Citations (142)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (11)
Pallavi Mohanty & Sonika Bhatnagar. (2017) Structural basis of focal adhesion targeting domain-mediated signaling in cardiac hypertrophy. Journal of Receptors and Signal Transduction 37:1, pages 38-50.
Read now
Read now
Myeong Gu Yeo, Michael A. Partridge, Ellen J. Ezratty, Qiong Shen, Gregg G. Gundersen & Eugene E. Marcantonio. (2006) Src SH2 Arginine 175 Is Required for Cell Motility: Specific Focal Adhesion Kinase Targeting and Focal Adhesion Assembly Function. Molecular and Cellular Biology 26:12, pages 4399-4409.
Read now
Read now
M. A. Westhoff, B. Serrels, V. J. Fincham, M. C. Frame & N. O. Carragher. (2004) Src-Mediated Phosphorylation of Focal Adhesion Kinase Couples Actin and Adhesion Dynamics to Survival Signaling. Molecular and Cellular Biology 24:18, pages 8113-8133.
Read now
Read now
Madeleine Toutant, Alicia Costa, Jeanne-Marie Studler, Gress Kadaré, Michèle Carnaud & Jean-Antoine Girault. (2002) Alternative Splicing Controls the Mechanisms of FAK Autophosphorylation. Molecular and Cellular Biology 22:22, pages 7731-7743.
Read now
Read now
Leslie A. Cary, Richard A. Klinghoffer, Christoph Sachsenmaier & Jonathan A. Cooper. (2002) Src Catalytic but Not Scaffolding Function Is Needed for Integrin-Regulated Tyrosine Phosphorylation, Cell Migration, and Cell Spreading. Molecular and Cellular Biology 22:8, pages 2427-2440.
Read now
Read now
Marie-Claude Gingras, Claudia Champagne, Mélanie Roy & Josée N. Lavoie. (2002) Cytoplasmic Death Signal Triggered by Src-Mediated Phosphorylation of the Adenovirus E4orf4 Protein. Molecular and Cellular Biology 22:1, pages 41-56.
Read now
Read now
Valerie J. Fincham, Valerie G. Brunton & Margaret C. Frame. (2000) The SH3 Domain Directs Acto-Myosin-Dependent Targeting of v-Src to Focal Adhesions via Phosphatidylinositol 3-Kinase. Molecular and Cellular Biology 20:17, pages 6518-6536.
Read now
Read now
Günter Müller, Susanne Wied & Wendelin Frick. (2000) Cross Talk of pp125FAK and pp59Lyn Non-Receptor Tyrosine Kinases to Insulin-Mimetic Signaling in Adipocytes. Molecular and Cellular Biology 20:13, pages 4708-4723.
Read now
Read now
Barbara Valentinis, Andrea Morrione, Stephen J. Taylor & Renato Baserga. (1997) Insulin-Like Growth Factor I Receptor Signaling in Transformation by src Oncogenes. Molecular and Cellular Biology 17:7, pages 3744-3754.
Read now
Read now
David D. Schlaepfer & Tony Hunter. (1996) Evidence for In Vivo Phosphorylation of the Grb2 SH2-Domain Binding Site on Focal Adhesion Kinase by Src-Family Protein-Tyrosine Kinases. Molecular and Cellular Biology 16:10, pages 5623-5633.
Read now
Read now
Kristiina Vuori, Hisamaru Hirai, Shinichi Aizawa & Erkki Ruoslahti. (1996) Induction of p130 Signaling Complex Formation upon Integrin-Mediated Cell Adhesion: a Role for Src Family Kinases. Molecular and Cellular Biology 16:6, pages 2606-2613.
Read now
Read now
Articles from other publishers (131)
Jason A. Estep, Lu O. Sun & Martin M. Riccomagno. (2023) A luciferase fragment complementation assay to detect focal adhesion kinase (FAK) signaling events. Heliyon 9:4, pages e15282.
Crossref
Crossref
Valentina B. Ignjatović, Jelena R. Janković Miljuš, Jelena V. Rončević, Svetislav B. Tatić, Tijana M. Išić Denčić, Ilona Đ. Đorić & Sonja A. Šelemetjev. (2021) Focal adhesion kinase splicing and protein activation in papillary thyroid carcinoma progression. Histochemistry and Cell Biology 157:2, pages 183-194.
Crossref
Crossref
Jin Zheng, Lun Suo, Yuxiao Zhou, Liling Jia, Jingwei Li, Yanping Kuang, Donghong Cui, Xuehong Zhang & Qiang Wu. (2021) Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner. Journal of Molecular Cell Biology 13:11, pages 808-821.
Crossref
Crossref
Lihong Zhang, Xiaozhen Zhao & Wei Wang. (2021) Disruption of anchoring junctions in the testes of experimental varicocele rats. Experimental and Therapeutic Medicine 22:2.
Crossref
Crossref
Young Soo Oh, Soo Chul Chae, Hwan Kim, Hun Ji Yang, Kyung Jin Lee & Myeong Gu Yeo. (2021) Homeopathic Rhus toxicodendron Induces Cell Adhesions in the Mouse Pre-osteoblast Cell Line MC3T3-e1. Homeopathy 110:02, pages 108-114.
Crossref
Crossref
Korinn N. Murphy & Amanda J. Brinkworth. (2021) Manipulation of Focal Adhesion Signaling by Pathogenic Microbes. International Journal of Molecular Sciences 22:3, pages 1358.
Crossref
Crossref
Justin T Gunesch, Amera L Dixon, Tasneem AM Ebrahim, Melissa M Berrien-Elliott, Swetha Tatineni, Tejas Kumar, Everardo Hegewisch-Solloa, Todd A Fehniger & Emily M Mace. (2020) CD56 regulates human NK cell cytotoxicity through Pyk2. eLife 9.
