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Article

DYRK1A and Glycogen Synthase Kinase 3β, a Dual-Kinase Mechanism Directing Proteasomal Degradation of CRY2 for Circadian Timekeeping

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Pages 1757-1768 | Received 07 Aug 2009, Accepted 18 Jan 2010, Published online: 20 Mar 2023

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Priya Crosby & Carrie L. Partch. (2020) New insights into non-transcriptional regulation of mammalian core clock proteins. Journal of Cell Science 133:18.
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Tomasz Jaworski. (2020) Control of neuronal excitability by GSK-3beta: Epilepsy and beyond. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1867:9, pages 118745.
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Simon Miller & Tsuyoshi Hirota. (2020) Pharmacological Interventions to Circadian Clocks and Their Molecular Bases. Journal of Molecular Biology 432:12, pages 3498-3514.
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Helen C. Causton. (2018) Metabolic rhythms: A framework for coordinating cellular function. European Journal of Neuroscience 51:1, pages 1-12.
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Yool Lee, Yang Shen, Lauren J. Francey, Chidambaram Ramanathan, Amita Sehgal, Andrew C. Liu & John B. Hogenesch. (2019) The NRON complex controls circadian clock function through regulated PER and CRY nuclear translocation. Scientific Reports 9:1.
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Simone Granno, Jonathon Nixon-Abell, Daniel C. Berwick, Justin Tosh, George Heaton, Sultan Almudimeegh, Zenisha Nagda, Jean-Christophe Rain, Manuela Zanda, Vincent Plagnol, Victor L. J. Tybulewicz, Karen Cleverley, Frances K. Wiseman, Elizabeth M. C. Fisher & Kirsten Harvey. (2019) Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus. Scientific Reports 9:1.
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Hyo Kyeong Cha, Sooyoung Chung, Hye Young Lim, Jong-Wha Jung & Gi Hoon Son. (2019) Small Molecule Modulators of the Circadian Molecular Clock With Implications for Neuropsychiatric Diseases. Frontiers in Molecular Neuroscience 11.
Crossref
Krisztina Ella, Attila Mócsai & Krisztina Káldi. (2018) Circadian regulation of neutrophils: Control by a cell-autonomous clock or systemic factors?. European Journal of Clinical Investigation 48, pages e12965.
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Jean-François Costemale-Lacoste, Romain Colle, Séverine Martin, Khalil El Asmar, Emanuel Loeb, Bruno Feve, Céline Verstuyft, Séverine Trabado, Florian Ferreri, Emmanuel Haffen, Mircea Polosan, Laurent Becquemont & Emmanuelle Corruble. (2018) Glycogen synthase kinase-3β genetic polymorphisms and insomnia in depressed patients: A prospective study. Journal of Affective Disorders 240, pages 230-236.
Crossref
David CS Wong & John S O’Neill. (2018) Non-transcriptional processes in circadian rhythm generation. Current Opinion in Physiology 5, pages 117-132.
Crossref
Koji L. Ode & Hiroki R. Ueda. (2018) Design Principles of Phosphorylation-Dependent Timekeeping in Eukaryotic Circadian Clocks. Cold Spring Harbor Perspectives in Biology 10:8, pages a028357.
Crossref
Se Hyun Kim, Hong Geun Park, Seong Hoon Jeong, Ung Gu Kang, Yong Min Ahn & Yong Sik Kim. (2018) Electroconvulsive Seizure Alters the Expression and Daily Oscillation of Circadian Genes in the Rat Frontal Cortex. Psychiatry Investigation 15:7, pages 717-726.
Crossref
Naoto Hayasaka, Arisa Hirano, Yuka Miyoshi, Isao T Tokuda, Hikari Yoshitane, Junichiro Matsuda & Yoshitaka Fukada. (2017) Salt-inducible kinase 3 regulates the mammalian circadian clock by destabilizing PER2 protein. eLife 6.
Crossref
Maria Nathália Moraes, Leonardo Vinicius Monteiro de Assis, Felipe dos Santos Henriques, Miguel Luiz Batista Jr, Ali D. Güler & Ana Maria de Lauro Castrucci. (2017) Cold-sensing TRPM8 channel participates in circadian control of the brown adipose tissue. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1864:12, pages 2415-2427.
Crossref
Rajeev Singh & Matthias Lauth. (2017) Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control. Journal of Developmental Biology 5:4, pages 13.
Crossref
Minnie FuXiaoyong Yang. (2017) The sweet tooth of the circadian clock. Biochemical Society Transactions 45:4, pages 871-884.
