Citations (97)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (11)
Cullen M. Taniguchi, José O. Aleman, Kohjiro Ueki, Ji Luo, Tomoichiro Asano, Hideaki Kaneto, Gregory Stephanopoulos, Lewis C. Cantley & C. Ronald Kahn. (2007) The p85α Regulatory Subunit of Phosphoinositide 3-Kinase Potentiates c-Jun N-Terminal Kinase-Mediated Insulin Resistance. Molecular and Cellular Biology 27:8, pages 2830-2840.
Read now
Read now
Roger S McIntyre, Joanna K Soczynska, Gary F Lewis, Glenda M MacQueen, Jakub Z Konarski & Sidney H Kennedy. (2006) Managing psychiatric disorders with antidiabetic agents: translational research and treatment opportunities. Expert Opinion on Pharmacotherapy 7:10, pages 1305-1321.
Read now
Read now
Dong Chen, Franck Mauvais-Jarvis, Matthias Bluher, Simon J. Fisher, Alison Jozsi, Laurie J. Goodyear, Kohjiro Ueki & C. Ronald Kahn. (2004) p50α/p55α Phosphoinositide 3-Kinase Knockout Mice Exhibit Enhanced Insulin Sensitivity. Molecular and Cellular Biology 24:1, pages 320-329.
Read now
Read now
Xianmin Xia, Aiwu Cheng, Damilola Akinmade & Anne W. Hamburger. (2003) The N-Terminal 24 Amino Acids of the p55 Gamma Regulatory Subunit of Phosphoinositide 3-Kinase Binds Rb and Induces Cell Cycle Arrest. Molecular and Cellular Biology 23:5, pages 1717-1725.
Read now
Read now
Kohjiro Ueki, David A. Fruman, Saskia M. Brachmann, Yu-Hua Tseng, Lewis C. Cantley & C. Ronald Kahn. (2002) Molecular Balance between the Regulatory and Catalytic Subunits of Phosphoinositide 3-Kinase Regulates Cell Signaling and Survival. Molecular and Cellular Biology 22:3, pages 965-977.
Read now
Read now
Kohjiro Ueki, Petra Algenstaedt, Franck Mauvais-Jarvis & C. Ronald Kahn. (2000) Positive and Negative Regulation of Phosphoinositide 3-Kinase-Dependent Signaling Pathways by Three Different Gene Products of the p85α Regulatory Subunit. Molecular and Cellular Biology 20:21, pages 8035-8046.
Read now
Read now
Pietro Formisano, Francesco Oriente, Francesca Fiory, Matilde Caruso, Claudia Miele, Maria Alessandra Maitan, Francesco Andreozzi, Giovanni Vigliotta, Gerolama Condorelli & Francesco Beguinot. (2000) Insulin-Activated Protein Kinase Cβ Bypasses Ras and Stimulates Mitogen-Activated Protein Kinase Activity and Cell Proliferation in Muscle Cells. Molecular and Cellular Biology 20:17, pages 6323-6333.
Read now
Read now
Margaret A. Lawlor, Xiuhong Feng, Daniel R. Everding, Kerry Sieger, Claire E. H. Stewart & Peter Rotwein. (2000) Dual Control of Muscle Cell Survival by Distinct Growth Factor-Regulated Signaling Pathways. Molecular and Cellular Biology 20:9, pages 3256-3265.
Read now
Read now
Christopher D. Kontos, Thomas P. Stauffer, Wen-Pin Yang, John D. York, Liwen Huang, Michael A. Blanar, Tobias Meyer & Kevin G. Peters. (1998) Tyrosine 1101 of Tie2 Is the Major Site of Association of p85 and Is Required for Activation of Phosphatidylinositol 3-Kinase and Akt. Molecular and Cellular Biology 18:7, pages 4131-4140.
