47
Views
111
CrossRef citations to date
0
Altmetric
Article

FKBP51 Promotes Assembly of the Hsp90 Chaperone Complex and Regulates Androgen Receptor Signaling in Prostate Cancer Cells

, , , , &
Pages 1243-1253 | Received 12 Dec 2008, Accepted 23 Dec 2009, Published online: 20 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Sagar Barge, Dhananjay Jade, Selvaraj Ayyamperumal, Prasenjit Manna, Jagat Borah, Chandrasekar Moola Joghee Nanjan, Moola Joghee Nanjan & Narayan Chandra Talukdar. (2022) Potential inhibitors for FKBP51: an in silico study using virtual screening, molecular docking and molecular dynamics simulation. Journal of Biomolecular Structure and Dynamics 40:24, pages 13799-13811.
Read now
Siwanon Jirawatnotai, Samanta Sharma, Wojciech Michowski, Bhoom Suktitipat, Yan Geng, John Quackenbush, Joshua E Elias, Steven P Gygi, Yaoyu E Wang & Piotr Sicinski. (2014) The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis. Cell Cycle 13:18, pages 2889-2900.
Read now
Hongbo Wang, Ming Jiang, Hongmei Cui, Mengqian Chen, Ralph Buttyan, Simon W. Hayward, Tsonwin Hai, Zhengxin Wang & Chunhong Yan. (2012) The Stress Response Mediator ATF3 Represses Androgen Signaling by Binding the Androgen Receptor. Molecular and Cellular Biology 32:16, pages 3190-3202.
Read now

Articles from other publishers (108)

Olga B. Soto, Christian S. Ramirez, Rina Koyani, Isela A. Rodriguez‐Palomares, Jessica R. Dirmeyer, Brian Grajeda, Sourav Roy & Marc B. Cox. (2023) Structure and function of the TPR‐domain immunophilins FKBP51 and FKBP52 in normal physiology and disease. Journal of Cellular Biochemistry.
Crossref
Steven Tisseverasinghe, Boris Bahoric, Maurice Anidjar, Stephan Probst & Tamim Niazi. (2023) Advances in PARP Inhibitors for Prostate Cancer. Cancers 15:6, pages 1849.
Crossref
Asat Baischew, Sarah Engel, Thomas M. Geiger, Martha C. Taubert & Felix Hausch. (2023) Structural and biochemical insights into FKBP51 as a Hsp90 co‐chaperone. Journal of Cellular Biochemistry.
Crossref
Nina R. Ortiz, Naihsuan Guy, Yenni A. Garcia, Jeffrey C. Sivils, Mario D. Galigniana & Marc B. Cox. 2023. The Networking of Chaperones by Co-Chaperones. The Networking of Chaperones by Co-Chaperones 41 80 .
Javier Pozas, Sara Álvarez Rodríguez, Víctor Albarrán Fernández, Javier Burgos, Matteo Santoni, Ray Manneh Kopp, Javier Molina-Cerrillo & Teresa Alonso-Gordoa. (2022) Androgen Receptor Signaling Inhibition in Advanced Castration Resistance Prostate Cancer: What Is Expected for the Near Future?. Cancers 14:24, pages 6071.
Crossref
Haozhe Zhang, Yi Zhou, Zengzhen Xing, Rajiv Kumar Sah, Junqi Hu & Hailiang Hu. (2022) Androgen Metabolism and Response in Prostate Cancer Anti-Androgen Therapy Resistance. International Journal of Molecular Sciences 23:21, pages 13521.
Crossref
Jian Zhang, Houde Li, Yu Liu, Kejia Zhao, Shiyou Wei, Eric T. Sugarman, Lunxu Liu & Gao Zhang. (2022) Targeting HSP90 as a Novel Therapy for Cancer: Mechanistic Insights and Translational Relevance. Cells 11:18, pages 2778.
Crossref
Gennady M. Verkhivker. (2022) Conformational Dynamics and Mechanisms of Client Protein Integration into the Hsp90 Chaperone Controlled by Allosteric Interactions of Regulatory Switches: Perturbation-Based Network Approach for Mutational Profiling of the Hsp90 Binding and Allostery. The Journal of Physical Chemistry B 126:29, pages 5421-5442.