Crossref
Qing Liu, Qin Wang, Weixian Deng, Xu Wang, Mingxin Piao, Dawei Cai, Yaxing Li, William D. Barshop, Xiaolan Yu, Tingting Zhou, Bin Liu, Yoshito Oka, James Wohlschlegel, Zecheng Zuo & Chentao Lin. (2017) Molecular basis for blue light-dependent phosphorylation of Arabidopsis cryptochrome 2. Nature Communications 8:1.
Crossref
Jodi R. Paul, Alex S. McKeown, Jennifer A. Davis, Stacie K. Totsch, Eric M. Mintz, Timothy W. Kraft, Rita M. Cowell & Karen L. Gamble. (2017) Glycogen synthase kinase 3 regulates photic signaling in the suprachiasmatic nucleus. European Journal of Neuroscience 45:8, pages 1102-1110.
Crossref
Lucia Mendoza-Viveros, Pascale Bouchard-Cannon, Sara Hegazi, Arthur H. Cheng, Stephen Pastore & Hai-Ying Mary Cheng. (2016) Molecular modulators of the circadian clock: lessons from flies and mice. Cellular and Molecular Life Sciences 74:6, pages 1035-1059.
Crossref
Ekaterina Sigitova, Zdeněk Fišar, Jana Hroudová, Tereza Cikánková & Jiří Raboch. (2017) Biological hypotheses and biomarkers of bipolar disorder. Psychiatry and Clinical Neurosciences 71:2, pages 77-103.
Crossref
Maria Nathalia Moraes, Nathana Mezzalira, Leonardo Vinicius Monteiro de Assis, Michael Menaker, Ali Guler & Ana Maria L. Castrucci. (2017) TRPV1 participates in the activation of clock molecular machinery in the brown adipose tissue in response to light-dark cycle. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1864:2, pages 324-335.
Crossref
Arisa Hirano, Ying-Hui Fu & Louis J Ptáček. (2016) The intricate dance of post-translational modifications in the rhythm of life. Nature Structural & Molecular Biology 23:12, pages 1053-1060.
Crossref
Na Liu & Eric Erquan Zhang. (2016) Phosphorylation Regulating the Ratio of Intracellular CRY1 Protein Determines the Circadian Period. Frontiers in Neurology 7.
Crossref
Arnaud Duchon & Yann Herault. (2016) DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome. Frontiers in Behavioral Neuroscience 10.
Crossref
Arisa Hirano, Tomoki Nakagawa, Hikari Yoshitane, Masaaki Oyama, Hiroko Kozuka-Hata, Darin Lanjakornsiripan & Yoshitaka Fukada. (2016) USP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein Stability Paces the Oscillation of the Mammalian Circadian Clock. PLOS ONE 11:4, pages e0154263.
Crossref
Takako Noguchi, Kevin Lo, Tanja Diemer & David K. Welsh. (2016) Lithium effects on circadian rhythms in fibroblasts and suprachiasmatic nucleus slices from Cry knockout mice. Neuroscience Letters 619, pages 49-53.
Crossref
Aleix Ribas-Latre & Kristin Eckel-Mahan. (2016) Interdependence of nutrient metabolism and the circadian clock system: Importance for metabolic health. Molecular Metabolism 5:3, pages 133-152.
Crossref
Soujanya D. Yelamanchi, Manish Kumar, Anil K. Madugundu, Lathika Gopalakrishnan, Gourav Dey, Sandip Chavan, Gajanan Sathe, Premendu P. Mathur, Harsha Gowda, Anita Mahadevan, Susarla K. Shankar & T. S. Keshava Prasad. (2016) Characterization of human pineal gland proteome. Molecular BioSystems 12:12, pages 3622-3632.
Crossref
B W M van Bon, B P Coe, R Bernier, C Green, J Gerdts, K Witherspoon, T Kleefstra, M H Willemsen, R Kumar, P Bosco, M Fichera, D Li, D Amaral, F Cristofoli, H Peeters, E Haan, C Romano, H C Mefford, I Scheffer, J Gecz, B B A de Vries & E E Eichler. (2015) Disruptive de novo mutations of DYRK1A lead to a syndromic form of autism and ID. Molecular Psychiatry 21:1, pages 126-132.
Crossref
Ramzi Abbassi, Terrance G. Johns, Michael Kassiou & Lenka Munoz. (2015) DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications. Pharmacology & Therapeutics 151, pages 87-98.
Crossref
Torsten Merbitz-Zahradnik & Eva Wolf. (2015) How is the inner circadian clock controlled by interactive clock proteins?. FEBS Letters 589:14, pages 1516-1529.
