Advanced search
Publication Cover
Molecular and Cellular Biology Volume 15, 1995 - Issue 12
Submit an article Journal homepage
2
Views
49
CrossRef citations to date
0
Altmetric
Research Article

v-Abl Activates c-myc Transcription through the E2F Site

Kwok-Kin Wong1 Integrated Program in Cellular, Molecular and Biophysical Studies, Columbia University, New York, New York10032
,
Xiaoming Zou2 Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York10032
,
Kevin T. Merrell1 Integrated Program in Cellular, Molecular and Biophysical Studies, Columbia University, New York, New York10032
,
Amanda J. Patel3 Department of Biochemistry and Cell Biology, SUNY at Stony Brook, Stony Brook, New York11794
,
Kenneth B. Marcu3 Department of Biochemistry and Cell Biology, SUNY at Stony Brook, Stony Brook, New York11794
,
Srikumar Chellappan4 Columbia University College of Physicians and Surgeons, and Department of Pathology, Columbia University, New York, New York10032
&
Kathryn Calame1 Integrated Program in Cellular, Molecular and Biophysical Studies, Columbia University, New York, New York10032;2 Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York10032;5 Department of Microbiology, Columbia University, New York, New York10032
 show all
Pages 6535-6544 | Received 07 Jun 1995, Accepted 06 Sep 1995, Published online: 30 Mar 2023

Citations (49)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (7)

Amy S. Weinmann, Stephanie M. Bartley, Theresa Zhang, Michael Q. Zhang & Peggy J. Farnham. (2001) Use of Chromatin Immunoprecipitation To Clone Novel E2F Target Promoters. Molecular and Cellular Biology 21:20, pages 6820-6832.
Read now
Danilo Perrotti, Angela Iervolino, Vincenzo Cesi, Maria Cirinná, Silvia Lombardini, Emanuela Grassilli, Silvia Bonatti, Pier Paolo Claudio & Bruno Calabretta. (2000) BCR-ABL Prevents c-Jun-Mediated and Proteasome-Dependent FUS (TLS) Proteolysis through a Protein Kinase CβII-Dependent Pathway. Molecular and Cellular Biology 20:16, pages 6159-6169.
Read now
Xiaoming Zou, Feng Cong, Margaret Coutts, Giorgio Cattoretti, Stephen P. Goff & Kathryn Calame. (2000) p53 Deficiency Increases Transformation by v-Abl and Rescues the Ability of a C-Terminally Truncated v-Abl Mutant To Induce Pre-B Lymphoma In Vivo. Molecular and Cellular Biology 20:2, pages 628-633.
Read now
Indira Unnikrishnan, Arash Radfar, Jenia Jenab-Wolcott & Naomi Rosenberg. (1999) p53 Mediates Apoptotic Crisis in Primary Abelson Virus-Transformed Pre-B Cells. Molecular and Cellular Biology 19:7, pages 4825-4831.
Read now
Sheng Wang, Richik N. Ghosh & Srikumar P. Chellappan. (1998) Raf-1 Physically Interacts with Rb and Regulates Its Function: a Link between Mitogenic Signaling and Cell Cycle Regulation. Molecular and Cellular Biology 18:12, pages 7487-7498.
Read now
Eva M. Weissinger, Günther Eissner, Christine Grammer, Susanne Fackler, Burkhard Haefner, Luke S. Yoon, Kimberly S. Lu, Alex Bazarov, John M. Sedivy, Harald Mischak & Walter Kolch. (1997) Inhibition of the Raf-1 Kinase by Cyclic AMP Agonists Causes Apoptosis of v-abl-Transformed Cells. Molecular and Cellular Biology 17:6, pages 3229-3241.
Read now
Linda M. Facchini, Shaojun Chen, Wilson W. Marhin, Justin N. Lear & Linda Z. Penn. (1997) The Myc Negative Autoregulation Mechanism Requires Myc-Max Association and Involves the c-myc P2 Minimal Promoter. Molecular and Cellular Biology 17:1, pages 100-114.
Read now

Articles from other publishers (42)

