30
Views
40
CrossRef citations to date
0
Altmetric
Article

Identification of a WD40 Repeat-Containing Isoform of PHIP as a Novel Regulator of β-Cell Growth and Survival

, , , , , , & show all
Pages 6484-6496 | Received 22 Dec 2006, Accepted 05 Jul 2007, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Ravi Mangal Patel & Patricia W. Lin. (2010) Developmental biology of gut-probiotic interaction. Gut Microbes 1:3, pages 186-195.
Read now

Articles from other publishers (39)

M.J. Murray, E. Bradley, Y. Ng, O. Thomas, K. Patel, C. Angus, C. Atkinson & M.B. Reeves. (2023) In silico interrogation of the miRNAome of infected hematopoietic cells to predict processes important for human cytomegalovirus latent infection. Journal of Biological Chemistry 299:6, pages 104727.
Crossref
Juan Zhang, Yan Li, Ting-yu Fan, Dan Liu, Wen-da Zou, Hui Li & Yu-kun Li. (2022) Identification of bromodomain-containing proteins prognostic value and expression significance based on a genomic landscape analysis of ovarian serous cystadenocarcinoma. Frontiers in Oncology 12.
Crossref
Neysha Tirado-Class, Caitlin Hathaway, Wendy K. Chung & Huzefa Dungrawala. (2022) PHIP variants associated with Chung–Jansen syndrome disrupt replication fork stability and genome integrity . Molecular Case Studies 8:5, pages a006212.
Crossref
Yue Shan, Shelley A. Cole, Karin Haack, Phillip E. Melton, Lyle G. Best, Christopher Bizon, Sayuko Kobes, Çiğdem Köroğlu, Leslie J. Baier, Robert L. Hanson, Serena Sanna, Yun Li & Nora Franceschini. (2022) Association of protein function-altering variants with cardiometabolic traits: the strong heart study. Scientific Reports 12:1.
Crossref
Harold Grosjean, Mehtap Işık, Anthony Aimon, David Mobley, John Chodera, Frank von Delft & Philip C Biggin. (2022) SAMPL7 protein-ligand challenge: A community-wide evaluation of computational methods against fragment screening and pose-prediction. Journal of Computer-Aided Molecular Design 36:4, pages 291-311.
Crossref
Jordan Dietrich, Scott Lovell, Olivia J. Veatch & Merlin G. Butler. (2021) PHIP gene variants with protein modeling, interactions, and clinical phenotypes . American Journal of Medical Genetics Part A 188:2, pages 579-589.
Crossref
Junjun Zhang, Liangfeng Huang, Pengfei Zhang, Xingchen Huang, Weihan Yang, Runfeng Liu, Qinqiang Sun, Yangqing Lu, Ming Zhang & Qiang Fu. (2022) Genomic Identification, Evolution, and Expression Analysis of Bromodomain Genes Family in Buffalo. Genes 13:1, pages 103.
Crossref
Sang‐Min Jang, Christophe E. Redon & Mirit I. Aladjem. (2021) Switching DCAFs: Beyond substrate receptors. BioEssays 43:7, pages 2100057.
Crossref
Harleen Kaur & Inusha Panigrahi. (2021) Chung–Jansen Syndrome with obesity. Obesity Research & Clinical Practice 15:3, pages 303-305.
Crossref
Sang-Min Jang, Christophe E. Redon, Haiqing Fu, Fred E. Indig & Mirit I. Aladjem. (2021) RepID-deficient cancer cells are sensitized to a drug targeting p97/VCP segregase. Molecular & Cellular Toxicology 17:2, pages 141-149.
Crossref
Wen Su, Yuehong Shen, Yufan Wang, Feng Wang, Xia Hong, Yuling Chen, Yuntao Lin & Hongyu Yang. (2021) RETRACTED: circPHIP promotes oral squamous cell carcinoma progression by sponging miR-142-5p and regulating PHIP and ACTN4 expression. Molecular Therapy - Nucleic Acids 23, pages 185-199.
Crossref
Steven Timmermans & Claude Libert. (2021) Ratpost: a searchable database of protein-inactivating sequence variations in 40 sequenced rat-inbred strains. Mammalian Genome 32:1, pages 1-11.
Crossref
Mohd. Muddassir, Kunjal Soni, Chetan B. Sangani, Abdullah Alarifi, Mohd. Afzal, Naaser A. Y. Abduh, Yongtao Duan & Poonam Bhadja. (2021) Bromodomain and BET family proteins as epigenetic targets in cancer therapy: their degradation, present drugs, and possible PROTACs. RSC Advances 11:2, pages 612-636.
Crossref
Arik Townsend, Gabriella Lora, Justin Engel, Neysha Tirado-Class & Huzefa Dungrawala. (2021) DCAF14 promotes stalled fork stability to maintain genome integrity. Cell Reports 34:4, pages 108669.