Crossref
Crossref
Ross J. Collins, Liam D. Morgan, Sioned Owen, Fiona Ruge, Wen G. Jiang & Andrew J. Sanders. (2018) Mechanistic insights of epithelial protein lost in neoplasm in prostate cancer metastasis. International Journal of Cancer 143:10, pages 2537-2550.
Crossref
Crossref
Rayan Naser, Abdullah Aldehaiman, Escarlet Díaz-Galicia & Stefan Arold. (2018) Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development. Cancers 10:6, pages 196.
Crossref
Crossref
Jose-Andres C. Portillo, Luis Muniz-Feliciano, Yalitza Lopez Corcino, So Jung Lee, Jennifer Van Grol, Sarah J. Parsons, William P. Schiemman & Carlos S. Subauste. (2017) Toxoplasma gondii induces FAK-Src-STAT3 signaling during infection of host cells that prevents parasite targeting by autophagy. PLOS Pathogens 13:10, pages e1006671.
Crossref
Crossref
Sara Taleahmad, Mehdi Mirzaei, Azam Samadian, Seyedeh-Nafiseh Hassani, Paul A. Haynes, Ghasem Hosseini Salekdeh & Hossein Baharvand. (2017) Low Focal Adhesion Signaling Promotes Ground State Pluripotency of Mouse Embryonic Stem Cells. Journal of Proteome Research 16:10, pages 3585-3595.
Crossref
Crossref
Monika Raab, Yuning Lu, Karsten Kohler, Xin Smith, Klaus Strebhardt & Christopher E. Rudd. (2017) LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation. Nature Communications 8:1.
Crossref
Crossref
Gao-Feng Zha, Hua-Li Qin, Bahaa G.M. Youssif, Muhammad Wahab Amjad, Maria Abdul Ghafoor Raja, Ahmed H. Abdelazeem & Syed Nasir Abbas Bukhari. (2017) Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance. European Journal of Medicinal Chemistry 135, pages 34-48.
Crossref
Crossref
Laura A Lindsay, Samson N Dowland & Christopher R Murphy. (2016) Uterine focal adhesions are retained at implantation after rat ovarian hyperstimulation. Reproduction 152:6, pages 753-763.
Crossref
Crossref
Luis G. Villa-Diaz, Jin Koo Kim, Alex Laperle, Sean P. Palecek & Paul H. Krebsbach. (2016) Inhibition of Focal Adhesion Kinase Signaling by Integrin α6β1 Supports Human Pluripotent Stem Cell Self-Renewal. Stem Cells 34:7, pages 1753-1764.
Crossref
Crossref
Varadharajan Thiyagarajan, Shin-Hung Lin, Yu-Chuan Chang & Ching-Feng Weng. (2016) Identification of novel FAK and S6K1 dual inhibitors from natural compounds via ADMET screening and molecular docking. Biomedicine & Pharmacotherapy 80, pages 52-62.
Crossref
Crossref
Moumita Banerjee, Qiming Duan & Zijian Xie. (2015) SH2 Ligand-Like Effects of Second Cytosolic Domain of Na/K-ATPase α1 Subunit on Src Kinase. PLOS ONE 10:11, pages e0142119.
Crossref
Crossref
Daniela Sarmiento, Ignacio Montorfano, Mónica Cáceres, César Echeverría, Ricardo Fernández, Claudio Cabello-Verrugio, Oscar Cerda, Pablo Tapia & Felipe Simon. (2014) Endotoxin-induced vascular endothelial cell migration is dependent on TLR4/NF-κB pathway, NAD(P)H oxidase activation, and transient receptor potential melastatin 7 calcium channel activity. The International Journal of Biochemistry & Cell Biology 55, pages 11-23.
Crossref
Crossref
Shibnath Ghatak, Suniti Misra, Russell A. Norris, Ricardo A. Moreno-Rodriguez, Stanley Hoffman, Robert A. Levine, Vincent C. Hascall & Roger R. Markwald. (2014) Periostin Induces Intracellular Cross-talk between Kinases and Hyaluronan in Atrioventricular Valvulogenesis. Journal of Biological Chemistry 289:12, pages 8545-8561.
Crossref
Crossref
Terhi P. Teräväinen, Satu M. Myllymäki, Jens Friedrichs, Nico Strohmeyer, Jose V. Moyano, Chuanyue Wu, Karl S. Matlin, Daniel J. Muller & Aki Manninen. (2013) αV-Integrins Are Required for Mechanotransduction in MDCK Epithelial Cells. PLoS ONE 8:8, pages e71485.
Crossref
Crossref
Varadharajan Thiyagarajan, Shih-Hung Lin, Yi-Chen Chia & Ching-Feng Weng. (2013) A novel inhibitor, 16-hydroxy-cleroda-3,13-dien-16,15-olide, blocks the autophosphorylation site of focal adhesion kinase (Y397) by molecular docking. Biochimica et Biophysica Acta (BBA) - General Subjects 1830:8, pages 4091-4101.
Crossref
Crossref
Irina Alho, Luís Costa, Manuel Bicho & Constança Coelho. (2013) The role of low-molecular-weight protein tyrosine phosphatase (LMW-PTP ACP1) in oncogenesis. Tumor Biology 34:4, pages 1979-1989.
Crossref
Crossref
Hanna E. Lindfors, Jan Wouter Drijfhout & Marcellus Ubbink. (2012) The Src SH2 domain interacts dynamically with the focal adhesion kinase binding site as demonstrated by paramagnetic nmr spectroscopy. IUBMB Life 64:6, pages 538-544.