Crossref
Xianquan An, Wanxu Guo, Huiying Wu, Xiying Fu, Ming Li, Yizhi Zhang, Yanlin Li, Ranji Cui, Wei Yang, Zhuo Zhang & Guoqing Zhao. (2022) Sex Differences in Depression Caused by Early Life Stress and Related Mechanisms. Frontiers in Neuroscience 16.
Crossref
Makoto Habara, Yuki Sato, Takahiro Goshima, Masashi Sakurai, Hiroyuki Imai, Hideyuki Shimizu, Yuta Katayama, Shunsuke Hanaki, Takahiro Masaki, Masahiro Morimoto, Sayaka Nishikawa, Tatsuya Toyama & Midori Shimada. (2022) FKBP52 and FKBP51 differentially regulate the stability of estrogen receptor in breast cancer. Proceedings of the National Academy of Sciences 119:15.
Crossref
Keisuke Maeda, Makoto Habara, Mitsuyasu Kawaguchi, Hiroaki Matsumoto, Shunsuke Hanaki, Takahiro Masaki, Yuki Sato, Hideyasu Matsuyama, Kazuki Kunieda, Hidehiko Nakagawa & Midori Shimada. (2021) FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells. Molecular Oncology 16:4, pages 940-956.
Crossref
Deborah Rotoli, Lucio Díaz-Flores, Ricardo Gutiérrez, Manuel Morales, Julio Ávila & Pablo Martín-Vasallo. (2021) AmotL2, IQGAP1, and FKBP51 Scaffold Proteins in Glioblastoma Stem Cell Niches. Journal of Histochemistry & Cytochemistry 70:1, pages 9-16.
Crossref
Richard S. Lee. 2022. Epigenetics of Stress and Stress Disorders. Epigenetics of Stress and Stress Disorders 1 18 .
Huadi Shi, Fulan Zhong, Xiaoqiong Yi, Zhenyi Shi, Feiyan Ou, Yufang Zuo & Zumin Xu. (2021) The Construction of a Prognostic Model Based on a Peptidyl Prolyl Cis–Trans Isomerase Gene Signature in Hepatocellular Carcinoma. Frontiers in Genetics 12.
Crossref
Yohko Yamazaki, Hikaru Abe, Chiharu Sakashita, Shun-Ichi Ohba, Takumi Watanabe, Isao Momose & Manabu Kawada. (2021) Androprostamine A: a unique antiprostate cancer agent. The Journal of Antibiotics 74:10, pages 717-725.
Crossref
Kanghyun Lee, Aye C. Thwin, Cory M. Nadel, Eric Tse, Stephanie N. Gates, Jason E. Gestwicki & Daniel R. Southworth. (2021) The structure of an Hsp90-immunophilin complex reveals cochaperone recognition of the client maturation state. Molecular Cell 81:17, pages 3496-3508.e5.
Crossref
Zoe R Maylin, Radu CB Nicolescu, Hardev Pandha & Mohammad Asim. (2021) Breaking androgen receptor addiction of prostate cancer by targeting different functional domains in the treatment of advanced disease. Translational Oncology 14:8, pages 101115.
Crossref
Maria V. Luna‐Velez, Jelmer J. Dijkstra, Marina A. Heuschkel, Frank P. Smit, Guillaume van de Zande, Dominique Smeets, J. P. Michiel Sedelaar, Michiel Vermeulen, Gerald W. Verhaegh & Jack A. Schalken. (2021) Androgen receptor signalling confers clonogenic and migratory advantages in urothelial cell carcinoma of the bladder. Molecular Oncology 15:7, pages 1882-1900.
Crossref
Zhenya Gao, Fang Yu, Huanxia Jia, Zhuo Ye & Shijie Yao. (2021) FK506-binding protein 5 promotes the progression of papillary thyroid carcinoma. Journal of International Medical Research 49:4, pages 030006052110083.
Crossref
Jian-Ting Han, Yongchang Zhu, Da-Bo Pan, Hong-Xiang Xue, Shuang Wang, Yali Peng, Huanxiang Liu, Yong-Xing He & Xiaojun Yao. (2021) Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography. Computational and Structural Biotechnology Journal 19, pages 4079-4091.
