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Molecular and Cellular Biology Volume 33, 2013 - Issue 11
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Article

Fanconi Anemia Group J Helicase and MRE11 Nuclease Interact To Facilitate the DNA Damage Response

Avvaru N. Suhasinia Laboratory of Molecular Gerontology, National Institute on Aging, NIH, NIH Biomedical Research Center, Baltimore, Maryland, USA
,
Joshua A. Sommersa Laboratory of Molecular Gerontology, National Institute on Aging, NIH, NIH Biomedical Research Center, Baltimore, Maryland, USA
,
Parameswary A. Muniandya Laboratory of Molecular Gerontology, National Institute on Aging, NIH, NIH Biomedical Research Center, Baltimore, Maryland, USA
,
Yan Coulombeb Genome Stability Laboratory, Laval University Cancer Research Center, Quebec, Canada
,
Sharon B. Cantorc Department of Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
,
Jean-Yves Massonb Genome Stability Laboratory, Laval University Cancer Research Center, Quebec, Canada
,
Michael M. Seidmana Laboratory of Molecular Gerontology, National Institute on Aging, NIH, NIH Biomedical Research Center, Baltimore, Maryland, USA
&
Robert M. Brosh Jr.a Laboratory of Molecular Gerontology, National Institute on Aging, NIH, NIH Biomedical Research Center, Baltimore, Maryland, USACorrespondence[email protected]
 show all
Pages 2212-2227 | Received 12 Sep 2012, Accepted 14 Mar 2013, Published online: 20 Mar 2023

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Srijita Dhar & Robert M. Brosh. (2018) BLM’s balancing act and the involvement of FANCJ in DNA repair. Cell Cycle 17:18, pages 2207-2220.
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Sharon B Cantor & Robert M Brosh$suffix/text()$suffix/text(). (2014) What is wrong with Fanconi anemia cells?. Cell Cycle 13:24, pages 3823-3827.
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Articles from other publishers (39)