Crossref
Crossref
Ramesh M. Ray, Chunying Li, Sujoy Bhattacharya, Anjaparavanda P. Naren & Leonard R. Johnson. (2012) Spermine, a molecular switch regulating EGFR, integrin β3, Src, and FAK scaffolding. Cellular Signalling 24:4, pages 931-942.
Crossref
Crossref
Seungwon Yang & Hyun-Man Kim. (2012) The RhoA-ROCK-PTEN pathway as a molecular switch for anchorage dependent cell behavior. Biomaterials 33:10, pages 2902-2915.
Crossref
Crossref
Tyson P. Eucker & Michael E. Konkel. (2012) The cooperative action of bacterial fibronectin-binding proteins and secreted proteins promote maximal Campylobacter jejuni invasion of host cells by stimulating membrane ruffling. Cellular Microbiology 14:2, pages 226-238.
Crossref
Crossref
Edita Aksamitiene, Sirisha Achanta, Walter Kolch, Boris N. Kholodenko, Jan B. Hoek & Anatoly Kiyatkin. (2011) Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells. Cellular Signalling 23:11, pages 1794-1805.
Crossref
Crossref
Tzvetanka Bondeva, Stefanie Wojciech & Gunter Wolf. (2011) Advanced glycation end products inhibit adhesion ability of differentiated podocytes in a neuropilin-1-dependent manner. American Journal of Physiology-Renal Physiology 301:4, pages F852-F870.
Crossref
Crossref
Bo Liu, Shaoying Lu, Shuai Zheng, Zonglai Jiang & Yingxiao Wang. (2011) Two distinct phases of calcium signalling under flow. Cardiovascular Research 91:1, pages 124-133.
Crossref
Crossref
Chunwei Shi, Jia Lu, Wen Wu, Fanxin Ma, Joseph Georges, Hanju Huang, James Balducci, Yongchang Chang & Yao Huang. (2011) Endothelial Cell-Specific Molecule 2 (ECSM2) Localizes to Cell-Cell Junctions and Modulates bFGF-Directed Cell Migration via the ERK-FAK Pathway. PLoS ONE 6:6, pages e21482.
Crossref
Crossref
Banibrata Sen & Faye M. Johnson. (2011) Regulation of Src Family Kinases in Human Cancers. Journal of Signal Transduction 2011, pages 1-14.
Crossref
Crossref
Bernardo A. Mainou & Terence S. Dermody. (2011) Src Kinase Mediates Productive Endocytic Sorting of Reovirus during Cell Entry. Journal of Virology 85:7, pages 3203-3213.
Crossref
Crossref
Xanthippi AlexiFedor BerditchevskiElena Odintsova. (2011) The effect of cell–ECM adhesion on signalling via the ErbB family of growth factor receptors. Biochemical Society Transactions 39:2, pages 568-573.
Crossref
Crossref
T-H Chen, P-C Chan, C-L Chen & H-C Chen. (2010) Phosphorylation of focal adhesion kinase on tyrosine 194 by Met leads to its activation through relief of autoinhibition. Oncogene 30:2, pages 153-166.
Crossref
Crossref
John P. Lydon & Bert W. O'Malley. (2011) Minireview: Steroid Receptor Coactivator-3: A Multifarious Coregulator in Mammary Gland Metastasis. Endocrinology 152:1, pages 19-25.
Crossref
Crossref
Weiwen Long, Ping Yi, Larbi Amazit, Heather L. LaMarca, Felicity Ashcroft, Rakesh Kumar, Michael A. Mancini, Sophia Y. Tsai, Ming-Jer Tsai & Bert W. O'Malley. (2010) SRC-3Δ4 Mediates the Interaction of EGFR with FAK to Promote Cell Migration. Molecular Cell 37:3, pages 321-332.
Crossref
Crossref
Jay S Desgrosellier, Leo A Barnes, David J Shields, Miller Huang, Steven K Lau, Nicolas Prévost, David Tarin, Sanford J Shattil & David A Cheresh. (2009) An integrin αvβ3–c-Src oncogenic unit promotes anchorage-independence and tumor progression. Nature Medicine 15:10, pages 1163-1169.
Crossref
Crossref
M. P. Kim, S. I. Park, S. Kopetz & G. E. Gallick. (2008) Src family kinases as mediators of endothelial permeability: effects on inflammation and metastasis. Cell and Tissue Research 335:1, pages 249-259.
Crossref
Crossref
G. Daoud, F. Le bellego & J. Lafond. (2008) PP2 Regulates Human Trophoblast Cells Differentiation by Activating p38 and ERK1/2 and Inhibiting FAK Activation. Placenta 29:10, pages 862-870.
Crossref
Crossref
Haruko Hayasaka, Karen H. Martin, E. Daniel Hershey & J. Thomas Parsons. (2007) Disruption of FRNK expression by gene targeting of the intronic promoter within the focal adhesion kinase gene. Journal of Cellular Biochemistry 102:4, pages 947-954.
Crossref
Crossref
Min-A Oh, Eun-Sil Kang, Sin-Ae Lee, Eun-Ok Lee, Yong-Bae Kim, Sung-Hoon Kim & Jung Weon Lee. (2007) PKCδ and cofilin activation affects peripheral actin reorganization and cell-cell contact in cells expressing integrin α5 but not its tailless mutant. Journal of Cell Science 120:15, pages 2717-2730.
Crossref
Crossref
Xiaohua Jiang, James Sinnett-Smith & Enrique Rozengurt. (2007) Differential FAK phosphorylation at Ser-910, Ser-843 and Tyr-397 induced by angiotensin II, LPA and EGF in intestinal epithelial cells. Cellular Signalling 19:5, pages 1000-1010.