Crossref
Rachel C. Besing, Jodi R. Paul, Lauren M. Hablitz, Courtney O. Rogers, Russell L. Johnson, Martin E. Young & Karen L. Gamble. (2015) Circadian Rhythmicity of Active GSK3 Isoforms Modulates Molecular Clock Gene Rhythms in the Suprachiasmatic Nucleus. Journal of Biological Rhythms 30:2, pages 155-160.
Crossref
Chelsea L. Gustafson & Carrie L. Partch. (2014) Emerging Models for the Molecular Basis of Mammalian Circadian Timing. Biochemistry 54:2, pages 134-149.
Crossref
Woo-Joo Song, Eun-Ah Christine Song, Min-Su Jung, Sun-Hee Choi, Hyung-Hwan Baik, Byung Kwan Jin, Jeong Hee Kim & Sul-Hee Chung. (2015) Phosphorylation and Inactivation of Glycogen Synthase Kinase 3β (GSK3β) by Dual-specificity Tyrosine Phosphorylation-regulated Kinase 1A (Dyrk1A). Journal of Biological Chemistry 290:4, pages 2321-2333.
Crossref
Hikari Yoshitane & Yoshitaka Fukada. 2015. Protein Modifications in Pathogenic Dysregulation of Signaling. Protein Modifications in Pathogenic Dysregulation of Signaling 251 268 .
Yoshihiko Miyata. 2015. Protein Kinase CK2 Cellular Function in Normal and Disease States. Protein Kinase CK2 Cellular Function in Normal and Disease States 341 359 .
Katarina Stojkovic, Simon S. Wing & Nicolas Cermakian. (2014) A central role for ubiquitination within a circadian clock protein modification code. Frontiers in Molecular Neuroscience 7.
Crossref
Yaoming Yang, David Duguay, Jan Fahrenkrug, Nicolas Cermakian & Simon S. Wing. (2014) USP2 Regulates the Intracellular Localization of PER1 and Circadian Gene Expression. Journal of Biological Rhythms 29:4, pages 243-256.
Crossref
Qiang Liu, Na Liu, Shaolei Zang, Heng Liu, Pin Wang, Chunyan Ji & Xiulian Sun. (2014) Tumor Suppressor DYRK1A Effects on Proliferation and Chemoresistance of AML Cells by Downregulating c-Myc. PLoS ONE 9:6, pages e98853.
Crossref
Christian Schmitt, Dagmar Kail, Marica Mariano, Martin Empting, Nadja Weber, Tamara Paul, Rolf W. Hartmann & Matthias Engel. (2014) Design and Synthesis of a Library of Lead-Like 2,4-Bisheterocyclic Substituted Thiophenes as Selective Dyrk/Clk Inhibitors. PLoS ONE 9:3, pages e87851.
Crossref
Peter C. St. JohnTsuyoshi Hirota, Steve A. Kay & Francis J. DoyleIIIIII. (2014) Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock. Proceedings of the National Academy of Sciences 111:5, pages 2040-2045.
Crossref
Ruoting Yang, Maria Rodriguez-Fernandez, Peter C. St. John & Francis J DoyleIIIIII. 2014. Modelling Methodology for Physiology and Medicine. Modelling Methodology for Physiology and Medicine 159 187 .
Peng Gao, Seung-Hee Yoo, Kyung-Jong Lee, Clark Rosensweig, Joseph S. Takahashi, Benjamin P. Chen & Carla B. Green. (2013) Phosphorylation of the Cryptochrome 1 C-terminal Tail Regulates Circadian Period Length. Journal of Biological Chemistry 288:49, pages 35277-35286.
Crossref
Kanae Yumimoto, Tetsuya Muneoka, Tomohiro Tsuboi & Keiichi I. Nakayama. (2013) Substrate Binding Promotes Formation of the Skp1-Cul1-Fbxl3 (SCFFbxl3) Protein Complex. Journal of Biological Chemistry 288:45, pages 32766-32776.
Crossref
Ethan Buhr & Joseph S. Takahashi. 2013. The Genetic Basis of Sleep and Sleep Disorders. The Genetic Basis of Sleep and Sleep Disorders 119 126 .
. 2013. The Genetic Basis of Sleep and Sleep Disorders. The Genetic Basis of Sleep and Sleep Disorders 33 138 .
Xin Tong & Lei Yin. 2011. Comprehensive Physiology. Comprehensive Physiology 917 940 .
Arisa Hirano, Kanae Yumimoto, Ryosuke Tsunematsu, Masaki Matsumoto, Masaaki Oyama, Hiroko Kozuka-Hata, Tomoki Nakagawa, Darin Lanjakornsiripan, Keiichi I. Nakayama & Yoshitaka Fukada. (2013) FBXL21 Regulates Oscillation of the Circadian Clock through Ubiquitination and Stabilization of Cryptochromes. Cell 152:5, pages 1106-1118.