Crossref
Gaëlle Marenne, Audrey E. Hendricks, Aliki Perdikari, Rebecca Bounds, Felicity Payne, Julia M. Keogh, Christopher J. Lelliott, Elana Henning, Saad Pathan, Sofie Ashford, Elena G. Bochukova, Vanisha Mistry, Allan Daly, Caroline Hayward, Nicholas J. Wareham, Stephen O’Rahilly, Claudia Langenberg, Eleanor Wheeler, Eleftheria Zeggini, I. Sadaf Farooqi & Inês Barroso. (2020) Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription. Cell Metabolism 31:6, pages 1107-1119.e12.
Crossref
David de SemirVladimir BezrookoveMehdi NosratiKara R. ScanlonEric SingerJonathon Judkins, Christopher RiekenClayton WuJulia ShenChristina SchmudermayerAltaf A. DarJames R. MillerIIIIII, Charles CobbsGarret YountPierre-Yves DesprezRobert J. DebsNathan SalomonisSean McAllisterJames E. Cleaver, Liliana Soroceanu & Mohammed Kashani-Sabet. (2020) PHIP drives glioblastoma motility and invasion by regulating the focal adhesion complex. Proceedings of the National Academy of Sciences 117:16, pages 9064-9073.
Crossref
Oliver Bechter & Patrick Schöffski. (2020) Make your best BET: The emerging role of BET inhibitor treatment in malignant tumors. Pharmacology & Therapeutics 208, pages 107479.
Crossref
Huihui Zhu, Tao Wei, Yong Cai & Jingji Jin. (2020) Small Molecules Targeting the Specific Domains of Histone-Mark Readers in Cancer Therapy. Molecules 25:3, pages 578.
Crossref
Helen M. McRae, Samantha Eccles, Lachlan Whitehead, Warren S. Alexander, Jozef Gécz, Tim Thomas & Anne K. Voss. (2020) Downregulation of the GHRH/GH/IGF-1 axis in a mouse model of Börjeson-Forssman-Lehman Syndrome. Development.
Crossref
Kirsten E. Craddock, Volkan Okur, Ashley Wilson, Erica H. Gerkes, Keri Ramsey, Jennifer M. Heeley, Jane Juusola, Antonio Vitobello, Marie-Noelle Bonnet Dupeyron, Laurence Faivre & Wendy K. Chung. (2019) Clinical and genetic characterization of individuals with predicted deleterious PHIP variants . Molecular Case Studies 5:4, pages a004200.
Crossref
Mehrosh Pervaiz, Pankaj Mishra & Stefan Günther. 2019. Epigenetic Drug Discovery. Epigenetic Drug Discovery 347 381 .
Mohammed Kashani-Sabet, Vladimir Bezrookove & David de Semir. (2018) PHIPing along: Evolution of PHIP as a cancer biomarker and a target for therapy. Oncotarget 9:90, pages 36055-36056.
Crossref
Subhankar Biswas & C. Mallikarjuna Rao. (2018) Epigenetic tools (The Writers, The Readers and The Erasers) and their implications in cancer therapy. European Journal of Pharmacology 837, pages 8-24.
Crossref
Sang-Min Jang, Ya Zhang, Koichi Utani, Haiqing Fu, Christophe E. Redon, Anna B. Marks, Owen K. Smith, Catherine J. Redmond, Adrian M. Baris, Danielle A. Tulchinsky & Mirit I. Aladjem. (2018) The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin. Nature Communications 9:1.
Crossref
Sandra Jansen, Alexander Hoischen, Bradley P. Coe, Gemma L. Carvill, Hilde Van Esch, Daniëlle G. M. Bosch, Ulla A. Andersen, Carl Baker, Marijke Bauters, Raphael A. Bernier, Bregje W. van Bon, Hedi L. Claahsen-van der Grinten, Jozef Gecz, Christian Gilissen, Lucia Grillo, Anna Hackett, Tjitske Kleefstra, David Koolen, Malin Kvarnung, Martin J. Larsen, Carlo Marcelis, Fiona McKenzie, Marie-Lorraine Monin, Caroline Nava, Janneke H. Schuurs-Hoeijmakers, Rolph Pfundt, Marloes Steehouwer, Servi J. C. Stevens, Connie T. Stumpel, Fleur Vansenne, Mirella Vinci, Maartje van de Vorst, Petra de Vries, Kali Witherspoon, Joris A. Veltman, Han G. Brunner, Heather C. Mefford, Corrado Romano, Lisenka E. L. M. Vissers, Evan E. Eichler & Bert B. A. de Vries. (2017) A genotype-first approach identifies an intellectual disability-overweight syndrome caused by PHIP haploinsufficiency. European Journal of Human Genetics 26:1, pages 54-63.
