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Article

Cdk8 Regulates Stability of the Transcription Factor Phd1 To Control Pseudohyphal Differentiation of Saccharomyces cerevisiae

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Pages 664-674 | Received 30 Mar 2011, Accepted 08 Nov 2011, Published online: 20 Mar 2023

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Randall H. Morse. (2022) Function and dynamics of the Mediator complex: novel insights and new frontiers. Transcription 13:1-3, pages 39-52.
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Charli B. Fant & Dylan J. Taatjes. (2019) Regulatory functions of the Mediator kinases CDK8 and CDK19. Transcription 10:2, pages 76-90.
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Zachary C. Poss, Christopher C. Ebmeier & Dylan J. Taatjes. (2013) The Mediator complex and transcription regulation. Critical Reviews in Biochemistry and Molecular Biology 48:6, pages 575-608.
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Élie Lambert, Kavindu Puwakdandawa, Yi Fei Tao & François Robert. (2021) From structure to molecular condensates: emerging mechanisms for Mediator function. The FEBS Journal 290:2, pages 286-309.
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Virginia E. Glazier. (2022) EFG1, Everyone’s Favorite Gene in Candida albicans: A Comprehensive Literature Review. Frontiers in Cellular and Infection Microbiology 12.
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Jeffrey M. Hollomon, Zhongle Liu, Scott F. Rusin, Nicole P. Jenkins, Allia K. Smith, Katja Koeppen, Arminja N. Kettenbach, Lawrence C. Myers & Deborah A. Hogan. (2022) The Candida albicans Cdk8-dependent phosphoproteome reveals repression of hyphal growth through a Flo8-dependent pathway. PLOS Genetics 18:1, pages e1009622.
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Riley Horvath, Nicole Hawe, Cindy Lam, Konstantin Mestnikov, Mariam Eji-Lasisi, John Rohde & Ivan Sadowski. (2021) TORC1 signaling modulates Cdk8-dependent GAL gene expression in Saccharomyces cerevisiae . Genetics 219:4.
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Sara Osman, Eusra Mohammad, Michael Lidschreiber, Alexandra Stuetzer, Fanni Laura Bazsó, Kerstin C. Maier, Henning Urlaub & Patrick Cramer. (2021) The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II. Journal of Biological Chemistry 296, pages 100734.
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Maria J. Aristizabal, Kristy Dever, Gian Luca Negri, Mary Shen, Nicole Hawe, Joris J. Benschop, Frank C.P. Holstege, Nevan J. Krogan, Ivan Sadowski & Michael S. Kobor. (2019) Regulation of Skn7-dependent, oxidative stress-induced genes by the RNA polymerase II-CTD phosphatase, Fcp1, and Mediator kinase subunit, Cdk8, in yeast. Journal of Biological Chemistry 294:44, pages 16080-16094.
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Jing Xue, Elena Scotti & Markus Stoffel. (2019) CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells. Cell Reports 28:11, pages 2892-2904.e7.
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Yang Lu, Chang Su, Shatarupa Ray, Yuncong Yuan & Haoping Liu. (2019) CO 2 Signaling through the Ptc2-Ssn3 Axis Governs Sustained Hyphal Development of Candida albicans by Reducing Ume6 Phosphorylation and Degradation . mBio 10:1.
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Timothy Cholko, Wei Chen, Zhiye Tang & Chia-en A. Chang. (2018) A molecular dynamics investigation of CDK8/CycC and ligand binding: conformational flexibility and implication in drug discovery. Journal of Computer-Aided Molecular Design 32:6, pages 671-685.
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Georgios Pothoulakis & Tom Ellis. (2018) Synthetic gene regulation for independent external induction of the Saccharomyces cerevisiae pseudohyphal growth phenotype. Communications Biology 1:1.
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Lingyao Kong & Cheng Chang. (2017) Suppression of wheat TaCDK8/TaWIN1 interaction negatively affects germination of Blumeria graminis f.sp. tritici by interfering with very-long-chain aldehyde biosynthesis. Plant Molecular Biology 96:1-2, pages 165-178.
