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Article

Neph1 Cooperates with Nephrin To Transduce a Signal That Induces Actin Polymerization

Puneet Garg1 Division of Nephrology, University of Michigan Medical School, Ann Arbor, Michigan48109
,
Rakesh Verma1 Division of Nephrology, University of Michigan Medical School, Ann Arbor, Michigan48109
,
Deepak Nihalani3 Division of Nephrology, Indiana University School of Medicine, Indianapolis, Indiana46202
,
Duncan B. Johnstone1 Division of Nephrology, University of Michigan Medical School, Ann Arbor, Michigan48109
&
Lawrence B. Holzman1 Division of Nephrology, University of Michigan Medical School, Ann Arbor, Michigan48109;2 Department of Veterans Affairs, Ann Arbor, Michigan48105Correspondence[email protected]
Pages 8698-8712 | Received 29 May 2007, Accepted 28 Sep 2007, Published online: 27 Mar 2023

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Ehtesham Arif, Pankaj Sharma, Ashish Solanki, Leena Mallik, Yogendra S. Rathore, Waleed O. Twal, Samir K. Nath, Darpan Gandhi, Lawrence B. Holzman, E. Michael Ostap, Ashish & Deepak Nihalani. (2016) Structural Analysis of the Myo1c and Neph1 Complex Provides Insight into the Intracellular Movement of Neph1. Molecular and Cellular Biology 36:11, pages 1639-1654.
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Ivan M. Blasutig, Laura A. New, Ajitha Thanabalasuriar, Thamara K. Dayarathna, Marilyn Goudreault, Susan E. Quaggin, Shawn S.-C. Li, Samantha Gruenheid, Nina Jones & Tony Pawson. (2008) Phosphorylated YDXV Motifs and Nck SH2/SH3 Adaptors Act Cooperatively To Induce Actin Reorganization. Molecular and Cellular Biology 28:6, pages 2035-2046.
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Samuel Mon-Wei Yu, Pitchaphon Nissaisorakarn, Irma Husain & Belinda Jim. (2018) Proteinuric Kidney Diseases: A Podocyte's Slit Diaphragm and Cytoskeleton Approach. Frontiers in Medicine 5.
Crossref
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Crossref
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Crossref
Henning Hagmann & Paul T. Brinkkoetter. (2018) Experimental Models to Study Podocyte Biology: Stock-Taking the Toolbox of Glomerular Research. Frontiers in Pediatrics 6.
Crossref
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Crossref
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Crossref
Sascha Gromnitza, Carolin Lepa, Thomas Weide, Albrecht Schwab, Hermann Pavenstädt & Britta George. (2018) Tropomyosin‐related kinase C (TrkC) enhances podocyte migration by ERK‐mediated WAVE2 activation. The FASEB Journal 32:3, pages 1665-1676.
Crossref
Claire E. Martin, Kelly A. Petersen, Lamine Aoudjit, Manali Tilak, Vera Eremina, W. Rod Hardy, Susan E. Quaggin, Tomoko Takano & Nina Jones. (2018) ShcA Adaptor Protein Promotes Nephrin Endocytosis and Is Upregulated in Proteinuric Nephropathies. Journal of the American Society of Nephrology 29:1, pages 92-103.
Crossref
Bangli Hu, Cheng Shi, Hai-xing Jiang & Shan-yu Qin. (2017) Identification of novel therapeutic target genes and pathway in pancreatic cancer by integrative analysis. Medicine 96:42, pages e8261.
Crossref
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Crossref
Jamie S. Lin, Jin Seok Jeon, Qingfeng Fan, Hetty N. Wong, Matthew B. Palmer & Lawrence B. Holzman. (2017) ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics. PLOS ONE 12:9, pages e0184575.
Crossref
Nicole Endlich, Florian Siegerist & Karlhans Endlich. (2017) Are podocytes motile?. Pflügers Archiv - European Journal of Physiology 469:7-8, pages 951-957.
