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Article

Zinc Finger Protein Zbtb20 Is Essential for Postnatal Survival and Glucose Homeostasis

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Pages 2804-2815 | Received 27 Oct 2008, Accepted 21 Feb 2009, Published online: 21 Mar 2023

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B. Hervé, D. Fauvert, R. Dard, J. Roume, S. Cognard, D. Goidin, F. Lozach, D. Molina-Gomes & F. Vialard. (2016) The emerging microduplication 3q13.31: Expanding the genotype-phenotype correlations of the reciprocal microdeletion 3q13.31 syndrome. European Journal of Medical Genetics 59:9, pages 463-469.
Crossref
Sonia Alonso-Martin, Anne Rochat, Despoina Mademtzoglou, Jessica Morais, Aurélien de Reyniès, Frédéric Auradé, Ted Hung-Tse Chang, Peter S. Zammit & Frédéric Relaix. (2016) Gene Expression Profiling of Muscle Stem Cells Identifies Novel Regulators of Postnatal Myogenesis. Frontiers in Cell and Developmental Biology 4.
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Yuanyuan Chen, Shengsheng Yang, Jiewei Hu, Chaoqin Yu, Miaoxia He & Zailong Cai. (2016) Increased Expression of SETD7 Promotes Cell Proliferation by Regulating Cell Cycle and Indicates Poor Prognosis in Hepatocellular Carcinoma. PLOS ONE 11:5, pages e0154939.
Crossref
Dongmei Cao, Xianhua Ma, Jiao Cai, Jing Luan, An-Jun Liu, Rui Yang, Yi Cao, Xiaotong Zhu, Hai Zhang, Yu-Xia Chen, Yuguang Shi, Guang-Xia Shi, Dajin Zou, Xuetao Cao, Michael J. Grusby, Zhifang Xie & Weiping J. Zhang. (2016) ZBTB20 is required for anterior pituitary development and lactotrope specification. Nature Communications 7:1.
Crossref
Heping Kan, Yuqi Huang, Xianghong Li, Dingli Liu, Jianjia Chen & Miaojiang Shu. (2016) Zinc finger protein ZBTB20 is an independent prognostic marker and promotes tumor growth of human hepatocellular carcinoma by repressing FoxO1. Oncotarget 7:12, pages 14336-14349.
Crossref
Xinlu Yuan, Jie Wang, Xiaoyan Tang, Yixue Li, Pu Xia & Xin Gao. (2015) Berberine ameliorates nonalcoholic fatty liver disease by a global modulation of hepatic mRNA and lncRNA expression profiles. Journal of Translational Medicine 13:1.
Crossref
Ines Quintela, Lorena Gomez-Guerrero, Montse Fernandez-Prieto, Mariela Resches, Francisco Barros & Angel Carracedo. (2015) Female patient with autistic disorder, intellectual disability, and co-morbid anxiety disorder: Expanding the phenotype associated with the recurrent 3q13.2-q13.31 microdeletion. American Journal of Medical Genetics Part A 167:12, pages 3121-3129.
Crossref
Hai Zhang, Dongmei Cao, Luting Zhou, Ye Zhang, Xiaoqin Guo, Hui Li, Yuxia Chen, Brett T. Spear, Jia-Wei Wu, Zhifang Xie & Weiping J. Zhang. (2015) ZBTB20 is a sequence-specific transcriptional repressor of alpha-fetoprotein gene. Scientific Reports 5:1.
Crossref
Guangdi Zhou, Xuchao Jiang, Hai Zhang, Yinzhong Lu, Anjun Liu, Xianhua Ma, Guan Yang, Rui Yang, Hongxing Shen, Jianming Zheng, Yiping Hu, Xiao Yang, Weiping J. Zhang & Zhifang Xie. (2015) Zbtb20 regulates the terminal differentiation of hypertrophic chondrocytes via repression of Sox9 . Development 142:2, pages 385-393.
Crossref
Jun-gang Zhao, Kai-ming Ren & Jun Tang. (2014) Zinc finger protein ZBTB20 promotes cell proliferation in non-small cell lung cancer through repression of FoxO1. FEBS Letters 588:24, pages 4536-4542.
