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Research Article

Translational Regulation in Response to Changes in Amino Acid Availability in Neurospora crassa

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Pages 5235-5245 | Received 20 Jan 1995, Accepted 26 Jun 1995, Published online: 30 Mar 2023

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Read on this site (4)

Jiajie Wei, Cheng Wu & Matthew S. Sachs. (2012) The Arginine Attenuator Peptide Interferes with the Ribosome Peptidyl Transferase Center. Molecular and Cellular Biology 32:13, pages 2396-2406.
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Ke Zhan, Krishna M. Vattem, Bettina N. Bauer, Thomas E. Dever, Jane-Jane Chen & Ronald C. Wek. (2002) Phosphorylation of Eukaryotic Initiation Factor 2 by Heme-Regulated Inhibitor Kinase-Related Protein Kinases in Schizosaccharomyces pombe Is Important for Resistance to Environmental Stresses. Molecular and Cellular Biology 22:20, pages 7134-7146.
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Zhong Wang, Peng Fang & Matthew S. Sachs. (1998) The Evolutionarily Conserved Eukaryotic Arginine Attenuator Peptide Regulates the Movement of Ribosomes That Have Translated It. Molecular and Cellular Biology 18:12, pages 7528-7536.
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Zhong Wang & Matthew S. Sachs. (1997) Ribosome Stalling Is Responsible for Arginine-Specific Translational Attenuation in Neurospora crassa. Molecular and Cellular Biology 17:9, pages 4904-4913.
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Articles from other publishers (43)

