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Molecular and Cellular Biology Volume 30, 2010 - Issue 12
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Article

Glucose Controls Nuclear Accumulation, Promoter Binding, and Transcriptional Activity of the MondoA-Mlx Heterodimer

Christopher W. PetersonHuntsman Cancer Institute, Department of Oncological Sciences, University of Utah, Salt Lake City, Utah84112-5550
,
Carrie A. StoltzmanHuntsman Cancer Institute, Department of Oncological Sciences, University of Utah, Salt Lake City, Utah84112-5550
,
Michael P. SighinolfiHuntsman Cancer Institute, Department of Oncological Sciences, University of Utah, Salt Lake City, Utah84112-5550
,
Kyoung-Sim HanHuntsman Cancer Institute, Department of Oncological Sciences, University of Utah, Salt Lake City, Utah84112-5550
&
Donald E. AyerHuntsman Cancer Institute, Department of Oncological Sciences, University of Utah, Salt Lake City, Utah84112-5550Correspondence[email protected]
Pages 2887-2895 | Received 16 Dec 2009, Accepted 03 Apr 2010, Published online: 20 Mar 2023

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Zhizhou Ye & Donald E. Ayer. (2018) Ras Suppresses TXNIP Expression by Restricting Ribosome Translocation. Molecular and Cellular Biology 38:20.
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Mohan R. Kaadige, Jingye Yang, Blake R. Wilde & Donald E. Ayer. (2015) MondoA-Mlx Transcriptional Activity Is Limited by mTOR-MondoA Interaction. Molecular and Cellular Biology 35:1, pages 101-110.
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John L. Petrie, Ziad H. Al-Oanzi, Catherine Arden, Susan J. Tudhope, Jelena Mann, Julius Kieswich, Muhammad M. Yaqoob, Howard C. Towle & Loranne Agius. (2013) Glucose Induces Protein Targeting to Glycogen in Hepatocytes by Fructose 2,6-Bisphosphate-Mediated Recruitment of MondoA to the Promoter. Molecular and Cellular Biology 33:4, pages 725-738.
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Mohan R. Kaadige, Marc G. Elgort & Donald E. Ayer. (2010) Coordination of glucose and glutamine utilization by an expanded Myc network. Transcription 1:1, pages 36-40.
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Articles from other publishers (59)

