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Article

Transcription Factor Glis3, a Novel Critical Player in the Regulation of Pancreatic β-Cell Development and Insulin Gene Expression

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Pages 6366-6379 | Received 17 Sep 2009, Accepted 25 Sep 2009, Published online: 21 Mar 2023

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Yue Wu, Jun Zhou & Yunfan Yang. (2023) Peripheral and central control of obesity by primary cilia. Journal of Genetics and Genomics.
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David S. Lorberbaum, Dylan Sarbaugh & Lori Sussel. (2022) Leveraging the strengths of mice, human stem cells, and organoids to model pancreas development and diabetes. Frontiers in Endocrinology 13.
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Bushra Memon & Essam M Abdelalim. (2022) Toward Precision Medicine with Human Pluripotent Stem Cells for Diabetes. Stem Cells Translational Medicine 11:7, pages 704-714.
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Mario Enrique Alvarez Fallas, Sergio Pedraza-Arevalo, Ana-Maria Cujba, Teodora Manea, Christopher Lambert, Rosario Morrugares & Rocio Sancho. (2021) Stem/progenitor cells in normal physiology and disease of the pancreas. Molecular and Cellular Endocrinology 538, pages 111459.
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Eliana Toren, KaLia S. Burnette, Ronadip R. Banerjee, Chad S. Hunter & Hubert M. Tse. (2021) Partners in Crime: Beta-Cells and Autoimmune Responses Complicit in Type 1 Diabetes Pathogenesis. Frontiers in Immunology 12.
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Guilherme Coutinho Kullmann Duarte, Tais Silveira Assmann, Bianca Marmontel de Souza & Daisy Crispim. (2021) Polymorphisms in GLIS3 and susceptibility to diabetes mellitus: A systematic review and meta-analysis. Meta Gene 29, pages 100898.
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Federica Marelli, Giuditta Rurale & Luca Persani. (2021) From Endoderm to Progenitors: An Update on the Early Steps of Thyroid Morphogenesis in the Zebrafish. Frontiers in Endocrinology 12.
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Shira London, Elisa De Franco, Ghadir Elias-Assad, Marie Noufi Barhoum, Clari Felszer, Marina Paniakov, Scott A. Weiner & Yardena Tenenbaum-Rakover. (2021) Case Report: Neonatal Diabetes Mellitus Caused by a Novel GLIS3 Mutation in Twins. Frontiers in Endocrinology 12.
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Arístides López-Márquez, Carlos Carrasco-López, Celia Fernández-Méndez & Pilar Santisteban. (2021) Unraveling the Complex Interplay Between Transcription Factors and Signaling Molecules in Thyroid Differentiation and Function, From Embryos to Adults. Frontiers in Endocrinology 12.
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Ildem Akerman, Miguel Angel Maestro, Elisa De Franco, Vanessa Grau, Sarah Flanagan, Javier García-Hurtado, Gerhard Mittler, Philippe Ravassard, Lorenzo Piemonti, Sian Ellard, Andrew T. Hattersley & Jorge Ferrer. (2021) Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene. Cell Reports 35:2, pages 108981.
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Maria Inês Alvelos, Mirko Brüggemann, FX Reymond Sutandy, Jonàs Juan-Mateu, Maikel Luis Colli, Anke Busch, Miguel Lopes, Ângela Castela, Annemieke Aartsma-Rus, Julian König, Kathi Zarnack & Décio L Eizirik. (2020) The RNA-binding profile of the splicing factor SRSF6 in immortalized human pancreatic β-cells. Life Science Alliance 4:3, pages e202000825.
Crossref
Jian-luo Zhang, Cun-li Zhang, Bai-gang Zhou, Bo-yi Lei, Bo Zhang & Hong-tao Yang. (2020) Association study of the functional variants of the GLIS3 gene with risk of knee osteoarthritis. Clinical Rheumatology 40:3, pages 1039-1046.
Crossref
Essam M. Abdelalim. (2020) Modeling different types of diabetes using human pluripotent stem cells. Cellular and Molecular Life Sciences 78:6, pages 2459-2483.