Crossref
Xiaohua Jiang, Huan Zhang, Shi Yin, Yuanwei Zhang, Weimei Yang, Wei Zheng, Liu Wang, Zheng Wang, Ihtisham Bukhari, Howard J. Cooke, Furhan Iqbal & Qinghua Shi. (2014) Specific deficiency of Plzf paralog, Zbtb20, in Sertoli cells does not affect spermatogenesis and fertility in mice. Scientific Reports 4:1.
Crossref
Viviana Cordeddu, Bert Redeker, Emilia Stellacci, Aldo Jongejan, Alessandra Fragale, Ted E J Bradley, Massimiliano Anselmi, Andrea Ciolfi, Serena Cecchetti, Valentina Muto, Laura Bernardini, Meron Azage, Daniel R Carvalho, Alberto J Espay, Alison Male, Anna-Maja Molin, Renata Posmyk, Carla Battisti, Alberto Casertano, Daniela Melis, Antoine van Kampen, Frank Baas, Marcel M Mannens, Gianfranco Bocchinfuso, Lorenzo Stella, Marco Tartaglia & Raoul C Hennekam. (2014) Mutations in ZBTB20 cause Primrose syndrome. Nature Genetics 46:8, pages 815-817.
Crossref
Stéphane Chevrier, Dianne Emslie, Wei Shi, Tobias Kratina, Cameron Wellard, Alexander Karnowski, Erdem Erikci, Gordon K. Smyth, Kamal Chowdhury, David Tarlinton & Lynn M. Corcoran. (2014) The BTB-ZF transcription factor Zbtb20 is driven by Irf4 to promote plasma cell differentiation and longevity. Journal of Experimental Medicine 211:5, pages 827-840.
Crossref
Yinan Wang & Deepta Bhattacharya. (2014) Adjuvant-specific regulation of long-term antibody responses by ZBTB20. Journal of Experimental Medicine 211:5, pages 841-856.
Crossref
MOMOKO YOSHIDA, YUKO WATANABE, KYOSUKE YAMANISHI, AKIFUMI YAMASHITA, HIDEYUKI YAMAMOTO, DAISUKE OKUZAKI, KAZUNORI SHIMADA, HIROSHI NOJIMA, TERUO YASUNAGA, HARUKI OKAMURA, HISATO MATSUNAGA & HIROMICHI YAMANISHI. (2014) Analysis of genes causing hypertension and stroke in spontaneously hypertensive rats: Gene expression profiles in the brain. International Journal of Molecular Medicine 33:4, pages 887-896.
Crossref
Emmanouil Karavitakis, Sofia Kitsiou-Tzeli, Athena Xaidara, Konstantina Kosma, Periklis Makrythanasis, Eleni Apazidou, Emmanuel Kanavakis & Maria Tzetis. (2014) Microduplication 3q13.2q13.31 identified in a male with dysmorphic features and multiple congenital anomalies. American Journal of Medical Genetics Part A 164:3, pages 666-670.
Crossref
Emilie A Bard-Chapeau, Anh-Tuan Nguyen, Alistair G Rust, Ahmed Sayadi, Philip Lee, Belinda Q Chua, Lee-Sun New, Johann de Jong, Jerrold M Ward, Christopher K Y Chin, Valerie Chew, Han Chong Toh, Jean-Pierre Abastado, Touati Benoukraf, Richie Soong, Frederic A Bard, Adam J Dupuy, Randy L Johnson, George K Radda, Eric Chun Yong Chan, Lodewyk F A Wessels, David J Adams, Nancy A Jenkins & Neal G Copeland. (2013) Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model. Nature Genetics 46:1, pages 24-32.
Crossref
Marie-Laure Vuillaume, Marie-Ange Delrue, Sophie Naudion, Jérôme Toutain, Patricia Fergelot, Benoit Arveiler, Didier Lacombe & Caroline Rooryck. (2013) Expanding the clinical phenotype at the 3q13.31 locus with a new case of microdeletion and first characterization of the reciprocal duplication. Molecular Genetics and Metabolism 110:1-2, pages 90-97.
