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Molecular and Cellular Biology Volume 16, 1996 - Issue 4
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Research Article

Ku86 Defines the Genetic Defect and Restores X-Ray Resistance and V(D)J Recombination to Complementation Group 5 Hamster Cell Mutants

Abdellatif Errami1 MGC-Department of Radiation Genetics and Chemical Mutagenesis, Leiden University, Leiden, The Netherlands;2 J. A. Cohen Institute, Interuniversity Research Institute for Radiopathology and Radiation Protection, Leiden, The Netherlands
,
Vaughn Smider3 Departments of Medicine and Biochemistry, Stanford University Medical Center, Stanford, California94305
,
W. Kimryn Rathmell3 Departments of Medicine and Biochemistry, Stanford University Medical Center, Stanford, California94305
,
Dong Ming He4 Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island02912
,
Eric A. Hendrickson4 Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island02912
,
Małgorzata Z. Zdzienicka1 MGC-Department of Radiation Genetics and Chemical Mutagenesis, Leiden University, Leiden, The Netherlands;2 J. A. Cohen Institute, Interuniversity Research Institute for Radiopathology and Radiation Protection, Leiden, The NetherlandsCorrespondence[email protected]
&
Gilbert Chu3 Departments of Medicine and Biochemistry, Stanford University Medical Center, Stanford, California94305
 show all
Pages 1519-1526 | Received 01 Nov 1995, Accepted 19 Jan 1996, Published online: 29 Mar 2023

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Noriko Ishida, Tadashi Nakagawa, Shun-Ichiro Iemura, Akira Yasui, Hiroki Shima, Yasutake Katoh, Yuko Nagasawa, Toru Natsume, Kazuhiko Igarashi & Keiko Nakayama. (2017) Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair. Molecular and Cellular Biology 37:4.
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Céline J Rocca, Daniele G Soares, Hana Bouzid, João A P Henriques, Annette K Larsen & Alexandre E Escargueil. (2015) BRCA2 is needed for both repair and cell cycle arrest in mammalian cells exposed to S23906, an anticancer monofunctional DNA binder. Cell Cycle 14:13, pages 2080-2090.
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Han Li, Hannes Vogel, Valerie B. Holcomb, Yansong Gu & Paul Hasty. (2007) Deletion of Ku70, Ku80, or Both Causes Early Aging without Substantially Increased Cancer. Molecular and Cellular Biology 27:23, pages 8205-8214.
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Dae-Sik Lim, Hannes Vogel, Dennis M. Willerford, Arthur T. Sands, Kenneth A. Platt & Paul Hasty. (2000) Analysis of ku80-Mutant Mice and Cells with Deficient Levels of p53. Molecular and Cellular Biology 20:11, pages 3772-3780.
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Renu Tuteja & Narendra Tuteja. (2000) Ku Autoantigen: A Multifunctional DNA-Binding Protein. Critical Reviews in Biochemistry and Molecular Biology 35:1, pages 1-33.
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B. K. Singleton, M. I. Torres-Arzayus, S. T. Rottinghaus, G. E. Taccioli & P. A. Jeggo. (1999) The C Terminus of Ku80 Activates the DNA-Dependent Protein Kinase Catalytic Subunit. Molecular and Cellular Biology 19:5, pages 3267-3277.
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Vaughn Smider, W. Kimryn Rathmell, Greg Brown, Susanna Lewis & Gilbert Chu. (1998) Failure of Hairpin-Ended and Nicked DNA To Activate DNA-Dependent Protein Kinase: Implications for V(D)J Recombination. Molecular and Cellular Biology 18:11, pages 6853-6858.
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Purificación Muñoz, Malgorzata Z. Zdzienicka, Jean-Marie Blanchard & Jacques Piette. (1998) Hypersensitivity of Ku-Deficient Cells toward the DNA Topoisomerase II Inhibitor ICRF-193 Suggests a Novel Role for Ku Antigen during the G2 and M Phases of the Cell Cycle. Molecular and Cellular Biology 18:10, pages 5797-5808.
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Sang Eun Lee, Rachel A. Mitchell, Anthony Cheng & Eric A. Hendrickson. (1997) Evidence for DNA-PK-Dependent and -Independent DNA Double-Strand Break Repair Pathways in Mammalian Cells as a Function of the Cell Cycle. Molecular and Cellular Biology 17:3, pages 1425-1433.
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B. K. Singleton, A. Priestley, H. Steingrimsdottir, D. Gell, T. Blunt, S. P. Jackson, A. R. Lehmann & P. A. Jeggo. (1997) Molecular and Biochemical Characterization of xrs Mutants Defective in Ku80. Molecular and Cellular Biology 17:3, pages 1264-1273.
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Xiantuo Wu & Michael R. Lieber. (1996) Protein-Protein and Protein-DNA Interaction Regions within the DNA End-Binding Protein Ku70-Ku86. Molecular and Cellular Biology 16:9, pages 5186-5193.
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