Advanced search
Publication Cover
Molecular and Cellular Biology Volume 30, 2010 - Issue 14
Submit an article Journal homepage
23
Views
25
CrossRef citations to date
0
Altmetric
Article

Rac1 Is Essential for Basement Membrane-Dependent Epiblast Survival

Xiaowen He1 Departments of Surgery
,
Jie Liu1 Departments of Surgery
,
Yanmei Qi1 Departments of Surgery
,
Cord Brakebusch2 BRIC, University of Copenhagen, Copenhagen, Denmark
,
Anna Chrostek-Grashoff3 Cardiovascular Research Center, University of Virginia, Charlottesville, Virginia22904
,
David Edgar4 Department of Human Anatomy and Cell Biology, University of Liverpool, LiverpoolL69 3BX, United Kingdom
,
Peter D. Yurchenco5 Pathology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, New Jersey08903
,
Siobhan A. Corbett1 Departments of Surgery
,
Stephen F. Lowry1 Departments of Surgery
,
Alan M. Graham1 Departments of Surgery
,
Yaling Han6 Shenyang Northern Hospital, Shenyang110016, China
&
Shaohua Li1 Departments of SurgeryCorrespondence[email protected]
 show all
Pages 3569-3581 | Received 14 Oct 2009, Accepted 12 Apr 2010, Published online: 20 Mar 2023

Citations (25)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Philippe M Duquette & Nathalie Lamarche-Vane. (2014) Rho GTPases in embryonic development. Small GTPases 5:2.
Read now

Articles from other publishers (24)