Crossref
Stephanie Bourgeois, Toshiaki Sawatani, Annelore Van Mulders, Nico De Leu, Yves Heremans, Harry Heimberg, Miriam Cnop & Willem Staels. (2021) Towards a Functional Cure for Diabetes Using Stem Cell-Derived Beta Cells: Are We There Yet?. Cells 10:1, pages 191.
Crossref
Itziar González-Moro & Izortze Santin. 2021. Pancreatic ß-Cell Biology in Health and Disease. Pancreatic ß-Cell Biology in Health and Disease 325 355 .
Laura Sanchez Caballero, Vyron Gorgogietas, Maria Nicol Arroyo & Mariana Igoillo-Esteve. 2021. Pancreatic ß-Cell Biology in Health and Disease. Pancreatic ß-Cell Biology in Health and Disease 139 256 .
David W. Scoville, Hong Soon Kang & Anton M. Jetten. (2020) Transcription factor GLIS3: Critical roles in thyroid hormone biosynthesis, hypothyroidism, pancreatic beta cells and diabetes. Pharmacology & Therapeutics 215, pages 107632.
Crossref
Thais Basili, Higinio Dopeso, Sarah H. Kim, Lorenzo Ferrando, Fresia Pareja, Arnaud Cruz Paula, Edaise M. Silva, Anthe Stylianou, Ana Maroldi, Caterina Marchiò, Brian P. Rubin, Mauro Papotti, Britta Weigelt, Carlos Gil Moreira Ferreira, José Roberto Lapa e Silva & Jorge S. Reis‐Filho. (2020) Oncogenic properties and signaling basis of the PAX8‐GLIS3 fusion gene . International Journal of Cancer 147:8, pages 2253-2264.
Crossref
Dario Iafusco, Angela Zanfardino, Riccardo Bonfanti, Ivana Rabbone, Nadia Tinto, Fernanda Iafusco, Serena Meola, Maria F. Gicchino, Gulsum Ozen, Francesca Casaburo, Alessia Piscopo, Emanuele Miraglia Del Giudice & Fabrizio Barbetti. (2020) Congenital diabetes mellitus. Minerva Pediatrica 72:4.
Crossref
Nur Shabrina Amirruddin, Blaise Su Jun Low, Kok Onn Lee, E Shyong Tai & Adrian Kee Keong Teo. (2020) New insights into human beta cell biology using human pluripotent stem cells. Seminars in Cell & Developmental Biology 103, pages 31-40.
Crossref
Haipeng Pang, Shuoming Luo, Gan Huang, Ying Xia, Zhiguo Xie & Zhiguang Zhou. (2020) Advances in Knowledge of Candidate Genes Acting at the Beta-Cell Level in the Pathogenesis of T1DM. Frontiers in Endocrinology 11.
Crossref
Giuditta RuraleFederica MarelliPaolo DuminucoLuca Persani. (2020) Glis3 as a Critical Regulator of Thyroid Primordium Specification . Thyroid 30:2, pages 277-289.
Crossref
Yuuri Yasuoka, Masahito Matsumoto, Ken Yagi & Yasushi Okazaki. (2020) Evolutionary History of GLIS Genes Illuminates Their Roles in Cell Reprograming and Ciliogenesis. Molecular Biology and Evolution 37:1, pages 100-109.
Crossref
David S. Lorberbaum, Fiona M. Docherty & Lori Sussel. 2020. Animal Models of Human Birth Defects. Animal Models of Human Birth Defects 65 85 .
Shomoita Sayed & A. H. M. Nurun Nabi. 2021. Diabetes: from Research to Clinical Practice. Diabetes: from Research to Clinical Practice 457 498 .
Bjoern Gaertner, Andrea C. Carrano & Maike Sander. (2019) Human stem cell models: lessons for pancreatic development and disease. Genes & Development 33:21-22, pages 1475-1490.
Crossref
Jacob R. Tremblay, Kasandra Lopez & Hsun Teresa Ku. (2019) A GLIS3–CD133–WNT-signaling axis regulates the self-renewal of adult murine pancreatic progenitor-like cells in colonies and organoids. Journal of Biological Chemistry 294:45, pages 16634-16649.
