33
Views
62
CrossRef citations to date
0
Altmetric
Article

Epidermal Growth Factor-Like Domain Repeat of Stabilin-2 Recognizes Phosphatidylserine during Cell Corpse Clearance

, , , &
Pages 5288-5298 | Received 06 Nov 2007, Accepted 13 Jun 2008, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Fiona Y. Glassman, Robert Dingman, Helena C. Yau & Sathy V. Balu-Iyer. (2020) Biological Function and Immunotherapy Utilizing Phosphatidylserine-based Nanoparticles. Immunological Investigations 49:7, pages 858-874.
Read now
Vijay Kumar. (2020) Phagocytosis: Phenotypically Simple Yet a Mechanistically Complex Process. International Reviews of Immunology 39:3, pages 118-150.
Read now
Soyoun Kim, Seung-Yoon Park, Sang-Yeob Kim, Dong-Jun Bae, Jae-Hoon Pyo, Mina Hong & In-San Kim. (2012) Cross Talk between Engulfment Receptors Stabilin-2 and Integrin αvβ5 Orchestrates Engulfment of Phosphatidylserine-Exposed Erythrocytes. Molecular and Cellular Biology 32:14, pages 2698-2708.
Read now
Jeong H Yun, Peter M Henson & Rubin M Tuder. (2008) Phagocytic clearance of apoptotic cells: role in lung disease. Expert Review of Respiratory Medicine 2:6, pages 753-765.
Read now

Articles from other publishers (58)

Zsuzsa Szondy, Nour Al‐Zaeed, Nastaran Tarban, Éva Fige, Éva Garabuczi & Zsolt Sarang. (2022) Involvement of phosphatidylserine receptors in the skeletal muscle regeneration: therapeutic implications. Journal of Cachexia, Sarcopenia and Muscle 13:4, pages 1961-1973.
Crossref
Changrong Ge, Dongmei Tong, Erik Lönnblom, Bibo Liang, Weiwei Cai, Cecilia Fahlquist‐Hagert, Taotao Li, Alf Kastbom, Inger Gjertsson, Doreen Dobritzsch & Rikard Holmdahl. (2022) Antibodies to Cartilage Oligomeric Matrix Protein Are Pathogenic in Mice and May Be Clinically Relevant in Rheumatoid Arthritis. Arthritis & Rheumatology 74:6, pages 961-971.
Crossref
Aleksandra Twarda-Clapa, Aleksandra Olczak, Aneta M. Białkowska & Maria Koziołkiewicz. (2022) Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs. Cells 11:8, pages 1312.
Crossref
Jiao Wang, Changxin Yu, Junyi Zhuang, Wenxin Qi, Jiawen Jiang, Xuanting Liu, Wanwei Zhao, Yiyang Cao, Hao Wu, Jingxuan Qi & Robert Chunhua Zhao. (2022) The role of phosphatidylserine on the membrane in immunity and blood coagulation. Biomarker Research 10:1.
Crossref
Jie Zhang, Zhujiang Dai, Cheng Yan, Daorong Wang & Dong Tang. (2021) Blocking antibody-mediated phosphatidylserine enhances cancer immunotherapy. Journal of Cancer Research and Clinical Oncology 147:12, pages 3639-3651.
Crossref
Marc Tollis, Elliott Ferris, Michael S Campbell, Valerie K Harris, Shawn M Rupp, Tara M Harrison, Wendy K Kiso, Dennis L Schmitt, Michael M Garner, Christina Athena Aktipis, Carlo C Maley, Amy M Boddy, Mark Yandell, Christopher Gregg, Joshua D Schiffman & Lisa M Abegglen. (2021) Elephant Genomes Reveal Accelerated Evolution in Mechanisms Underlying Disease Defenses. Molecular Biology and Evolution 38:9, pages 3606-3620.
Crossref
Tom O. J. Cockram, Jacob M. Dundee, Alma S. Popescu & Guy C. Brown. (2021) The Phagocytic Code Regulating Phagocytosis of Mammalian Cells. Frontiers in Immunology 12.
Crossref
Austin Le Lam & Bryan Heit. (2021) Having an Old Friend for Dinner: The Interplay between Apoptotic Cells and Efferocytes. Cells 10:5, pages 1265.
Crossref
Edward N. Harris & Erika Baker. (2020) Role of the Hyaluronan Receptor, Stabilin-2/HARE, in Health and Disease. International Journal of Molecular Sciences 21:10, pages 3504.
Crossref
Jen-Hwey Chiu, Ling-Ming Tseng, Tzu-Ting Huang, Chun-Yu Liu, Jir-You Wang, Ching-Po Huang, Yi-Fang Tsai & Chih-Yi Hsu. (2020) MEGF11 is related to tumour recurrence in triple negative breast cancer via chemokine upregulation. Scientific Reports 10:1.
