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Molecular and Cellular Biology Volume 15, 1995 - Issue 2
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Research Article

A Ternary Complex Factor-Dependent Mechanism Mediates Induction of egr-1 through Selective Serum Response Elements following Antigen Receptor Cross-Linking in B Lymphocytes

Steven B. McMahonDepartment of Pathology and Laboratory Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania19104
&
John G. MonroeDepartment of Pathology and Laboratory Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania19104
Pages 1086-1093 | Received 13 Jun 1994, Accepted 17 Nov 1994, Published online: 30 Mar 2023

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Kasumi Murai & Richard Treisman. (2002) Interaction of Serum Response Factor (SRF) with the Elk-1 B Box Inhibits RhoA-Actin Signaling to SRF and Potentiates Transcriptional Activation by Elk-1. Molecular and Cellular Biology 22:20, pages 7083-7092.
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Jean-Luc Schwachtgen, Callum J. Campbell & Martin Braddock. (2000) Full Promoter Sequence of Human Early Growth Response Factor-1 (Egr-1): Demonstration of a Fifth Functional Serum Response Element. DNA Sequence 10:6, pages 429-432.
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Christel Aperlo, Philippe Pognonec, E. Richard Stanley & Kim E. Boulukos. (1996) Constitutive c-ets2 Expression in M1D+ Myeloblast Leukemic Cells Induces Their Differentiation to Macrophages. Molecular and Cellular Biology 16:12, pages 6851-6858.
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Chang-Yan Chen, Lora W. Forman & Douglas V. Faller. (1996) Calcium-Dependent Immediate-Early Gene Induction in Lymphocytes Is Negatively Regulated by p21Ha-. Molecular and Cellular Biology 16:11, pages 6582-6592.
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Ching Yi Chen & Robert J. Schwartz. (1996) Recruitment of the Tinman Homolog Nkx-2.5 by Serum Response Factor Activates Cardiac α-Actin Gene Transcription. Molecular and Cellular Biology 16:11, pages 6372-6384.
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Hendrik Gille, Monika Kortenjann, Thomas Strahl & Peter E. Shaw. (1996) Phosphorylation-Dependent Formation of a Quaternary Complex at the c-fos SRE. Molecular and Cellular Biology 16:3, pages 1094-1102.
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Articles from other publishers (51)