Crossref
Anton M. Jetten. (2019) Emerging Roles of GLI-Similar Krüppel-like Zinc Finger Transcription Factors in Leukemia and Other Cancers. Trends in Cancer 5:9, pages 547-557.
Crossref
Jihua Sun, Christian Theil Have, Mette Hollensted, Niels Grarup, Allan Linneberg, Oluf Pedersen, Jens Steen Nielsen, Jørgen Rungby, Cramer Christensen, Ivan Brandslund, Karsten Kristiansen, Wang Jun, Torben Hansen & Anette P. Gjesing. (2019) Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants. PLOS ONE 14:8, pages e0220805.
Crossref
Victor Navarro-Tableros, Chiara Gai, Yonathan Gomez, Sara Giunti, Chiara Pasquino, Maria Chiara Deregibus, Marta Tapparo, Adriana Pitino, Ciro Tetta, Maria Felice Brizzi, Camillo Ricordi & Giovanni Camussi. (2018) Islet-Like Structures Generated In Vitro from Adult Human Liver Stem Cells Revert Hyperglycemia in Diabetic SCID Mice. Stem Cell Reviews and Reports 15:1, pages 93-111.
Crossref
Giuditta Rurale, Luca Persani & Federica Marelli. (2018) GLIS3 and Thyroid: A Pleiotropic Candidate Gene for Congenital Hypothyroidism. Frontiers in Endocrinology 9.
Crossref
Anton M. Jetten. (2018) GLIS1–3 transcription factors: critical roles in the regulation of multiple physiological processes and diseases. Cellular and Molecular Life Sciences 75:19, pages 3473-3494.
Crossref
Motoyuki Tsuda, Akihisa Fukuda, Nilotpal Roy, Yukiko Hiramatsu, Laura Leonhardt, Nobuyuki Kakiuchi, Kaja Hoyer, Satoshi Ogawa, Norihiro Goto, Kozo Ikuta, Yoshito Kimura, Yoshihide Matsumoto, Yutaka Takada, Takuto Yoshioka, Takahisa Maruno, Yuichi Yamaga, Grace E. Kim, Haruhiko Akiyama, Seishi Ogawa, Christopher V. Wright, Dieter Saur, Kyoichi Takaori, Shinji Uemoto, Matthias Hebrok, Tsutomu Chiba & Hiroshi Seno. (2018) The BRG1/SOX9 axis is critical for acinar cell–derived pancreatic tumorigenesis. Journal of Clinical Investigation 128:8, pages 3475-3489.
Crossref
Sadaf Amin, Brandoch Cook, Ting Zhou, Zaniar Ghazizadeh, Raphael Lis, Tuo Zhang, Mona Khalaj, Miguel Crespo, Manuradhi Perera, Jenny Zhaoying Xiang, Zengrong Zhu, Mark Tomishima, Chengyang Liu, Ali Naji, Todd Evans, Danwei Huangfu & Shuibing Chen. (2018) Discovery of a drug candidate for GLIS3-associated diabetes. Nature Communications 9:1.
Crossref
Tyler M. Hoard, Xiao Ping Yang, Anton M. Jetten & Gary T. ZeRuth. (2018) PIAS-family proteins negatively regulate Glis3 transactivation function through SUMO modification in pancreatic β cells. Heliyon 4:7, pages e00709.
Crossref
Erica K. Ungewitter, Emmi Rotgers, Hong Soon Kang, Kristin Lichti-Kaiser, Leping Li, Sara A. Grimm, Anton M. Jetten & Humphrey H.-C. Yao. (2018) Loss of Glis3 causes dysregulation of retrotransposon silencing and germ cell demise in fetal mouse testis. Scientific Reports 8:1.
Crossref
Sophie Calderari, Massimiliano Ria, Christelle Gérard, Tatiane C. Nogueira, Olatz Villate, Stephan C. Collins, Helen Neil, Nicolas Gervasi, Christophe Hue, Nicolas Suarez-Zamorano, Cécilia Prado, Miriam Cnop, Marie-Thérèse Bihoreau, Pamela J. Kaisaki, Jean-Baptiste Cazier, Cécile Julier, Mark Lathrop, Michel Werner, Decio L. Eizirik & Dominique Gauguier. (2018) Molecular genetics of the transcription factor GLIS3 identifies its dual function in beta cells and neurons. Genomics 110:2, pages 98-111.