Crossref
Agnieszka Swiatecka-Urban. (2017) Endocytic Trafficking at the Mature Podocyte Slit Diaphragm. Frontiers in Pediatrics 5.
Crossref
Luca Perico, Sara Conti, Ariela Benigni & Giuseppe Remuzzi. (2016) Podocyte–actin dynamics in health and disease. Nature Reviews Nephrology 12:11, pages 692-710.
Crossref
Rodrigo Villarreal, Alla Mitrofanova, Dony Maiguel, Ximena Morales, Jongmin Jeon, Florian Grahammer, Ingo B. Leibiger, Johanna Guzman, Alberto Fachado, Tae H. Yoo, Anja Busher Katin, Jutta Gellermann, Sandra Merscher, George W. Burke, Per-Olof Berggren, Jun Oh, Tobias B. Huber & Alessia Fornoni. (2016) Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor. Journal of the American Society of Nephrology 27:4, pages 1029-1041.
Crossref
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Crossref
Jochen Reiser & Mehmet M. Altintas. (2016) Podocytes. F1000Research 5, pages 114.
Crossref
Markus M. Rinschen, Thomas Benzing, Kavee Limbutara & Trairak Pisitkun. (2015) Proteomic analysis of the kidney filtration barrier-Problems and perspectives. PROTEOMICS - Clinical Applications 9:11-12, pages 1053-1068.
Crossref
Burcak Yesildag, Thomas Bock, Karolin Herrmanns, Bernd Wollscheid & Markus Stoffel. (2015) Kin of IRRE-like Protein 2 Is a Phosphorylated Glycoprotein That Regulates Basal Insulin Secretion. Journal of Biological Chemistry 290:43, pages 25891-25906.
Crossref
Merja Joensuu & Eija Jokitalo. (2015) ER sheet–tubule balance is regulated by an array of actin filaments and microtubules. Experimental Cell Research 337:2, pages 170-178.
Crossref
Maija Suvanto, Timo Jahnukainen, Marjo Kestilä & Hannu Jalanko. (2014) Podocyte proteins in congenital and minimal change nephrotic syndrome. Clinical and Experimental Nephrology 19:3, pages 481-488.
Crossref
Markus M. Rinschen, Caroline Pahmeyer, Trairak Pisitkun, Nicole Schnell, Xiongwu Wu, Martina Maaß, Malte P. Bartram, Tobias Lamkemeyer, Bernhard Schermer, Thomas Benzing & Paul T. Brinkkoetter. (2015) Comparative phosphoproteomic analysis of mammalian glomeruli reveals conserved podocin C-terminal phosphorylation as a determinant of slit diaphragm complex architecture. PROTEOMICS 15:7, pages 1326-1331.
Crossref
Oleh Akchurin & Kimberly J. Reidy. (2014) Genetic causes of proteinuria and nephrotic syndrome: Impact on podocyte pathobiology. Pediatric Nephrology 30:2, pages 221-233.
Crossref
Katerina Kapodistria, Effie-Photini Tsilibary, Panagiotis Politis, Petros Moustardas, Aristidis Charonis & Paraskevi Kitsiou. (2015) Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling. Molecular and Cellular Endocrinology 400, pages 112-128.
Crossref
Rachel Lennon, Michael J. Randles & Martin J. Humphries. (2014) The Importance of Podocyte Adhesion for a Healthy Glomerulus. Frontiers in Endocrinology 5.
Crossref
Jenny Hulkko, Jaakko Patrakka, Mark Lal, Karl Tryggvason, Kjell Hultenby & Annika Wernerson. (2014) Neph1 Is Reduced in Primary Focal Segmental Glomerulosclerosis, Minimal Change Nephrotic Syndrome, and Corresponding Experimental Animal Models of Adriamycin-Induced Nephropathy and Puromycin Aminonucleoside Nephrosis. Nephron Extra 4:3, pages 146-154.
