100
Views
73
CrossRef citations to date
0
Altmetric
Article

The Mouse Polyubiquitin Gene Ubb Is Essential for Meiotic Progression

, , , , , , , , , , & show all
Pages 1136-1146 | Received 27 Aug 2007, Accepted 12 Nov 2007, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Yiqun Ji, Jialu Yao, Yunxiao Zhao, Juping Zhai, Zhen Weng & Yang He. (2020) Extracellular ubiquitin levels are increased in coronary heart disease and associated with the severity of the disease. Scandinavian Journal of Clinical and Laboratory Investigation 80:3, pages 256-264.
Read now

Articles from other publishers (71)

Ban Sato, Jiwoo Kim, Kazunori Morohoshi, Woojin Kang, Kenji Miyado, Fuminori Tsuruta, Natsuko Kawano & Tomoki Chiba. (2023) Proteasome-Associated Proteins, PA200 and ECPAS, Are Essential for Murine Spermatogenesis. Biomolecules 13:4, pages 586.
Crossref
Shan Huang, Yingting Huang, Shan Li & Yu He. (2022) Chromosome 17 translocation affects sperm morphology: Two case studies and literature review. Andrologia 54:11.
Crossref
Lixia Zhu, Qiyu Yang, Huizi Jin, Juepu Zhou, Meng Wang, Liu Yang, Zhou Li, Kun Qian & Lei Jin. (2022) Oocyte phenotype, genetic diagnosis, and clinical outcome in case of patients with oocyte maturation arrest. Frontiers in Endocrinology 13.
Crossref
Safak Hatirnaz, Ebru Hatirnaz, Samettin Çelik, Canan Soyer Çalışkan, Andrea Tinelli, Antonio Malvasi, Radmila Sparic, Domenico Baldini, Michael Stark & Michael H. Dahan. (2022) Unraveling the Puzzle: Oocyte Maturation Abnormalities (OMAS). Diagnostics 12:10, pages 2501.
Crossref
Iván Hernández-Caravaca, Andrés Cabañas, Rebeca López-Úbeda, Leopoldo González-Brusi, Ascensión Guillén-Martínez, Mª José Izquierdo-Rico, Mª Nieves Muñoz-Rodríguez, Manuel Avilés & Mª Jesús Ruiz García. (2022) Analysis of Minor Proteins Present in Breast Milk by Using WGA Lectin. Children 9:7, pages 1084.
Crossref
Farrah El-Saafin, Didier Devys, Steven A. Johnsen, Stéphane D. Vincent & László Tora. (2022) SAGA-Dependent Histone H2Bub1 Deubiquitination Is Essential for Cellular Ubiquitin Balance during Embryonic Development. International Journal of Molecular Sciences 23:13, pages 7459.
Crossref
Shan Huang, Huiling Wu, Yunwei Qi, Liqiang Wei, Xiaodan Lv & Yu He. (2022) Case Report: Balanced Reciprocal Translocation t (17; 22) (p11.2; q11.2) and 10q23.31 Microduplication in an Infertile Male Patient Suffering From Teratozoospermia. Frontiers in Genetics 13.
Crossref
Xiaoyue Ding, Li Cao, Yu Zheng, Xu Zhou, Xiaofang He, Shixia Xu & Wenhua Ren. (2021) Insights into the Evolution of Spermatogenesis-Related Ubiquitin–Proteasome System Genes in Abdominal Testicular Laurasiatherians. Genes 12:11, pages 1780.
Crossref
Peihong Lin, Xuedan Lai, Ling Wu, Wei Liu, Shiqiang Lin & Jianwen Ye. (2021) Network analysis reveals important genes in human placenta. Journal of Obstetrics and Gynaecology Research 47:8, pages 2607-2615.
Crossref
Bitnara Han, Byung-Kwon Jung, So-Hyun Park, Kyu Jin Song, Muhammad Ayaz Anwar, Kwon-Yul Ryu & Kwang Pyo Kim. (2021) Polyubiquitin gene Ubb is required for upregulation of Piwi protein level during mouse testis development. Cell Death Discovery 7:1.