Crossref
Mengke Shi, Shigui Jiang, Yundong Li, Qibin Yang, Song Jiang, Lishi Yang, Jianhua Huang & Falin Zhou. (2020) Comprehensive expression analysis of the beta integrin from Penaeus monodon indicating its participation in innate immunity and ammonia nitrogen stress response. Fish & Shellfish Immunology 98, pages 887-898.
Crossref
Anna‐Lena Bollinger, Thomas Bollinger, Jan Rupp, Kensuke Shima, Natalie Gross, Laura Padayachy, Rachel Chicheportiche, Gisella L. Puga Yung & Jörg Dieter Seebach. (2019) Annexin V expression on CD4 + T cells with regulatory function . Immunology 159:2, pages 205-220.
Crossref
Dong-Jun Bae, Junyoung Seo, Sang-Yeob Kim, Seung-Yoon Park, Jae Do Yoo, Jae-Hoon Pyo, Wonhwa Cho, Je-Yoel Cho, Soyoun Kim & In-San Kim. (2019) ArhGAP12 plays dual roles in Stabilin-2 mediated efferocytosis: Regulates Rac1 basal activity and spatiotemporally turns off the Rac1 to orchestrate phagosome maturation. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1866:10, pages 1595-1607.
Crossref
Weigel. (2019) Discovery of the Liver Hyaluronan Receptor for Endocytosis (HARE) and Its Progressive Emergence as the Multi-Ligand Scavenger Receptor Stabilin-2. Biomolecules 9:9, pages 454.
Crossref
Seung-Yoon Park & In-San Kim. (2019) Stabilin Receptors: Role as Phosphatidylserine Receptors. Biomolecules 9:8, pages 387.
Crossref
Soon-Young Kim, Eun-Hye Lee, Seung-Yoon Park, Hyuck Choi, Jeong-Tae Koh, Eui Kyun Park, In-San Kim & Jung-Eun Kim. (2019) Ablation of Stabilin-1 Enhances Bone-Resorbing Activity in Osteoclasts In Vitro. Calcified Tissue International 105:2, pages 205-214.
Crossref
Patten & Shetty. (2019) The Role of Stabilin-1 in Lymphocyte Trafficking and Macrophage Scavenging in the Liver Microenvironment. Biomolecules 9:7, pages 283.
Crossref
Daniel A. Patten & Shishir Shetty. (2018) More Than Just a Removal Service: Scavenger Receptors in Leukocyte Trafficking. Frontiers in Immunology 9.
Crossref
Noumeira Hamoud, Viviane Tran, Takahiro Aimi, Wataru Kakegawa, Sylvie Lahaie, Marie-Pier Thibault, Ariane Pelletier, G. William Wong, In-San Kim, Artur Kania, Michisuke Yuzaki, Michel Bouvier & Jean-François Côté. (2018) Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion. Nature Communications 9:1.
Crossref
Aleksandra Twarda-Clapa, Beata Labuzek, Dobroslawa Krzemien, Bogdan Musielak, Przemyslaw Grudnik, Grzegorz Dubin & Tad A. Holak. (2018) Crystal structure of the FAS1 domain of the hyaluronic acid receptor stabilin-2. Acta Crystallographica Section D Structural Biology 74:7, pages 695-701.
Crossref
Colton M. MillerMichael TanowitzAaron J. DonnerThazha P. PrakashEric E. SwayzeEdward N. HarrisPunit P. Seth. (2018) Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver. Nucleic Acid Therapeutics 28:3, pages 119-127.
Crossref
Scott P. Davies, Gary M. Reynolds & Zania Stamataki. (2018) Clearance of Apoptotic Cells by Tissue Epithelia: A Putative Role for Hepatocytes in Liver Efferocytosis. Frontiers in Immunology 9.
Crossref
Ayesha Murshid, Jimmy Theriault, Jianlin Gong & Stuart K. Calderwood. 2018. Chaperones. Chaperones 331 344 .
Seung-Yoon Park & In-San Kim. (2017) Engulfment signals and the phagocytic machinery for apoptotic cell clearance. Experimental & Molecular Medicine 49:5, pages e331-e331.
Crossref
Sang-Yeob Kim, Soyoun Kim, Dong-Jun Bae, Seung-Yoon Park, Ga-Young Lee, Gyeong-Min Park & In-San Kim. (2017) Coordinated balance of Rac1 and RhoA plays key roles in determining phagocytic appetite. PLOS ONE 12:4, pages e0174603.
Crossref
Edward N. Harris & Justin L. Mott. 2017. Molecules, Systems and Signaling in Liver Injury. Molecules, Systems and Signaling in Liver Injury 1 21 .
