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Molecular and Cellular Biology Volume 26, 2006 - Issue 21
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Article

Human Immunodeficiency Virus Type 1 Vpr Induces G2 Checkpoint Activation by Interacting with the Splicing Factor SAP145

Yasuhiko Terada1 Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota55455;2 Louis Pasteur Center for Medical Research, Cell Biology Section, Division of Basic Research, 103-5, Tanaka Monzen-cho, Sakyo-ku, Kyoto606-8225, JapanCorrespondence[email protected]
&
Yuko Yasuda2 Louis Pasteur Center for Medical Research, Cell Biology Section, Division of Basic Research, 103-5, Tanaka Monzen-cho, Sakyo-ku, Kyoto606-8225, Japan
Pages 8149-8158 | Received 28 Jun 2006, Accepted 08 Aug 2006, Published online: 27 Mar 2023

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Zodwa Dlamini & Rodney Hull. (2017) Can the HIV-1 splicing machinery be targeted for drug discovery?. HIV/AIDS - Research and Palliative Care 9, pages 63-75.
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A. Chowdhury, G. Liu, M. Kemp, X. Chen, N. Katrangi, S. Myers, M. Ghosh, J. Yao, Y. Gao, P. Bubulya & M. Leffak. (2010) The DNA Unwinding Element Binding Protein DUE-B Interacts with Cdc45 in Preinitiation Complex Formation. Molecular and Cellular Biology 30:6, pages 1495-1507.
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Articles from other publishers (24)