Crossref
Jing Zhang, Dan Wu, Yongxing He, Lanlan Li, Shanhui Liu, Jianzhong Lu, Huiming Gui, Yuhan Wang, Yan Tao, Hanzhang Wang, Dharam Kaushik, Ronald Rodriguez & Zhiping Wang. (2020) Rapamycin inhibits AR signaling pathway in prostate cancer by interacting with the FK1 domain of FKBP51. Biochemistry and Biophysics Reports 23, pages 100778.
Crossref
Yen-Wei Chu, Ching-Hsuan Chien, Mei-I Sung, Chi-Wei Chen & Yu-Ting Chen. (2020) dBMHCC: A comprehensive hepatocellular carcinoma (HCC) biomarker database provides a reliable prediction system for novel HCC phosphorylated biomarkers. PLOS ONE 15:6, pages e0234084.
Crossref
Priyatham Gorjala, Rick A. Kittles, Oscar B. Goodman Jr.Ranjana Mitra. (2020) Role of CYP3A5 in Modulating Androgen Receptor Signaling and Its Relevance to African American Men with Prostate Cancer. Cancers 12:4, pages 989.
Crossref
Sonia A. De Leo, Nadia R. Zgajnar, Gisela I. Mazaira, Alejandra G. Erlejman & Mario D. Galigniana. (2020) Role of the Hsp90-Immunophilin Heterocomplex in Cancer Biology. Current Cancer Therapy Reviews 16:1, pages 19-28.
Crossref
Yu Chen, Zhiqiang Liu, Yuequn Wang, Jian Zhuang, Yun Peng, Xiaoyang Mo, Jimei Chen, Yan Shi, Mengxiong Yu, Wanwan Cai, Yahuan Li, Xiaolan Zhu, Wuzhou Yuan, Yongqing Li, Fang Li, Zuoqiong Zhou, Guo Dai, Xiangli Ye, Yongqi Wan, Zhigang Jiang, Ping Zhu, Xiongwei Fan & Xiushan Wu. (2020) FKBP51 induces p53‑dependent apoptosis and enhances drug sensitivity of human non‑small‑cell lung cancer cells. Experimental and Therapeutic Medicine.
Crossref
Cristina Daneri-Becerra, Nadia R. Zgajnar, Cecilia M. Lotufo, Ana B. Ramos Hryb, Graciela Piwien-Pilipuk & Mario D. Galigniana. (2019) Regulation of FKBP51 and FKBP52 functions by post-translational modifications. Biochemical Society Transactions 47:6, pages 1815-1831.
Crossref
Nadia Zgajnar, Sonia De Leo, Cecilia Lotufo, Alejandra Erlejman, Graciela Piwien-Pilipuk & Mario Galigniana. (2019) Biological Actions of the Hsp90-binding Immunophilins FKBP51 and FKBP52. Biomolecules 9:2, pages 52.
Crossref
Andreas Hähle, Stephanie Merz, Christian Meyners & Felix Hausch. (2019) The Many Faces of FKBP51. Biomolecules 9:1, pages 35.
Crossref
Mario D. Galigniana. 2019. Heat Shock Protein 90 in Human Diseases and Disorders. Heat Shock Protein 90 in Human Diseases and Disorders 19 45 .
Rajnish Kumar, Bengt Winblad & Pavel F. Pavlov. 2019. Heat Shock Protein 90 in Human Diseases and Disorders. Heat Shock Protein 90 in Human Diseases and Disorders 281 295 .
Margaret M. Centenera, Luke A. Selth, Esmaeil Ebrahimie, Lisa M. Butler & Wayne D. Tilley. (2018) New Opportunities for Targeting the Androgen Receptor in Prostate Cancer. Cold Spring Harbor Perspectives in Medicine 8:12, pages a030478.
Crossref
Alexandra Bernadotte, Rajnish Kumar, Bengt Winblad & Pavel F. Pavlov. (2018) In silico identification and biochemical characterization of the human dicarboxylate clamp TPR protein interaction network . FEBS Open Bio 8:11, pages 1830-1843.