Crossref
Seung-Woo Han, Byung-Kwon Jung & Kwon-Yul Ryu. (2021) Regulation of polyubiquitin genes to meet cellular ubiquitin requirement. BMB Reports 54:4, pages 189-195.
Crossref
Shenae L. Cafe, Brett Nixon, Heath Ecroyd, Jacinta H. Martin, David A. Skerrett-Byrne & Elizabeth G. Bromfield. (2021) Proteostasis in the Male and Female Germline: A New Outlook on the Maintenance of Reproductive Health. Frontiers in Cell and Developmental Biology 9.
Crossref
Cai-Xia Yang, Zhi-Qiang Song, Surui Pei, Xiao-Xia Yu, Jia-Kun Miao, Hao Liang, Yi-Liang Miao & Zhi-Qiang Du. (2020) Single cell RNA-seq reveals molecular pathways altered by 7, 12-dimethylbenz[a]anthracene treatment on pig oocytes. Theriogenology 157, pages 449-457.
Crossref
Madeline Musaus, Shaghayegh Navabpour & Timothy J. Jarome. (2020) The diversity of linkage-specific polyubiquitin chains and their role in synaptic plasticity and memory formation. Neurobiology of Learning and Memory 174, pages 107286.
Crossref
Chul-Woo Park, Jin-Sil Bae & Kwon-Yul Ryu. (2020) Simultaneous Disruption of Both Polyubiquitin Genes Affects Proteasome Function and Decreases Cellular Proliferation. Cell Biochemistry and Biophysics 78:3, pages 321-329.
Crossref
Miao Li, Haiwei Feng, Zexiong Lin, Jiahuan Zheng, Dongteng Liu, Rui Guo, Junshi Li, Raymond H.W. Li, Ernest H.Y. Ng, Michael S.Y. Huen, P. Jeremy Wang, William S.B. Yeung & Kui Liu. (2020) The novel male meiosis recombination regulator coordinates the progression of meiosis prophase I. Journal of Genetics and Genomics 47:8, pages 451-465.
Crossref
Liya Zhu, Han Cheng, Guoqing Peng, Shuansuo Wang, Zhiguo Zhang, Erdong Ni, Xiangdong Fu, Chuxiong Zhuang, Zexian Liu & Hai Zhou. (2020) Ubiquitinome Profiling Reveals the Landscape of Ubiquitination Regulation in Rice Young Panicles. Genomics, Proteomics & Bioinformatics 18:3, pages 305-320.
Crossref
Chul-Woo Park, Byung-Kwon Jung & Kwon-Yul Ryu. (2020) Disruption of the polyubiquitin gene Ubb reduces the self-renewal capacity of neural stem cells. Biochemical and Biophysical Research Communications 527:2, pages 372-378.
Crossref
Xiuli Xu, Yuge Tan, Haiguang Mao, Honghua Liu, Xinyang Dong & Zhaozheng Yin. (2020) Analysis of Long Noncoding RNA and mRNA Expression Profiles of Testes with High and Low Sperm Motility in Domestic Pigeons (Columba livia). Genes 11:4, pages 349.
Crossref
Marzia Bianchi, Rita Crinelli, Elisa Giacomini, Elisa Carloni, Lucia Radici, Emanuele-Salvatore Scarpa, Filippo Tasini & Mauro Magnani. (2019) A negative feedback mechanism links UBC gene expression to ubiquitin levels by affecting RNA splicing rather than transcription. Scientific Reports 9:1.
Crossref
Yun-Seok Choi, Sarah A. Bollinger, Luisa F. Prada, Francesco Scavone, Tingting Yao & Robert E. Cohen. (2019) High-affinity free ubiquitin sensors for quantifying ubiquitin homeostasis and deubiquitination. Nature Methods 16:8, pages 771-777.
Crossref
Seung-Woo Han, Byung-Kwon Jung, So-Hyun Park & Kwon-Yul Ryu. (2019) Reversible Regulation of Polyubiquitin Gene UBC via Modified Inducible CRISPR/Cas9 System. International Journal of Molecular Sciences 20:13, pages 3168.