Read now
Read now
Jinghua Yu, Yitao Zhang, James McIlroy, Tamara Rordorf-Nikolic, George A. Orr & Jonathan M. Backer. (1998) Regulation of the p85/p110 Phosphatidylinositol 3′-Kinase: Stabilization and Inhibition of the p110α Catalytic Subunit by the p85 Regulatory Subunit. Molecular and Cellular Biology 18:3, pages 1379-1387.
Read now
Read now
J. Dorrestijn, F. J. van Bussel, J. A. Maasen & D. S. Gomes de Mesquita. (1998) Early Steps in Insulin Action. Archives of Physiology and Biochemistry 106:4, pages 269-289.
Read now
Read now
Articles from other publishers (86)
Timothy A. Donlon, Randi Chen, Kamal H. Masaki, Bradley J. Willcox & Brian J. Morris. (2022) Association with Longevity of Phosphatidylinositol 3-Kinase Regulatory Subunit 1 Gene Variants Stems from Protection against Mortality Risk in Men with Cardiovascular Disease. Gerontology 68:2, pages 162-170.
Crossref
Crossref
Tihitina Y. Aytenfisu, Hannah M. Campbell, Mayukh Chakrabarti, L. Mario Amzel & Sandra B. Gabelli. 2022. PI3K and AKT Isoforms in Immunity. PI3K and AKT Isoforms in Immunity
3
49
.
Raju V.S. Rajala. (2021) Signaling roles of phosphoinositides in the retina. Journal of Lipid Research 62, pages 100041.
Crossref
Crossref
Morris F. White. 2018. Principles of Endocrinology and Hormone Action. Principles of Endocrinology and Hormone Action
121
155
.
Morris F. White. 2017. Textbook of Diabetes. Textbook of Diabetes
114
132
.
Kate L. Weeks, Bianca C. Bernardo, Jenny Y. Y. Ooi, Natalie L. Patterson & Julie R. McMullen. 2017. Exercise for Cardiovascular Disease Prevention and Treatment. Exercise for Cardiovascular Disease Prevention and Treatment
187
210
.
Morris F. White. 2018. Diabetes. Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment. Diabetes. Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment
1
34
.
Morris F. White & Kyle D. Copps. 2016. Endocrinology: Adult and Pediatric. Endocrinology: Adult and Pediatric
556
585.e13
.
Rebecca L. Ross, Julie E. Burns, Claire F. Taylor, Paul Mellor, Deborah H. Anderson & Margaret A. Knowles. (2013) Identification of Mutations in Distinct Regions of p85 Alpha in Urothelial Cancer. PLoS ONE 8:12, pages e84411.
Crossref
Crossref
Johanna Zemva & Markus Schubert. 2013. Metabolic Syndrome and Neurological Disorders. Metabolic Syndrome and Neurological Disorders
31
50
.
Masahiro Shinohara, Masaki Nakamura, Hironari Masuda, Jun Hirose, Yuho Kadono, Mitsuyasu Iwasawa, Yuuichi Nagase, Kohjiro Ueki, Takashi Kadowaki, Takehiko Sasaki, Shigeaki Kato, Hiroaki Nakamura, Sakae Tanaka & Hiroshi Takayanagi. (2012) Class IA phosphatidylinositol 3-kinase regulates osteoclastic bone resorption through protein kinase B-mediated vesicle transport. Journal of Bone and Mineral Research 27:12, pages 2464-2475.
Crossref
Crossref
Susan M.R. Gurney, Peter Forster, Ursula Just & Ralf Schwanbeck. (2011) Suppression of the PI3K subunit p85α delays embryoid body development and inhibits cell adhesion. Journal of Cellular Biochemistry 112:12, pages 3573-3581.
Crossref
Crossref
Jonathon N. Winnay & C. Ronald Kahn. 2011. The Unfolded Protein Response and Cellular Stress, Part B. The Unfolded Protein Response and Cellular Stress, Part B
147
158
.
Cullen M. Taniguchi & C. Ronald Kahn. 2011. Insulin Resistance and Cancer. Insulin Resistance and Cancer
53
76
.
Xuxia Wu & W. Timothy Garvey. 2010. Textbook of Diabetes. Textbook of Diabetes
104
125
.