Crossref
P. N. Surkin, H. Brenhouse, T. Deak, A. C. Liberman & M. Lasaga. (2018) Stress, alcohol and infection during early development: A brief review of common outcomes and mechanisms. Journal of Neuroendocrinology 30:10, pages e12602.
Crossref
Zhonglin Cai, Weijie Chen, Jianzhong Zhang & Hongjun Li. (2018) Androgen receptor: what we know and what we expect in castration-resistant prostate cancer. International Urology and Nephrology 50:10, pages 1753-1764.
Crossref
Ying Gao, Elham Elamin, Rongfang Zhou, Huili Yan, Shuang Liu, Shengnan Hu, Jing Dong, Muyun Wei, Linying Sun & Yueran Zhao. (2018) FKBP51 promotes migration and invasion of papillary thyroid carcinoma through NF‑κB‑dependent epithelial‑to‑mesenchymal transition. Oncology Letters.
Crossref
Shoko Matsushita, Kentaro Suzuki, Aki Murashima, Daiki Kajioka, Alvin Resultay Acebedo, Shinichi Miyagawa, Ryuma Haraguchi, Yukiko Ogino & Gen Yamada. (2018) Regulation of masculinization: androgen signalling for external genitalia development. Nature Reviews Urology 15:6, pages 358-368.
Crossref
Marek Orłowski, Katarzyna Popławska, Joanna Pieprzyk, Aleksandra Szczygieł-Sommer, Anna Więch, Mirosław Zarębski, Aneta Tarczewska, Jurek Dobrucki & Andrzej Ożyhar. (2018) Molecular determinants of Drosophila immunophilin FKBP39 nuclear localization . Biological Chemistry 399:5, pages 467-484.
Crossref
Yiqiao Huang, Xianhan Jiang, Xue Liang & Ganggang Jiang. (2018) Molecular and cellular mechanisms of castration resistant prostate cancer (Review). Oncology Letters.
Crossref
Gisela I. Mazaira, Cristina Daneri-Becerra, Nadia R. Zgajnar, Cecilia M. Lotufo & Mario D. Galigniana. (2018) Gene expression regulation by heat-shock proteins: the cardinal roles of HSF1 and Hsp90. Biochemical Society Transactions 46:1, pages 51-65.
Crossref
Philipp Y Maximov, Balkees Abderrahman, Ramona F Curpan, Yousef M Hawsawi, Ping Fan & V Craig Jordan. (2018) A unifying biology of sex steroid-induced apoptosis in prostate and breast cancers. Endocrine-Related Cancer 25:2, pages R83-R113.
Crossref
Holger Barth & Katharina Ernst. 2018. Microbial Toxins. Microbial Toxins 331 352 .
Paolo D’Arrigo, Martina Tufano, Anna Rea, Simona Romano & Maria Fiammetta Romano. 2018. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules 1737 1767 .
Gabriel Fries, Nils Gassen & Theo Rein. (2017) The FKBP51 Glucocorticoid Receptor Co-Chaperone: Regulation, Function, and Implications in Health and Disease. International Journal of Molecular Sciences 18:12, pages 2614.
Crossref
Arash Nabbi, Urszula L. McClurg, Subhash Thalappilly, Amal Almami, Mahsa Mobahat, Tarek A. Bismar, Olivier Binda & Karl T. Riabowol. (2017) ING3 promotes prostate cancer growth by activating the androgen receptor. BMC Medicine 15:1.
Crossref
Jing Dong, Yulian Jiao, Wenli Mu, Bingru Lu, Muyun Wei, Linying Sun, Shengnan Hu, Bin Cui, Xiaowen Liu, Zijiang Chen & Yueran Zhao. (2017) FKBP51 decreases cell proliferation and increases progestin sensitivity of human endometrial adenocarcinomas by inhibiting Akt. Oncotarget 8:46, pages 80405-80415.
Crossref
Miho Takaoka, Shun Ito, Yoshio Miki & Akira Nakanishi. (2017) FKBP51 regulates cell motility and invasion via RhoA signaling. Cancer Science 108:3, pages 380-389.