Crossref
Daehan Lim, Chul-Woo Park, Kwon-Yul Ryu & Hyewon Chung. (2019) Disruption of the polyubiquitin gene Ubb causes retinal degeneration in mice. Biochemical and Biophysical Research Communications 513:1, pages 35-40.
Crossref
D. Toliczenko-Bernatowicz, E. Matuszczak, M. Tylicka, A. Sankiewicz, M. Komarowska, E. Gorodkiewicz, W. Debek & A. Hermanowicz. (2018) 20S proteasome in the blood plasma of boys with cryptorchidism. Journal of Endocrinological Investigation 41:9, pages 1103-1106.
Crossref
Joshua T. Yuan, Daniel M. Gatti, Vivek M. Philip, Steven Kasparek, Andrew M. Kreuzman, Benjamin Mansky, Kayvon Sharif, Dominik Taterra, Walter M. Taylor, Mary Thomas, Jeremy O. Ward, Andrew Holmes, Elissa J. Chesler & Clarissa C. Parker. (2018) Genome-wide association for testis weight in the diversity outbred mouse population. Mammalian Genome 29:5-6, pages 310-324.
Crossref
Marie Christou‐Kent, Zine‐Eddine Kherraf, Amir Amiri‐Yekta, Emilie Le Blévec, Thomas Karaouzène, Béatrice Conne, Jessica Escoffier, Said Assou, Audrey Guttin, Emeline Lambert, Guillaume Martinez, Magalie Boguenet, Selima Fourati Ben Mustapha, Isabelle Cedrin Durnerin, Lazhar Halouani, Ouafi Marrakchi, Mounir Makni, Habib Latrous, Mahmoud Kharouf, Charles Coutton, Nicolas Thierry‐Mieg, Serge Nef, Serge P Bottari, Raoudha Zouari, Jean Paul Issartel, Pierre F Ray & Christophe Arnoult. (2018) PATL 2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice . EMBO Molecular Medicine 10:5.
Crossref
Sora Lee, Jessica M Tumolo, Aaron C Ehlinger, Kristin K Jernigan, Susan J Qualls-Histed, Pi-Chiang Hsu, W Hayes McDonald, Walter J Chazin & Jason A MacGurn. (2017) Ubiquitin turnover and endocytic trafficking in yeast are regulated by Ser57 phosphorylation of ubiquitin. eLife 6.
Crossref
Alexia T. Kedves, Scott Gleim, Xiaoyou Liang, Dennis M. Bonal, Frederic Sigoillot, Fred Harbinski, Sneha Sanghavi, Christina Benander, Elizabeth George, Prafulla C. Gokhale, Quang-De Nguyen, Paul T. Kirschmeier, Robert J. Distel, Jeremy Jenkins, Michael S. Goldberg & William C. Forrester. (2017) Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C. Journal of Clinical Investigation 127:12, pages 4554-4568.
Crossref
Botond Penke, Ferenc Bogár & Lívia Fülöp. (2017) β-Amyloid and the Pathomechanisms of Alzheimer’s Disease: A Comprehensive View. Molecules 22:10, pages 1692.
Crossref
Yuanlei Chen, Chao Qi, Liqun Xia & Gonghui Li. (2017) Identification of novel genetic etiology and key molecular pathways for seminoma via network-based studies. International Journal of Oncology 51:4, pages 1280-1290.
Crossref
Rita Gemayel, Yudi Yang, Maria C. Dzialo, Jacek Kominek, Jakob Vowinckel, Veerle Saels, Leen Van Huffel, Elisa van der Zande, Markus Ralser, Jan Steensels, Karin Voordeckers & Kevin J. Verstrepen. (2017) Variable repeats in the eukaryotic polyubiquitin gene ubi4 modulate proteostasis and stress survival. Nature Communications 8:1.
Crossref
Kasane Kishi, Aya Uchida, Hinako M Takase, Hitomi Suzuki, Masamichi Kurohmaru, Naoki Tsunekawa, Masami Kanai-Azuma, Stephen A Wood & Yoshiakira Kanai. (2017) Spermatogonial deubiquitinase USP9X is essential for proper spermatogenesis in mice. Reproduction 154:2, pages 135-143.