Tsuneya Ikezu. 2017. Neuroimmune Pharmacology. Neuroimmune Pharmacology 245 260 .
Madhu S. Pandey, Colton M. Miller, Edward N. Harris & Paul H. Weigel. (2016) Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs. PLOS ONE 11:4, pages e0154124.
Crossref
Edouard M. Bevers & Patrick L. Williamson. (2016) Getting to the Outer Leaflet: Physiology of Phosphatidylserine Exposure at the Plasma Membrane. Physiological Reviews 96:2, pages 605-645.
Crossref
Seung-Yoon Park, Youngeun Yun, Jung-Suk Lim, Mi-Jin Kim, Sang-Yeob Kim, Jung-Eun Kim & In-San Kim. (2016) Stabilin-2 modulates the efficiency of myoblast fusion during myogenic differentiation and muscle regeneration. Nature Communications 7:1.
Crossref
Teresa Garcia-Aguilar, Patricia Espinosa-Cueto, Alejandro Magallanes-Puebla & Raúl Mancilla. (2016) The Mannose Receptor Is Involved in the Phagocytosis of Mycobacteria-Induced Apoptotic Cells. Journal of Immunology Research 2016, pages 1-14.
Crossref
Kristen K. Penberthy & Kodi S. Ravichandran. (2016) Apoptotic cell recognition receptors and scavenger receptors. Immunological Reviews 269:1, pages 44-59.
Crossref
D.B. Vaught, J.C. Stanford & R.S. Cook. 2016. Encyclopedia of Cell Biology. Encyclopedia of Cell Biology 178 183 .
D.B. Vaught, J.C. Stanford & R.S. Cook. 2016. Encyclopedia of Cell Biology. Encyclopedia of Cell Biology 374 378 .
Jianyu He, Wei Liu, Shaoping Wang, Wan Liu & Huihui Liu. (2015) The SREC-I and SREC-II associated with epidermal growth factor in scavenger receptor family are the potential regulative transmembrane receptors in Larimichthys crocea. Fish & Shellfish Immunology 47:1, pages 182-195.
Crossref
Soyoun Kim, Sang Mun Bae, Junyoung Seo, Kiweon Cha, Meilan Piao, Sun-Ji Kim, Hye-Nam Son, Rang-Woon Park, Byung-Heon Lee & In-San Kim. (2015) Advantages of the Phosphatidylserine-Recognizing Peptide PSP1 for Molecular Imaging of Tumor Apoptosis Compared with Annexin V. PLOS ONE 10:3, pages e0121171.
Crossref
Madhu S. Pandey, Edward N. Harris & Paul H. Weigel. (2015) HARE-Mediated Endocytosis of Hyaluronan and Heparin Is Targeted by Different Subsets of Three Endocytic Motifs. International Journal of Cell Biology 2015, pages 1-12.
Crossref
Amanda K. Hare & Edward N. Harris. (2015) Tissue-specific splice variants of HARE/Stabilin-2 are expressed in bone marrow, lymph node, and spleen. Biochemical and Biophysical Research Communications 456:1, pages 257-261.
Crossref
Jin Chen, Yi Zhao & Yi Liu. (2014) The Role of Nucleotides and Purinergic Signaling in Apoptotic Cell Clearance – Implications for Chronic Inflammatory Diseases. Frontiers in Immunology 5.
Crossref
Sven Moller-Tank & Wendy Maury. (2014) Phosphatidylserine receptors: Enhancers of enveloped virus entry and infection. Virology 468-470, pages 565-580.
Crossref
Ivan K. H. Poon, Christopher D. Lucas, Adriano G. Rossi & Kodi S. Ravichandran. (2014) Apoptotic cell clearance: basic biology and therapeutic potential. Nature Reviews Immunology 14:3, pages 166-180.
Crossref
A.P. Das, P.S. Kumar & S. Swain. (2014) Recent advances in biosensor based endotoxin detection. Biosensors and Bioelectronics 51, pages 62-75.
Crossref
Mona Biermann, Christian Maueröder, Jan M Brauner, Ricardo Chaurio, Christina Janko, Martin Herrmann & Luis E Muñoz. (2013) Surface code—biophysical signals for apoptotic cell clearance. Physical Biology 10:6, pages 065007.
Crossref
Shilpa D’Souza, Seung-Yoon Park & In-San Kim. (2013) Stabilin-2 acts as an engulfment receptor for the phosphatidylserine-dependent clearance of primary necrotic cells. Biochemical and Biophysical Research Communications 432:3, pages 412-417.
Crossref
Jason G. Kay & Sergio Grinstein. 2013. Lipid-mediated Protein Signaling. Lipid-mediated Protein Signaling 177 193 .