Crossref
Maja B.K. Petersen, Carla A.C. Gonçalves, Yung Hae Kim & Anne Grapin-Botton. 2018. Human Embryonic Stem Cells in Development. Human Embryonic Stem Cells in Development 143 190 .
L. Charles Murtaugh, Ondine Cleaver & Raymond J. MacDonald. 2018. Pancreatic Cancer. Pancreatic Cancer 89 145 .
K. A. Alghamdi, A. B. Alsaedi, A. Aljasser, A. Altawil & Naglaa M. Kamal. (2017) Extended clinical features associated with novel Glis3 mutation: a case report. BMC Endocrine Disorders 17:1.
Crossref
Hong Soon Kang, Dhirendra Kumar, Grace Liao, Kristin Lichti-Kaiser, Kevin Gerrish, Xiao-Hui Liao, Samuel Refetoff, Raja Jothi & Anton M. Jetten. (2017) GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation. Journal of Clinical Investigation 127:12, pages 4326-4337.
Crossref
Chon-Kit Chou, Chin-Ju Tang, Han-Lin Chou, Chun-Yen Liu, Ming-Chong Ng, Yu-Ting Chang, Shyng-Shiou F. Yuan, Eing-Mei Tsai & Chien-Chih Chiu. (2017) The Potential Role of Krüppel-Like Zinc-Finger Protein Glis3 in Genetic Diseases and Cancers. Archivum Immunologiae et Therapiae Experimentalis 65:5, pages 381-389.
Crossref
Seo-Young Lee, Hye Bin Noh, Hyeong-Taek Kim, Kang-In Lee & Dong-Youn Hwang. (2017) Glis family proteins are differentially implicated in the cellular reprogramming of human somatic cells. Oncotarget 8:44, pages 77041-77049.
Crossref
Guilherme C. K. Duarte, Tais S. Assmann, Cristine Dieter, Bianca M. de Souza & Daisy Crispim. (2017) GLIS3 rs7020673 and rs10758593 polymorphisms interact in the susceptibility for type 1 diabetes mellitus. Acta Diabetologica 54:9, pages 813-821.
Crossref
Andrea K Steck, Ping Xu, Susan Geyer, Maria J Redondo, Peter Antinozzi, John M Wentworth, Jay Sosenko, Suna Onengut-Gumuscu, Wei-Min Chen, Stephen S Rich & Alberto Pugliese. (2017) Can Non-HLA Single Nucleotide Polymorphisms Help Stratify Risk in TrialNet Relatives at Risk for Type 1 Diabetes?. The Journal of Clinical Endocrinology & Metabolism 102:8, pages 2873-2880.
Crossref
Hjalte List Larsen & Anne Grapin-Botton. (2017) The molecular and morphogenetic basis of pancreas organogenesis. Seminars in Cell & Developmental Biology 66, pages 51-68.
Crossref
Hao-ying Dou, Yuan-yuan Wang, Nan Yang, Ming-li Heng, Xuan Zhou, Huai-en Bu, Fang Xu, Tie-niu Zhao, He Huang & Hong-wu Wang. (2016) Association between genetic variants and characteristic symptoms of type 2 diabetes: A matched case-control study. Chinese Journal of Integrative Medicine 23:6, pages 415-424.
Crossref
P. Dimitri. (2017) The role of GLIS3 in thyroid disease as part of a multisystem disorder. Best Practice & Research Clinical Endocrinology & Metabolism 31:2, pages 175-182.
Crossref
Joachim Størling & Flemming Pociot. (2017) Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis. Genes 8:2, pages 72.
Crossref
Xianjie Wen & Yisheng Yang. (2017) Emerging roles of GLIS3 in neonatal diabetes, type 1 and type 2 diabetes. Journal of Molecular Endocrinology 58:2, pages R73-R85.