Crossref
Hong Peng, Jiao Yang, Guangyi Li, Qing You, Wen Han, Tianrang Li, Daming Gao, Xiaoduo Xie, Byung-Hoon Lee, Juan Du, Jian Hou, Tao Zhang, Hai Rao, Ying Huang, Qinrun Li, Rong Zeng, Lijian Hui, Hongyan Wang, Qin Xia, Xuemin Zhang, Yongning He, Masaaki Komatsu, Ivan Dikic, Daniel Finley & Ronggui Hu. (2017) Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress. Cell Research 27:5, pages 657-674.
Crossref
Jinsoo Ahn, Yoo-Jin Park, Paula Chen, Tae Jin Lee, Young-Jun Jeon, Carlo M. Croce, Yeunsu Suh, Seongsoo Hwang, Woo-Sung Kwon, Myung-Geol Pang, Cheorl-Ho Kim, Sang Suk Lee & Kichoon Lee. (2017) Comparative expression profiling of testis-enriched genes regulated during the development of spermatogonial cells. PLOS ONE 12:4, pages e0175787.
Crossref
Minji Kim & Kwon-Yul Ryu. (2017) Regulation of REST levels overcomes dysregulation of neural stem cell differentiation caused by disruption of polyubiquitin gene Ubb. Biochemical and Biophysical Research Communications 486:1, pages 171-177.
Crossref
Masanori Kobayashi, Shigeru Oshima, Chiaki Maeyashiki, Yoichi Nibe, Kana Otsubo, Yu Matsuzawa, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura & Mamoru Watanabe. (2016) The ubiquitin hybrid gene UBA52 regulates ubiquitination of ribosome and sustains embryonic development. Scientific Reports 6:1.
Crossref
Justin J. Yerbury, Lezanne Ooi, Andrew Dillin, Darren N. Saunders, Danny M. Hatters, Philip M. Beart, Neil R. Cashman, Mark R. Wilson & Heath Ecroyd. (2016) Walking the tightrope: proteostasis and neurodegenerative disease. Journal of Neurochemistry 137:4, pages 489-505.
Crossref
Qiang Fu, Yulin Huang, Zhiqiang Wang, Fumei Chen, Delun Huang, Yangqing Lu, Xianwei Liang & Ming Zhang. (2016) Proteome Profile and Quantitative Proteomic Analysis of Buffalo (Bubalusbubalis) Follicular Fluid during Follicle Development. International Journal of Molecular Sciences 17:5, pages 618.
Crossref
Bilge ÖZSAİT SELÇUK, Evrim KÖMÜRCÜ BAYRAK & Nihan ERGİNEL ÜNALTUNA. (2016) Higher expression level of Bat3 is associated with silencing of theMidn gene in primary mouse cardiomyocytes. TURKISH JOURNAL OF BIOLOGY 40, pages 1295-1302.
Crossref
Marzia Bianchi, Elisa Giacomini, Rita Crinelli, Lucia Radici, Elisa Carloni & Mauro Magnani. (2015) Dynamic transcription of ubiquitin genes under basal and stressful conditions and new insights into the multiple UBC transcript variants. Gene 573:1, pages 100-109.
Crossref
Jin-Yong Lee, Maki Tokumoto, Yasuyuki Fujiwara & Masahiko Satoh. (2015) Involvement of ubiquitin-coding genes in cadmium-induced protein ubiquitination in human proximal tubular cells. The Journal of Toxicological Sciences 40:6, pages 901-908.
Crossref
Liyun Yuan, Xiaoyan Tang, Binyan Zhang & Guohui Ding. (2015) Cell Pluripotency Levels Associated with Imprinted Genes in Human. Computational and Mathematical Methods in Medicine 2015, pages 1-8.
Crossref
Shewit Kalayou, Anne Grethe Hamre, Doreen Ndossi, Lisa Connolly, Morten Sørlie, Erik Ropstad & Steven Verhaegen. (2014) Using SILAC proteomics to investigate the effect of the mycotoxin, alternariol, in the human H295R steroidogenesis model. Cell Biology and Toxicology.
