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Research Article

Insulin Receptor Substrate 1 Rescues Insulin Action in CHO Cells Expressing Mutant Insulin Receptors That Lack a Juxtamembrane NPXY Motif

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Pages 4711-4717 | Received 29 Mar 1995, Accepted 26 May 1995, Published online: 30 Mar 2023

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Read on this site (2)

Jens C. Brüning, Jonathon Winnay, Bentley Cheatham & C. Ronald Kahn. (1997) Differential Signaling by Insulin Receptor Substrate 1 (IRS-1) and IRS-2 in IRS-1-Deficient Cells. Molecular and Cellular Biology 17:3, pages 1513-1521.
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Toshimasa Yamauchi, Kazuyuki Tobe, Hiroyuki Tamemoto, Kohjiro Ueki, Yasushi Kaburagi, Ritsuko Yamamoto-Honda, Yoshihiko Takahashi, Fumiaki Yoshizawa, Shinichi Aizawa, Yasuo Akanuma, Nahum Sonenberg, Yoshio Yazaki & Takashi Kadowaki. (1996) Insulin Signalling and Insulin Actions in the Muscles and Livers of Insulin-Resistant, Insulin Receptor Substrate 1-Deficient Mice. Molecular and Cellular Biology 16:6, pages 3074-3084.
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Articles from other publishers (17)

Thangiah Geetha, Shraddha D. Rege, Salome E. Mathews, Susan O. Meakin, Morris F. White & Jeganathan Ramesh Babu. (2013) Nerve Growth Factor Receptor TrkA, a New Receptor in Insulin Signaling Pathway in PC12 Cells. Journal of Biological Chemistry 288:33, pages 23807-23813.
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Daniela F Bertelli, Andressa Coope, Andrea M Caricilli, Patricia O Prada, Mario J Saad, Licio A Velloso & Eliana P Araujo. (2013) Inhibition of 72 kDa inositol polyphosphate 5-phosphatase E improves insulin signal transduction in diet-induced obesity. Journal of Endocrinology 217:2, pages 131-140.
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Giorgio Sesti, Massimo Federici, Marta L. Hribal, Davide Lauro, Paolo Sbraccia & Renato Lauro. (2001) Defects of the insulin receptor substrate (IRS) system in human metabolic disorders. The FASEB Journal 15:12, pages 2099-2111.
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Pascal Peraldi, Chantal Filloux, Brice Emanuelli, Douglas J. Hilton & Emmanuel Van Obberghen. (2001) Insulin Induces Suppressor of Cytokine Signaling-3 Tyrosine Phosphorylation through Janus-activated Kinase. Journal of Biological Chemistry 276:27, pages 24614-24620.
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Barbara Giovannone, Maria Lucia Scaldaferri, Massimo Federici, Ottavia Porzio, Davide Lauro, Angelo Fusco, Paolo Sbraccia, Patrizia Borboni, Renato Lauro & Giorgio Sesti. (2000) Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential. Diabetes/Metabolism Research and Reviews 16:6, pages 434-441.
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Giorgio Sesti. (2000) Insulin receptor substrate polymorphisms and Type 2 diabetes mellitus. Pharmacogenomics 1:3, pages 343-357.
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Gaetano Romano, Marco Prisco, Tommaso Zanocco-Marani, Francesca Peruzzi, Barbara Valentinis & Renato Baserga. (1999) Dissociation between resistance to apoptosis and the transformed phenotype in IGF-I receptor signaling. Journal of Cellular Biochemistry 72:2, pages 294-310.
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Jian Wang & Heimo Riedel. (1998) Insulin-like Growth Factor-I Receptor and Insulin Receptor Association with a Src Homology-2 Domain-containing Putative Adapter. Journal of Biological Chemistry 273:6, pages 3136-3139.
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Masashi Yamada, Hiroshi Ohnishi, Shin-ichiro Sano, Atsushi Nakatani, Toshihiko Ikeuchi & Hiroshi Hatanaka. (1997) Insulin Receptor Substrate (IRS)-1 and IRS-2 Are Tyrosine-phosphorylated and Associated with Phosphatidylinositol 3-Kinase in Response to Brain-derived Neurotrophic Factor in Cultured Cerebral Cortical Neurons. Journal of Biological Chemistry 272:48, pages 30334-30339.
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Paulos Berhanu, Celia Anderson, Matt Hickman & Theodore P. Ciaraldi. (1997) Insulin Signal Transduction by a Mutant Human Insulin Receptor Lacking the NPEY Sequence. Journal of Biological Chemistry 272:36, pages 22884-22890.
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Lynne Yenush & Morris F. White. (1997) The IRS-signalling system during insulin and cytokine action. BioEssays 19:6, pages 491-500.
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Jonathan M. Backer, Christina Wjasow & Yitao Zhang. (1997) In Vitro Binding and Phosphorylation of Insulin Receptor Substrate 1 by the Insulin Receptor. Role of Interactions Mediated by the Phosphotyrosine-Binding Domain and the Pleckstrin-Homology Domain. European Journal of Biochemistry 245:1, pages 91-96.
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Steven B. Waters, Kathleen H. Holt, Ann Louise Olson & Jeffrey E. Pessin. 1997. 161 202 .
Hiroo Ueno, Ko Sasaki, Hiroyuki Kozutsumi, Kiyoshi Miyagawa, Kinuko Mitani, Yoshio Yazaki & Hisamaru Hirai. (1996) Growth and Survival Signals transmitted via Two Distinct NPXY Motifs within Leukocyte Tyrosine Kinase, an Insulin Receptor-related Tyrosine Kinase. Journal of Biological Chemistry 271:44, pages 27707-27714.
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Lynne Yenush, Kevin J. Makati, Jennifer Smith-Hall, Osamu Ishibashi, Martin G. MyersJr.Jr. & Morris F. White. (1996) The Pleckstrin Homology Domain Is the Principle Link between the Insulin Receptor and IRS-1. Journal of Biological Chemistry 271:39, pages 24300-24306.
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Marina Holgado-Madruga, David R. Emlet, David K. Moscatello, Andrew K. Godwin & Albert J. Wong. (1996) A Grb2-associated docking protein in EGF- and insulin-receptor signalling. Nature 379:6565, pages 560-564.
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Steven B. Waters & Jeffrey E. Pessin. (1996) Insulin receptor substrate 1 and 2 (IRS1 and IRS2): what a tangled web we weave. Trends in Cell Biology 6:1, pages 1-4.
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