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Yo-Chuen Lin, Dazhen Liu, Arindam Chakraborty, Virgilia Macias, Eileen Brister, Jay Sonalkar, Linyuan Shen, Jaba Mitra, Taekjip Ha, Andre Kajdacsy-Balla, Kannanganattu V. Prasanth & Supriya G. Prasanth. (2023) DNA Damage-Induced, S-Phase Specific Phosphorylation of Orc6 is Critical for the Maintenance of Genome Stability. Molecular and Cellular Biology 43:4, pages 143-156.
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Theodore Busby, Justyna M. Meissner, Melanie L. Styers, Jay Bhatt, Akhil Kaushik, Anita B. Hjelmeland & Elizabeth Sztul. (2017) The Arf activator GBF1 localizes to plasma membrane sites involved in cell adhesion and motility. Cellular Logistics 7:2.
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Matthew W. Parker, Michael R. Botchan & James M. Berger. (2017) Mechanisms and regulation of DNA replication initiation in eukaryotes. Critical Reviews in Biochemistry and Molecular Biology 52:2, pages 107-144.
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Articles from other publishers (46)
Dazhen Liu, Jay Sonalkar & Supriya G. Prasanth. (2023) ORChestra coordinates the replication and repair music. BioEssays 45:4.
Crossref
Crossref
Yo-Chuen Lin, Dazhen Liu, Arindam Chakraborty, Lyudmila Y. Kadyrova, You Jin Song, Qinyu Hao, Jaba Mitra, Rosaline Y. C. Hsu, Mariam K. Arif, Sneha Adusumilli, Ting-Wei Liao, Taekjip Ha, Farid A. Kadyrov, Kannanganattu V. Prasanth & Supriya G. Prasanth. (2022) Orc6 is a component of the replication fork and enables efficient mismatch repair. Proceedings of the National Academy of Sciences 119:22.
Crossref
Crossref
Yo-Chuen Lin & Supriya G. Prasanth. (2021) Replication initiation: Implications in genome integrity. DNA Repair 103, pages 103131.
Crossref
Crossref
Hsiang-Chen Chou, Kuhulika Bhalla, Osama EL Demerdesh, Olaf Klingbeil, Kaarina Hanington, Sergey Aganezov, Peter Andrews, Habeeb Alsudani, Kenneth Chang, Christopher R Vakoc, Michael C Schatz, W Richard McCombie & Bruce Stillman. (2021) The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure. eLife 10.
Crossref
Crossref
Igor Chesnokov & Katarina Akhmetova. 2021. Encyclopedia of Biological Chemistry III. Encyclopedia of Biological Chemistry III
54
62
.
Maxim Balasov, Katarina Akhmetova & Igor Chesnokov. (2020)
Humanized
Drosophila
Model of the Meier-Gorlin Syndrome Reveals Conserved and Divergent Features of the Orc6 Protein
. Genetics 216:4, pages 995-1007.
Crossref
Crossref
Jiaxuan Cheng, Ningning Li, Xiaohan Wang, Jiazhi Hu, Yuanliang Zhai & Ning Gao. (2020) Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discovery 6:1.
Crossref
Crossref
Naining Xu, Yingying You, Changdong Liu, Maxim Balasov, Lee Tung Lun, Yanyan Geng, Chun Po Fung, Haitao Miao, Honglei Tian, To To Choy, Xiao Shi, Zhuming Fan, Bo Zhou, Katarina Akhmetova, Rahman Ud Din, Hongyu Yang, Quan Hao, Peiyuan Qian, Igor Chesnokov & Guang Zhu. (2020) Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA. Nucleic Acids Research 48:19, pages 11146-11161.
Crossref
Crossref
Jan Marten Schmidt & Franziska Bleichert. (2020) Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6. Nature Communications 11:1.
Crossref
Crossref
Thomas C. R. Miller, Julia Locke, Julia F. Greiwe, John F. X. Diffley & Alessandro Costa. (2019) Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM. Nature 575:7784, pages 704-710.
Crossref
Crossref
Matthew W Parker, Maren Bell, Mustafa Mir, Jonchee A Kao, Xavier Darzacq, Michael R Botchan & James M Berger. (2019) A new class of disordered elements controls DNA replication through initiator self-assembly. eLife 8.
Crossref
Crossref
Babatunde Ekundayo & Franziska Bleichert. (2019) Origins of DNA replication. PLOS Genetics 15:9, pages e1008320.
Crossref
Crossref
N. E. Vorobyeva & M. Yu. Mazina. (2019) Functions of Insulators in the Context of Modern Whole-Genome Investigations. Russian Journal of Genetics 55:2, pages 154-162.
Crossref
Crossref
Franziska Bleichert, Alexander LeitnerRuedi AebersoldMichael R. BotchanJames M. Berger. (2018) Conformational control and DNA-binding mechanism of the metazoan origin recognition complex. Proceedings of the National Academy of Sciences 115:26.
