15160-15165.
Crossref
Erik Voets & Rob Wolthuis. (2015) MASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C. Biology Open 4:4, pages 484-495.
Crossref
Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. LoughranJr.Jr., Mark Kester, Hong-Gang Wang & Jong K. Yun. (2015) The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines. Journal of Pharmacology and Experimental Therapeutics 352:3, pages 494-508.
Crossref
Joyce P.Y. Mak, Wing Yu Man, Hoi Tang Ma & Randy Y.C. Poon. (2014) Pharmacological targeting the ATR-CHK1–WEE1 axis involves balancing cell growth stimulation and apoptosis. Oncotarget 5:21, pages 10546-10557.
Crossref
Eleni Petsalaki & George Zachos. (2014) Chk2 prevents mitotic exit when the majority of kinetochores are unattached. Journal of Cell Biology 205:3, pages 339-356.
Crossref
Sergiy A Starosyla. (2014) Pharmacophore approaches in protein kinase inhibitors design. World Journal of Pharmacology 3:4, pages 162.
Crossref
Joseph O Ayeni, Ramya Varadarajan, Oindrila Mukherjee, David T Stuart, Frank Sprenger, Martin Srayko & Shelagh D Campbell. (2014) Dual Phosphorylation of Cdk1 Coordinates Cell Proliferation with Key Developmental Processes in Drosophila . Genetics 196:1, pages 197-210.
Crossref
J P H Chow & R Y C Poon. (2012) The CDK1 inhibitory kinase MYT1 in DNA damage checkpoint recovery. Oncogene 32:40, pages 4778-4788.
Crossref
Hyoeun Kang, Seok Cheol Hwang, Yong Seok Park & Jeong Su Oh. (2013) Cdc25B phosphatase participates in maintaining metaphase II arrest in mouse oocytes. Molecules and Cells 35:6, pages 514-518.
Crossref
Jeong Su Oh, Andrej Susor, Karen Schindler, Richard M. Schultz & Marco Conti. (2013) Cdc25A activity is required for the metaphase II arrest in mouse oocytes. Journal of Cell Science 126:5, pages 1081-1085.
Crossref
Barbara Fasulo, Carol Koyama, Kristina R. Yu, Ellen M. Homola, Tao S. Hsieh, Shelagh D. Campbell & William Sullivan. (2012) Chk1 and Wee1 kinases coordinate DNA replication, chromosome condensation, and anaphase entry. Molecular Biology of the Cell 23:6, pages 1047-1057.
Crossref
Y.-J. Shi & K.-K. Huo. (2012) Knockdown expression of Apc11 leads to cell-cycle distribution reduction in G2/M phase. Genetics and Molecular Research 11:3, pages 2814-2822.
Crossref
Jonathon Pines. (2011) Cubism and the cell cycle: the many faces of the APC/C. Nature Reviews Molecular Cell Biology 12:7, pages 427-438.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.