Hsiao-Han Hsieh, Tsung-Yuan Hsu, Hang-Shiang Jiang & Yi-Chun Wu. (2012) Integrin α PAT-2/CDC-42 Signaling Is Required for Muscle-Mediated Clearance of Apoptotic Cells in Caenorhabditis elegans. PLoS Genetics 8:5, pages e1002663.
Crossref
Seung-Yoon Park, Dong-Jun Bae, Mi-Jin Kim, Mei Lan Piao & In-San Kim. (2012) Extracellular Low pH Modulates Phosphatidylserine-dependent Phagocytosis in Macrophages by Increasing Stabilin-1 Expression. Journal of Biological Chemistry 287:14, pages 11261-11271.
Crossref
M. Lourdes Sampietro, Stella Trompet, Jeffrey J.W. Verschuren, Rudolf P. Talens, Joris Deelen, Bastiaan T. Heijmans, Robbert J. de Winter, Rene A. Tio, Pieter A.F.M. Doevendans, Santhi K. Ganesh, Elizabeth G. Nabel, Harm-Jan Westra, Lude Franke, Erik B. van den Akker, Rudi G.J. Westendorp, Aeilko H. Zwinderman, Adnan Kastrati, Werner Koch, P.Eline Slagboom, Peter de Knijff & J. Wouter Jukema. (2011) A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention. Human Molecular Genetics 20:23, pages 4748-4757.
Crossref
Yoshinobu Nakanishi, Kaz Nagaosa & Akiko Shiratsuchi. (2011) Phagocytic removal of cells that have become unwanted: Implications for animal development and tissue homeostasis. Development, Growth & Differentiation 53:2, pages 149-160.
Crossref
Ayesha Murshid, Jimmy Theriault, Jianlin Gong & Stuart K. Calderwood. 2011. Molecular Chaperones. Molecular Chaperones 289 302 .
E. N. Harris, S. Parry, M. Sutton-Smith, M. S. Pandey, M. Panico, H. R. Morris, S. M. Haslam, A. Dell & P. H. Weigel. (2010) N-Glycans on the link domain of human HARE/Stabilin-2 are needed for hyaluronan binding to purified ecto-domain, but not for cellular endocytosis of hyaluronan. Glycobiology 20:8, pages 991-1001.
Crossref
Soyoun Kim, Dong-Jun Bae, Mina Hong, Seung-Yoon Park & In-San Kim. (2010) The conserved histidine in epidermal growth factor-like domains of stabilin-2 modulates pH-dependent recognition of phosphatidylserine in apoptotic cells. The International Journal of Biochemistry & Cell Biology 42:7, pages 1154-1163.
Crossref
Seung-Yoon Park, Sang-Yeob Kim, Kae-Bok Kang & In-San Kim. (2010) Adaptor protein GULP is involved in stabilin-1-mediated phagocytosis. Biochemical and Biophysical Research Communications 398:3, pages 467-472.
Crossref
Masahiko Yoneda, Toshiya Nakamura, Miho Murai & Hiroshi Wada. (2010) Evidence for the Heparin-Binding Ability of the Ascidian Xlink Domain and Insight into the Evolution of the Xlink Domain in Chordates. Journal of Molecular Evolution 71:1, pages 51-59.
Crossref
Marika Karikoski, Heikki Irjala, Mikael Maksimow, Mari Miiluniemi, Kaisa Granfors, Sari Hernesniemi, Kati Elima, Gerhard Moldenhauer, Kai Schledzewski, Julia Kzhyshkowska, Sergij Goerdt, Marko Salmi & Sirpa Jalkanen. (2009) Clever-1/Stabilin-1 regulates lymphocyte migration within lymphatics and leukocyte entrance to sites of inflammation. European Journal of Immunology 39:12, pages 3477-3487.
Crossref
Ricardo Chaurio, Christina Janko, Luis Muñoz, Benjamin Frey, Martin Herrmann & Udo Gaipl. (2009) Phospholipids: Key Players in Apoptosis and Immune Regulation. Molecules 14:12, pages 4892-4914.
Crossref
Seung-Yoon Park, Mi-Yeon Jung, Sung-Jin Lee, Kae-Bok Kang, Alexei Gratchev, Vladimir Riabov, Julia Kzhyshkowska & In-San Kim. (2009) Stabilin-1 mediates phosphatidylserine-dependent clearance of cell corpses in alternatively activated macrophages. Journal of Cell Science 122:18, pages 3365-3373.
Crossref
Young-Jun Park, Gang Liu, Yuko Tsuruta, Emmanuel Lorne & Edward Abraham. (2009) Participation of the urokinase receptor in neutrophil efferocytosis. Blood 114:4, pages 860-870.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.