Crossref
Laura A. New, Claire E. Martin & Nina Jones. (2014) Advances in slit diaphragm signaling. Current Opinion in Nephrology and Hypertension 23:4, pages 420-430.
Crossref
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Crossref
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Crossref
Mervi Ristola & Sanna Lehtonen. (2013) Functions of the podocyte proteins nephrin and Neph3 and the transcriptional regulation of their genes. Clinical Science 126:5, pages 315-328.
Crossref
Antonio S. TutorSilvia Prieto-SánchezMar Ruiz-Gómez. (2014) Src64B phosphorylates Dumbfounded and regulates slit diaphragm dynamics: Drosophila as a model to study nephropathies . Development 141:2, pages 367-376.
Crossref
Baoyu Chen, Klaus Brinkmann, Zhucheng Chen, Chi W. Pak, Yuxing Liao, Shuoyong Shi, Lisa Henry, Nick V. Grishin, Sven Bogdan & Michael K. Rosen. (2014) The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton. Cell 156:1-2, pages 195-207.
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Crossref
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Crossref
Satoshi TakahashiMai TomiokaKeiju HiromuraToru SakairiHiroko HamataniMitsuharu WatanabeHidekazu IkeuchiYoriaki KanekoAkito MaeshimaTakeo AokiHiroshi OhnishiTakashi Matozaki & Yoshihisa Nojima. (2013) SIRPα signaling regulates podocyte structure and function. American Journal of Physiology-Renal Physiology 305:6, pages F861-F870.
Crossref
Peter J. DurcanNasser Al-ShantiClaire E. Stewart. (2013) Identification and characterization of novel Kirrel isoform during myogenesis. Physiological Reports 1:3.
Crossref
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Crossref
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Crossref
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Crossref
Lisa M. Bond, Hemma Brandstaetter, John Kendrick-Jones & Folma Buss. (2013) Functional roles for myosin 1c in cellular signaling pathways. Cellular Signalling 25:1, pages 229-235.
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Crossref
Yuko Kajiho, Yutaka Harita, Hidetake Kurihara, Shigeru Horita, Atsuko Matsunaga, Haruko Tsurumi, Shoichiro Kanda, Noriko Sugawara, Kenichiro Miura, Takashi Sekine, Seisuke Hattori, Motoshi Hattori & Takashi Igarashi. (2012) SIRP α interacts with nephrin at the podocyte slit diaphragm . FEBS Journal 279:17, pages 3010-3021.
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Puneet Garg & Lawrence B. Holzman. (2012) Podocytes: Gaining a foothold. Experimental Cell Research 318:9, pages 955-963.
Crossref
Anna GrekaPeter Mundel. (2012) Cell Biology and Pathology of Podocytes. Annual Review of Physiology 74:1, pages 299-323.
Crossref
Leena Mallik, Ehtesham Arif, Pankaj Sharma, Yogendra S. Rathore, Hetty N. Wong, Lawrence B. Holzman, Ashish & Deepak Nihalani. (2012) Solution Structure Analysis of Cytoplasmic Domain of Podocyte Protein Neph1 Using Small/Wide Angle X-ray Scattering (SWAXS). Journal of Biological Chemistry 287:12, pages 9441-9453.
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Britta George, Rakesh Verma, Abdulsalam A. Soofi, Puneet Garg, Jidong Zhang, Tae-Ju Park, Laura Giardino, Larisa Ryzhova, Duncan B. Johnstone, Hetty Wong, Deepak Nihalani, David J. Salant, Steven K. Hanks, Tom Curran, Maria Pia Rastaldi & Lawrence B. Holzman. (2012) Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease. Journal of Clinical Investigation 122:2, pages 674-692.
Crossref
Aihua Zhang & Songming Huang. (2012) Progress in Pathogenesis of Proteinuria. International Journal of Nephrology 2012, pages 1-14.