Raju V.S Rajala. (2010) Phosphoinositide 3-kinase signaling in the vertebrate retina. Journal of Lipid Research 51:1, pages 4-22.
Crossref
Crossref
Kazutaka Aoki, Junji Matsui, Naoto Kubota, Hiromu Nakajima, Keiji Iwamoto, Iseki Takamoto, Youki Tsuji, Akira Ohno, Shuuichi Mori, Kumpei Tokuyama, Koji Murakami, Tomoichiro Asano, Shinichi Aizawa, Kazuyuki Tobe, Takashi Kadowaki & Yasuo Terauchi. (2009)
Role of the liver in glucose homeostasis in PI 3-kinase
p85
α-deficient mice
. American Journal of Physiology-Endocrinology and Metabolism 296:4, pages E842-E853.
Crossref
Crossref
Klaartje Kok, Barbara Geering & Bart Vanhaesebroeck. (2009) Regulation of phosphoinositide 3-kinase expression in health and disease. Trends in Biochemical Sciences 34:3, pages 115-127.
Crossref
Crossref
Michelle R. Jones, Scott G. Wilson, Ben H. Mullin, Robert Mead, Frank Dudbridge, Gerald F. Watts & Bronwyn G.A. Stuckey. (2008) Polymorphism in postinsulin receptor signaling pathway is not associated with polycystic ovary syndrome. Fertility and Sterility 90:6, pages 2298-2303.
Crossref
Crossref
Glenn S. Van Aller, Jeff D. Carson, Christine Fernandes, Ruth Lehr, Robert H. Sinnamon, Robert B. Kirkpatrick, Peter J. Tummino & Lusong Luo. (2008) Characterization of PI3K class IA isoforms with regulatory subunit p55α using a scintillation proximity assay. Analytical Biochemistry 383:2, pages 311-315.
Crossref
Crossref
Yogesh Dwivedi, Hooriyah S Rizavi, Tara Teppen, Hui Zhang, Amal Mondal, Rosalinda C Roberts, Robert R Conley & Ghanshyam N Pandey. (2007) Lower Phosphoinositide 3-Kinase (PI 3-kinase) Activity and Differential Expression Levels of Selective Catalytic and Regulatory PI 3-Kinase Subunit Isoforms in Prefrontal Cortex and Hippocampus of Suicide Subjects. Neuropsychopharmacology 33:10, pages 2324-2340.
Crossref
Crossref
Jan Domin. 2008. EGFR Signaling Networks in Cancer Therapy. EGFR Signaling Networks in Cancer Therapy
91
111
.
Tomoichiro Asano, Midori Fujishiro, Akifumi Kushiyama, Yusuke Nakatsu, Masayasu Yoneda, Hideaki Kamata & Hideyuki Sakoda. (2007) Role of Phosphatidylinositol 3-Kinase Activation on Insulin Action and Its Alteration in Diabetic Conditions. Biological and Pharmaceutical Bulletin 30:9, pages 1610-1616.
Crossref
Crossref
Chad E.N. Reiter, Xiaohua Wu, Lakshman Sandirasegarane, Makoto Nakamura, Kirk A. Gilbert, Ravi S.J. Singh, Patrice E. Fort, David A. Antonetti & Thomas W. Gardner. (2006) Diabetes Reduces Basal Retinal Insulin Receptor Signaling. Diabetes 55:4, pages 1148-1156.
Crossref
Crossref
Marc J. Gunter & Michael F. Leitzmann. (2006) Obesity and colorectal cancer: epidemiology, mechanisms and candidate genes. The Journal of Nutritional Biochemistry 17:3, pages 145-156.
Crossref
Crossref
Cullen M. Taniguchi, Brice Emanuelli & C. Ronald Kahn. (2006) Critical nodes in signalling pathways: insights into insulin action. Nature Reviews Molecular Cell Biology 7:2, pages 85-96.