Crossref
Crossref
Franziska Bleichert, Michael R. Botchan & James M. Berger. (2017) Mechanisms for initiating cellular DNA replication. Science 355:6327.
Crossref
Crossref
Alan C. Leonard & Julia E. Grimwade. 2017. Reference Module in Life Sciences. Reference Module in Life Sciences.
Catarina A. Marques, Calvin Tiengwe, Leandro Lemgruber, Jeziel D. Damasceno, Alan Scott, Daniel Paape, Lucio Marcello & Richard McCulloch. (2016)
Diverged composition and regulation of the
Trypanosoma brucei
origin recognition complex that mediates DNA replication initiation
. Nucleic Acids Research 44:10, pages 4763-4784.
Crossref
Crossref
Maxim Balasov, Katarina Akhmetova & Igor Chesnokov. (2015)
Drosophila
model of Meier-Gorlin syndrome based on the mutation in a conserved C-Terminal domain of Orc6
. American Journal of Medical Genetics Part A 167:11, pages 2533-2540.
Crossref
Crossref
Jun Liu, Kurt Zimmer, Douglas B. Rusch, Neha Paranjape, Ram Podicheti, Haixu Tang & Brian R. Calvi. (2015)
DNA sequence templates adjacent nucleosome and ORC sites at gene amplification origins in
Drosophila
. Nucleic Acids Research 43:18, pages 8746-8761.
Crossref
Crossref
Hironori Kawakami, Eiji Ohashi, Shota Kanamoto, Toshiki Tsurimoto & Tsutomu Katayama. (2015) Specific binding of eukaryotic ORC to DNA replication origins depends on highly conserved basic residues. Scientific Reports 5:1.
Crossref
Crossref
K. A. Akhmetova, N. V. Dorogova, I. N. Chesnokov & S. A. Fedorova. (2015) Analysis of peanut gene RNAi in drosophila oogenesis. Russian Journal of Genetics 51:9, pages 847-854.
Crossref
Crossref
Franziska Bleichert, Michael R. Botchan & James M. Berger. (2015) Crystal structure of the eukaryotic origin recognition complex. Nature 519:7543, pages 321-326.
Crossref
Crossref
Katarina Akhmetova, Maxim Balasov, Richard P. H. Huijbregts & Igor Chesnokov. (2015)
Functional insight into the role of Orc6 in septin complex filament formation in
Drosophila
. Molecular Biology of the Cell 26:1, pages 15-28.
Crossref
Crossref
Franziska Bleichert, Maxim Balasov, Igor Chesnokov, Eva Nogales, Michael R Botchan & James M Berger. (2013) A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation. eLife 2.
Crossref
Crossref
Shoko Hoshina, Kei Yura, Honami Teranishi, Noriko Kiyasu, Ayumi Tominaga, Haruka Kadoma, Ayaka Nakatsuka, Tomoko Kunichika, Chikashi Obuse & Shou Waga. (2013) Human Origin Recognition Complex Binds Preferentially to G-quadruplex-preferable RNA and Single-stranded DNA. Journal of Biological Chemistry 288:42, pages 30161-30171.
Crossref
Crossref
M. Yu. Mazina, N. E. Vorobyeva & A. N. Krasnov. (2013) The ability of the Su(Hw) protein to create a platform for ORC binding does not depend on the type of surrounding chromatin. Cell and Tissue Biology 7:4, pages 362-368.
Crossref
Crossref
Alessandro CostaIris V. HoodJames M. Berger. (2013) Mechanisms for Initiating Cellular DNA Replication. Annual Review of Biochemistry 82:1, pages 25-54.
Crossref
Crossref
Nadezhda E. Vorobyeva, Marina U. Mazina, Anton K. Golovnin, Daria V. Kopytova, Dmitriy Y. Gurskiy, Elena N. Nabirochkina, Sofia G. Georgieva, Pavel G. Georgiev & Aleksey N. Krasnov. (2013) Insulator protein Su(Hw) recruits SAGA and Brahma complexes and constitutes part of Origin Recognition Complex-binding sites in the Drosophila genome. Nucleic Acids Research 41:11, pages 5717-5730.
Crossref
Crossref
Peer Papior, José M. Arteaga-Salas, Thomas Günther, Adam Grundhoff & Aloys Schepers. (2012) Open chromatin structures regulate the efficiencies of pre-RC formation and replication initiation in Epstein-Barr virus. Journal of Cell Biology 198:4, pages 509-528.
Crossref
Crossref
Igor F. Zhimulev, Elena S. Belyaeva, Tatiana Yu Vatolina & Sergey A. Demakov. (2012) Banding patterns in Drosophila melanogaster polytene chromosomes correlate with DNA-binding protein occupancy. BioEssays 34:6, pages 498-508.
Crossref
Crossref
Jun Liu, Kristopher McConnell, Michael Dixon & Brian R. Calvi. (2012)
Analysis of model replication origins in
Drosophila
reveals new aspects of the chromatin landscape and its relationship to origin activity and the prereplicative complex
. Molecular Biology of the Cell 23:1, pages 200-212.