Crossref
Madhusudan Venkatareddy, Leslie Cook, Kamal Abuarquob, Rakesh Verma & Puneet Garg. (2011) Nephrin Regulates Lamellipodia Formation by Assembling a Protein Complex That Includes Ship2, Filamin and Lamellipodin. PLoS ONE 6:12, pages e28710.
Crossref
Anna Greka & Peter Mundel. (2011) Balancing Calcium Signals through TRPC5 and TRPC6 in Podocytes. Journal of the American Society of Nephrology 22:11, pages 1969-1980.
Crossref
Sylvia Menzel & Marcus J. Moeller. (2011) Role of the podocyte in proteinuria. Pediatric Nephrology 26:10, pages 1775-1780.
Crossref
Maiaro Cabral Rosa Machado, Shirlei Octacilio-Silva, Mara Silvia A. Costa & Ricardo Guelerman P. Ramos. (2011) rst Transcriptional Activity Influences kirre mRNA Concentration in the Drosophila Pupal Retina during the Final Steps of Ommatidial Patterning. PLoS ONE 6:8, pages e22536.
Crossref
Puneet Garg & Ton Rabelink. (2011) Glomerular Proteinuria: A Complex Interplay Between Unique Players. Advances in Chronic Kidney Disease 18:4, pages 233-242.
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Rasheed Gbadegesin, Peter Lavin, John Foreman & Michelle Winn. (2011) Pathogenesis and therapy of focal segmental glomerulosclerosis: an update. Pediatric Nephrology 26:7, pages 1001-1015.
Crossref
Seisuke Hattori, Shoichiro Kanda & Yutaka Harita. (2011) Tyrosine Kinase Signaling in Kidney Glomerular Podocytes. Journal of Signal Transduction 2011, pages 1-10.
Crossref
Eija Heikkilä, Mervi Ristola, Marika Havana, Nina Jones, Harry Holthöfer & Sanna Lehtonen. (2011) Trans -interaction of nephrin and Neph1/Neph3 induces cell adhesion that associates with decreased tyrosine phosphorylation of nephrin . Biochemical Journal 435:3, pages 619-628.
Crossref
Ivo Quack, Magdalena Woznowski, Sebastian A. Potthoff, Romy Palmer, Eva Königshausen, Sema Sivritas, Mario Schiffer, Johannes Stegbauer, Oliver Vonend, Lars Christian Rump & Lorenz Sellin. (2011) PKCα Mediates β-Arrestin2-dependent Nephrin Endocytosis in Hyperglycemia. Journal of Biological Chemistry 286:15, pages 12959-12970.
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Kazuhiko Nishida, Kazuhide Nakayama, Saori Yoshimura & Fujio Murakami. (2011) Role of Neph2 in pontine nuclei formation in the developing hindbrain. Molecular and Cellular Neuroscience 46:3, pages 662-670.
Crossref
Xiaofeng Zhou & Jeffrey L. Platt. 2011. Cell Fusion in Health and Disease. Cell Fusion in Health and Disease 33 64 .
Jeffrey S. Simske & Jeff Hardin. 2011. Claudins. Claudins 147 169 .
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Crossref
Eduardo Machuca, Geneviève Benoit, Fabien Nevo, Marie-Josèphe Tête, Olivier Gribouval, Audrey Pawtowski, Per Brandström, Chantal Loirat, Patrick Niaudet, Marie-Claire Gubler & Corinne Antignac. (2010) Genotype–Phenotype Correlations in Non-Finnish Congenital Nephrotic Syndrome. Journal of the American Society of Nephrology 21:7, pages 1209-1217.
