45
Views
33
CrossRef citations to date
0
Altmetric
Article

Up-Regulation of P-TEFb by the MEK1-Extracellular Signal-Regulated Kinase Signaling Pathway Contributes to Stimulated Transcription Elongation of Immediate Early Genes in Neuroendocrine Cells

, , &
Pages 1630-1643 | Received 26 Sep 2007, Accepted 07 Dec 2007, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Cristian Moiola, Paola De Luca, Kevin Gardner, Elba Vazquez & Adriana De Siervi. (2010) Cyclin T1 overexpression induces malignant transformation and tumor growth. Cell Cycle 9:15, pages 3191-3198.
Read now
Toshitsugu Fujita & Werner Schlegel. (2010) Promoter-proximal pausing of RNA polymerase II: an opportunity to regulate gene transcription. Journal of Receptors and Signal Transduction 30:1, pages 31-42.
Read now

Articles from other publishers (31)

Steven Sher, Ethan Whipp, Janek Walker, Pu Zhang, Larry Beaver, Katie Williams, Shelley Orwick, Janani Ravikrishnan, Brandi Walker, Elizabeth Perry, Charles Gregory, Matthew Purcell, Alexander Pan, Pearlly Yan, Lapo Alinari, Amy J. Johnson, Melanie M. Frigault, Joy M. Greer, Ahmed Hamdy, Raquel Izumi, Xiaokui Mo, Deepa Sampath, Jennifer Woyach, James Blachly, John C. Byrd & Rosa Lapalombella. (2022) VIP152 is a selective CDK9 inhibitor with pre-clinical in vitro and in vivo efficacy in chronic lymphocytic leukemia. Leukemia 37:2, pages 326-338.
Crossref
Chunlei Ji, Yue Yang, Yujuan Fu, Xinyi Pu & Guangyu Xu. (2022) Improvement of Ganoderma lucidum water extract on the learning and memory impairment and its mechanism in d-galactose-induced aging mice. Journal of Functional Foods 99, pages 105322.
Crossref
Stefano Spada, Brian Luke & Sven Danckwardt. (2022) The Bidirectional Link Between RNA Cleavage and Polyadenylation and Genome Stability: Recent Insights From a Systematic Screen. Frontiers in Genetics 13.
Crossref
Lick Pui Lai, Viviane Brel, Kanika Sharma, Julia Frappier, Nadia Le-Henanf, Bertrand Vivet, Nicolas Muzet, Emilie Schell, Renaud Morales, Eamonn Rooney, Nicolas Basse, Ming Yi, Frederic Lacroix, Matthew Holderfield, Walter Englaro, Christophe Marcireau, Laurent Debussche, Dwight V. Nissley & Frank McCormick. (2021) Sensitivity of Oncogenic KRAS-Expressing Cells to CDK9 Inhibition. SLAS Discovery 26:7, pages 922-932.
Crossref
Stephen Small & David N Arnosti. (2020) Transcriptional Enhancers in Drosophila . Genetics 216:1, pages 1-26.
Crossref
Subham Basu, Arijit Nandy & Debabrata Biswas. (2020) Keeping RNA polymerase II on the run: Functions of MLL fusion partners in transcriptional regulation. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1863:8, pages 194563.
Crossref
Megan J. Bywater, Deborah L. Burkhart, Jasmin Straube, Arianna Sabò, Vera Pendino, James E. Hudson, Gregory A. Quaife-Ryan, Enzo R. Porrello, James Rae, Robert G. Parton, Theresia R. Kress, Bruno Amati, Trevor D. Littlewood, Gerard I. Evan & Catherine H. Wilson. (2020) Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity. Nature Communications 11:1.
Crossref
Koh Fujinaga. (2020) P-TEFb as A Promising Therapeutic Target. Molecules 25:4, pages 838.
Crossref
Muhammed H. Rahaman, Frankie Lam, Longjin Zhong, Theodosia Teo, Julian Adams, Mingfeng Yu, Robert W. Milne, Chris Pepper, Noor A. Lokman, Carmela Ricciardelli, Martin K. Oehler & Shudong Wang. (2019) Targeting CDK9 for treatment of colorectal cancer. Molecular Oncology 13:10, pages 2178-2193.
Crossref
Monika Nováková, Marek Hampl, Dávid Vrábel, Jan Procházka, Silvia Petrezselyová, Michaela Procházková, Radislav Sedláček, Michaela Kavková, Tomáš Zikmund, Jozef Kaiser, Hsien-Chia Juan, Ming-Ji Fann, Marcela Buchtová & Jiří Kohoutek. (2019) Mouse Model of Congenital Heart Defects, Dysmorphic Facial Features and Intellectual Developmental Disorders as a Result of Non-functional CDK13. Frontiers in Cell and Developmental Biology 7.
Crossref
Mariona Nadal-Ribelles, Carme Solé, Gerard Martínez-Cebrián, Francesc Posas & Eulàlia de Nadal. 2019. Gene Expression and Control. Gene Expression and Control.
William K. Songock, Matthew L. Scott & Jason M. Bodily. (2017) Regulation of the human papillomavirus type 16 late promoter by transcriptional elongation. Virology 507, pages 179-191.
Crossref
M. Mikula, M. Skrzypczak, K. Goryca, K. Paczkowska, J.K. Ledwon, M. Statkiewicz, M. Kulecka, M. Grzelak, M. Dabrowska, U. Kuklinska, J. Karczmarski, I. Rumienczyk, K. Jastrzebski, M. Miaczynska, K. Ginalski, K. Bomsztyk & J. Ostrowski. (2016) Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy. Nucleic Acids Research, pages gkw763.