Crossref
Han-Wook Ryu, Chul-Woo Park & Kwon-Yul Ryu. (2014) Disruption of polyubiquitin gene Ubb causes dysregulation of neural stem cell differentiation with premature gliogenesis. Scientific Reports 4:1.
Crossref
Han-Wook Ryu, Chul-Woo Park & Kwon-Yul Ryu. (2014) Restoration of cellular ubiquitin reverses impairments in neuronal development caused by disruption of the polyubiquitin gene Ubb. Biochemical and Biophysical Research Communications 453:3, pages 443-448.
Crossref
Chul-Woo Park & Kwon-Yul Ryu. (2014) Cellular ubiquitin pool dynamics and homeostasis. BMB Reports 47:9, pages 475-482.
Crossref
Omar Mendoza-Porras, Natasha A. Botwright, Sean M. McWilliam, Mathew T. Cook, James O. Harris, Gene Wijffels & Michelle L. Colgrave. (2014) Exploiting genomic data to identify proteins involved in abalone reproduction. Journal of Proteomics 108, pages 337-353.
Crossref
Natsumi SHIMIZU, Kimihiro UENO, Ena KURITA, Seung-Wook SHIN, Takuji NISHIHARA, Tomoko AMANO, Masayuki ANZAI, Satoshi KISHIGAMI, Hiromi KATO, Tasuku MITANI, Yoshihiko HOSOI & Kazuya MATSUMOTO. (2014) Possible Role of ZPAC, Zygote-specific Proteasome Assembly Chaperone, During Spermatogenesis in the Mouse. Journal of Reproduction and Development 60:3, pages 179-186.
Crossref
Keiji Tanaka & Noriyuki Matsuda. (2014) Proteostasis and neurodegeneration: The roles of proteasomal degradation and autophagy. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1843:1, pages 197-204.
Crossref
Rohini Bose, Gurpreet Manku, Martine Culty & Simon S. Wing. 2014. Posttranslational Protein Modifications in the Reproductive System. Posttranslational Protein Modifications in the Reproductive System 181 213 .
Chenggang LuJongmin KimMargaret T. Fuller. (2013) The polyubiquitin gene Ubi-p63E is essential for male meiotic cell cycle progression and germ cell differentiation in Drosophila . Development 140:17, pages 3522-3531.
Crossref
Jada Hallengren, Ping-Chung Chen & Scott M. Wilson. (2013) Neuronal Ubiquitin Homeostasis. Cell Biochemistry and Biophysics 67:1, pages 67-73.
Crossref
Sandrine Puverel & Lino Tessarollo. 2013. Gametogenesis. Gametogenesis 357 384 .
Gurpreet Manku, Simon S. Wing & Martine Culty. (2012) Expression of the Ubiquitin Proteasome System in Neonatal Rat Gonocytes and Spermatogonia: Role in Gonocyte Differentiation1. Biology of Reproduction 87:2.
Crossref
Sayaka Koyanagi, Hiroko Hamasaki, Satoshi Sekiguchi, Kenshiro Hara, Yoshiyuki Ishii, Shigeru Kyuwa & Yasuhiro Yoshikawa. (2012) Effects of ubiquitin C-terminal hydrolase L1 deficiency on mouse ova. REPRODUCTION 143:3, pages 271-279.
Crossref
Kwon-Yul Ryu, Hyejin Park, Derrick J. Rossi, Irving L. Weissman & Ron R. Kopito. (2012) Perturbation of the Hematopoietic System during Embryonic Liver Development Due to Disruption of Polyubiquitin Gene Ubc in Mice. PLoS ONE 7:2, pages e32956.
Crossref
Chul-Woo Park, Han-Wook Ryu & Kwon-Yul Ryu. (2012) Locus coeruleus neurons are resistant to dysfunction and degeneration by maintaining free ubiquitin levels although total ubiquitin levels decrease upon disruption of polyubiquitin gene Ubb. Biochemical and Biophysical Research Communications 418:3, pages 541-546.
Crossref
Shamim A. Sinnar, Christopher L. Small, Ryan M. Evanoff, Laura G. Reinholdt, Michael D. Griswold, Ron R. Kopito & Kwon-Yul Ryu. (2011) Altered testicular gene expression patterns in mice lacking the polyubiquitin gene Ubb. Molecular Reproduction and Development 78:6, pages 415-425.