Crossref
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Crossref
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Crossref
Ying Zhang, Yutaka Yoshida, Masaaki Nameta, Bo Xu, Izumi Taguchi, Takako Ikeda, Hidehiko Fujinaka, Sameh Magdeldin Mohamed, Hiroyasu Tsukaguchi, Yutaka Harita, Eishin Yaoita & Tadashi Yamamoto. (2010) Glomerular proteins related to slit diaphragm and matrix adhesion in the foot processes are highly tyrosine phosphorylated in the normal rat kidney. Nephrology Dialysis Transplantation 25:6, pages 1785-1795.
Crossref
Jaakko Patrakka & Karl Tryggvason. (2010) Molecular make-up of the glomerular filtration barrier. Biochemical and Biophysical Research Communications 396:1, pages 164-169.
Crossref
Jianxin Zhu, Ortal Attias, Lamine Aoudjit, Ruihua Jiang, Hiroshi Kawachi & Tomoko Takano. (2010) p21-Activated kinases regulate actin remodeling in glomerular podocytes. American Journal of Physiology-Renal Physiology 298:4, pages F951-F961.
Crossref
Geneviève Benoit, Eduardo Machuca, Fabien Nevo, Olivier Gribouval, David Lepage & Corinne Antignac. (2009) Analysis of recessive CD2AP and ACTN4 mutations in steroid-resistant nephrotic syndrome. Pediatric Nephrology 25:3, pages 445-451.
Crossref
Alessia FornoniJongmin JeonJavier Varona SantosLorenzo CobianchiAlexandra JaureguiLuca InverardiSlavena A. MandicChristina BarkKevin JohnsonGeorge McNamaraAntonello PileggiR. Damaris MolanoJochen ReiserKarl TryggvasonDontscho KerjaschkiPer-Olof BerggrenPeter MundelCamillo Ricordi. (2010) Nephrin Is Expressed on the Surface of Insulin Vesicles and Facilitates Glucose-Stimulated Insulin Release. Diabetes 59:1, pages 190-199.
Crossref
Kazuhiko Nishida, Mikio Hoshino, Yoshiya Kawaguchi & Fujio Murakami. (2010) Ptf1a Directly Controls Expression of Immunoglobulin Superfamily Molecules Nephrin and Neph3 in the Developing Central Nervous System. Journal of Biological Chemistry 285:1, pages 373-380.
Crossref
Eun Young Kim, Yu-Hsin Chiu & Stuart E. Dryer. (2009) Neph1 regulates steady-state surface expression of Slo1 Ca 2+ -activated K + channels: different effects in embryonic neurons and podocytes . American Journal of Physiology-Cell Physiology 297:6, pages C1379-C1388.
Crossref
E. Machuca, G. Benoit & C. Antignac. (2009) Genetics of nephrotic syndrome: connecting molecular genetics to podocyte physiology. Human Molecular Genetics 18:R2, pages R185-R194.
Crossref
Martin Zenker, Eduardo Machuca & Corinne Antignac. (2009) Genetics of nephrotic syndrome: new insights into molecules acting at the glomerular filtration barrier. Journal of Molecular Medicine 87:9, pages 849-857.
Crossref
Stanley S. Stylli, Stacey T. T. I, Anne M. Verhagen, San San Xu, Ian Pass, Sara A. Courtneidge & Peter Lock. (2009) Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation. Journal of Cell Science 122:15, pages 2727-2740.
Crossref
Jaakko Patrakka & Karl Tryggvason. (2009) New insights into the role of podocytes in proteinuria. Nature Reviews Nephrology 5:8, pages 463-468.
Crossref
Shufei ZhuangHuanjie ShaoFengli GuoRhonda TrimbleElspeth PearceSusan M. Abmayr. (2009) Sns and Kirre, the Drosophila orthologs of Nephrin and Neph1,direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes . Development 136:14, pages 2335-2344.
Crossref
Claudio R. Simon, Livia M.R. Moda, Shirlei Octacilio-Silva, Lucas Anhezini, Luciana C.H. Machado-Gitai & Ricardo Guelerman P. Ramos. (2009) Precise temporal regulation of roughest is required for correct salivary gland autophagic cell death in Drosophila . genesis 47:7, pages 492-504.
