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Research Article

Two Chimeric Receptors of Epidermal Growth Factor Receptor and c-Ros That Differ in Their Transmembrane Domains Have Opposite Effects on Cell Growth

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Pages 1509-1518 | Received 27 Sep 1995, Accepted 28 Jan 1996, Published online: 29 Mar 2023

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Weizhou Zhang, Cong S. Zong, Ulrich Hermanto, Pablo Lopez-Bergami, Ze'ev Ronai & Lu-Hai Wang. (2006) RACK1 Recruits STAT3 Specifically to Insulin and Insulin-Like Growth Factor 1 Receptors for Activation, Which Is Important for Regulating Anchorage-Independent Growth. Molecular and Cellular Biology 26:2, pages 413-424.
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Articles from other publishers (18)

Huihui Li, Xingyu Yan, Man Yang, Mei Liu, Shan Tian, Mengru Yu, Wei-Ping Li & Cong Zhang. (2021) The Impact of PTPRK and ROS1 Polymorphisms on the Preeclampsia Risk in Han Chinese Women. International Journal of Hypertension 2021, pages 1-10.
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Alexander Drilon, Chelsea Jenkins, Sudarshan Iyer, Adam Schoenfeld, Clare Keddy & Monika A. Davare. (2020) ROS1-dependent cancers — biology, diagnostics and therapeutics. Nature Reviews Clinical Oncology 18:1, pages 35-55.
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C-H Shih, Y-J Chang, W-C Huang, T-H Jang, H-J Kung, W-C Wang, M-H Yang, M-C Lin, S-F Huang, S-W Chou, E Chang, H Chiu, T-Y Shieh, Y-J Chen, L-H Wang & L Chen. (2017) EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis. Oncogene 36:47, pages 6542-6554.
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Jennifer L. Hsu & Mien-Chie Hung. (2016) The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer. Cancer and Metastasis Reviews 35:4, pages 575-588.
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Disha Pathak, Navriti Chadha & Om Silakari. (2016) Identification of non-resistant ROS-1 inhibitors using structure based pharmacophore analysis. Journal of Molecular Graphics and Modelling 70, pages 85-93.
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Alain Charest. 2015. Receptor Tyrosine Kinases: Family and Subfamilies. Receptor Tyrosine Kinases: Family and Subfamilies 641 684 .
Kurtis D. Davies & Robert C. Doebele. (2013) Molecular Pathways: ROS1 Fusion Proteins in Cancer. Clinical Cancer Research 19:15, pages 4040-4045.
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Martin R. Jones, Ann M. Rose & David L. Baillie. (2013) The ortholog of the human proto‐oncogene ROS1 is required for epithelial development in C. elegans . genesis 51:8, pages 545-561.
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Hee Jin Lee, Hyang Sook Seol, Joo Young Kim, Sung-Min Chun, Young-Ah Suh, Young-Soo Park, Sang-we Kim, Chang-Min Choi, Seung-Il Park, Dong Kwan Kim, Yong-Hee Kim & Se Jin Jang. (2012) ROS1 Receptor Tyrosine Kinase, a Druggable Target, is Frequently Overexpressed in Non-Small Cell Lung Carcinomas Via Genetic and Epigenetic Mechanisms. Annals of Surgical Oncology 20:1, pages 200-208.
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Jaime Acquaviva, Ricky Wong & Al Charest. (2009) The multifaceted roles of the receptor tyrosine kinase ROS in development and cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1795:1, pages 37-52.
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Trevor G. Cooper, Andrea Wagenfeld, Gail A. Cornwall, Nelson Hsia, Sin Tak Chu, Marie-Claire Orgebin-Crist, Joel Drevet, Patrick Vernet, Cosmina Avram, Eberhard Nieschlag & Ching-Hei Yeung. (2003) Gene and Protein Expression in the Epididymis of Infertile c-ros Receptor Tyrosine Kinase-Deficient Mice1. Biology of Reproduction 69:5, pages 1750-1762.
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Alan Charest, Vicky Kheifets, Julie Park, Keara Lane, Kevin McMahon, Cathy L. Nutt & David Housman. (2003) Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma. Proceedings of the National Academy of Sciences 100:3, pages 916-921.
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Kevin T. Nguyen, Cong S. Zong, Shailaja Uttamsingh, Pallavi Sachdev, Monica Bhanot, Mai-Thao Le, Joseph L.-K. Chan & Lu-Hai Wang. (2002) The Role of Phosphatidylinositol 3-Kinase, Rho Family GTPases, and STAT3 in Ros-induced Cell Transformation. Journal of Biological Chemistry 277:13, pages 11107-11115.
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Anne Gardin, Colette Auzan, Eric Clauser, Tatiana Malherbe, Dominique Aunis, Gérard Crémel & Pierre Hubert. (1999) Substitution of the insulin receptor transmembrane domain with that of glycophorin A inhibits insulin action. The FASEB Journal 13:11, pages 1347-1357.
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Stevan R Hubbard. (1999) Structural analysis of receptor tyrosine kinases. Progress in Biophysics and Molecular Biology 71:3-4, pages 343-358.
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Cong S. Zong, Liyu Zeng, Yixing Jiang, Henry B. Sadowski & Lu-Hai Wang. (1998) Stat3 Plays an Important Role in Oncogenic Ros- and Insulin-like Growth Factor I Receptor-induced Anchorage-independent Growth. Journal of Biological Chemistry 273:43, pages 28065-28072.
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David H Jones, Kathryn R Barber & Chris W.M Grant. (1998) Sequence-related behaviour of transmembrane domains from class I receptor tyrosine kinases. Biochimica et Biophysica Acta (BBA) - Biomembranes 1371:2, pages 199-212.
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Lutz Graeve, Tatjana A. Korolenko, Ulrike Hemmann, Oliver Weiergräber, Elke Dittrich & Peter C. Heinrich. (1996) A complex of the soluble interleukin-6 receptor and interleukin-6 is internalized via the signal transducer gp130. FEBS Letters 399:1-2, pages 131-134.
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