Crossref
Crossref
Houda Jallal, Maria-Luisa Valentino, Gaoping Chen, Frank Boschelli, Suhad Ali & Shafaat A. Rabbani. (2007)
A Src/Abl Kinase Inhibitor, SKI-606, Blocks Breast Cancer Invasion, Growth, and Metastasis
In vitro
and
In vivo
. Cancer Research 67:4, pages 1580-1588.
Crossref
Crossref
Rodrigo Jacamo, Xiaohua Jiang, J. Adrian Lunn & Enrique Rozengurt. (2007) FAK phosphorylation at Ser-843 inhibits Tyr-397 phosphorylation, cell spreading and migration. Journal of Cellular Physiology 210:2, pages 436-444.
Crossref
Crossref
Yingxiao Wang & Shu Chien. 2007. Integrins. Integrins
177
201
.
Andree Blaukat. 2007. xPharm: The Comprehensive Pharmacology Reference. xPharm: The Comprehensive Pharmacology Reference
1
10
.
Jean-Marc Corsi, Evelyne Rouer, Jean-Antoine Girault & Hervé Enslen. (2006) Organization and post-transcriptional processing of focal adhesion kinase gene. BMC Genomics 7:1.
Crossref
Crossref
Mohanan Valiya Veettil, Neelam Sharma-Walia, Sathish Sadagopan, Hari Raghu, Ramu Sivakumar, Pramod P. Naranatt & Bala Chandran. (2006) RhoA-GTPase Facilitates Entry of Kaposi's Sarcoma-Associated Herpesvirus into Adherent Target Cells in a Src-Dependent Manner. Journal of Virology 80:23, pages 11432-11446.
Crossref
Crossref
P I Poulikakos, G-H Xiao, R Gallagher, S Jablonski, S C Jhanwar & J R Testa. (2006) Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAK. Oncogene 25:44, pages 5960-5968.
Crossref
Crossref
Xiaohua Jiang, Rodrigo Jacamo, Elena Zhukova, James Sinnett-Smith & Enrique Rozengurt. (2006) RNA interference reveals a differential role of FAK and Pyk2 in cell migration, leading edge formation and increase in focal adhesions induced by LPA in intestinal epithelial cells. Journal of Cellular Physiology 207:3, pages 816-828.
Crossref
Crossref
Yingxiao Wang, Gang Jin, Hui Miao, Julie Y.-S. Li, Shunichi Usami & Shu Chien. (2006) Integrins regulate VE-cadherin and catenins: Dependence of this regulation on Src, but not on Ras. Proceedings of the National Academy of Sciences 103:6, pages 1774-1779.
Crossref
Crossref
Joo Hong Woo, Jeong Heon Kim, Inhee Mook-Jung & Hye Sun Kim. (2006) Lipid products of phosphoinositide 3-kinase abrogate genistein-induced fusion inhibition in myoblasts. European Journal of Pharmacology 529:1-3, pages 84-94.
Crossref
Crossref
Rodrigo O. Jácamo & Enrique Rozengurt. (2005) A truncated FAK lacking the FERM domain displays high catalytic activity but retains responsiveness to adhesion-mediated signals. Biochemical and Biophysical Research Communications 334:4, pages 1299-1304.
Crossref
Crossref
Robert S. Fan, Rodrigo O. Jácamo, Xiaohua Jiang, James Sinnett-Smith & Enrique Rozengurt. (2005) G Protein-coupled Receptor Activation Rapidly Stimulates Focal Adhesion Kinase Phosphorylation at Ser-843. Journal of Biological Chemistry 280:25, pages 24212-24220.
Crossref
Crossref
Yoshihiro Mimura, Hironobu Ihn, Masatoshi Jinnin, Yoshihide Asano, Kenichi Yamane & Kunihiko Tamaki. (2005) Constitutive Phosphorylation of Focal Adhesion Kinase Is Involved in the Myofibroblast Differentiation of Scleroderma Fibroblasts. Journal of Investigative Dermatology 124:5, pages 886-892.
Crossref
Crossref
Michelle K.Y. Siu & C. Yan Cheng. (2004) Extracellular Matrix: Recent Advances on Its Role in Junction Dynamics in the Seminiferous Epithelium During Spermatogenesis1. Biology of Reproduction 71:2, pages 375-391.
Crossref
Crossref
Annika Armulik, Teet Velling & Staffan Johansson. (2004) The Integrin β1 Subunit Transmembrane Domain Regulates Phosphatidylinositol 3-Kinase-dependent Tyrosine Phosphorylation of Crk-associated Substrate. Molecular Biology of the Cell 15:6, pages 2558-2567.
Crossref
Crossref
Mark S. Duxbury, Hiromichi Ito, Stanley W. Ashley & Edward E. Whang. (2004) CEACAM6 Cross-linking Induces Caveolin-1-dependent, Src-mediated Focal Adhesion Kinase Phosphorylation in BxPC3 Pancreatic Adenocarcinoma Cells. Journal of Biological Chemistry 279:22, pages 23176-23182.
Crossref
Crossref
Dayanand D. Deo, Nicolas G. Bazan & Jay D. Hunt. (2004) Activation of Platelet-activating Factor Receptor-coupled Gαq Leads to Stimulation of Src and Focal Adhesion Kinase via Two Separate Pathways in Human Umbilical Vein Endothelial Cells. Journal of Biological Chemistry 279:5, pages 3497-3508.
Crossref
Crossref
Victor A. Levin. 2004. Molecular Targeting and Signal Transduction. Molecular Targeting and Signal Transduction
89
119
.