Crossref
Peter W Mathieson. (2009) Update on the podocyte. Current Opinion in Nephrology and Hypertension 18:3, pages 206-211.
Crossref
Yutaka Harita, Hidetake Kurihara, Hidetaka Kosako, Tohru Tezuka, Takashi Sekine, Takashi Igarashi, Ikuroh Ohsawa, Shigeo Ohta & Seisuke Hattori. (2009) Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-γ1. Journal of Biological Chemistry 284:13, pages 8951-8962.
Crossref
S.F. Heeringa & F. Hildebrandt. (2009) Monogene Ursachen des nephrotischen SyndromsMonogenetic causes of nephrotic syndrome. Monatsschrift Kinderheilkunde 157:3, pages 218-225.
Crossref
Sheng Xiao, Jun Wang, Jianwei Jiang, Xiaoding Cao, Gencheng Wu & Hui Zhao. (2009) Characterization of Fyn signaling on the age-dependent immuno-modulation on traumatic rats. Brain Research 1255, pages 162-169.
Crossref
Ernie L. Esquivel & Corinne Antignac. 2009. Genetic Diseases of the Kidney. Genetic Diseases of the Kidney 97 111 .
Mark C. Wagner, George Rhodes, Exing Wang, Vikas Pruthi, Ehtesham Arif, Moin A. Saleem, Sarah E. Wean, Puneet Garg, Rakesh Verma, Lawrence B. Holzman, Vince Gattone, Bruce A. Molitoris & Deepak Nihalani. (2008) Ischemic Injury to Kidney Induces Glomerular Podocyte Effacement and Dissociation of Slit Diaphragm Proteins Neph1 and ZO-1. Journal of Biological Chemistry 283:51, pages 35579-35589.
Crossref
Hongyu Zhang, Jharna Saha, Jaeman Byun, MaryLee Schin, Matthew Lorenz, Robert T. Kennedy, Matthias Kretzler, Eva L. Feldman, Subramaniam Pennathur & Frank C. BrosiusIIIIII. (2008) Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy. American Journal of Physiology-Renal Physiology 295:4, pages F1071-F1081.
Crossref
Eun Young Kim, Kyoung-Jae Choi & Stuart E. Dryer. (2008) Nephrin binds to the COOH terminus of a large-conductance Ca 2+ -activated K + channel isoform and regulates its expression on the cell surface . American Journal of Physiology-Renal Physiology 295:1, pages F235-F246.
Crossref
Peter J Lavin, Rasheed Gbadegesin, Tirupapuliyur V Damodaran & Michelle P Winn. (2008) Therapeutic targets in focal and segmental glomerulosclerosis. Current Opinion in Nephrology and Hypertension 17:4, pages 386-392.
Crossref
Yutaka Harita, Hidetake Kurihara, Hidetaka Kosako, Tohru Tezuka, Takashi Sekine, Takashi Igarashi & Seisuke Hattori. (2008) Neph1, a Component of the Kidney Slit Diaphragm, Is Tyrosine-phosphorylated by the Src Family Tyrosine Kinase and Modulates Intracellular Signaling by Binding to Grb2. Journal of Biological Chemistry 283:14, pages 9177-9186.
Crossref
S. Lehtonen. (2008) Connecting the interpodocyte slit diaphragm and actin dynamics: Emerging role for the nephrin signaling complex. Kidney International 73:8, pages 903-905.
Crossref
Martin R Pollak. (2008) Focal segmental glomerulosclerosis: recent advances. Current Opinion in Nephrology & Hypertension 17:2, pages 138-142.
Crossref
Margaret Cobb Neville, Patricia G. Webb, Heidi K. Baumgartner & Benjamin G. Bitler. (2022) Claudin-4 Localization in Epithelial Ovarian Cancer. SSRN Electronic Journal.
Crossref

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