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Zhongle Liu & Lawrence C. Myers. (2017) Mediator Tail Module Is Required for Tac1-Activated CDR1 Expression and Azole Resistance in Candida albicans . Antimicrobial Agents and Chemotherapy 61:11.
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Célia Jeronimo & François Robert. (2017) The Mediator Complex: At the Nexus of RNA Polymerase II Transcription. Trends in Cell Biology 27:10, pages 765-783.
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Xiaobao Lin, Yanli Qi, Dongni Yan, Hui Liu, Xiulai Chen & Liming Liu. (2017) CgMED3 Changes Membrane Sterol Composition To Help Candida glabrata Tolerate Low-pH Stress . Applied and Environmental Microbiology 83:17.
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Michael J Law & Michael A Finger. (2017) The Saccharomyces cerevisiae Cdk8 Mediator Represses AQY1 Transcription by Inhibiting Set1p-Dependent Histone Methylation . G3 Genes|Genomes|Genetics 7:3, pages 1001-1010.
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Célia Jeronimo, Marie-France Langelier, Alain R. Bataille, John M. Pascal, B. Franklin Pugh & François Robert. (2016) Tail and Kinase Modules Differently Regulate Core Mediator Recruitment and Function In Vivo. Molecular Cell 64:3, pages 455-466.
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Zachary C. Poss, Christopher C. Ebmeier, Aaron T. Odell, Anupong Tangpeerachaikul, Thomas Lee, Henry E. Pelish, Matthew D. Shair, Robin D. Dowell, William M. Old & Dylan J. Taatjes. (2016) Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics. Cell Reports 15:2, pages 436-450.
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Adeline Humbert, Elodie Bovier, Carole H. Sellem & Annie Sainsard-Chanet. (2015) Deletion of the MED13 and CDK8 subunits of the Mediator improves the phenotype of a long-lived respiratory deficient mutant of Podospora anserina. Fungal Genetics and Biology 82, pages 228-237.
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S. D. Willger, Z. Liu, R. A. Olarte, M. E. Adamo, J. E. Stajich, L. C. Myers, A. N. Kettenbach & D. A. Hogan. (2015) Analysis of the Candida albicans Phosphoproteome. Eukaryotic Cell 14:5, pages 474-485.
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Michael J Law & Kerri Ciccaglione. (2015) Fine-Tuning of Histone H3 Lys4 Methylation During Pseudohyphal Differentiation by the CDK Submodule of RNA Polymerase II. Genetics 199:2, pages 435-453.
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Anja Wartenberg, Jörg Linde, Ronny Martin, Maria Schreiner, Fabian Horn, Ilse D. Jacobsen, Sabrina Jenull, Thomas Wolf, Karl Kuchler, Reinhard Guthke, Oliver Kurzai, Anja Forche, Christophe d'Enfert, Sascha Brunke & Bernhard Hube. (2014) Microevolution of Candida albicans in Macrophages Restores Filamentation in a Nonfilamentous Mutant. PLoS Genetics 10:12, pages e1004824.
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Allia K. Lindsay, Diana K. Morales, Zhongle Liu, Nora Grahl, Anda Zhang, Sven D. Willger, Lawrence C. Myers & Deborah A. Hogan. (2014) Analysis of Candida albicans Mutants Defective in the Cdk8 Module of Mediator Reveal Links between Metabolism and Biofilm Formation. PLoS Genetics 10:10, pages e1004567.
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Josipa Nemet, Branka Jelicic, Ivica Rubelj & Mary Sopta. (2014) The two faces of Cdk8, a positive/negative regulator of transcription. Biochimie 97, pages 22-27.
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Zsolt Szilagyi & Claes M. Gustafsson. (2013) Emerging roles of Cdk8 in cell cycle control. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1829:9, pages 916-920.
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Maria J. Aristizabal, Gian Luca Negri, Joris J. Benschop, Frank C. P. Holstege, Nevan J. Krogan & Michael S. Kobor. (2013) High-Throughput Genetic and Gene Expression Analysis of the RNAPII-CTD Reveals Unexpected Connections to SRB10/CDK8. PLoS Genetics 9:8, pages e1003758.
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I. Sadowski, B.-J. Breitkreutz, C. Stark, T.-C. Su, M. Dahabieh, S. Raithatha, W. Bernhard, R. Oughtred, K. Dolinski, K. Barreto & M. Tyers. (2013) The PhosphoGRID Saccharomyces cerevisiae protein phosphorylation site database: version 2.0 update. Database 2013:0, pages bat026-bat026.
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