Peggy Lévy, Hélène Robin, France Bertrand, Michel Kornprobst & Jacqueline Capeau. (2003) Butyrate-treated colonic Caco-2 cells exhibit defective integrin-mediated signaling together with increased apoptosis and differentiation. Journal of Cellular Physiology 197:3, pages 336-347.
Crossref
Crossref
Meghna U. NaikUlhas P. Naik. (2003) Calcium-and integrin-binding protein regulates focal adhesion kinase activity during platelet spreading on immobilized fibrinogen. Blood 102:10, pages 3629-3636.
Crossref
Crossref
Gress Kadaré, Madeleine Toutant, Etienne Formstecher, Jean-Christophe Corvol, Michèle Carnaud, Marie-Claude Boutterin & Jean-Antoine Girault. (2003) PIAS1-mediated Sumoylation of Focal Adhesion Kinase Activates Its Autophosphorylationn. Journal of Biological Chemistry 278:48, pages 47434-47440.
Crossref
Crossref
Qin Wang, Gordon R. PfeifferIIII & William A. Gaarde. (2003) Activation of SRC Tyrosine Kinases in Response to ICAM-1 Ligation in Pulmonary Microvascular Endothelial Cells. Journal of Biological Chemistry 278:48, pages 47731-47743.
Crossref
Crossref
Elisa Giannoni, Paola Chiarugi, Giacomo Cozzi, Lucia Magnelli, Maria Letizia Taddei, Tania Fiaschi, Francesca Buricchi, Giovanni Raugei & Giampietro Ramponi. (2003) Lymphocyte Function-associated Antigen-1-mediated T Cell Adhesion Is Impaired by Low Molecular Weight Phosphotyrosine Phosphatase-dependent Inhibition of FAK Activity. Journal of Biological Chemistry 278:38, pages 36763-36776.
Crossref
Crossref
Dita Gratzinger, Sandra Canosa, Britta Engelhardt & Joseph A. Maori. (2003) Platelet endothelial cell adhesion molecule‐1 modulates endothelial cell motility through the small G‐protein Rho. The FASEB Journal 17:11, pages 1458-1469.
Crossref
Crossref
Jérôme Cornillon, Lydia Campos & Denis Guyotat. (2003)
Focal adhesion kinase
(FAK), une protéine aux fonctions multiples
. médecine/sciences 19:6-7, pages 743-752.
Crossref
Crossref
Eduardo Perez Salazar, Isabel Hunger-Glaser & Enrique Rozengurt. (2003) Dissociation of focal adhesion kinase and paxillin tyrosine phosphorylation induced by bombesin and lysophosphatidic acid from epidermal growth factor receptor transactivation in Swiss 3T3 cells. Journal of Cellular Physiology 194:3, pages 314-324.
Crossref
Crossref
Dita Gratzinger, Mark Barreuther & Joseph A Madri. (2003) Platelet–endothelial cell adhesion molecule-1 modulates endothelial migration through its immunoreceptor tyrosine-based inhibitory motif. Biochemical and Biophysical Research Communications 301:1, pages 243-249.
Crossref
Crossref
Tzeng-Horng Leu & Ming-Chei Maa. (2002) Tyr-863 phosphorylation enhances focal adhesion kinase autophosphorylation at Tyr-397. Oncogene 21:46, pages 6992-7000.
Crossref
Crossref
Yi-Ping Jin, Ram Pyare Singh, Ze-Ying Du, Ayyappan K. Rajasekaran, Enrique Rozengurt & Elaine F. Reed. (2002) Ligation of HLA Class I Molecules on Endothelial Cells Induces Phosphorylation of Src, Paxillin, and Focal Adhesion Kinase in an Actin-Dependent Manner. The Journal of Immunology 168:11, pages 5415-5423.
Crossref
Crossref
Margaret C. Frame. (2002) Src in cancer: deregulation and consequences for cell behaviour. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1602:2, pages 114-130.
Crossref
Crossref
Fubo Liang & Chan Fong Chang. (2001) Signalling of GPI-anchored CD157 via focal adhesion kinase in MCA102 fibroblasts. FEBS Letters 506:3, pages 207-210.
Crossref
Crossref
Ninad V. Prabhu, Subeeh A. Siddiqui, John S. McMurray & B. Montgomery Pettitt. (2001)
Structural basis for the activity of pp60
c-src
protein tyrosine kinase inhibitors
. Biopolymers 59:3, pages 167-179.
Crossref
Crossref
Michelle D. Haskell, Jill K. Slack, J. Thomas Parsons & Sarah J. Parsons. (2001) c-Src Tyrosine Phosphorylation of Epidermal Growth Factor Receptor, P190 RhoGAP, and Focal Adhesion Kinase Regulates Diverse Cellular Processes. Chemical Reviews 101:8, pages 2425-2440.
Crossref
Crossref
Takefumi Shono, Yasushi Mochizuki, Hiroshi Kanetake & Shigeru Kanda. (2001) Inhibition of FGF-2-Mediated Chemotaxis of Murine Brain Capillary Endothelial Cells by Cyclic RGDfV Peptide through Blocking the Redistribution of c-Src into Focal Adhesions. Experimental Cell Research 268:2, pages 169-178.
Crossref
Crossref
Jian-Kang Chen, Joe Zimpelmann, Raymond C. Harris & Kevin D. Burns. (2001) Angiotensin IV induces tyrosine phosphorylation of focal adhesion kinase and paxillin in proximal tubule cells. American Journal of Physiology-Renal Physiology 280:6, pages F980-F988.