Sara Cristinelli, Paolo Angelino, Andrew Janowczyk, Mauro Delorenzi & Angela Ciuffi. (2021) HIV Modifies the m6A and m5C Epitranscriptomic Landscape of the Host Cell. Frontiers in Virology 1.
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Joseph Dopie, Michael J. Sweredoski, Annie Moradian & Andrew S. Belmont. (2020) Tyramide signal amplification mass spectrometry (TSA-MS) ratio identifies nuclear speckle proteins. Journal of Cell Biology 219:9.
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Chengfu Sun. (2020) The SF3b complex: splicing and beyond. Cellular and Molecular Life Sciences 77:18, pages 3583-3595.
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Sihua Liu, Hongyun Liu, Jun Kang, Leling Xu, Keke Zhang, Xueping Li, Wen Hou, Zhiyun Wang & Tao Wang. (2020) The Severe Fever with Thrombocytopenia Syndrome Virus NSs Protein Interacts with CDK1 To Induce G 2 Cell Cycle Arrest and Positively Regulate Viral Replication . Journal of Virology 94:6.
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Helena Fabryova & Klaus Strebel. (2019) Vpr and Its Cellular Interaction Partners: R We There Yet?. Cells 8:11, pages 1310.
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Edward J.D. Greenwood, James C. Williamson, Agata Sienkiewicz, Adi Naamati, Nicholas J. Matheson & Paul J. Lehner. (2019) Promiscuous Targeting of Cellular Proteins by Vpr Drives Systems-Level Proteomic Remodeling in HIV-1 Infection. Cell Reports 27:5, pages 1579-1596.e7.
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Daniel Sauter & Frank Kirchhoff. (2018) Multilayered and versatile inhibition of cellular antiviral factors by HIV and SIV accessory proteins. Cytokine & Growth Factor Reviews 40, pages 3-12.
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Edwin H. Yau, Indrasena Reddy Kummetha, Gianluigi Lichinchi, Rachel Tang, Yunlin Zhang & Tariq M. Rana. (2017) Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers. Cancer Research 77:22, pages 6330-6339.
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Kanako Kuwasako, Nobukazu Nameki, Kengo Tsuda, Mari Takahashi, Atsuko Sato, Naoya Tochio, Makoto Inoue, Takaho Terada, Takanori Kigawa, Naohiro Kobayashi, Mikako Shirouzu, Takuhiro Ito, Taiichi Sakamoto, Kaori Wakamatsu, Peter Güntert, Seizo Takahashi, Shigeyuki Yokoyama & Yutaka Muto. (2017) Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment. Protein Science 26:2, pages 280-291.
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Andrea Hadjikyriacou, Yanzhong Yang, Alexsandra Espejo, Mark T. Bedford & Steven G. Clarke. (2015) Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2. Journal of Biological Chemistry 290:27, pages 16723-16743.
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Yanzhong Yang, Andrea Hadjikyriacou, Zheng Xia, Sitaram Gayatri, Daehoon Kim, Cecilia Zurita-Lopez, Ryan Kelly, Ailan Guo, Wei Li, Steven G. Clarke & Mark T. Bedford. (2015) PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145. Nature Communications 6:1.
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Adam Burgener, Annelie Tjernlund, Tove Kaldensjo, Max Abou, Stuart McCorrister, Garrett R. Westmacott, Kenzie Mogk, Emma Ambrose, Kristina Broliden & Blake Ball. (2013) A Systems Biology Examination of the Human Female Genital Tract Shows Compartmentalization of Immune Factor Expression. Journal of Virology 87:9, pages 5141-5150.
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Winnie H Sim, Josef Wagner, Donald J Cameron, Anthony G Catto-Smith, Ruth F Bishop & Carl D Kirkwood. (2012) Expression profile of genes involved in pathogenesis of pediatric Crohn's disease. Journal of Gastroenterology and Hepatology 27:6, pages 1083-1093.
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Nidhanapati K Raghavendra, Nikolozi Shkriabai, Robert LJ Graham, Sonja Hess, Mamuka Kvaratskhelia & Li Wu. (2010) Identification of host proteins associated with HIV-1 preintegration complexes isolated from infected CD4+ cells. Retrovirology 7:1.
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Jinwoo Ahn, Thomas Vu, Zach Novince, Jennifer Guerrero-Santoro, Vesna Rapic-Otrin & Angela M. Gronenborn. (2010) HIV-1 Vpr Loads Uracil DNA Glycosylase-2 onto DCAF1, a Substrate Recognition Subunit of a Cullin 4A-RING E3 Ubiquitin Ligase for Proteasome-dependent Degradation. Journal of Biological Chemistry 285:48, pages 37333-37341.
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Joëlle V Fritz, Laurence Briant, Yves Mély, Serge Bouaziz & Hugues de Rocquigny. (2010) HIV-1 viral protein r: from structure to function. Future Virology 5:5, pages 607-625.
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C. Martin Stoltzfus. 2009. 1 40 .
Vicente Planelles & Serge Benichou. 2009. HIV Interactions with Host Cell Proteins. HIV Interactions with Host Cell Proteins 177 200 .
Joshua L. Andersen, Erwann Le Rouzic & Vicente Planelles. (2008) HIV-1 Vpr: Mechanisms of G2 arrest and apoptosis. Experimental and Molecular Pathology 85:1, pages 2-10.
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Magnus Sundstrom, Udayan Chatterji, Lana Schaffer, Sohela de Rozières & John H. Elder. (2008) Feline immunodeficiency virus OrfA alters gene expression of splicing factors and proteasome-ubiquitination proteins. Virology 371:2, pages 394-404.
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Clare Davy & John Doorbar. (2007) G2/M cell cycle arrest in the life cycle of viruses. Virology 368:2, pages 219-226.
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Betty Poon, Michael A. Chang & Irvin S. Y. Chen. (2007) Vpr Is Required for Efficient Nef Expression from Unintegrated Human Immunodeficiency Virus Type 1 DNA. Journal of Virology 81:19, pages 10515-10523.
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Chieko Hashizume, Madoka Kuramitsu, Xianfeng Zhang, Terue Kurosawa, Masakazu Kamata & Yoko Aida. (2007) Human immunodeficiency virus type 1 Vpr interacts with spliceosomal protein SAP145 to mediate cellular pre-mRNA splicing inhibition. Microbes and Infection 9:4, pages 490-497.
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Richard Y. Zhao, Robert T. Elder & Michael Bukrinsky. 2007. HIV‐1: Molecular Biology and Pathogenesis Viral Mechanisms, Second Edition. HIV‐1: Molecular Biology and Pathogenesis Viral Mechanisms, Second Edition 233 260 .

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