Crossref
Mary Nakazawa, Channing Paller & Natasha Kyprianou. (2017) Mechanisms of Therapeutic Resistance in Prostate Cancer. Current Oncology Reports 19:2.
Crossref
Heather K. Armstrong, Yen Chin Koay, Swati Irani, Rajdeep Das, Zeyad D. Nassar, Luke A. Selth, Margaret M. Centenera, Shelli R. McAlpine & Lisa M. Butler. (2016) A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response. The Prostate 76:16, pages 1546-1559.
Crossref
Julie A Pollock, Suzanne E Wardell, Alexander A Parent, David B Stagg, Stephanie J Ellison, Holly M Alley, Christina A Chao, Scott A Lawrence, James P Stice, Ivan Spasojevic, Jennifer G Baker, Sung Hoon Kim, Donald P McDonnell, John A Katzenellenbogen & John D Norris. (2016) Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer. Nature Chemical Biology 12:10, pages 795-801.
Crossref
M Antunica-Noguerol, M L Budziñski, J Druker, N C Gassen, M C Sokn, S Senin, F Aprile-Garcia, F Holsboer, T Rein, A C Liberman & E Arzt. (2016) The activity of the glucocorticoid receptor is regulated by SUMO conjugation to FKBP51. Cell Death & Differentiation 23:10, pages 1579-1591.
Crossref
Cameron M. Armstrong & Allen C. Gao. (2016) Adaptive pathways and emerging strategies overcoming treatment resistance in castration resistant prostate cancer. Asian Journal of Urology 3:4, pages 185-194.
Crossref
Mariana Lagadari, Nadia R. Zgajnar, Luciana I. Gallo & Mario D. Galigniana. (2016) Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity. Molecular Oncology 10:7, pages 1086-1098.
Crossref
Eric Biron & François Bédard. (2016) Recent progress in the development of protein–protein interaction inhibitors targeting androgen receptor–coactivator binding in prostate cancer. The Journal of Steroid Biochemistry and Molecular Biology 161, pages 36-44.
Crossref
Dan Wu, Xuanyu Tao, Zhi-Peng Chen, Jian-Ting Han, Wen-Juan Jia, Ning Zhu, Xiangkai Li, Zhiping Wang & Yong-Xing He. (2016) The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells. Journal of Hazardous Materials 307, pages 193-201.
Crossref
Gisela I. Mazaira, María F. Camisay, Sonia De Leo, Alejandra G. Erlejman & Mario D. Galigniana. (2016) Biological relevance of Hsp90-binding immunophilins in cancer development and treatment. International Journal of Cancer 138:4, pages 797-808.
Crossref
Takashi Kawahara, Eiji Kashiwagi, Yi Li, Yichun Zheng, Yurina Miyamoto, George J. Netto, Hitoshi Ishiguro & Hiroshi Miyamoto. (2016) Cyclosporine A and tacrolimus inhibit urothelial tumorigenesis. Molecular Carcinogenesis 55:2, pages 161-169.
Crossref
Holger Barth & Katharina Ernst. 2016. Microbial Toxins. Microbial Toxins 1 22 .
Paolo D’Arrigo, Martina Tufano, Anna Rea, Simona Romano & Maria Fiammetta Romano. 2016. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules 1 31 .
Simona Romano, Anna D’Angelillo & Maria Fiammetta Romano. (2015) Pleiotropic roles in cancer biology for multifaceted proteins FKBPs. Biochimica et Biophysica Acta (BBA) - General Subjects 1850:10, pages 2061-2068.
Crossref
L Wang, G Song, X Chang, W Tan, J Pan, X Zhu, Z Liu, M Qi, J Yu & B Han. (2014) The role of TXNDC5 in castration-resistant prostate cancer—involvement of androgen receptor signaling pathway. Oncogene 34:36, pages 4735-4745.
Crossref
Kalpit Shah & Neil A. Bradbury. (2015) Lemur Tyrosine Kinase 2, a novel target in prostate cancer therapy. Oncotarget 6:16, pages 14233-14246.