Kai Jiang, Yuanyuan Ding, Changjiang Dong, Feifei Shan, Kun Guo, Jiwang Zhang & Feng Zhang. (2022) BCLAF1, a functional partner of BACH1, participates in DNA damage response. DNA Repair 118, pages 103371.
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Katheeja Muhseena N, Sooraj Mathukkada, Shankar Prasad Das & Suparna Laha. (2021) The repair gene <em>BACH1</em> - a potential oncogene. Oncology Reviews 15:1.
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Robert M BroshJrJr & Yuliang Wu. (2021) An emerging picture of FANCJ’s role in G4 resolution to facilitate DNA replication. NAR Cancer 3:3.
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Jennifer A. Calvo, Briana Fritchman, Desiree Hernandez, Nicole S. Persky, Cory M. Johannessen, Federica Piccioni, Brian A. Kelch & Sharon B. Cantor. (2021) Comprehensive Mutational Analysis of the BRCA1-Associated DNA Helicase and Tumor-Suppressor FANCJ/BACH1/BRIP1. Molecular Cancer Research 19:6, pages 1015-1025.
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Pauline Lejault, Jérémie Mitteaux, Francesco Rota Sperti & David Monchaud. (2021) How to untie G-quadruplex knots and why?. Cell Chemical Biology 28:4, pages 436-455.
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Kailey Harrell, Madison Day & Sarit Smolikove. (2021) Recruitment of MRE-11 to complex DNA damage is modulated by meiosis-specific chromosome organization. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 822, pages 111743.
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Srijita Dhar, Arindam Datta & Robert M. BroshJr.Jr.. (2020) DNA helicases and their roles in cancer. DNA Repair 96, pages 102994.
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Sarmi Nath & Ganesh Nagaraju. (2020) FANCJ helicase promotes DNA end resection by facilitating CtIP recruitment to DNA double-strand breaks. PLOS Genetics 16:4, pages e1008701.
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Nicholas J. H. Warren & Alan Eastman. (2019) Comparison of the different mechanisms of cytotoxicity induced by checkpoint kinase I inhibitors when used as single agents or in combination with DNA damage. Oncogene 39:7, pages 1389-1401.
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Sanket Awate, Srijita Dhar, Joshua A. Sommers & Robert M. BroshJr.Jr.. 2019. DNA Repair. DNA Repair 185 207 .
Min Peng, Ke Cong, Nicholas J. Panzarino, Sumeet Nayak, Jennifer Calvo, Bin Deng, Lihua Julie Zhu, Monika Morocz, Lili Hegedus, Lajos Haracska & Sharon B. Cantor. (2018) Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress. Cell Reports 24:12, pages 3251-3261.
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Sanjay Kumar Bharti, Joshua A Sommers, Sanket Awate, Marina A Bellani, Irfan Khan, Lynda Bradley, Graeme A King, Yeonee Seol, Venkatasubramanian Vidhyasagar, Yuliang Wu, Takuye Abe, Koji Kobayashi, Kazuo Shin-ya, Hiroyuki Kitao, Marc S Wold, Dana Branzei, Keir C Neuman & Robert M BroshJrJr. (2018) A minimal threshold of FANCJ helicase activity is required for its response to replication stress or double-strand break repair. Nucleic Acids Research 46:12, pages 6238-6256.
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Sarmi Nath, Kumar Somyajit, Anup Mishra, Ralph Scully & Ganesh Nagaraju. (2017) FANCJ helicase controls the balance between short- and long-tract gene conversions between sister chromatids. Nucleic Acids Research 45:15, pages 8886-8900.
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R. Gadgil, J. Barthelemy, T. Lewis & M. Leffak. (2017) Replication stalling and DNA microsatellite instability. Biophysical Chemistry 225, pages 38-48.
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Wenwen Wu, Yukiko Togashi, Yoshikazu Johmura, Yasuo Miyoshi, Sachihiko Nobuoka, Makoto Nakanishi & Tomohiko Ohta. (2016) HP1 regulates the localization of FANCJ at sites of DNA double‐strand breaks . Cancer Science 107:10, pages 1406-1415.
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Manhong Guo, Venkatasubramanian Vidhyasagar, Tanu Talwar, Ahmad Kariem & Yuliang Wu. (2016) Mutational analysis of FANCJ helicase. Methods 108, pages 118-129.
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Joanna Barthelemy, Helmut Hanenberg & Michael Leffak. (2016) FANCJ is essential to maintain microsatellite structure genome-wide during replication stress. Nucleic Acids Research 44:14, pages 6803-6816.
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David Lopez-Martinez, Chih-Chao Liang & Martin A. Cohn. (2016) Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway. Cellular and Molecular Life Sciences 73:16, pages 3097-3114.
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Sharon B. Cantor & Sumeet Nayak. (2016) FANCJ at the FORK. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 788, pages 7-11.
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Teruaki Iyama & David M. WilsonIIIIII. (2016) Elements That Regulate the DNA Damage Response of Proteins Defective in Cockayne Syndrome. Journal of Molecular Biology 428:1, pages 62-78.
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David W. Clark, Kaushlendra Tripathi, Josephine C. Dorsman & Komaraiah Palle. (2015) FANCJ protein is important for the stability of FANCD2/FANCI proteins and protects them from proteasome and caspase-3 dependent degradation. Oncotarget 6:30, pages 28816-28832.
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Yang Xu, Xiling Wu & Chengtao Her. (2015) hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ. Journal of Biological Chemistry 290:30, pages 18545-18558.
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Marieke Aarts, Ilirjana Bajrami, Maria T. Herrera-Abreu, Richard Elliott, Rachel Brough, Alan Ashworth, Christopher J. Lord & Nicholas C. Turner. (2015) Functional Genetic Screen Identifies Increased Sensitivity to WEE1 Inhibition in Cells with Defects in Fanconi Anemia and HR Pathways. Molecular Cancer Therapeutics 14:4, pages 865-876.
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Andrea BjörkmanPer QvistLikun DuMargarita BartishApostolos ZaravinosKonstantinos GeorgiouAnders D. BørglumRichard A. Gatti, Therese Törngren & Qiang Pan-Hammarström. (2015) Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells. Proceedings of the National Academy of Sciences 112:7, pages 2157-2162.
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Robert M. Brosh & Sharon B. Cantor. (2014) Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemia. Frontiers in Genetics 5.
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Min Peng, Jenny Xie, Anna Ucher, Janet Stavnezer & Sharon B Cantor. (2014) Crosstalk between BRCA ‐ F anconi anemia and mismatch repair pathways prevents MSH 2‐dependent aberrant DNA damage responses . The EMBO Journal 33:15, pages 1698-1712.
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Michael P. McCrane, Mark A. Hutchinson, Omer Ad & Steven E. Rokita. (2014) Oxidative Quenching of Quinone Methide Adducts Reveals Transient Products of Reversible Alkylation in Duplex DNA. Chemical Research in Toxicology 27:7, pages 1282-1293.
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Manhong Guo, Venkatasubramanian Vidhyasagar, Hao Ding & Yuliang Wu. (2014) Insight into the Roles of Helicase Motif Ia by Characterizing Fanconi Anemia Group J Protein (FANCJ) Patient Mutations. Journal of Biological Chemistry 289:15, pages 10551-10565.
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Shawna Guillemette, Amy Branagan, Min Peng, Aashana Dhruva, Orlando D. Schärer & Sharon B. Cantor. (2014) FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation. Cancer Research 74:3, pages 932-944.
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Robert M. BroshJr.Jr.. (2013) DNA helicases involved in DNA repair and their roles in cancer. Nature Reviews Cancer 13:8, pages 542-558.
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