Crossref
Yisheng YangSean P. BushXianjie Wen, Wei CaoLawrence Chan. (2017) Differential Gene Dosage Effects of Diabetes-Associated Gene GLIS3 in Pancreatic β Cell Differentiation and Function. Endocrinology 158:1, pages 9-20.
Crossref
James Denvir, Goran Boskovic, Jun Fan, Donald A. Primerano, Jacaline K. Parkman & Jung Han Kim. (2016) Whole genome sequence analysis of the TALLYHO/Jng mouse. BMC Genomics 17:1.
Crossref
Hong Soon Kang, Liang-Yu Chen, Kristin Lichti-Kaiser, Grace Liao, Kevin Gerrish, Carl D. Bortner, Humphrey H.-C. Yao, Edward M. Eddy & Anton M. Jetten. (2016) Transcription Factor GLIS3: A New and Critical Regulator of Postnatal Stages of Mouse Spermatogenesis. Stem Cells 34:11, pages 2772-2783.
Crossref
A. Motterle, C. Sanchez-Parra & R. Regazzi. (2016) Role of long non-coding RNAs in the determination of β-cell identity. Diabetes, Obesity and Metabolism 18, pages 41-50.
Crossref
Paul Dimitri, Elisa De Franco, Abdelhadi M. Habeb, Fatih Gurbuz, Khairya Moussa, Doris Taha, Jerry K. H. Wales, Jacob Hogue, Anne Slavotinek, Ambika Shetty & Meena Balasubramanian. (2016) An emerging, recognizable facial phenotype in association with mutations in GLI-similar 3 ( GLIS3 ) . American Journal of Medical Genetics Part A 170:7, pages 1918-1923.
Crossref
Hong Soon Kang, Yukimasa Takeda, Kilsoo Jeon & Anton M. Jetten. (2016) The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal Cells. PLOS ONE 11:6, pages e0157138.
Crossref
Yisheng YangLawrence Chan. (2016) Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes. Endocrine Reviews 37:3, pages 190-222.
Crossref
Berta Terré, Gabriele Piergiovanni, Sandra Segura‐Bayona, Gabriel Gil‐Gómez, Sameh A Youssef, Camille Stephan‐Otto Attolini, Michaela Wilsch‐Bräuninger, Carole Jung, Ana M Rojas, Marko Marjanović, Philip A Knobel, Lluís Palenzuela, Teresa López‐Rovira, Stephen Forrow, Wieland B Huttner, Miguel A Valverde, Alain de Bruin, Vincenzo Costanzo & Travis H Stracker. (2016) GEMC 1 is a critical regulator of multiciliated cell differentiation . The EMBO Journal 35:9, pages 942-960.
Crossref
Jonàs Juan-Mateu, Olatz Villate & Décio L Eizirik. (2016) MECHANISMS IN ENDOCRINOLOGY: Alternative splicing: the new frontier in diabetes research. European Journal of Endocrinology 174:5, pages R225-R238.
Crossref
James Dooley, Lei Tian, Susann Schonefeldt, Viviane Delghingaro-Augusto, Josselyn E Garcia-Perez, Emanuela Pasciuto, Daniele Di Marino, Edward J Carr, Nikolay Oskolkov, Valeriya Lyssenko, Dean Franckaert, Vasiliki Lagou, Lut Overbergh, Jonathan Vandenbussche, Joke Allemeersch, Genevieve Chabot-Roy, Jane E Dahlstrom, D Ross Laybutt, Nikolai Petrovsky, Luis Socha, Kris Gevaert, Anton M Jetten, Diether Lambrechts, Michelle A Linterman, Chris C Goodnow, Christopher J Nolan, Sylvie Lesage, Susan M Schlenner & Adrian Liston. (2016) Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes. Nature Genetics 48:5, pages 519-527.
Crossref
Elizabeth A. O'Hare, Laura M. Yerges-Armstrong, James A. Perry, Alan R. Shuldiner & Norann A. Zaghloul. (2016) Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of β-Cell Mass Deficits. Molecular Endocrinology 30:4, pages 429-445.
Crossref
Tao Bai, Fan Wang, Nicholas Mellen, Yang ZhengLu Cai. (2016) Diabetic cardiomyopathy: role of the E3 ubiquitin ligase. American Journal of Physiology-Endocrinology and Metabolism 310:7, pages E473-E483.