Crossref
Laura Nelson, Hayley D. McKeen, Andrea Marshall, Laoighse Mulrane, Jane Starczynski, Sarah J. Storr, Fiona Lanigan, Christopher Byrne, Ken Arthur, Shauna Hegarty, Ahlam Abdunnabi Ali, Fiona Furlong, Helen O. McCarthy, Ian O. Ellis, Andrew R. Green, Emad Rakha, Leonie Young, Ian Kunkler, Jeremy Thomas, Wilma Jack, David Cameron, Karin Jirström, Anita Yakkundi, Lana McClements, Stewart G. Martin, William M. Gallagher, Janet Dunn, John Bartlett, Darran O’Connor & Tracy Robson. (2015) FKBPL: a marker of good prognosis in breast cancer. Oncotarget 6:14, pages 12209-12223.
Crossref
Holger Barth, Bradley G. Stiles & Michel R. Popoff. 2015. The Comprehensive Sourcebook of Bacterial Protein Toxins. The Comprehensive Sourcebook of Bacterial Protein Toxins 397 425 .
Naihsuan C. Guy, Yenni A. Garcia, Jeffrey C. Sivils, Mario D. Galigniana & Marc B. Cox. 2015. The Networking of Chaperones by Co-chaperones. The Networking of Chaperones by Co-chaperones 35 68 .
Nian-Kang Sun, Shang-Lang Huang, Pu-Yuan Chang, Hsing-Pang Lu & Chuck C.-K. Chao. (2014) Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response. Oncotarget 5:23, pages 11939-11956.
Crossref
Hátylas Azevedo, André Fujita, Silvia Yumi Bando, Priscila Iamashita & Carlos Alberto Moreira-Filho. (2014) Transcriptional Network Analysis Reveals that AT1 and AT2 Angiotensin II Receptors Are Both Involved in the Regulation of Genes Essential for Glioma Progression. PLoS ONE 9:11, pages e110934.
Crossref
Zoran Culig & Frédéric R. Santer. (2014) Androgen receptor signaling in prostate cancer. Cancer and Metastasis Reviews 33:2-3, pages 413-427.
Crossref
Sourajit M. MustafiDavid M. LeMasterGriselda Hernández. (2014) Differential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52. Biochemical Journal 461:1, pages 115-123.
Crossref
C Donley, K McClelland, H D McKeen, L Nelson, A Yakkundi, P V Jithesh, J Burrows, L McClements, A Valentine, K M Prise, H O McCarthy & T Robson. (2013) Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen. Oncogene 33:26, pages 3441-3450.
Crossref
Clarissa Velayo, Takuya Ito, Yupeng Dong, Miyuki Endo, Rika Sugibayashi, Kiyoe Funamoto, Keita Iida, Nobuo Yaegashi & Yoshitaka Kimura. (2014) Molecular Patterns of Neurodevelopmental Preconditioning: A Study of the Effects of Antenatal Steroid Therapy in a Protein-Restriction Mouse Model. ISRN Obstetrics and Gynecology 2014, pages 1-13.
Crossref
Carmel Pezaro, Aurelius Omlin, Diletta Bianchini & Johann de Bono. 2014. Prostate Cancer. Prostate Cancer 265 286 .
G. I. Mazaira, M. Lagadari, A. G. Erlejman & M. D. Galigniana. (2014) The Emerging Role of TPR-Domain Immunophilins in the Mechanism of Action of Steroid Receptors. Nuclear Receptor Research 1, pages 1-17.
Crossref
Ekaterina Petrovich, Carol Asher & Haim Garty. (2014) Induction of FKBP51 by aldosterone in intestinal epithelium. The Journal of Steroid Biochemistry and Molecular Biology 139, pages 78-87.
Crossref
Siu Chiu Chan & Scott M. Dehm. 2014. Pharmacology & Therapeutics of Constitutively Active Receptors. Pharmacology & Therapeutics of Constitutively Active Receptors 327 366 .
Carmel Pezaro, Aurelius Omlin, David Lorente & Johann de Bono. (2013) Management of Patients with Castration-Resistant Disease. Hematology/Oncology Clinics of North America 27:6, pages 1243-1260.