Emmanuelle Havis & Delphine Duprez. (2020) EGR1 Transcription Factor is a Multifaceted Regulator of Matrix Production in Tendons and Other Connective Tissues. International Journal of Molecular Sciences 21:5, pages 1664.
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Seung-Min Lee, Sun Bok Lee, Ron Prywes & Christopher D. Vulpe. (2015) Iron deficiency upregulates Egr1 expression. Genes & Nutrition 10:4.
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Alina Gajewska, Andrzej P Herman, Ewa Wolińska-Witort, Kazimierz Kochman & Lech Zwierzchowski. (2014) In vivo oestrogenic modulation of Egr1 and Pitx1 gene expression in female rat pituitary gland. Journal of Molecular Endocrinology 53:3, pages 355-366.
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Marcus J. Tindall & Angela Clerk. (2014) Modelling Negative Feedback Networks for Activating Transcription Factor 3 Predicts a Dominant Role for miRNAs in Immediate Early Gene Regulation. PLoS Computational Biology 10:5, pages e1003597.
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H. KOMURA, M. UCHIBA, Y. MIZUOCHI, M. ARAI, N. HARADA, H. KATSUYA & K. OKAJIMA. (2008) Antithrombin inhibits lipopolysaccharide-induced tumor necrosis factor-α production by monocytes in vitro through inhibition of Egr-1 expression. Journal of Thrombosis and Haemostasis 6:3, pages 499-507.
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Anne Fleige, Siegfried Alberti, Lothar Groöbe, Ursula Frischmann, Robert Geffers, Werner Muöller, Alfred Nordheim & Angela Schippers. (2007) Serum Response Factor Contributes Selectively to Lymphocyte Development. Journal of Biological Chemistry 282:33, pages 24320-24328.
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Jiyuan Ke, Murali Gururajan, Anupam Kumar, Alan Simmons, Lilia Turcios, Ralph L. Chelvarajan, David M. Cohen, David L. Wiest, John G. Monroe & Subbarao Bondada. (2006) The Role of MAPKs in B Cell Receptor-induced Down-regulation of Egr-1 in Immature B Lymphoma Cells. Journal of Biological Chemistry 281:52, pages 39806-39818.
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Yao Chang, Heng-Huan Lee, Yu-Te Chen, Jean Lu, Shih-Yi Wu, Chaio-Wei Chen, Kenzo Takada & Ching-Hwa Tsai. (2006) Induction of the Early Growth Response 1 Gene by Epstein-Barr Virus Lytic Transactivator Zta. Journal of Virology 80:15, pages 7748-7755.
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A Chen, J Xu & A C Johnson. (2005) Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1. Oncogene 25:2, pages 278-287.
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Inge Bauer, Mathias Hohl, Alia Al-Sarraj, Charles Vinson & Gerald Thiel. (2005) Transcriptional activation of the Egr-1 gene mediated by tetradecanoylphorbol acetate and extracellular signal-regulated protein kinase. Archives of Biochemistry and Biophysics 438:1, pages 36-52.
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L. M. Corcoran. 2005. Molecular Analysis of B Lymphocyte Development and Activation. Molecular Analysis of B Lymphocyte Development and Activation 105 146 .
Ewelina Knapska & Leszek Kaczmarek. (2004) A gene for neuronal plasticity in the mammalian brain: Zif268/Egr-1/NGFI-A/Krox-24/TIS8/ZENK?. Progress in Neurobiology 74:4, pages 183-211.
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Levon M Khachigian. (2004) DNAzymes as molecular agents that manipulate Egr-1 gene expression. Biochemical Pharmacology 68:6, pages 1023-1025.
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Patrick S Costello, Robert H Nicolas, Yasuyuki Watanabe, Ian Rosewell & Richard Treisman. (2004) Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection. Nature Immunology 5:3, pages 289-298.
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András Schaefer, Ferenc Kósa, Thomas Bittorf, Mária Magócsi, Anette Rosche, Yoandra Ramirez-Chávez, Stefan Marotzki & Hans Marquardt. (2004) Opposite effects of inhibitors of mitogen-activated protein kinase pathways on the egr-1 and β-globin expression in erythropoietin-responsive murine erythroleukemia cells. Cellular Signalling 16:2, pages 223-234.
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Peter E. Shaw & Janice Saxton. (2003) Ternary complex factors: prime nuclear targets for mitogen-activated protein kinases. The International Journal of Biochemistry & Cell Biology 35:8, pages 1210-1226.
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Rukhsana N. HasanSharbani PhukanShuko Harada. (2003) Differential Regulation of Early Growth Response Gene-1 Expression by Insulin and Glucose in Vascular Endothelial Cells. Arteriosclerosis, Thrombosis, and Vascular Biology 23:6, pages 988-993.
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Ariel Quiñones, Karl U Dobberstein & Nikolai G Rainov. (2003) The egr-1 gene is induced by DNA-damaging agents and non-genotoxic drugs in both normal and neoplastic human cells. Life Sciences 72:26, pages 2975-2992.
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Magali Bébien, Sara Salinas, Carine Becamel, Véronique Richard, Laetitia Linares & Robert A Hipskind. (2003) Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF. Oncogene 22:12, pages 1836-1847.
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Patricia Mora‐Garcia, Jerry Cheng, Heather N. Crans‐Vargas, Athena Countouriotis, Deepa Shankar & Kathleen M. Sakamoto. (2008) Transcriptional Regulators and Myelopoiesis: The Role of Serum Response Factor and CREB as Targets of Cytokine Signaling. STEM CELLS 21:2, pages 123-130.
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José Alberola-Ila & Gabriela Hernández-Hoyos. (2003) The Ras/MAPK cascade and the control of positive selection. Immunological Reviews 191:1, pages 79-96.
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Hongkang Xi & Gilbert J. Kersh. (2003) Induction of the Early Growth Response Gene 1 Promoter by TCR Agonists and Partial Agonists: Ligand Potency Is Related to Sustained Phosphorylation of Extracellular Signal-Related Kinase Substrates. The Journal of Immunology 170:1, pages 315-324.
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Jennitte L. StevensGreg T. CantinGang WangAndrej ShevchenkoAnna ShevchenkoArnold J. Berk. (2002) Transcription Control by E1A and MAP Kinase Pathway via Sur2 Mediator Subunit. Science 296:5568, pages 755-758.
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David A. Tice, Irina Soloviev & Paul Polakis. (2002) Activation of the Wnt Pathway Interferes with Serum Response Element-driven Transcription of Immediate Early Genes. Journal of Biological Chemistry 277:8, pages 6118-6123.
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Ernesto Bernal-Mizrachi, Wu Wen, Shanthi Srinivasan, Alison Klenk, David Cohen & M. Alan Permutt. (2001) Activation of Elk-1, an Ets transcription factor, by glucose and EGF treatment of insulinoma cells. American Journal of Physiology-Endocrinology and Metabolism 281:6, pages E1286-E1299.
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Laurent Guillemot, Arlette Levy, Michel Raymondjean & Bernard Rothhut. (2001) Angiotensin II-induced Transcriptional Activation of the Cyclin D1 Gene Is Mediated by Egr-1 in CHO-AT1A Cells. Journal of Biological Chemistry 276:42, pages 39394-39403.
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Robert Benezra. (2001) The Id proteins: targets for inhibiting tumor cells and their blood supply. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1551:2, pages F39-F47.
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