Crossref
Crossref
Sudha B. Biddinger & C. Ronald Kahn. (2006) FROM MICE TO MEN: Insights into the Insulin Resistance Syndromes. Annual Review of Physiology 68:1, pages 123-158.
Crossref
Crossref
Elena Vigorito & Martin Turner. 2006. Lymphocyte Signal Transduction. Lymphocyte Signal Transduction
43
52
.
Gautam K. Bandyopadhyay, Joseph G. Yu, Jachelle Ofrecio & Jerold M. Olefsky. (2005) Increased p85/55/50 Expression and Decreased Phosphotidylinositol 3-Kinase Activity in Insulin-Resistant Human Skeletal Muscle. Diabetes 54:8, pages 2351-2359.
Crossref
Crossref
A. Lulu Strat, Theresa A. Kokta, Michael V. Dodson, Arieh Gertler, Zida Wu & Rodney A. Hill. (2005) Early signaling interactions between the insulin and leptin pathways in bovine myogenic cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1744:2, pages 164-175.
Crossref
Crossref
Carrie E. McCurdy, Robert T. Davidson & Gregory D. Cartee. (2005) Calorie restriction increases the ratio of phosphatidylinositol 3-kinase catalytic to regulatory subunits in rat skeletal muscle. American Journal of Physiology-Endocrinology and Metabolism 288:5, pages E996-E1001.
Crossref
Crossref
Kathrine Abell, Antonio Bilancio, Richard W. E. Clarkson, Paul G. Tiffen, Anton I. Altaparmakov, Thomas G. Burdon, Tomoichiro Asano, Bart Vanhaesebroeck & Christine J. Watson. (2005) Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition. Nature Cell Biology 7:4, pages 392-398.
Crossref
Crossref
Bart Vanhaesebroeck, Khaled Ali, Antonio Bilancio, Barbara Geering & Lazaros C. Foukas. (2005) Signalling by PI3K isoforms: insights from gene-targeted mice. Trends in Biochemical Sciences 30:4, pages 194-204.
Crossref
Crossref
Mauro Bustamante, Udo Hasler, Olga Kotova, Alexander V. Chibalin, David Mordasini, Martine Rousselot, Alain Vandewalle, Pierre-Yves Martin & Eric Féraille. (2005) Insulin potentiates AVP-induced AQP2 expression in cultured renal collecting duct principal cells. American Journal of Physiology-Renal Physiology 288:2, pages F334-F344.
Crossref
Crossref
Cristina M. Rondinone, Jill Clampit, Rebecca J. Gum, Bradley A. Zinker, Michael R. Jirousek & James M. Trevillyan. (2004) Reduction of PTP1B induces differential expression of PI3-kinase (p85α) isoforms. Biochemical and Biophysical Research Communications 323:2, pages 652-659.
Crossref
Crossref
Christine Y. Christ-Roberts, Thongchai Pratipanawatr, Wilailak Pratipanawatr, Rachele Berria, Renata Belfort, Sangeeta Kashyap & Lawrence J. Mandarino. (2004) Exercise training increases glycogen synthase activity and GLUT4 expression but not insulin signaling in overweight nondiabetic and type 2 diabetic subjects. Metabolism 53:9, pages 1233-1242.
Crossref
Crossref
Kohjiro Ueki, David A. Fruman, Claudine M. Yballe, Mathias Fasshauer, Johannes Klein, Tomoichiro Asano, Lewis C. Cantley & C. Ronald Kahn. (2003) Positive and Negative Roles of p85α and p85β Regulatory Subunits of Phosphoinositide 3-Kinase in Insulin Signaling. Journal of Biological Chemistry 278:48, pages 48453-48466.
Crossref
Crossref
Adam P. Curnock, Yannis Sotsios, Karen L. Wright & Stephen G. Ward. (2003) Optimal Chemotactic Responses of Leukemic T Cells to Stromal Cell-Derived Factor-1 Requires the Activation of Both Class IA and IB Phosphoinositide 3-Kinases. The Journal of Immunology 170:8, pages 4021-4030.