Crossref
Lisa K. Philp, Miriam S. Butler, Theresa E. Hickey, Lisa M. Butler, Wayne D. Tilley & Tanya K. Day. (2013) SGTA: A New Player in the Molecular Co-Chaperone Game. Hormones and Cancer 4:6, pages 343-357.
Crossref
Chih-Chao Hsu & Chang-Deng Hu. (2013) Transcriptional activity of c-Jun is critical for the suppression of AR function. Molecular and Cellular Endocrinology 372:1-2, pages 12-22.
Crossref
Joanna L. GillisLuke A. SelthMargaret M. CenteneraScott L. TownleyShihua SunStephen R. PlymateWayne D. TilleyLisa M. Butler. (2013) Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors. Oncotarget 4:5, pages 691-704.
Crossref
Laia Querol Cano, Derek N. Lavery & Charlotte L. Bevan. (2013) Mini-review: Foldosome regulation of androgen receptor action in prostate cancer. Molecular and Cellular Endocrinology 369:1-2, pages 52-62.
Crossref
Anne-Katrin Fabian, Andreas März, Sonja Neimanis, Ricardo M. Biondi, Christian Kozany & Felix Hausch. (2013) InterAKTions with FKBPs - Mutational and Pharmacological Exploration. PLoS ONE 8:2, pages e57508.
Crossref
Stuart K. Calderwood. (2013) Molecular Cochaperones: Tumor Growth and Cancer Treatment. Scientifica 2013, pages 1-13.
Crossref
Simona Romano, Rita Bisogni & Maria Fiammetta Romano. 2013. Prostate Cancer: Shifting from Morphology to Biology. Prostate Cancer: Shifting from Morphology to Biology 79 86 .
Holger Barth. 2013. Moonlighting Cell Stress Proteins in Microbial Infections. Moonlighting Cell Stress Proteins in Microbial Infections 251 265 .
Junkui Ai & Zhou Wang. 2013. Prostate Cancer. Prostate Cancer 443 459 .
Alexandra Kollara & Theodore J. Brown. (2012) Expression and function of nuclear receptor co-activator 4: evidence of a potential role independent of co-activator activity. Cellular and Molecular Life Sciences 69:23, pages 3895-3909.
Crossref
Eva Kaiser, Natalie Böhm, Katharina Ernst, Simon Langer, Carsten Schwan, Klaus Aktories, Michel Popoff, Gunter FischerHolger Barth. (2012) FK506‐binding protein 51 interacts with Clostridium botulinum C2 toxin and FK506 inhibits membrane translocation of the toxin in mammalian cells . Cellular Microbiology 14:8, pages 1193-1205.
Crossref
Mathias V. Schmidt, Marcelo Paez-Pereda, Florian Holsboer & Felix Hausch. (2012) The Prospect of FKBP51 as a Drug Target. ChemMedChem 7:8, pages 1351-1359.
Crossref
Ranganath Gopalakrishnan, Christian Kozany, Steffen Gaali, Christoph Kress, Bastiaan Hoogeland, Andreas Bracher & Felix Hausch. (2012) Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52. Journal of Medicinal Chemistry 55:9, pages 4114-4122.
Crossref
Edwin R. Sanchez. (2012) Chaperoning steroidal physiology: Lessons from mouse genetic models of Hsp90 and its cochaperones. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823:3, pages 722-729.
Crossref
David DilworthGeoff GudaviciusAndrew LeungChristopher J. Nelson. (2012) The roles of peptidyl-proline isomerases in gene regulation 1 This review is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal’s usual peer review process. . Biochemistry and Cell Biology 90:1, pages 55-69.
Crossref
Iain J. McEwan. (2012) Intrinsic disorder in the androgen receptor: identification, characterisation and drugability. Mol. BioSyst. 8:1, pages 82-90.
Crossref
Sophie E. Jackson. 2013. Molecular Chaperones. Molecular Chaperones 155 240 .
Cheryl L. Storer, Chad A. Dickey, Mario D. Galigniana, Theo Rein & Marc B. Cox. (2011) FKBP51 and FKBP52 in signaling and disease. Trends in Endocrinology & Metabolism 22:12, pages 481-490.