Crossref
Crossref
Irena Mlinaric-Rascan & Tadashi Yamamoto. (2001) B cell receptor signaling involves physical and functional association of FAK with Lyn and IgM. FEBS Letters 498:1, pages 26-31.
Crossref
Crossref
Eduardo Perez Salazar & Enrique Rozengurt. (2001) Src Family Kinases Are Required for Integrin-mediated but Not for G Protein-coupled Receptor Stimulation of Focal Adhesion Kinase Autophosphorylation at Tyr-397. Journal of Biological Chemistry 276:21, pages 17788-17795.
Crossref
Crossref
Takefumi Shono, Hiroshi Kanetake & Shigeru Kanda. (2001) The Role of Mitogen-Activated Protein Kinase Activation within Focal Adhesions in Chemotaxis toward FGF-2 by Murine Brain Capillary Endothelial Cells. Experimental Cell Research 264:2, pages 275-283.
Crossref
Crossref
Marcus Achison, Catherine M. Elton, Philip G. Hargreaves, C. Graham Knight, Michael J. Barnes & Richard W. Farndale. (2001) Integrin-independent Tyrosine Phosphorylation of p125fak in Human Platelets Stimulated by Collagen. Journal of Biological Chemistry 276:5, pages 3167-3174.
Crossref
Crossref
Wei Li, Aydin Duzgun, Bauer E. Sumpio & Marc D. Basson. (2001) Integrin and FAK-mediated MAPK activation is required for cyclic strain mitogenic effects in Caco-2 cells. American Journal of Physiology-Gastrointestinal and Liver Physiology 280:1, pages G75-G87.
Crossref
Crossref
Jeffrey D Bjorge, Andrew Jakymiw & Donald J Fujita. (2000) Selected glimpses into the activation and function of Src kinase. Oncogene 19:49, pages 5620-5635.
Crossref
Crossref
Marpadga A. Reddy, Carol A. Wass, Kwang Sik Kim, David D. Schlaepfer & Nemani V. Prasadarao. (2000)
Involvement of Focal Adhesion Kinase in
Escherichia coli
Invasion of Human Brain Microvascular Endothelial Cells
. Infection and Immunity 68:11, pages 6423-6430.
Crossref
Crossref
Josée N. Lavoie, Claudia Champagne, Marie-Claude Gingras & Amélie Robert. (2000) Adenovirus E4 Open Reading Frame 4–Induced Apoptosis Involves Dysregulation of Src Family Kinases. Journal of Cell Biology 150:5, pages 1037-1056.
Crossref
Crossref
Victor Nurcombe, Chanel E. Smart, Hiram Chipperfield, Simon M. Cool, Benoni Boilly & Hubert Hondermarck. (2000) The Proliferative and Migratory Activities of Breast Cancer Cells Can Be Differentially Regulated by Heparan Sulfates. Journal of Biological Chemistry 275:39, pages 30009-30018.
Crossref
Crossref
Gordon W. McLean, Valerie J. Fincham & Margaret C. Frame. (2000) v-Src Induces Tyrosine Phosphorylation of Focal Adhesion Kinase Independently of Tyrosine 397 and Formation of a Complex with Src. Journal of Biological Chemistry 275:30, pages 23333-23339.
Crossref
Crossref
Alla Danilkovitch-Miagkova, Debora Angeloni, Alison Skeel, Shannon Donley, Michael Lerman & Edward J. Leonard. (2000) Integrin-mediated RON Growth Factor Receptor Phosphorylation Requires Tyrosine Kinase Activity of Both the Receptor and c-Src. Journal of Biological Chemistry 275:20, pages 14783-14786.
Crossref
Crossref
Ji-He Zhao & Jun-Lin Guan. 2000. Signaling Through the Cell Matrix. Signaling Through the Cell Matrix
37
55
.
Jeffrey W. Thomas, Marion A. Cooley, Jill M. Broome, Ravi Salgia, James D. Griffin, Christian R. Lombardo & Michael D. Schaller. (1999) The Role of Focal Adhesion Kinase Binding in the Regulation of Tyrosine Phosphorylation of Paxillin. Journal of Biological Chemistry 274:51, pages 36684-36692.
Crossref
Crossref
Yoshiyuki Ohashi, Satoshi Iwata, Kenjiro Kamiguchi & Chikao Morimoto. (1999) Tyrosine Phosphorylation of Crk-Associated Substrate Lymphocyte-Type Is a Critical Element in TCR- and β1 Integrin-Induced T Lymphocyte Migration. The Journal of Immunology 163:7, pages 3727-3734.
Crossref
Crossref
Michael D. Schaller, Jeffrey D. Hildebrand & J. Thomas Parsons. (1999) Complex Formation with Focal Adhesion Kinase: A Mechanism to Regulate Activity and Subcellular Localization of Src Kinases. Molecular Biology of the Cell 10:10, pages 3489-3505.
Crossref
Crossref
Eduardo Perez Salazar & Enrique Rozengurt. (1999) Bombesin and Platelet-derived Growth Factor Induce Association of Endogenous Focal Adhesion Kinase with Src in Intact Swiss 3T3 Cells. Journal of Biological Chemistry 274:40, pages 28371-28378.
Crossref
Crossref
Paola Defilippi, Cristina Olivo, Mascia Venturino, Laura Dolce, Lorenzo Silengo & Guido Tarone. (1999) Actin cytoskeleton organization in response to integrin-mediated adhesion. Microscopy Research and Technique 47:1, pages 67-78.
Crossref
Crossref
David D Schlaepfer, Christof R Hauck & David J Sieg. (1999) Signaling through focal adhesion kinase. Progress in Biophysics and Molecular Biology 71:3-4, pages 435-478.