Crossref
Takao Fujisawa & Panagis Filippakopoulos. (2017) Functions of bromodomain-containing proteins and their roles in homeostasis and cancer. Nature Reviews Molecular Cell Biology 18:4, pages 246-262.
Crossref
Emily Webster, Megan T. Cho, Nora Alexander, Sonal Desai, Sakkubai Naidu, Mir Reza Bekheirnia, Andrea Lewis, Kyle Retterer, Jane Juusola & Wendy K. Chung. (2016) De novo PHIP -predicted deleterious variants are associated with developmental delay, intellectual disability, obesity, and dysmorphic features . Molecular Case Studies 2:6, pages a001172.
Crossref
Ya Zhang, Liang Huang, Haiqing Fu, Owen K. Smith, Chii Mei Lin, Koichi Utani, Mishal Rao, William C. Reinhold, Christophe E. Redon, Michael Ryan, RyangGuk Kim, Yang You, Harlington Hanna, Yves Boisclair, Qiaoming Long & Mirit I. Aladjem. (2016) A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells. Nature Communications 7:1.
Crossref
Panagis Filippakopoulos & Stefan Knapp. 2016. Drug Discovery in Cancer Epigenetics. Drug Discovery in Cancer Epigenetics 239 271 .
Panagis Filippakopoulos & Stefan Knapp. (2012) The bromodomain interaction module. FEBS Letters 586:17, pages 2692-2704.
Crossref
Vijay Pratap Singh, B. Jyothi Lakshmi, Shalu Singh, Vanya Shah, Sandeep Goel, D. Partha Sarathi & Satish Kumar. (2012) Lack of Wdr13 Gene in Mice Leads to Enhanced Pancreatic Beta Cell Proliferation, Hyperinsulinemia and Mild Obesity. PLoS ONE 7:6, pages e38685.
Crossref
David De SemirMehdi NosratiVladimir BezrookoveAltaf A. DarScot FedermanGeraldine BienvenuSuraj VennaJavier RangelJoan Climent, Tanja M. Meyer Tamgüney, Suresh ThummalaSchuyler TongStanley P. L. Leong, Chris HaqqPaul Billings, James R. MillerIIIIIIRichard W. SagebielRobert DebsMohammed Kashani-Sabet. (2012) Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis. Proceedings of the National Academy of Sciences 109:18, pages 7067-7072.
Crossref
Panagis Filippakopoulos, Sarah Picaud, Maria Mangos, Tracy Keates, Jean-Philippe Lambert, Dalia Barsyte-Lovejoy, Ildiko Felletar, Rudolf Volkmer, Susanne Müller, Tony Pawson, Anne-Claude Gingras, Cheryl H. Arrowsmith & Stefan Knapp. (2012) Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family. Cell 149:1, pages 214-231.
Crossref
Shuai Li, Adam B. Francisco, Chunchun Han, Shrivatsav Pattabiraman, Monica R. Foote, Sarah L. Giesy, Chong Wang, John C. Schimenti, Yves R. Boisclair & Qiaoming Long. (2010) The full-length isoform of the mouse pleckstrin homology domain-interacting protein (PHIP) is required for postnatal growth. FEBS Letters 584:18, pages 4121-4127.
Crossref
Xing Wei, Lan Song, Lei Jiang, Guiliang Wang, Xinjing Luo, Bin Zhang & Xianzhong Xiao. (2010) Overexpression of MIP2, a novel WD-repeat protein, promotes proliferation of H9c2 cells. Biochemical and Biophysical Research Communications 393:4, pages 860-863.
Crossref
Sharon S. Zhang, Ergeng Hao, Jianxiu Yu, Wen Liu, Jing Wang, Fred Levine & Gen-Sheng Feng. (2009) Coordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic β-cells. Proceedings of the National Academy of Sciences 106:18, pages 7531-7536.
Crossref
Sigalit Boura‐Halfon & Yehiel Zick. 2009. Insulin and IGFs. Insulin and IGFs 313 349 .
Patricia W Lin, Tala R Nasr, Andrew J Berardinelli, Amrita Kumar & Andrew S Neish. (2008) The Probiotic Lactobacillus GG may Augment Intestinal Host Defense by Regulating Apoptosis and Promoting Cytoprotective Responses in the Developing Murine Gut. Pediatric Research 64:5, pages 511-516.
Crossref
Yue Shan, Shelley A. Cole, Karin Haack, Phillip E. Melton, Lyle G. Best, Christopher Bizon, Sayuko Kobes, Çiğdem Köroğlu, Leslie J. Baier, Robert L. Hanson, Serena Sanna, Yun Li & Nora Franceschini. (2021) Association of Protein Function-Altering Variants With Cardiometabolic Traits: The Strong Heart Study. SSRN Electronic Journal.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.