Lunda Shen, Zhaoming Su, Kailu Yang, Cheng Wu, Thomas Becker, Deborah Bell-Pedersen, Junjie Zhang & Matthew S. Sachs. (2021) Structure of the translating Neurospora ribosome arrested by cycloheximide . Proceedings of the National Academy of Sciences 118:48.
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Thomas E. DeverIvaylo P. IvanovMatthew S. Sachs. (2020) Conserved Upstream Open Reading Frame Nascent Peptides That Control Translation. Annual Review of Genetics 54:1, pages 237-264.
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Xueliang Lyu, Qian Yang, Lin Li, Yunkun Dang, Zhipeng Zhou, She Chen & Yi Liu. (2020) Adaptation of codon usage to tRNA I34 modification controls translation kinetics and proteome landscape. PLOS Genetics 16:6, pages e1008836.
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Stanislava Gunišová, Vladislava Hronová, Mahabub Pasha Mohammad, Alan G Hinnebusch & Leoš Shivaya Valášek. (2017) Please do not recycle! Translation reinitiation in microbes and higher eukaryotes. FEMS Microbiology Reviews 42:2, pages 165-192.
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Shaohua Qi, Lingaonan He, Qin Zhang, Qing Dong, Yajun Wang, Qiuying Yang, Chaoguang Tian, Qun He & Ying Wang. (2018) Cross-pathway control gene CPC1/GCN4 coordinates with histone acetyltransferase GCN5 to regulate catalase-3 expression under oxidative stress in Neurospora crassa. Free Radical Biology and Medicine 117, pages 218-227.
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Ivaylo P. Ivanov, Jiajie Wei, Stephen Z. Caster, Kristina M. Smith, Audrey M. Michel, Ying Zhang, Andrew E. Firth, Michael Freitag, Jay C. Dunlap, Deborah Bell-Pedersen, John F. Atkins & Matthew S. Sachs. (2017) Translation Initiation from Conserved Non-AUG Codons Provides Additional Layers of Regulation and Coding Capacity. mBio 8:3.
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Ying Zhang & Matthew S Sachs. (2015) Control of mRNA Stability in Fungi by NMD, EJC and CBC Factors Through 3′UTR Introns. Genetics 200:4, pages 1133-1148.
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Martina M. Yordanova, Cheng Wu, Dmitry E. Andreev, Matthew S. Sachs & John F. Atkins. (2015) A Nascent Peptide Signal Responsive to Endogenous Levels of Polyamines Acts to Stimulate Regulatory Frameshifting on Antizyme mRNA. Journal of Biological Chemistry 290:29, pages 17863-17878.
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Dmitry E Andreev, Patrick BF O'Connor, Ciara Fahey, Elaine M Kenny, Ilya M Terenin, Sergey E Dmitriev, Paul Cormican, Derek W Morris, Ivan N Shatsky & Pavel V Baranov. (2015) Translation of 5′ leaders is pervasive in genes resistant to eIF2 repression. eLife 4.
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Lanelle R. Connolly, Kristina M. Smith & Michael Freitag. (2013) The Fusarium graminearum Histone H3 K27 Methyltransferase KMT6 Regulates Development and Expression of Secondary Metabolite Gene Clusters. PLoS Genetics 9:10, pages e1003916.
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Hong Loan Nguyen, Xi Yang & Curtis J. Omiecinski. (2013) Expression of a novel mRNA transcript for human microsomal epoxide hydrolase (EPHX1) is regulated by short open reading frames within its 5′-untranslated region. RNA 19:6, pages 752-766.
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Jiajie Wei, Ying Zhang, Ivaylo P. Ivanov & Matthew S. Sachs. (2013) The Stringency of Start Codon Selection in the Filamentous Fungus Neurospora crassa. Journal of Biological Chemistry 288:13, pages 9549-9562.
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XUJUN ZHU, SUNIL KUMAR THALOR, YOSHIHIRO TAKAHASHI, THOMAS BERBERICH & TOMONOBU KUSANO. (2012) An inhibitory effect of the sequence-conserved upstream open-reading frame on the translation of the main open-reading frame of HsfB1 transcripts in Arabidopsis . Plant, Cell & Environment 35:11, pages 2014-2030.
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Luis Rogelio Cruz-Vera, Matthew S Sachs, Catherine L Squires & Charles Yanofsky. (2011) Nascent polypeptide sequences that influence ribosome function. Current Opinion in Microbiology 14:2, pages 160-166.
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Christina C. Spevak, Ivaylo P. Ivanov & Matthew S. Sachs. (2010) Sequence Requirements for Ribosome Stalling by the Arginine Attenuator Peptide. Journal of Biological Chemistry 285:52, pages 40933-40942.
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Gregory O. Kothe, Maki Kitamura, Mitsuko Masutani, Eric U. Selker & Hirokazu Inoue. (2010) PARP is involved in replicative aging in Neurospora crassa. Fungal Genetics and Biology 47:4, pages 297-309.
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Heather M. Hood, Daniel E. Neafsey, James Galagan & Matthew S. Sachs. (2009) Evolutionary Roles of Upstream Open Reading Frames in Mediating Gene Regulation in Fungi. Annual Review of Microbiology 63:1, pages 385-409.
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Cheng Wu, Yun-Sik Kim, Kristina M Smith, Weixi Li, Heather M Hood, Chuck Staben, Eric U Selker, Matthew S Sachs & Mark L Farman. (2009) Characterization of Chromosome Ends in the Filamentous Fungus Neurospora crassa . Genetics 181:3, pages 1129-1145.
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Zachary A Lewis, Anthony L Shiver, Nicholas Stiffler, Michael R Miller, Eric A Johnson & Eric U Selker. (2007) High-Density Detection of Restriction-Site-Associated DNA Markers for Rapid Mapping of Mutated Loci in Neurospora. Genetics 177:2, pages 1163-1171.
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Heather M. Hood, Christina C. Spevak & Matthew S. Sachs. (2007) Evolutionary changes in the fungal carbamoyl-phosphate synthetase small subunit gene and its associated upstream open reading frame. Fungal Genetics and Biology 44:2, pages 93-104.
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Xiao-Ling Zhou, Wei Shen, Jian Zhuge & Zheng-Xiang Wang. (2006) Biochemical properties of a thermostable phytase from Neurospora crassa. FEMS Microbiology Letters 258:1, pages 61-66.
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Hildur V. Colot, Jennifer J. Loros & Jay C. Dunlap. (2005) Temperature-modulated Alternative Splicing and Promoter Use in the Circadian Clock Gene frequency . Molecular Biology of the Cell 16:12, pages 5563-5571.