Crossref
John C. O'Leary, Sheetal Dharia, Laura J. Blair, Sarah Brady, Amelia G. Johnson, Melinda Peters, Joyce Cheung-Flynn, Marc B. Cox, Gabriel de Erausquin, Edwin J. Weeber, Umesh K. Jinwal & Chad A. Dickey. (2011) A New Anti-Depressive Strategy for the Elderly: Ablation of FKBP5/FKBP51. PLoS ONE 6:9, pages e24840.
Crossref
Bo-Hwa Choi & Ho Sup Yoon. (2011) FKBP38-Bcl-2 interaction: a novel link to chemoresistance. Current Opinion in Pharmacology 11:4, pages 354-359.
Crossref
Lance A Stechschulte & Edwin R Sanchez. (2011) FKBP51—a selective modulator of glucocorticoid and androgen sensitivity. Current Opinion in Pharmacology 11:4, pages 332-337.
Crossref
Tiina Jääskeläinen, Harri Makkonen & Jorma J Palvimo. (2011) Steroid up-regulation of FKBP51 and its role in hormone signaling. Current Opinion in Pharmacology 11:4, pages 326-331.
Crossref
Jérôme Solassol, Alain Mange & Thierry Maudelonde. (2011) FKBP family proteins as promising new biomarkers for cancer. Current Opinion in Pharmacology 11:4, pages 320-325.
Crossref
Liewei Wang. (2011) FKBP51 regulation of AKT/protein kinase B phosphorylation. Current Opinion in Pharmacology 11:4, pages 360-364.
Crossref
Ya-Li Yao, Ya-Chen Liang, Huai-Huei Huang & Wen-Ming Yang. (2011) FKBPs in chromatin modification and cancer. Current Opinion in Pharmacology 11:4, pages 301-307.
Crossref
Melanie Gerard, Angélique Deleersnijder, Jonas Demeulemeester, Zeger Debyser & Veerle Baekelandt. (2011) Unraveling the Role of Peptidyl-Prolyl Isomerases in Neurodegeneration. Molecular Neurobiology 44:1, pages 13-27.
Crossref
Johanny Tonos De LeonAki IwaiClementine FeauYenni GarciaHeather A. BalsigerCheryl L. StorerRaquel M. SuroKristine M. GarzaSunmin LeeYeong Sang KimYu ChenYang-Min NingDaniel L. Riggs, Robert J. Fletterick, R. Kiplin GuyJane B. TrepelLeonard M. NeckersMarc B. Cox. (2011) Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells. Proceedings of the National Academy of Sciences 108:29, pages 11878-11883.
Crossref
Rudi Kenneth Allan & Thomas Ratajczak. (2010) Versatile TPR domains accommodate different modes of target protein recognition and function. Cell Stress and Chaperones 16:4, pages 353-367.
Crossref
Kristin R. Lamont & Donald J. Tindall. (2011) Minireview: Alternative Activation Pathways for the Androgen Receptor in Prostate Cancer. Molecular Endocrinology 25:6, pages 897-907.
Crossref
Andreas Bracher, Christian Kozany, Ann-Katrin Thost & Felix Hausch. (2011) Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90. Acta Crystallographica Section D Biological Crystallography 67:6, pages 549-559.
Crossref
Hayley D. McKeenDonal J. Brennan, Shauna HegartyFiona Lanigan, Karin Jirstrom, Christopher ByrneAnita YakkundiHelen O. McCarthyWilliam M. Gallagher & Tracy Robson. (2011) The emerging role of FK506-binding proteins as cancer biomarkers: a focus on FKBPL. Biochemical Society Transactions 39:2, pages 663-668.
Crossref
L Li, Z Lou & L Wang. (2010) The role of FKBP5 in cancer aetiology and chemoresistance. British Journal of Cancer 104:1, pages 19-23.
Crossref
Jan-Philip Schülke, Gabriela Monika Wochnik, Isabelle Lang-Rollin, Nils Christian Gassen, Regina Theresia Knapp, Barbara Berning, Alexander Yassouridis & Theo Rein. (2010) Differential Impact of Tetratricopeptide Repeat Proteins on the Steroid Hormone Receptors. PLoS ONE 5:7, pages e11717.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.