Crossref
Crossref
Xiong Li, Ruth C. Dy, William G. Cance, Lee M. Graves & H. Shelton Earp. (1999) Interactions between Two Cytoskeleton-associated Tyrosine Kinases: Calcium-dependent Tyrosine Kinase and Focal Adhesion Tyrosine Kinase. Journal of Biological Chemistry 274:13, pages 8917-8924.
Crossref
Crossref
Yoshihiko Yamakita, Go Totsukawa, Shigeko Yamashiro, David Fry, Xiaoe Zhang, Steven K. Hanks & Fumio Matsumura. (1999) Dissociation of FAK/p130CAS/c-Src Complex during Mitosis: Role of Mitosis-specific Serine Phosphorylation of FAK. Journal of Cell Biology 144:2, pages 315-324.
Crossref
Crossref
Debbie A. Law & David R. Phillips. 1999. Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease. Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease
35
66
.
Jean-Antoine Girault, Gilles Labesse, Jean-Paul Mornon & Isabelle Callebaut. (1998) Janus Kinases and Focal Adhesion Kinases Play in the 4.1 Band: A Superfamily of Band 4.1 Domains Important for Cell Structure and Signal Transduction. Molecular Medicine 4:12, pages 751-769.
Crossref
Crossref
Sandrine Etienne, Peter Adamson, John Greenwood, A. Donny Strosberg, Sylvie Cazaubon & Pierre-Olivier Couraud. (1998) ICAM-1 Signaling Pathways Associated with Rho Activation in Microvascular Brain Endothelial Cells. The Journal of Immunology 161:10, pages 5755-5761.
Crossref
Crossref
Carlos O. Arregui, Janne Balsamo & Jack Lilien. (1998) Impaired Integrin-mediated Adhesion and Signaling in Fibroblasts Expressing a Dominant-negative Mutant PTP1B. Journal of Cell Biology 143:3, pages 861-873.
Crossref
Crossref
Qinghua Wang, Philip J. Bilan & Amira Klip. (1998) Opposite Effects of Insulin on Focal Adhesion Proteins in 3T3-L1 Adipocytes and in Cells Overexpressing the Insulin Receptor. Molecular Biology of the Cell 9:11, pages 3057-3069.
Crossref
Crossref
Patricia Lebrun, Isabelle Mothe-Satney, Laurent Delahaye, Emmanuel Van Obberghen & Véronique Baron. (1998) Insulin Receptor Substrate-1 as a Signaling Molecule for Focal Adhesion Kinase pp125FAK and pp60. Journal of Biological Chemistry 273:48, pages 32244-32253.
Crossref
Crossref
P.J. Bartholomew, J.M. Vinci & J.A. DePasquale. (1998) Decreased tyrosine phosphorylation of focal adhesion kinase after estradiol treatment of MCF-7 human breast carcinoma cells. The Journal of Steroid Biochemistry and Molecular Biology 67:3, pages 241-249.
Crossref
Crossref
Barbara Valentinis, Krzysztof Reiss & Renato Baserga. (1998) Insulin-like growth factor-I-mediated survival from Anoikis: Role of cell aggregation and focal adhesion kinase. Journal of Cellular Physiology 176:3, pages 648-657.
Crossref
Crossref
José Luis Rodrı́guez-Fernández & Enrique Rozengurt. (1998) Bombesin, Vasopressin, Lysophosphatidic Acid, and Sphingosylphosphorylcholine Induce Focal Adhesion Kinase Activation in Intact Swiss 3T3 Cells. Journal of Biological Chemistry 273:30, pages 19321-19328.
Crossref
Crossref
Theresa M. LaVallee, Igor A. Prudovsky, Grainne A. McMahon, Xiaoguo Hu & Thomas Maciag. (1998) Activation of the MAP Kinase Pathway by FGF-1 Correlates with Cell Proliferation Induction While Activation of the Src Pathway Correlates with Migration. The Journal of Cell Biology 141:7, pages 1647-1658.
Crossref
Crossref
Rosemarie Fernandez & Suzanne J. Suchard. (1998) Syk Activation Is Required for Spreading and H2O2 Release in Adherent Human Neutrophils. The Journal of Immunology 160:10, pages 5154-5162.
Crossref
Crossref
Jason S. Felsch, Teresa G. Cachero & Ernest G. Peralta. (1998) Activation of protein tyrosine kinase PYK2 by the m1 muscarinic acetylcholine receptor. Proceedings of the National Academy of Sciences 95:9, pages 5051-5056.
Crossref
Crossref
Yu Shen, Galen Schneider, Jean-François Cloutier, André Veillette & Michael D. Schaller. (1998) Direct Association of Protein-tyrosine Phosphatase PTP-PEST with Paxillin. Journal of Biological Chemistry 273:11, pages 6474-6481.
Crossref
Crossref
Xiang-Qun Hu, Namita Singh, Debabrata Mukhopadhyay & Hamid I. Akbarali. (1998) Modulation of Voltage-dependent Ca2+Channels in Rabbit Colonic Smooth Muscle Cells by c-Src and Focal Adhesion Kinase. Journal of Biological Chemistry 273:9, pages 5337-5342.
Crossref
Crossref
Jeffrey W. Thomas, Byron Ellis, Renee J. Boerner, Wilson B. Knight, Gilbert C. WhiteIIII & Michael D. Schaller. (1998) SH2- and SH3-mediated Interactions between Focal Adhesion Kinase and Src. Journal of Biological Chemistry 273:1, pages 577-583.
Crossref
Crossref
Sheila M. Thomas & Joan S. Brugge. (1997) CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES. Annual Review of Cell and Developmental Biology 13:1, pages 513-609.