Crossref
L. Charles Murtaugh, Ondine Cleaver & Raymond J. MacDonald. 2017. Pancreatic Cancer. Pancreatic Cancer 1 57 .
Tina Fløyel, Simranjeet Kaur & Flemming Pociot. (2015) Genes Affecting β-Cell Function in Type 1 Diabetes. Current Diabetes Reports 15:11.
Crossref
David M. Blodgett, Anetta Nowosielska, Shaked Afik, Susanne Pechhold, Anthony J. Cura, Norman J. Kennedy, Soyoung Kim, Alper Kucukural, Roger J. Davis, Sally C. Kent, Dale L. Greiner, Manuel G. Garber, David M. Harlan & Philip diIorio. (2015) Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets. Diabetes 64:9, pages 3172-3181.
Crossref
Anthony I. Romer & Lori Sussel. (2015) Pancreatic islet cell development and regeneration. Current Opinion in Endocrinology, Diabetes & Obesity 22:4, pages 255-264.
Crossref
Laurence A. Lemaire, Joan Goulley, Yung Hae Kim, Solenne Carat, Patrick Jacquemin, Jacques Rougemont, Daniel B. Constam & Anne Grapin-Botton. (2015) Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis. Development 142:5, pages 858-870.
Crossref
Matias G. De Vas, Janel L. Kopp, Claire Heliot, Maike Sander, Silvia Cereghini & Cécile Haumaitre. (2015) Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development 142:5, pages 871-882.
Crossref
Edwin C. Oh, Shivakumar Vasanth & Nicholas Katsanis. (2015) Metabolic Regulation and Energy Homeostasis through the Primary Cilium. Cell Metabolism 21:1, pages 21-31.
Crossref
Eric H. Davidson & Isabelle S. Peter. 2015. Genomic Control Process. Genomic Control Process 133 200 .
S. A. Carter, A. R. Kitching & L. M. Johnstone. (2014) Four pediatric patients with autosomal recessive polycystic kidney disease developed new-onset diabetes after renal transplantation. Pediatric Transplantation 18:7, pages 698-705.
Crossref
Vasumathi Kameswaran & Klaus H. Kaestner. (2014) The Missing lnc(RNA) between the pancreatic β-cell and diabetes. Frontiers in Genetics 5.
Crossref
Hung Ping ShihAllen WangMaike Sander. (2013) Pancreas Organogenesis: From Lineage Determination to Morphogenesis. Annual Review of Cell and Developmental Biology 29:1, pages 81-105.
Crossref
Gary T. ZeRuth, Yukimasa Takeda & Anton M. Jetten. (2013) The Krüppel-Like Protein Gli-Similar 3 (Glis3) Functions as a Key Regulator of Insulin Transcription. Molecular Endocrinology 27:10, pages 1692-1705.
Crossref
Takuya Awata, Hisakuni Yamashita, Susumu Kurihara, Tomoko Morita-Ohkubo, Yumi Miyashita, Shigehiro Katayama, Eiji Kawasaki, Shoichiro Tanaka, Hiroshi Ikegami, Taro Maruyama, Akira Shimada, Kazuma Takahashi, Yumiko Kawabata, Tetsuro Kobayashi, Nao Nishida & Yoriko Mawatari. (2013) A low-frequency GLIS3 variant associated with resistance to Japanese type 1 diabetes. Biochemical and Biophysical Research Communications 437:4, pages 521-525.
Crossref
Scott A. Soleimanpour & Doris A. Stoffers. (2013) The pancreatic β cell and type 1 diabetes: innocent bystander or active participant?. Trends in Endocrinology & Metabolism 24:7, pages 324-331.
Crossref
Solomon Afelik & Jan Jensen. (2013) Notch signaling in the pancreas: patterning and cell fate specification. Wiley Interdisciplinary Reviews: Developmental Biology 2:4, pages 531-544.