Crossref
Xingguang Liu, Peng Zhang, Yan Bao, Yanmei Han, Yan WangQian Zhang, Zhenzhen Zhan, Jun Meng, Yingke Li, Nan Li, Weiping J. ZhangXuetao Cao. (2013) Zinc finger protein ZBTB20 promotes toll-like receptor-triggered innate immune responses by repressing IκBα gene transcription . Proceedings of the National Academy of Sciences 110:27, pages 11097-11102.
Crossref
Eva H. Rosenthal, Anton B. Tonchev, Anastassia Stoykova & Kamal Chowdhury. (2012) Regulation of archicortical arealization by the transcription factor Zbtb20. Hippocampus 22:11, pages 2144-2156.
Crossref
Anjing Ren, Huan Zhang, Zhifang Xie, Xianhua Ma, Wenli Ji, David Z.Z. He, Wenjun Yuan, Yu-Qiang Ding, Xiao-Hui Zhang & Weiping J. Zhang. (2012) Regulation of hippocampus-dependent memory by the zinc finger protein Zbtb20 in mature CA1 neurons. The Journal of Physiology 590:19, pages 4917-4932.
Crossref
Ye Zhang, Zhifang Xie, Luting Zhou, Ling Li, Hai Zhang, Guangdi Zhou, Xianhua Ma, Pedro L. Herrera, Zhimin Liu, Michael J. Grusby & Weiping J. Zhang. (2012) The Zinc Finger Protein ZBTB20 Regulates Transcription of Fructose-1,6-Bisphosphatase 1 and β Cell Function in Mice. Gastroenterology 142:7, pages 1571-1580.e6.
Crossref
Yan WANG, Ke-jia WANG, Ling LI, Rong CHEN, Xian-hua MA, Xiao-qin GUO, Ye ZHANG, Da-jin ZOU, Zhi-fang XIE & Wei-ping ZHANG. (2012) Preparation and application of monoclonal antibodies against novel zinc finger protein ZBTB45. Academic Journal of Second Military Medical University 31:12, pages 1277-1281.
Crossref
Qing Wang, Ye-xiong Tan, Yi-bin Ren, Li-wei Dong, Zhi-fang Xie, Liang Tang, Dan Cao, Wei-ping Zhang, He-ping Hu & Hong-yang Wang. (2011) Zinc finger protein ZBTB20 expression is increased in hepatocellular carcinoma and associated with poor prognosis. BMC Cancer 11:1.
Crossref
Martha L. Peterson, Chunhong Ma & Brett T. Spear. (2011) Zhx2 and Zbtb20: Novel regulators of postnatal alpha-fetoprotein repression and their potential role in gene reactivation during liver cancer. Seminars in Cancer Biology 21:1, pages 21-27.
Crossref
Joseph Locker. 2011. Molecular Pathology of Liver Diseases. Molecular Pathology of Liver Diseases 193 211 .
Hai ZHANG, Zhi-fang XIE, Szpirer Claude & Wei-ping ZHANG. (2010) Pathological implication of postnatally up-regulated AFP expression in ZBTB20 knockout neonatal mice. Academic Journal of Second Military Medical University 30:10, pages 1045-1048.
Crossref
Hai ZHANG, Zhi-fang XIE, Szpirer Claude & Wei-ping ZHANG. (2010) Pathological implication of postnatally up-regulated AFP expression in ZBTB20 knockout neonatal mice. Academic Journal of Second Military Medical University 30:10, pages 1045-1048.
Crossref
Ye Zhang, Zhifang Xie, Guangdi Zhou, Hai Zhang, Jian Lu & Weiping J. Zhang. (2010) Fructose-1,6-Bisphosphatase Regulates Glucose-Stimulated Insulin Secretion of Mouse Pancreatic β-Cells. Endocrinology 151:10, pages 4688-4695.
Crossref
Zhifang Xie, Xianhua MaWenli JiGuangdi ZhouYinzhong LuZhenghua Xiang, Yan X. WangLei Zhang, Yiping Hu, Yu-Qiang Ding & Weiping J. Zhang. (2010) Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus. Proceedings of the National Academy of Sciences 107:14, pages 6510-6515.
Crossref

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