Crossref
B. Heindryckx, S. Lierman, C. M. Combelles, C. A. Cuvelier, J. Gerris & P. De Sutter. (2011) Aberrant spindle structures responsible for recurrent human metaphase I oocyte arrest with attempts to induce meiosis artificially. Human Reproduction 26:4, pages 791-800.
Crossref
Han-Wook Ryu & Kwon-Yul Ryu. (2011) Quantification of oxidative stress in live mouse embryonic fibroblasts by monitoring the responses of polyubiquitin genes. Biochemical and Biophysical Research Communications 404:1, pages 470-475.
Crossref
Stephanie Beall, Carol Brenner & James Segars. (2010) Oocyte maturation failure: a syndrome of bad eggs. Fertility and Sterility 94:7, pages 2507-2513.
Crossref
Brigit E. Riley, Stephen E. Kaiser, Thomas A. Shaler, Aylwin C.Y. Ng, Taichi Hara, Mark S. Hipp, Kasper Lage, Ramnik J. Xavier, Kwon-Yul Ryu, Keiko Taguchi, Masayuki Yamamoto, Keiji Tanaka, Noboru Mizushima, Masaaki Komatsu & Ron R. Kopito. (2010) Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection. Journal of Cell Biology 191:3, pages 537-552.
Crossref
K.-Y. Ryu, N. Fujiki, M. Kazantzis, J. C. Garza, D. M. Bouley, A. Stahl, X.-Y. Lu, S. Nishino & R. R. Kopito. (2009) Loss of polyubiquitin gene Ubb leads to metabolic and sleep abnormalities in mice. Neuropathology and Applied Neurobiology 36:4, pages 285-299.
Crossref
Y. Kimura & K. Tanaka. (2010) Regulatory mechanisms involved in the control of ubiquitin homeostasis. Journal of Biochemistry 147:6, pages 793-798.
Crossref
P Wu, Y Tian, G Chen, B Wang, L Gui, L Xi, X Ma, Y Fang, T Zhu, D Wang, L Meng, G Xu, S Wang, D Ma & J Zhou. (2009) Ubiquitin B: an essential mediator of trichostatin A-induced tumor-selective killing in human cancer cells. Cell Death & Differentiation 17:1, pages 109-118.
Crossref
Marzia Bianchi, Rita Crinelli, Elisa Giacomini, Elisa Carloni & Mauro Magnani. (2009) A potent enhancer element in the 5′-UTR intron is crucial for transcriptional regulation of the human ubiquitin C gene. Gene 448:1, pages 88-101.
Crossref
Alexei V. Evsikov & Caralina Marín de Evsikova. (2009) Gene expression during the oocyte-to-embryo transition in mammals. Molecular Reproduction and Development 76:9, pages 805-818.
Crossref
John S. Bett, Caroline L. Benn, Kwon‐Yul Ryu, Ron R. Kopito & Gillian P. Bates. (2008) The polyubiquitin Ubc gene modulates histone H2A monoubiquitylation in the R6/2 mouse model of Huntington's disease . Journal of Cellular and Molecular Medicine 13:8b, pages 2645-2657.
Crossref
Siddhartha Mitra, Andrey S. Tsvetkov & Steven Finkbeiner. (2009) Single Neuron Ubiquitin-Proteasome Dynamics Accompanying Inclusion Body Formation in Huntington Disease. Journal of Biological Chemistry 284:7, pages 4398-4403.
Crossref
D. Escalier. (2008) Les souris génétiquement modifiées au service de la reproduction. Gynécologie Obstétrique & Fertilité 36:12, pages 1224-1229.
Crossref
Kwon-Yul Ryu, Jacob C. Garza, Xin-Yun Lu, Gregory S. Barsh & Ron R. Kopito. (2008) Hypothalamic neurodegeneration and adult-onset obesity in mice lacking the Ubb polyubiquitin gene . Proceedings of the National Academy of Sciences 105:10, pages 4016-4021.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.