Crossref
M. O. Goodarzi, X. Guo, J. Cui, M. R. Jones, T. Haritunians, A. H. Xiang, Y.-D. I. Chen, K. D. Taylor, T. A. Buchanan, W. A. Hsueh, L. J. Raffel & J. I. Rotter. (2013) Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance. Diabetologia 56:6, pages 1282-1290.
Crossref
Tatiane C. Nogueira, Flavia M. Paula, Olatz Villate, Maikel L. Colli, Rodrigo F. Moura, Daniel A. Cunha, Lorella Marselli, Piero Marchetti, Miriam Cnop, Cécile Julier & Decio L. Eizirik. (2013) GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim. PLoS Genetics 9:5, pages e1003532.
Crossref
H. Efsun Arda, Cecil M. Benitez & Seung K. Kim. (2013) Gene Regulatory Networks Governing Pancreas Development. Developmental Cell 25:1, pages 5-13.
Crossref
Lu Jie, Wang Fan, Dai Weiqi, Zhou Yingqun, Xu Ling, Shen Miao, Cheng Ping & Guo Chuanyong. (2013) The Hippo-Yes Association Protein Pathway in Liver Cancer. Gastroenterology Research and Practice 2013, pages 1-7.
Crossref
Yisheng Yang, Benny Hung‐Junn Chang & Lawrence Chan. (2012) Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults. EMBO Molecular Medicine 5:1, pages 92-104.
Crossref
Yoon Shin Cho, Jong-Young Lee, Kyong Soo Park & Chu Won Nho. (2012) Genetics of Type 2 Diabetes in East Asian Populations. Current Diabetes Reports 12:6, pages 686-696.
Crossref
Yong-Sik Kim, Hong Soon Kang, Yukimasa Takeda, Lisa Hom, Ho-Yeon Song, Jan Jensen & Anton M. Jetten. (2012) Glis3 regulates neurogenin 3 expression in pancreatic β-cells and interacts with its activator, Hnf6. Molecules and Cells 34:2, pages 193-200.
Crossref
Abdella M. Habib, Paul Richards, Lynne S. Cairns, Gareth J. Rogers, Christopher A. M. Bannon, Helen E. Parker, Tom C. E. Morley, Giles S. H. Yeo, Frank Reimann & Fiona M. Gribble. (2012) Overlap of Endocrine Hormone Expression in the Mouse Intestine Revealed by Transcriptional Profiling and Flow Cytometry. Endocrinology 153:7, pages 3054-3065.
Crossref
Yoon Shin Cho, Chien-Hsiun Chen, Cheng Hu, Jirong Long, Rick Twee Hee Ong, Xueling Sim, Fumihiko Takeuchi, Ying Wu, Min Jin Go, Toshimasa Yamauchi, Yi-Cheng Chang, Soo Heon Kwak, Ronald C W Ma, Ken Yamamoto, Linda S Adair, Tin Aung, Qiuyin Cai, Li-Ching Chang, Yuan-Tsong Chen, Yutang Gao, Frank B Hu, Hyung-Lae Kim, Sangsoo Kim, Young Jin Kim, Jeannette Jen-Mai Lee, Nanette R Lee, Yun Li, Jian Jun Liu, Wei Lu, Jiro Nakamura, Eitaro Nakashima, Daniel Peng-Keat Ng, Wan Ting Tay, Fuu-Jen Tsai, Tien Yin Wong, Mitsuhiro Yokota, Wei Zheng, Rong Zhang, Congrong Wang, Wing Yee So, Keizo Ohnaka, Hiroshi Ikegami, Kazuo Hara, Young Min Cho, Nam H Cho, Tien-Jyun Chang, Yuqian Bao, Åsa K Hedman, Andrew P Morris, Mark I McCarthy, Ryoichi Takayanagi, Kyong Soo Park, Weiping Jia, Lee-Ming Chuang, Juliana C N Chan, Shiro Maeda, Takashi Kadowaki, Jong-Young Lee, Jer-Yuarn Wu, Yik Ying Teo, E Shyong Tai, Xiao Ou Shu, Karen L Mohlke, Norihiro Kato, Bok-Ghee Han & Mark Seielstad. (2011) Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nature Genetics 44:1, pages 67-72.