Byungyong Ahn. (2023) The Function of MondoA and ChREBP Nutrient—Sensing Factors in Metabolic Disease. International Journal of Molecular Sciences 24:10, pages 8811.
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Tian-Yeh Lim, Blake R. Wilde, Mallory L. Thomas, Kristin E. Murphy, Jeffery M. Vahrenkamp, Megan E. Conway, Katherine E. Varley, Jason Gertz & Donald E. Ayer. (2023) TXNIP loss expands Myc-dependent transcriptional programs by increasing Myc genomic binding. PLOS Biology 21:3, pages e3001778.
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Yemin Zhu, Nannan Xu, Siming Wu, Yu Luan, Huiyi Ke, Lifang Wu, Yakui Li, Ying Lu, Xindan Xing, Na Tian, Qi Liu, Lingfeng Tong, Lei Hu, Yingning Ji, Zhangbing Chen, Ping Zhang & Xuemei Tong. (2022) MEK1 ‐dependent MondoA phosphorylation regulates glucose uptake in response to ketone bodies in colorectal cancer cells . Cancer Science 114:3, pages 961-975.
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Edward V. Prochownik. (2022) Regulation of Normal and Neoplastic Proliferation and Metabolism by the Extended Myc Network. Cells 11:24, pages 3974.
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Junbi Hu, Lin Feng, Mudan Ren, Yan Zhao, Guifang Lu, Xinlan Lu, Yarui Li, Xin Wang, Xin Bu, Shuai Wang, Liangliang Shen & Shuixiang He. (2021) Colorectal Cancer Cell Differentiation Is Dependent on the Repression of Aerobic Glycolysis by NDRG2-TXNIP Axis. Digestive Diseases and Sciences 67:8, pages 3763-3772.
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Jiachen Li, Jianmin Pan, Yang Liu, Xiaohui Luo, Cheng Yang, Wangfa Xiao, Qishang Li, Lihui Yang & Xiaodong Zhang. (2022) 3‑Bromopyruvic acid regulates glucose metabolism by targeting the c‑Myc/TXNIP axis and induces mitochondria‑mediated apoptosis in TNBC cells. Experimental and Therapeutic Medicine 24:2.
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Francine J. Boonekamp, Ewout Knibbe, Marcel A. Vieira-Lara, Melanie Wijsman, Marijke A.H. Luttik, Karen van Eunen, Maxime den Ridder, Reinier Bron, Ana Maria Almonacid Suarez, Patrick van Rijn, Justina C. Wolters, Martin Pabst, Jean-Marc Daran, Barbara M. Bakker & Pascale Daran-Lapujade. (2022) Full humanization of the glycolytic pathway in Saccharomyces cerevisiae. Cell Reports 39:13, pages 111010.
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Hitomi Yamamoto-Imoto, Satoshi Minami, Tatsuya Shioda, Yurina Yamashita, Shinsuke Sakai, Shihomi Maeda, Takeshi Yamamoto, Shinya Oki, Mizuki Takashima, Tadashi Yamamuro, Kyosuke Yanagawa, Ryuya Edahiro, Miki Iwatani, Mizue So, Ayaka Tokumura, Toyofumi Abe, Ryoichi Imamura, Norio Nonomura, Yukinori Okada, Donald E. Ayer, Hidesato Ogawa, Eiji Hara, Yoshitsugu Takabatake, Yoshitaka Isaka, Shuhei Nakamura & Tamotsu Yoshimori. (2022) Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis. Cell Reports 38:9, pages 110444.
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Alexandra SipolErik Hameister, Busheng Xue, Julia Hofstetter, Maxim BarenboimRupert Öllinger, Gaurav JainCarolin Prexler, Rebeca Alba RubioMichaela C. BaldaufDavide G. Franchina, Andreas PetryJuliane SchmähUwe ThielAgnes GörlachGunnar CarioDirk Brenner, Günther H. S. Richter, Thomas G. P. GrünewaldRoland RadElmar Wolf, Jürgen Ruland, Poul H. Sorensen & Stefan E. G. Burdach. (2022) MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress. Blood 139:8, pages 1184-1197.
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Edward V. Prochownik & Huabo Wang. (2022) Normal and Neoplastic Growth Suppression by the Extended Myc Network. Cells 11:4, pages 747.
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Katsumi Iizuka. (2021) The Roles of Carbohydrate Response Element Binding Protein in the Relationship between Carbohydrate Intake and Diseases. International Journal of Molecular Sciences 22:21, pages 12058.
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Cong Xiang, Yannan Zhang, Qiaoli Chen, Aina Sun, Yamei Peng, Guoxin Zhang, Danxia Zhou, Yinyin Xie, Xiaoshuang Hou, Fangfang Zheng, Fan Wang, Zhenji Gan, Shuai Chen & Geng Liu. (2021) Increased glycolysis in skeletal muscle coordinates with adipose tissue in systemic metabolic homeostasis. Journal of Cellular and Molecular Medicine 25:16, pages 7840-7854.
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Huiyi Ke, Yu Luan, Siming Wu, Yemin Zhu & Xuemei Tong. (2021) The Role of Mondo Family Transcription Factors in Nutrient-Sensing and Obesity. Frontiers in Endocrinology 12.
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Blake R. Wilde, Mohan R. Kaadige, Katrin P. Guillen, Andrew Butterfield, Bryan E. Welm & Donald E. Ayer. (2020) Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate. Cancer & Metabolism 8:1.
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Aarthi Subramani, Prianca Griggs, Niah Frantzen, James Mendez, Jamila Tucker, Jada Murriel, Linda M. Sircy, Grace E. Millican, Erin E. McClelland, Rebecca L. Seipelt-Thiemann & David E. Nelson. (2020) Intracellular Cryptococcus neoformans disrupts the transcriptome profile of M1- and M2-polarized host macrophages. PLOS ONE 15:8, pages e0233818.
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Xueyun Zhang, Tao Fu, Qian He, Xiang Gao & Yan Luo. (2020) Glucose-6-Phosphate Upregulates Txnip Expression by Interacting With MondoA. Frontiers in Molecular Biosciences 6.
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Byungyong Ahn, Shibiao Wan, Natasha Jaiswal, Rick B. Vega, Donald E. Ayer, Paul M. Titchenell, Xianlin Han, Kyoung Jae Won & Daniel P. Kelly. (2019) MondoA drives muscle lipid accumulation and insulin resistance. JCI Insight 4:15.
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