Jacob P. Hoj, Benjamin Mayro & Ann Marie Pendergast. (2020) The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis. Proceedings of the National Academy of Sciences 117:52, pages 33486-33495.
Crossref
Christine Victoria Ichim. (2014) Kinase-Independent Mechanisms of Resistance of Leukemia Stem Cells to Tyrosine Kinase Inhibitors. Stem Cells Translational Medicine 3:4, pages 405-415.
Crossref
G. Vignir Helgason, Jim O'Prey & Kevin M. Ryan. (2010) Oncogene-Induced Sensitization to Chemotherapy-Induced Death Requires Induction as well as Deregulation of E2F1. Cancer Research 70:10, pages 4074-4080.
Crossref
Rebekah Stackpole Zimmerman & Naomi Rosenberg. (2008) Changes in p19 Arf Localization Accompany Apoptotic Crisis during Pre-B-Cell Transformation by Abelson Murine Leukemia Virus . Journal of Virology 82:17, pages 8383-8391.
Crossref
Cuixia Chen, Xin Shang, Lingling Cui, Ting Xu, Jixian Luo, Xueqing Ba & Xianlu Zeng. (2008) L-selectin ligation-induced CSF-1 gene transcription is regulated by AP-1 in a c-Abl kinase-dependent manner. Human Immunology 69:8, pages 501-509.
Crossref
Inken Wierstra & Jürgen Alves. 2008. 113 333 .
Inna Serganova, Phillipp Mayer-Kukuck, Ruimin Huang & Ronald Blasberg. 2008. Molecular Imaging II. Molecular Imaging II 167 223 .
Mihalis Verykokakis, Chara Papadaki, Elena Vorgia, Lionel Le Gallic & George Mavrothalassitis. (2007) The RAS-dependent ERF Control of Cell Proliferation and Differentiation Is Mediated by c-Myc Repression. Journal of Biological Chemistry 282:41, pages 30285-30294.
Crossref
Carine Kolly, Antony Zakher, Christian Strauss, Maja M. Suter & Eliane J. Müller. (2007) Keratinocyte transcriptional regulation of the human c-Myc promoter occurs via a novel Lef/Tcf binding element distinct from neoplastic cells. FEBS Letters 581:10, pages 1969-1976.
Crossref
Inna Serganova & Ronald G. Blasberg. (2006) Multi-Modality Molecular Imaging of Tumors. Hematology/Oncology Clinics of North America 20:6, pages 1215-1248.
Crossref
Asit K. Nandi & Aaron P. Rapoport. (2006) Expression of PDZ-binding kinase (PBK) is regulated by cell cycle-specific transcription factors E2F and CREB/ATF. Leukemia Research 30:4, pages 437-447.
Crossref
Danilo Perrotti & Bruno Calabretta. (2004) Translational regulation by the p210 BCR/ABL oncoprotein. Oncogene 23:18, pages 3222-3229.
Crossref
Carlo Iavarone, Annunziata Catania, Maria Julia Marinissen, Roberta Visconti, Mario Acunzo, Carolina Tarantino, M. Stella Carlomagno, Carmelo B. Bruni, J. Silvio Gutkind & Mario Chiariello. (2003) The Platelet-derived Growth Factor Controls c-myc Expression through a JNK- and AP-1-dependent Signaling Pathway. Journal of Biological Chemistry 278:50, pages 50024-50030.
Crossref
Joan-Marc Servitja, Maria Julia Marinissen, Akrit Sodhi, Xosé R. Bustelo & J.Silvio Gutkind. (2003) Rac1 Function Is Required for Src-induced Transformation. Journal of Biological Chemistry 278:36, pages 34339-34346.
Crossref
Verena Strieder & Werner Lutz. (2003) E2F Proteins Regulate MYCN Expression in Neuroblastomas. Journal of Biological Chemistry 278:5, pages 2983-2989.
Crossref
Scott K Shore, Ramana V Tantravahi & E Premkumar Reddy. (2002) Transforming pathways activated by the v-Abl tyrosine kinase. Oncogene 21:56, pages 8568-8576.
Crossref
V. Strieder & W. Lutz. (2002) Regulation of N-myc expression in development and disease. Cancer Letters 180:2, pages 107-119.
Crossref
Ken Yagi, Masao Furuhashi, Hiromasa Aoki, Daisuke Goto, Hiroyuki Kuwano, Kazuo Sugamura, Kohei Miyazono & Mitsuyasu Kato. (2002) c-myc Is a Downstream Target of the Smad Pathway. Journal of Biological Chemistry 277:1, pages 854-861.
Crossref
Danilo Perrotti, Vincenzo Cesi, Rossana Trotta, Clara Guerzoni, Giorgia Santilli, Kenneth Campbell, Angela Iervolino, Fabrizio Condorelli, Carlo Gambacorti-Passerini, Michael A. Caligiuri & Bruno Calabretta. (2001) BCR-ABL suppresses C/EBPα expression through inhibitory action of hnRNP E2. Nature Genetics 30:1, pages 48-58.
Crossref
Steven E. Lang, Steven B. McMahon, Michael D. Cole & Patrick Hearing. (2001) E2F Transcriptional Activation Requires TRRAP and GCN5 Cofactors. Journal of Biological Chemistry 276:35, pages 32627-32634.