Crossref
John S. O’Neill, Elizabeth S. Maywood & Michael H. Hastings. 2013. Circadian Clocks. Circadian Clocks 67 103 .
Ethan D. Buhr & Joseph S. Takahashi. 2013. Circadian Clocks. Circadian Clocks 3 27 .
J.R. Paul, R.L. Johnson, R.S. Jope & K.L. Gamble. (2012) Disruption of circadian rhythmicity and suprachiasmatic action potential frequency in a mouse model with constitutive activation of glycogen synthase kinase 3. Neuroscience 226, pages 1-9.
Crossref
Gerben van Ooijen & Andrew J. Millar. (2012) Non-transcriptional oscillators in circadian timekeeping. Trends in Biochemical Sciences 37:11, pages 484-492.
Crossref
Özgür Tataroğlu, Linda Lauinger, Gencer Sancar, Katharina Jakob, Michael Brunner & Axel C.R. Diernfellner. (2012) Glycogen Synthase Kinase Is a Regulator of the Circadian Clock of Neurospora crassa. Journal of Biological Chemistry 287:44, pages 36936-36943.
Crossref
Xiumei Guo, Mehmet Kesimer, Gökhan Tolun, Xunhai Zheng, Qing Xu, Jing Lu, John K. Sheehan, Jack D. Griffith & Xiaoling Li. (2012) The NAD+-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status. Scientific Reports 2:1.
Crossref
Tsuyoshi HirotaJae Wook LeePeter C. St. JohnMariko SawaKeiko IwaisakoTakako NoguchiPagkapol Y. PongsawakulTim SonntagDavid K. WelshDavid A. BrennerFrancis J. DoyleIIIIIIPeter G. SchultzSteve A. Kay. (2012) Identification of Small Molecule Activators of Cryptochrome. Science 337:6098, pages 1094-1097.
Crossref
Yaoming Yang, David Duguay, Nathalie Bédard, Adeline Rachalski, Gerardo Baquiran, Chan Hyun Na, Jan Fahrenkrug, Kai-Florian Storch, Junmin Peng, Simon S. Wing & Nicolas Cermakian. (2012) Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2. Biology Open 1:8, pages 789-801.
Crossref
Xin Tong, Katie Buelow, Anirvan Guha, Rebecca Rausch & Lei Yin. (2012) USP2a Protein Deubiquitinates and Stabilizes the Circadian Protein CRY1 in Response to Inflammatory Signals. Journal of Biological Chemistry 287:30, pages 25280-25291.
Crossref
Olivia Sheppard, Florian Plattner, Anna Rubin, Amy Slender, Jacqueline M. Linehan, Sebastian Brandner, Victor L.J. Tybulewicz, Elizabeth M.C. Fisher & Frances K. Wiseman. (2012) Altered regulation of tau phosphorylation in a mouse model of down syndrome aging. Neurobiology of Aging 33:4, pages 828.e31-828.e44.
Crossref
M. J. McCarthy, C. M. Nievergelt, T. Shekhtman, D. F. Kripke, D. K. Welsh & J. R. Kelsoe. (2011) Functional genetic variation in the Rev-Erb α pathway and lithium response in the treatment of bipolar disorder . Genes, Brain and Behavior 10:8, pages 852-861.
Crossref
Yoshihiko Miyata & Eisuke Nishida. (2011) DYRK1A binds to an evolutionarily conserved WD40-repeat protein WDR68 and induces its nuclear translocation. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1813:10, pages 1728-1739.
Crossref
Colleen A. McClung. (2011) Circadian rhythms and mood regulation: Insights from pre-clinical models. European Neuropsychopharmacology 21, pages S683-S693.
Crossref
Anna Czarna, Helena Breitkreuz, Carsten C. Mahrenholz, Julia Arens, Holger M. Strauss & Eva Wolf. (2011) Quantitative Analyses of Cryptochrome-mBMAL1 Interactions. Journal of Biological Chemistry 286:25, pages 22414-22425.
Crossref
Silke Reischl & Achim Kramer. (2011) Kinases and phosphatases in the mammalian circadian clock. FEBS Letters 585:10, pages 1393-1399.
Crossref
Walter Becker & Wolfgang Sippl. (2011) Activation, regulation, and inhibition of DYRK1A. FEBS Journal 278:2, pages 246-256.
Crossref
Francisco J. Tejedor & Barbara Hämmerle. (2011) MNB/DYRK1A as a multiple regulator of neuronal development. FEBS Journal 278:2, pages 223-235.
Crossref
Phillip L. Lowrey & Joseph S. Takahashi. 2011. The Genetics of Circadian Rhythms. The Genetics of Circadian Rhythms 175 230 .

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