Crossref
Crossref
Majed M. Hamawy, Mark Swieter, Stephan E. Mergenhagen & Reuben P. Siraganian. (1997) Reconstitution of High Affinity IgE Receptor-mediated Secretion By Transfecting Protein Tyrosine Kinase pp125FAK. Journal of Biological Chemistry 272:48, pages 30498-30503.
Crossref
Crossref
Kouichi Tachibana, Takeshi Urano, Hiroo Fujita, Yoshiyuki Ohashi, Kenjiro Kamiguchi, Satoshi Iwata, Hisamaru Hirai & Chikao Morimoto. (1997) Tyrosine Phosphorylation of Crk-associated Substrates by Focal Adhesion Kinase. Journal of Biological Chemistry 272:46, pages 29083-29090.
Crossref
Crossref
Anne Astier, Serge N. Manié, Hava Avraham, Hisamaru Hirai, Susan F. Law, Yuzhu Zhang, Erica A. Golemis, Yigong Fu, Brian J. Druker, Nilou Haghayeghi, Arnold S. Freedman & Shalom Avraham. (1997) The Related Adhesion Focal Tyrosine Kinase Differentially Phosphorylates p130Cas and the Cas-like Protein, p105HEF1. Journal of Biological Chemistry 272:32, pages 19719-19724.
Crossref
Crossref
Alexandra M.L. Meijne, Lisette Ruuls-Van Stalle, Constance A. Feltkamp, James B. McCarthy & Ed Roos. (1997) v-src-Induced Cell Shape Changes in Rat Fibroblasts Require New Gene Transcription and Precede Loss of Focal Adhesions. Experimental Cell Research 234:2, pages 477-485.
Crossref
Crossref
Joseph R. Spoonster, Laura Masiero, Sharon A. Savage, Julie Probst & Elise C. Kohn. (1997) Regulation of cell spreading during differentiation in the muscarinic M5 receptor tumor-suppressor model. International Journal of Cancer 72:2, pages 362-368.
Crossref
Crossref
Xiong Li & H. Shelton Earp. (1997) Paxillin Is Tyrosine-phosphorylated by and Preferentially Associates with the Calcium-dependent Tyrosine Kinase in Rat Liver Epithelial Cells. Journal of Biological Chemistry 272:22, pages 14341-14348.
Crossref
Crossref
Oran Ayalon & Benjamin Geiger. (1997) Cyclic changes in the organization of cell adhesions and the associated cytoskeleton, induced by stimulation of tyrosine phosphorylation in bovine aortic endothelial cells. Journal of Cell Science 110:5, pages 547-556.
Crossref
Crossref
Hilary E. Beggs, Steven C. Baragona, John J. Hemperly & Patricia F. Maness. (1997) NCAM140 Interacts with the Focal Adhesion Kinase p125 and the SRC-related Tyrosine Kinase p59. Journal of Biological Chemistry 272:13, pages 8310-8319.
Crossref
Crossref
D. IlicC.H. DamskyT. Yamamoto. (1997) Focal adhesion kinase: at the crossroads of signal transduction. Journal of Cell Science 110:4, pages 401-407.
Crossref
Crossref
Marja Ojaniemi, Stuart S. Martin, Fabrizio Dolfi, Jerrold M. Olefsky & Kristiina Vuori. (1997) The Proto-oncogene Product p120 Links c-Src and Phosphatidylinositol 3′-Kinase to the Integrin Signaling Pathway. Journal of Biological Chemistry 272:6, pages 3780-3787.
Crossref
Crossref
Robin Hesketh. 1997. The Oncogene & Tumour Suppressor Gene Factsbook. The Oncogene & Tumour Suppressor Gene Factsbook
359
368
.
Nicky Konstantopoulos & Stella Clark. (1996) Reduced Cell Attachment and Phosphorylation of Focal Adhesion Kinase Associated with Expression of a Mutant Insulin Receptor. Journal of Biological Chemistry 271:46, pages 28960-28968.
Crossref
Crossref
Hong-Chen Chen, Paul A. Appeddu, Hiroko Isoda & Jun-Lin Guan. (1996) Phosphorylation of Tyrosine 397 in Focal Adhesion Kinase Is Required for Binding Phosphatidylinositol 3-Kinase. Journal of Biological Chemistry 271:42, pages 26329-26334.
Crossref
Crossref
L.A. CaryJ.F. ChangJ.L. Guan. (1996) Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. Journal of Cell Science 109:7, pages 1787-1794.
Crossref
Crossref
Megan T. Brown & Jonathan A. Cooper. (1996) Regulation, substrates and functions of src. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1287:2-3, pages 121-149.
Crossref
Crossref
Hideharu Odai, Ko Sasaki, Yutaka Hanazono, Hiroo Ueno, Tomoyuki Tanaka, Kiyoshi Miyagawa, Kinuko Mitani, Yoshio Yazaki & Hisamaru Hirai. (1995)
c-Cbl Is Inducibly Tyrosine-phosphorylated by Epidermal Growth Factor Stimulation in Fibroblasts, and Constitutively Tyrosine-phosphorylated and Associated with v-Src in v-
src
-transformed Fibroblasts
. Japanese Journal of Cancer Research 86:12, pages 1119-1126.
Crossref
Crossref
K B Kaplan, J R Swedlow, D O Morgan & H E Varmus. (1995) c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism.. Genes & Development 9:12, pages 1505-1517.
Crossref
Crossref
Jason A. Estep, Lu O. Sun & Martin Riccomagno. (2022) A Luciferase Fragment Complementation Assay to Detect Focal Adhesion Kinase (FAK) Signaling Events. SSRN Electronic Journal.
Crossref
Crossref