Emily J. Koubek & Lorraine C. Santy. (2022) Actin Up: An Overview of the Rac GEF Dock1/Dock180 and Its Role in Cytoskeleton Rearrangement. Cells 11:22, pages 3565.
Crossref
Gabrielle Keb, Joshua Ferrell, Kaylyn R. Scanlon, Travis J. Jewett & Kenneth A. Fields. (2021) Chlamydia trachomatis TmeA Directly Activates N-WASP To Promote Actin Polymerization and Functions Synergistically with TarP during Invasion. mBio 12:1.
Crossref
Thobela Louis Tyasi, Xue Sun, Xuesong Shan, Simushi Liswaniso, Ignatius Musenge Chimbaka, Ning Qin & Rifu Xu. (2020) Effects of RAC1 on Proliferation of Hen Ovarian Prehierarchical Follicle Granulosa Cells. Animals 10:9, pages 1589.
Crossref
Xujuan Sun, Shuqing Liu, Jinxia Wang, Bin Wei, Chunmei Guo, Chen Chen & Ming-Zhong Sun. (2018) Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-RAC1 integrin and MEK-ERK pathways. Cell Death & Disease 9:6.
Crossref
Shouli Wang, Zhao Yin, Bei Zhao, Yanmei Qi, Jie Liu, Saum A. Rahimi, Leonard Y. Lee & Shaohua Li. (2017) Microgravity simulation activates Cdc42 via Rap1GDS1 to promote vascular branch morphogenesis during vasculogenesis. Stem Cell Research 25, pages 157-165.
Crossref
Sudha Rajderkar, Christopher Panaretos & Vesa Kaartinen. (2017) Trim33 regulates early maturation of mouse embryoid bodies in vitro. Biochemistry and Biophysics Reports 12, pages 185-192.
Crossref
L. T. Nguyen, A. Reverter, A. Cánovas, B. Venus, A. Islas-Trejo, L. R. Porto-Neto, S. A. Lehnert, J. F. Medrano, S. S. Moore & M. R. S. Fortes. (2017) Global differential gene expression in the pituitary gland and the ovaries of pre- and postpubertal Brahman heifers1. Journal of Animal Science 95:2, pages 599-615.
Crossref
Shaohua Li, Yanmei Qi, Karen McKee, Jie Liu, June Hsu & Peter D. Yurchenco. (2017) Integrin and dystroglycan compensate each other to mediate laminin-dependent basement membrane assembly and epiblast polarization. Matrix Biology 57-58, pages 272-284.
Crossref
Lihua Zhao, Xinhua Du, Kun Huang, Tuo Zhang, Zhen Teng, Wanbao Niu, Chao Wang & Guoliang Xia. (2016) Rac1 modulates the formation of primordial follicles by facilitating STAT3-directed Jagged1, GDF9 and BMP15 transcription in mice. Scientific Reports 6:1.
Crossref
Cen Zhang, Juan Liu, Yuhan Zhao, Xuetian Yue, Yu Zhu, Xiaolong Wang, Hao Wu, Felix Blanco, Shaohua Li, Gyan Bhanot, Bruce G Haffty, Wenwei Hu & Zhaohui Feng. (2016) Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis. eLife 5.
Crossref
Christine Hofstetter, Justyna M. Kampka, Sascha Huppertz, Heike Weber, Andreas Schlosser, Albrecht M. Müller & Matthias Becker. (2016) Inhibition of KDM6 activity during murine ES cell differentiation induces DNA damage. Journal of Cell Science.
Crossref
Y Qi, J Liu, S Saadat, X Tian, Y Han, G-H Fong, P P Pandolfi, L Y Lee & S Li. (2014) PTEN induces apoptosis and cavitation via HIF-2-dependent Bnip3 upregulation during epithelial lumen formation. Cell Death & Differentiation 22:5, pages 875-884.
Crossref
Kathrin Schäker, Susanne Bartsch, Christian Patry, Sandra J. Stoll, Jan-Luuk Hillebrands, Thomas Wieland & Jens Kroll. (2015) The Bipartite Rac1 Guanine Nucleotide Exchange Factor Engulfment and Cell Motility 1/Dedicator of Cytokinesis 180 (Elmo1/Dock180) Protects Endothelial Cells from Apoptosis in Blood Vessel Development. Journal of Biological Chemistry 290:10, pages 6408-6418.
Crossref
J. Goldufsky, S. Wood, B. Hajihossainlou, T. Rehman, O. Majdobeh, H. L. Kaufman, C. E. Ruby & S. H. Shafikhani. (2015) Pseudomonas aeruginosa exotoxin T induces potent cytotoxicity against a variety of murine and human cancer cell lines. Journal of Medical Microbiology 64:Pt_2, pages 164-173.
Crossref
Joe Goldufsky, Stephen Wood, Behnam Hajihossainlou, Tooba Rehman, Omar Majdobeh, Howard L. Kaufman, Carl E. Ruby & Sasha H. Shafikhani. (2015) Pseudomonas aeruginosa exotoxin T induces potent cytotoxicity against a variety of murine and human cancer cell lines. Journal of Medical Microbiology 64:2, pages 164-173.
Crossref
Radwan Abu-Issa. (2015) Rac1 modulates cardiomyocyte adhesion during mouse embryonic development. Biochemical and Biophysical Research Communications 456:4, pages 847-852.
Crossref
Ivan Bedzhov, Sarah J. L. Graham, Chuen Yan Leung & Magdalena Zernicka-Goetz. (2014) Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo. Philosophical Transactions of the Royal Society B: Biological Sciences 369:1657, pages 20130538.
Crossref
H Bagci, M Laurin, J Huber, W J Muller & J-F Côté. (2014) Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling. Cell Death & Disease 5:8, pages e1375-e1375.
Crossref
Xiaoling Fu, Meng Xu, Jie Liu, Yanmei Qi, Shaohua Li & Hongjun Wang. (2014) Regulation of migratory activity of human keratinocytes by topography of multiscale collagen-containing nanofibrous matrices. Biomaterials 35:5, pages 1496-1506.
Crossref
Li Rong, Jie Liu, Yanmei Qi, Alan M. Graham, Michael S. Parmacek & Shaohua Li. (2012) GATA-6 promotes cell survival by up-regulating BMP-2 expression during embryonic stem cell differentiation. Molecular Biology of the Cell 23:18, pages 3754-3763.
Crossref
Esben Pedersen & Cord Brakebusch. (2012) Rho GTPase function in development: How in vivo models change our view. Experimental Cell Research 318:14, pages 1779-1787.
Crossref
Yanmei Qi, Xiaoxiang Tian, Jie Liu, Yaling Han, Alan M. Graham, M. Celeste Simon, Josef M. Penninger, Peter Carmeliet & Shaohua Li. (2012) Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis. Journal of Cell Biology 198:1, pages 103-114.
Crossref
Isabelle Migeotte, Joaquim Grego-Bessa & Kathryn V. Anderson. (2011) Rac1 mediates morphogenetic responses to intercellular signals in the gastrulating mouse embryo. Development 138:14, pages 3011-3020.
Crossref
Masatoshi Ohgushi & Yoshiki Sasai. (2011) Lonely death dance of human pluripotent stem cells: ROCKing between metastable cell states. Trends in Cell Biology 21:5, pages 274-282.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.