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Anthony Gaba, Allan Jacobson & Matthew S. Sachs. (2005) Ribosome Occupancy of the Yeast CPA1 Upstream Open Reading Frame Termination Codon Modulates Nonsense-Mediated mRNA Decay. Molecular Cell 20:3, pages 449-460.
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Alan G. Hinnebusch. (2005) TRANSLATIONAL REGULATION OF GCN4 AND THE GENERAL AMINO ACID CONTROL OF YEAST . Annual Review of Microbiology 59:1, pages 407-450.
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Jeffrey G. Lawrence. (2003) Gene Organization: Selection, Selfishness, and Serendipity. Annual Review of Microbiology 57:1, pages 419-440.
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H. Diego Folco, Michael Freitag, Ana Ramón, Esteban D. Temporini, María E. Alvarez, Irene García, Claudio Scazzocchio, Eric U. Selker & Alberto L. Rosa. (2003) Histone H1 Is Required for Proper Regulation of Pyruvate Decarboxylase Gene Expression in Neurospora crassa . Eukaryotic Cell 2:2, pages 341-350.
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James E. Galagan, Sarah E. Calvo, Katherine A. Borkovich, Eric U. Selker, Nick D. Read, David Jaffe, William FitzHugh, Li-Jun Ma, Serge Smirnov, Seth Purcell, Bushra Rehman, Timothy Elkins, Reinhard Engels, Shunguang Wang, Cydney B. Nielsen, Jonathan Butler, Matthew Endrizzi, Dayong Qui, Peter Ianakiev, Deborah Bell-Pedersen, Mary Anne Nelson, Margaret Werner-Washburne, Claude P. Selitrennikoff, John A. Kinsey, Edward L. Braun, Alex Zelter, Ulrich Schulte, Gregory O. Kothe, Gregory Jedd, Werner Mewes, Chuck Staben, Edward Marcotte, David Greenberg, Alice Roy, Karen Foley, Jerome Naylor, Nicole Stange-Thomann, Robert Barrett, Sante Gnerre, Michael Kamal, Manolis Kamvysselis, Evan Mauceli, Cord Bielke, Stephen Rudd, Dmitrij Frishman, Svetlana Krystofova, Carolyn Rasmussen, Robert L. Metzenberg, David D. Perkins, Scott Kroken, Carlo Cogoni, Giuseppe Macino, David Catcheside, Weixi Li, Robert J. Pratt, Stephen A. Osmani, Colin P. C. DeSouza, Louise Glass, Marc J. Orbach, J. Andrew Berglund, Rodger Voelker, Oded Yarden, Michael Plamann, Stephan Seiler, Jay Dunlap, Alan Radford, Rodolfo Aramayo, Donald O. Natvig, Lisa A. Alex, Gertrud Mannhaupt, Daniel J. Ebbole, Michael Freitag, Ian Paulsen, Matthew S. Sachs, Eric S. Lander, Chad Nusbaum & Bruce Birren. (2003) The genome sequence of the filamentous fungus Neurospora crassa. Nature 422:6934, pages 859-868.
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Peng Fang, Cheng Wu & Matthew S Sachs. (2002) Neurospora crassa supersuppressor mutants are amber codon-specific. Fungal Genetics and Biology 36:3, pages 167-175.
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Jeffrey G. Lawrence. (2002) Shared Strategies in Gene Organization among Prokaryotes and Eukaryotes. Cell 110:4, pages 407-413.
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Michael Freitag, Rebecca L. Williams, Gregory O. Kothe & Eric U. Selker. (2002) A cytosine methyltransferase homologue is essential for repeat-induced point mutation in Neurospora crassa . Proceedings of the National Academy of Sciences 99:13, pages 8802-8807.
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Thomas E. Dever. (2002) Gene-Specific Regulation by General Translation Factors. Cell 108:4, pages 545-556.
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Bernd Hoffmann, Oliver Valerius, Meike Andermann & Gerhard H. Braus. (2001) Transcriptional Autoregulation and Inhibition of mRNA Translation of Amino Acid Regulator Gene cpcA of Filamentous Fungus Aspergillus nidulans . Molecular Biology of the Cell 12:9, pages 2846-2857.
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Peng Fang, Zhong Wang & Matthew S. Sachs. (2000) Evolutionarily Conserved Features of the Arginine Attenuator Peptide Provide the Necessary Requirements for Its Function in Translational Regulation. Journal of Biological Chemistry 275:35, pages 26710-26719.
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Vivian P.W. Miao, Michael Freitag & Eric U. Selker. (2000) Short TpA-rich segments of the ζ-η region induce DNA methylation in Neurospora crassa 1 1Edited by K. Yamamoto. Journal of Molecular Biology 300:2, pages 249-273.
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Zhong Wang, Anthony Gaba & Matthew S. Sachs. (1999) A Highly Conserved Mechanism of Regulated Ribosome Stalling Mediated by Fungal Arginine Attenuator Peptides That Appears Independent of the Charging Status of Arginyl-tRNAs. Journal of Biological Chemistry 274:53, pages 37565-37574.
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Evelyn Sattlegger, Alan G. Hinnebusch & Ilse B. Barthelmess. (1998) cpc-3, the Neurospora crassa Homologue of Yeast GCN2, Encodes a Polypeptide with Juxtaposed eIF2α Kinase and Histidyl-tRNA Synthetase-related Domains Required for General Amino Acid Control. Journal of Biological Chemistry 273:32, pages 20404-20416.
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M. S. Sachs, E. U. Selker, B. Lin, C. J. Roberts, Z. Luo, D. Vaught-Alexander & B. S. Margolin. (1997) Expression of herpes virus thymidine kinase in Neurospora crassa. Nucleic Acids Research 25:12, pages 2389-2395.
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Wei-Chiang Shen & Daniel J. Ebbole. (1997) Cross-Pathway and Pathway-Specific Control of Amino Acid Biosynthesis inMagnaporthe grisea. Fungal Genetics and Biology 21:1, pages 40-49.
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Zhong Wang & Matthew S. Sachs. (1997) Arginine-specific Regulation Mediated by the Neurospora crassa arg-2 Upstream Open Reading Frame in a Homologous, Cell-free in Vitro Translation System. Journal of Biological Chemistry 272:1, pages 255-261.
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P S Lovett & E J Rogers. (1996) Ribosome regulation by the nascent peptide. Microbiological Reviews 60:2, pages 366-385.
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Z LuoM S Sachs. (1996) Role of an upstream open reading frame in mediating arginine-specific translational control in Neurospora crassa. Journal of Bacteriology 178:8, pages 2172-2177.
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