Crossref
Crossref
Sergey A Demakov, Tatyana Yu Vatolina, Vladimir N Babenko, Valery F Semeshin, Elena S Belyaeva & Igor F Zhimulev. (2011) Protein composition of interband regions in polytene and cell line chromosomes of Drosophila melanogaster. BMC Genomics 12:1.
Crossref
Crossref
Andreas W. Thomae, Jens Baltin, Dagmar Pich, Manuel J. Deutsch, Máté Ravasz, Krisztina Zeller, Manfred Gossen, Wolfgang Hammerschmidt & Aloys Schepers. (2011) Different roles of the human Orc6 protein in the replication initiation process. Cellular and Molecular Life Sciences 68:22, pages 3741-3756.
Crossref
Crossref
Soma Ghosh, Alex P. Vassilev, Junmei Zhang, Yingming Zhao & Melvin L. DePamphilis. (2011) Assembly of the Human Origin Recognition Complex Occurs through Independent Nuclear Localization of Its Components. Journal of Biological Chemistry 286:27, pages 23831-23841.
Crossref
Crossref
Shixuan Liu, Maxim Balasov, Hongfei Wang, Lijie Wu, Igor N. Chesnokov & Yingfang Liu. (2011) Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB. Proceedings of the National Academy of Sciences 108:18, pages 7373-7378.
Crossref
Crossref
Yoav Lubelsky, Takayo Sasaki, Marjorie A. Kuipers, Isabelle Lucas, Michelle M. Le Beau, Sandra Carignon, Michelle Debatisse, Joseph A. Prinz, Jonathan H. Dennis & David M. Gilbert. (2011) Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone. Nucleic Acids Research 39:8, pages 3141-3155.
Crossref
Crossref
Zhen Shen, Kizhakke M. Sathyan, Yijie Geng, Ruiping Zheng, Arindam Chakraborty, Brian Freeman, Fei Wang, Kannanganattu V. Prasanth & Supriya G. Prasanth. (2010) A WD-Repeat Protein Stabilizes ORC Binding to Chromatin. Molecular Cell 40:1, pages 99-111.
Crossref
Crossref
Heather K. MacAlpine, Raluca Gordân, Sara K. Powell, Alexander J. Hartemink & David M. MacAlpine. (2010)
Drosophila
ORC localizes to open chromatin and marks sites of cohesin complex loading
. Genome Research 20:2, pages 201-211.
Crossref
Crossref
Mu Gao & Jeffrey Skolnick. (2009) A Threading-Based Method for the Prediction of DNA-Binding Proteins with Application to the Human Genome. PLoS Computational Biology 5:11, pages e1000567.
Crossref
Crossref
Stephen Kearsey, Judith L Campbell, Genevieve Almouzni, Joanna Poulton, Takehiro Yasukawa, Steve Bell, Ron Laskey, Tom Kunkel, James Chong, Xinquan Ge, Julian Blow, Christian Speck, Ginger Jiang, Ellen Fanning, Helle D Ulrich, Christian Haering, James Chong, Ji-Liang Li, Tracy Bryan & Alison WaltersChristian Speck & Jerzy Majka. 2009. Molecular Themes in DNA Replication. Molecular Themes in DNA Replication
22
46
.
Maxim Balasov, Richard P. H. Huijbregts & Igor Chesnokov. (2009)
Functional analysis of an Orc6 mutant in
Drosophila
. Proceedings of the National Academy of Sciences 106:26, pages 10672-10677.
Crossref
Crossref
Richard P.H. Huijbregts, Anton Svitin, Monica W. Stinnett, Matthew B. Renfrow & Igor Chesnokov. (2009)
Drosophila
Orc6 Facilitates GTPase Activity and Filament Formation of the Septin Complex
. Molecular Biology of the Cell 20:1, pages 270-281.
Crossref
Crossref
Elaine J. Gavin, Bo Song, Yuan Wang, Yaguang Xi & Jingfang Ju. (2008) Reduction of Orc6 Expression Sensitizes Human Colon Cancer Cells to 5-Fluorouracil and Cisplatin. PLoS ONE 3:12, pages e4054.
Crossref
Crossref
Joseph Ahlander, Xiao-Bo Chen & Giovanni Bosco. (2008) The N-Terminal Domain of the Drosophila Retinoblastoma Protein Rbf1 Interacts with ORC and Associates with Chromatin in an E2F Independent Manner. PLoS ONE 3:7, pages e2831.
Crossref
Crossref
Andreas W. ThomaeDagmar PichJan Brocher, Mark-Peter SpindlerChristian Berens, Robert Hock, Wolfgang HammerschmidtAloys Schepers. (2008) Interaction between HMGA1a and the origin recognition complex creates site-specific replication origins. Proceedings of the National Academy of Sciences 105:5, pages 1692-1697.
Crossref
Crossref
Shuyan Chen, Milan A. de Vries & Stephen P. Bell. (2007) Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2–7 loading. Genes & Development 21:22, pages 2897-2907.
Crossref
Crossref