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Molecular and Cellular Biology Volume 26, 2006 - Issue 11
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Article

Alterations in Expression and Chromatin Configuration of the Alpha Hemoglobin-Stabilizing Protein Gene in Erythroid Krüppel-Like Factor-Deficient Mice

Andre M. Pilon1 Hematopoiesis Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland20892-4442
,
Douglas G. Nilson1 Hematopoiesis Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland20892-4442
,
Dewang Zhou2 Department of Biochemistry and Molecular Genetics, School of Medicine and Dentistry, University of Alabama at Birmingham, Birmingham, Alabama35294
,
Jose Sangerman3 Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut06520-8021
,
Tim M. Townes2 Department of Biochemistry and Molecular Genetics, School of Medicine and Dentistry, University of Alabama at Birmingham, Birmingham, Alabama35294
,
David M. Bodine1 Hematopoiesis Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland20892-4442
&
Patrick G. Gallagher3 Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut06520-8021Correspondence[email protected]
 show all
Pages 4368-4377 | Received 16 Nov 2005, Accepted 06 Mar 2006, Published online: 27 Mar 2023

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Alister P. W. Funnell, Ka Sin Mak, Natalie A. Twine, Gregory J. Pelka, Laura J. Norton, Tania Radziewic, Melinda Power, Marc R. Wilkins, Kim S. Bell-Anderson, Stuart T. Fraser, Andrew C. Perkins, Patrick P. Tam, Richard C. M. Pearson & Merlin Crossley. (2013) Generation of Mice Deficient in both KLF3/BKLF and KLF8 Reveals a Genetic Interaction and a Role for These Factors in Embryonic Globin Gene Silencing. Molecular and Cellular Biology 33:15, pages 2976-2987.
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Yvette Y. Yien & James J. Bieker. (2013) EKLF/KLF1, a Tissue-Restricted Integrator of Transcriptional Control, Chromatin Remodeling, and Lineage Determination. Molecular and Cellular Biology 33:1, pages 4-13.
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Alister P. W. Funnell, Laura J. Norton, Ka Sin Mak, Jon Burdach, Crisbel M. Artuz, Natalie A. Twine, Marc R. Wilkins, Carl A. Power, Tzong-Tyng Hung, José Perdomo, Philip Koh, Kim S. Bell-Anderson, Stuart H. Orkin, Stuart T. Fraser, Andrew C. Perkins, Richard C. M. Pearson & Merlin Crossley. (2012) The CACCC-Binding Protein KLF3/BKLF Represses a Subset of KLF1/EKLF Target Genes and Is Required for Proper Erythroid Maturation In Vivo. Molecular and Cellular Biology 32:16, pages 3281-3292.
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Susanna Porcu, Maria F. Manchinu, Maria F. Marongiu, Valeria Sogos, Daniela Poddie, Isadora Asunis, Loredana Porcu, Maria G. Marini, Paolo Moi, Antonio Cao, Frank Grosveld & Maria S. Ristaldi. (2011) Klf1 Affects DNase II-Alpha Expression in the Central Macrophage of a Fetal Liver Erythroblastic Island: a Non-Cell-Autonomous Role in Definitive Erythropoiesis. Molecular and Cellular Biology 31:19, pages 4144-4154.
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Andre M. Pilon, Murat O. Arcasoy, Holly K. Dressman, Serena E. Vayda, Yelena D. Maksimova, Jose I. Sangerman, Patrick G. Gallagher & David M. Bodine. (2008) Failure of Terminal Erythroid Differentiation in EKLF-Deficient Mice Is Associated with Cell Cycle Perturbation and Reduced Expression of E2F2. Molecular and Cellular Biology 28:24, pages 7394-7401.
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Tanushri Sengupta, Ken Chen, Eric Milot & James J. Bieker. (2008) Acetylation of EKLF Is Essential for Epigenetic Modification and Transcriptional Activation of the β-Globin Locus. Molecular and Cellular Biology 28:20, pages 6160-6170.
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Miroslawa Siatecka, Li Xue & James J. Bieker. (2007) Sumoylation of EKLF Promotes Transcriptional Repression and Is Involved in Inhibition of Megakaryopoiesis. Molecular and Cellular Biology 27:24, pages 8547-8560.
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Alister P. W. Funnell, Christopher A. Maloney, Lucinda J. Thompson, Janelle Keys, Michael Tallack, Andrew C. Perkins & Merlin Crossley. (2007) Erythroid Krüppel-Like Factor Directly Activates the Basic Krüppel-Like Factor Gene in Erythroid Cells. Molecular and Cellular Biology 27:7, pages 2777-2790.
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