Crossref
Daniel P. Morris, Beilei Lei, Lawrence D. Longo, Karol Bomsztyk, Debra A. Schwinn & Gregory A. Michelotti. (2015) Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation. PLOS ONE 10:8, pages e0134442.
Crossref
Mellissa J. Hicks, Qiuping Hu, Erin Macrae & James DeWille. (2015) Mitogen-activated protein kinase signaling controls basal and oncostatin M-mediated JUNB gene expression. Molecular and Cellular Biochemistry 403:1-2, pages 115-124.
Crossref
Toshitsugu Fujita, Fusako Kitaura & Hodaka Fujii. (2015) A Critical Role of the Thy28-MYH9 Axis in B Cell-Specific Expression of the Pax5 Gene in Chicken B Cells. PLOS ONE 10:1, pages e0116579.
Crossref
Jun An, Tongjian Cai, Honglei Che, Tao Yu, Zipeng Cao, Xinqin Liu, Fang Zhao, Jinfei Jing, Xuefeng Shen, Mingchao Liu, Kejun Du, Jingyuan Chen & Wenjing Luo. (2014) The changes of miRNA expression in rat hippocampus following chronic lead exposure. Toxicology Letters 229:1, pages 158-166.
Crossref
Valentin Le Douce, Thomas Cherrier, Raphael Riclet, Olivier Rohr & Christian Schwartz. (2014) The Many Lives of CTIP2: From AIDS to Cancer and Cardiac Hypertrophy. Journal of Cellular Physiology 229:5, pages 533-537.
Crossref
Tamara Salem, Tiphanie Gomard, Franck Court, Gabriel Moquet-Torcy, Frédérique Brockly, Thierry Forné & Marc Piechaczyk. (2013) Chromatin loop organization of the junb locus in mouse dendritic cells. Nucleic Acids Research 41:19, pages 8908-8925.
Crossref
Weimin Li, Rakesh S. Laishram & Richard A. Anderson. (2013) The novel poly(A) polymerase Star-PAP is a signal-regulated switch at the 3′-end of mRNAs. Advances in Biological Regulation 53:1, pages 64-76.
Crossref
Hendrik Marks, Tüzer Kalkan, Roberta Menafra, Sergey Denissov, Kenneth Jones, Helmut Hofemeister, Jennifer Nichols, Andrea Kranz, A. Francis Stewart, Austin Smith & Hendrik G. Stunnenberg. (2012) The Transcriptional and Epigenomic Foundations of Ground State Pluripotency. Cell 149:3, pages 590-604.
Crossref
Richard D. Palermo, Helen M. Webb & Michelle J. West. (2011) RNA Polymerase II Stalling Promotes Nucleosome Occlusion and pTEFb Recruitment to Drive Immortalization by Epstein-Barr Virus. PLoS Pathogens 7:10, pages e1002334.
Crossref
Jianlong Sun, Haihui Pan, Chengwei Lei, Bin Yuan, Sreejith J. Nair, Craig April, Balaji Parameswaran, Brandy Klotzle, Jian-Bing Fan, Jianhua Ruan & Rong Li. (2011) Genetic and Genomic Analyses of RNA Polymerase II-pausing Factor in Regulation of Mammalian Transcription and Cell Growth. Journal of Biological Chemistry 286:42, pages 36248-36257.
Crossref
Young Kyeung Kim, Uri Mbonye, Joseph Hokello & Jonathan Karn. (2011) T-Cell Receptor Signaling Enhances Transcriptional Elongation from Latent HIV Proviruses by Activating P-TEFb through an ERK-Dependent Pathway. Journal of Molecular Biology 410:5, pages 896-916.
Crossref
M. A. Q. Siddiqui, Michael Wagner, Jorge Espinoza-Derout, Facan Huang, Daniel Beckles & Eduardo Mascareno. 2011. Genes and Cardiovascular Function. Genes and Cardiovascular Function 199 211 .
Murat A. Cevher & Frida E. Kleiman. (2010) Connections between 3′‐end processing and DNA damage response. Wiley Interdisciplinary Reviews: RNA 1:1, pages 193-199.
Crossref
Robert J. White & Andrew D. Sharrocks. (2010) Coordinated control of the gene expression machinery. Trends in Genetics 26:5, pages 214-220.
Crossref
Toshitsugu Fujita, Isabelle Piuz & Werner Schlegel. (2009) The transcription elongation factors NELF, DSIF and P-TEFb control constitutive transcription in a gene-specific manner. FEBS Letters 583:17, pages 2893-2898.
Crossref
Ysadora Maisonnasse - Charital, Goedele van Haasteren, Abbas Massiha, Werner Schlegel & Toshitsugu Fujita. (2009) A functional NF-κB enhancer element in the first intron contributes to the control of c-fos transcription. Gene 430:1-2, pages 116-122.
Crossref
Toshitsugu Fujita, Isabelle Piuz & Werner Schlegel. (2009) Negative elongation factor NELF controls transcription of immediate early genes in a stimulus-specific manner. Experimental Cell Research 315:2, pages 274-284.
Crossref
Kamaleldin E. Elagib, Ivailo S. Mihaylov, Lorrie L. Delehanty, Grant C. Bullock, Kevin D. Ouma, Jill F. Caronia, Sara L. Gonias & Adam N. Goldfarb. (2008) Cross-talk of GATA-1 and P-TEFb in megakaryocyte differentiation. Blood 112:13, pages 4884-4894.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.