Crossref
Kristin Lichti-Kaiser, Gary ZeRuth, Hong Soon Kang, Shivakumar Vasanth & Anton M. Jetten. 2012. Hedgehog Signaling. Hedgehog Signaling 141 171 .
Y. Yang, B. H-J. Chang, V. Yechoor, W. Chen, L. Li, M.-J. Tsai & L. Chan. (2011) The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice. Diabetologia 54:10, pages 2595-2605.
Crossref
Simon D. Rees, M. Zafar I. Hydrie, J. Paul O'Hare, Sudhesh Kumar, A. Samad Shera, Abdul Basit, Anthony H. Barnett & M. Ann Kelly. (2011) Effects of 16 Genetic Variants on Fasting Glucose and Type 2 Diabetes in South Asians: ADCY5 and GLIS3 Variants May Predispose to Type 2 Diabetes. PLoS ONE 6:9, pages e24710.
Crossref
Hong Soon KangKyoko OkamotoYukimasa TakedaJu Youn BeakKevin GerrishCarl D. Bortner, Laura M. DeGraffTaira Wada, Wen Xie & Anton M. Jetten. (2011) Transcriptional profiling reveals a role for RORα in regulating gene expression in obesity-associated inflammation and hepatic steatosis. Physiological Genomics 43:13, pages 818-828.
Crossref
Chen Liu, Huaixing Li, Lu Qi, Ruth J. F. Loos, Qibin Qi, Ling Lu, Wei Gan & Xu Lin. (2011) Variants in GLIS3 and CRY2 Are Associated with Type 2 Diabetes and Impaired Fasting Glucose in Chinese Hans. PLoS ONE 6:6, pages e21464.
Crossref
Gary T. ZeRuth, Xiao-Ping Yang & Anton M. Jetten. (2011) Modulation of the Transactivation Function and Stability of Krüppel-like Zinc Finger Protein Gli-similar 3 (Glis3) by Suppressor of Fused. Journal of Biological Chemistry 286:25, pages 22077-22089.
Crossref
Oscar Rubio-Cabezas, Tomasz Klupa & Maciej T. Malecki. (2011) Permanent neonatal diabetes mellitus - the importance of diabetes differential diagnosis in neonates and infants. European Journal of Clinical Investigation 41:3, pages 323-333.
Crossref
Shivakumar Vasanth, Gary ZeRuth, Hong Soon Kang & Anton M. Jetten. (2011) Identification of Nuclear Localization, DNA Binding, and Transactivating Mechanisms of Krüppel-like Zinc Finger Protein Gli-Similar 2 (Glis2). Journal of Biological Chemistry 286:6, pages 4749-4759.
Crossref
Caroline Bolmeson, Jonathan L.S. Esguerra, Albert Salehi, Dina Speidel, Lena Eliasson & Corrado M. Cilio. (2011) Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects. Biochemical and Biophysical Research Communications 404:1, pages 16-22.
Crossref
Hisashi Hashimoto & Yuko Wakamatsu. 2011. Regenerative Nephrology. Regenerative Nephrology 3 17 .
Xiaofeng Zhou & Jeffrey L. Platt. 2011. Cell Fusion in Health and Disease. Cell Fusion in Health and Disease 33 64 .
Intza GarinEmma L. EdghillIldem AkermanOscar Rubio-CabezasItxaso RicaJonathan M. LockeMiguel Angel MaestroAdnan AlshaikhRuveyde BundakGabriel del CastilloAsma DeebDorothee DeissJuan M. FernandezKoumudi GodboleKhalid HussainMichele O’ConnellThomasz KlupaStanislava KolouskovaFauzia MohsinKusiel PerlmanZdenek SumnikJose M. RialEstibaliz Ugarte, Thiruvengadam Vasanthi, Karen JohnstoneSarah E. FlanaganRosa MartínezCarlos CastañoAnn-Marie PatchEduardo Fernández-RebolloKlemens RaileNoel MorganLorna W. HarriesLuis CastañoSian EllardJorge FerrerGuiomar Perez de NanclaresAndrew T. Hattersley. (2010) Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis . Proceedings of the National Academy of Sciences 107:7, pages 3105-3110.
Crossref

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