Crossref
Mario Chiariello, Maria Julia Marinissen & J. Silvio Gutkind. (2001) Regulation of c-myc expression by PDGF through Rho GTPases. Nature Cell Biology 3:6, pages 580-586.
Crossref
Margaret Coutts, Xiaoming Zou & Kathryn Calame. (2000) v-Abl utilizes multiple mechanisms to drive G1/S progression in fibroblasts. Oncogene 19:6, pages 801-809.
Crossref
Chilakamarti V. Ramana, Nicholas Grammatikakis, Mikhail Chernov, Hannah Nguyen, Kee Chuan Goh, Bryan R.G. Williams & George R. Stark. (2000) Regulation of c-myc expression by IFN-γ through Stat1-dependent and -independent pathways. The EMBO Journal 19:2, pages 263-272.
Crossref
Feng Cong, Xiaoming Zou, Karen Hinrichs, Kathryn Calame & Stephen P Goff. (2000) Inhibition of v-Abl transformation by p53 and p19ARF. Oncogene 18:54, pages 7731-7739.
Crossref
Marc W. Izzo, Gordon D. Strachan, Matthew C. Stubbs & David J. Hall. (1999) Transcriptional Repression from the c-myc P2 Promoter by the Zinc Finger Protein ZF87/MAZ. Journal of Biological Chemistry 274:27, pages 19498-19506.
Crossref
Tung O. ChanSusan E. RittenhousePhilip N. Tsichlis. (1999) AKT/PKB and Other D3 Phosphoinositide-Regulated Kinases: Kinase Activation by Phosphoinositide-Dependent Phosphorylation. Annual Review of Biochemistry 68:1, pages 965-1014.
Crossref
A Picon, X Bertagna & Y de Keyzer. (1999) Analysis of the human proopiomelanocortin gene promoter in a small cell lung carcinoma cell line reveals an unusual role for E2F transcription factors. Oncogene 18:16, pages 2627-2633.
Crossref
Nobuo Kiuchi, Koichi Nakajima, Makoto Ichiba, Toshiyuki Fukada, Masahiro Narimatsu, Katsunori Mizuno, Masahiko Hibi & Toshio Hirano. (1999) STAT3 Is Required for the gp130-mediated Full Activation of the c- myc Gene . The Journal of Experimental Medicine 189:1, pages 63-73.
Crossref
Arash Radfar, Indira Unnikrishnan, Han-Woong Lee, Ronald A. DePinho & Naomi Rosenberg. (1998) p19 Arf induces p53-dependent apoptosis during Abelson virus-mediated pre-B cell transformation . Proceedings of the National Academy of Sciences 95:22, pages 13194-13199.
Crossref
Catherine M. Verfaillie. (1998) BIOLOGY OF CHRONIC MYELOGENOUS LEUKEMIA. Hematology/Oncology Clinics of North America 12:1, pages 1-29.
Crossref
M. E. Ewen. 1998. Cell Cycle Control. Cell Cycle Control 149 179 .
James W. Wilson, Catherine Booth & Christopher S. PottenUsha Kasid & Simeng Suy. 1999. Apoptosis Genes. Apoptosis Genes 85 117 .
Mohammad Azam, Carolyn Lee, Inga Strehlow & Christian Schindler. (1997) Functionally Distinct Isoforms of STAT5 Are Generated by Protein Processing. Immunity 6:6, pages 691-701.
Crossref
Maria C. Birchenall-Roberts, Young Do Yoo, Daniel C. BertoletteIIIIII, Kwan-Hee Lee, Jennifer M. Turley, Ok-Sun Bang, Francis W. Ruscetti & Seong-Jin Kim. (1997) The p120-v-Abl Protein Interacts with E2F-1 and Regulates E2F-1 Transcriptional Activity. Journal of Biological Chemistry 272:14, pages 8905-8911.
Crossref
Tim Bui, Chiaoyun Kuo, Peter Rotwein & Daniel S. Straus. (1997) Prostaglandin A2 Specifically Represses Insulin-Like Growth Factor-I Gene Expression in C6 Rat Glioma Cells*. Endocrinology 138:3, pages 985-993.
Crossref
X Zou, S Rudchenko, K Wong & K Calame. (1997) Induction of c-myc transcription by the v-Abl tyrosine kinase requires Ras, Raf1, and cyclin-dependent kinases.. Genes & Development 11:5, pages 654-662.
Crossref
Robin Hesketh. 1997. The Oncogene & Tumour Suppressor Gene Factsbook. The Oncogene & Tumour Suppressor Gene Factsbook 287 301 .
Robin Hesketh. 1997. The Oncogene & Tumour Suppressor Gene Factsbook. The Oncogene & Tumour Suppressor Gene Factsbook 95 101 .
K. B. Marcu, A. J. Patel & Y. Yang. 1997. C-Myc in B-Cell Neoplasia. C-Myc in B-Cell Neoplasia 47 56 .
M. Potter & K. B. Marcu. 1997. C-Myc in B-Cell Neoplasia. C-Myc in B-Cell Neoplasia 1 17 .
Claude Sardet, Laurent LeCam, Eric Fabbrizio & Marc Vidal. 1997. Oncogenes as Transcriptional Regulators. Oncogenes as Transcriptional Regulators 1 62 .
Jean-Marc Lemaitre, Robin S. Buckle & Marcel Méchali. 1996. 95 144 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.