Crossref
Crossref
Daniel Hallmann, Katja Trümper, Heidi Trusheim, Kohjiro Ueki, C. Ronald Kahn, Lewis C. Cantley, David A. Fruman & Dieter Hörsch. (2003) Altered Signaling and Cell Cycle Regulation in Embryonal Stem Cells with a Disruption of the Gene for Phosphoinositide 3-Kinase Regulatory Subunit p85α. Journal of Biological Chemistry 278:7, pages 5099-5108.
Crossref
Crossref
Raju V. S. Rajala, Mark E. McClellan, John D. Ash & Robert E. Anderson. 2003. Retinal Degenerations. Retinal Degenerations
369
376
.
M Jücker, K Südel, S Horn, M Sickel, W Wegner, W Fiedler & RA Feldman. (2002) Expression of a mutated form of the p85α regulatory subunit of phosphatidylinositol 3-kinase in a Hodgkin's lymphoma-derived cell line (CO). Leukemia 16:5, pages 894-901.
Crossref
Crossref
Katrine Almind, Laurent Delahaye, Torben Hansen, Emmanuel Van Obberghen, Oluf Pedersen & C. Ronald Kahn. (2002) Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85α. Proceedings of the National Academy of Sciences 99:4, pages 2124-2128.
Crossref
Crossref
Kohjiro Ueki, Claudine M. Yballe, Saskia M. Brachmann, David Vicent, John M. Watt, C. Ronald Kahn & Lewis C. Cantley. (2001) Increased insulin sensitivity in mice lacking p85β subunit of phosphoinositide 3-kinase. Proceedings of the National Academy of Sciences 99:1, pages 419-424.
Crossref
Crossref
Franck Mauvais-Jarvis, Kohjiro Ueki, David A. Fruman, Michael F. Hirshman, Kei Sakamoto, Laurie J. Goodyear, Matteo Iannacone, Domenico Accili, Lewis C. Cantley & C. Ronald Kahn. (2002) Reduced expression of the murine p85α subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes. Journal of Clinical Investigation 109:1, pages 141-149.
Crossref
Crossref
Franck Mauvais-Jarvis, Kohjiro Ueki, David A. Fruman, Michael F. Hirshman, Kei Sakamoto, Laurie J. Goodyear, Matteo Iannacone, Domenico Accili, Lewis C. Cantley & C. Ronald Kahn. (2002) Reduced expression of the murine p85α subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes. Journal of Clinical Investigation 109:1, pages 141-149.
Crossref
Crossref
Franck Mauvais-Jarvis, Kohjiro Ueki, David A. Fruman, Michael F. Hirshman, Kei Sakamoto, Laurie J. Goodyear, Matteo Iannacone, Domenico Accili, Lewis C. Cantley & C. Ronald Kahn. (2002) Reduced expression of the murine p85α subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes. Journal of Clinical Investigation 109:1, pages 141-149.
Crossref
Crossref
Alan R. Saltiel & C. Ronald Kahn. (2001) Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414:6865, pages 799-806.
Crossref
Crossref
Amira Klip & Andre Marette. 2011. Comprehensive Physiology. Comprehensive Physiology
451
494
.
Kouichi Inukai, Makoto Funaki, Motonobu Anai, Takehide Ogihara, Hideki Katagiri, Yasushi Fukushima, Hideyuki Sakoda, Yukiko Onishi, Hiraku Ono, Midori Fujishiro, Miho Abe, Yoshitomo Oka, Masatoshi Kikuchi & Tomoichiro Asano. (2001) Five isoforms of the phosphatidylinositol 3-kinase regulatory subunit exhibit different associations with receptor tyrosine kinases and their tyrosine phosphorylations. FEBS Letters 490:1-2, pages 32-38.
Crossref
Crossref
Alexandra Kessler, Ingo Uphues, D. Margriet Ouwens, Martin Till & Jürgen Eckel. (2001) Diversification of cardiac insulin signaling involves the p85α/β subunits of phosphatidylinositol 3-kinase. American Journal of Physiology-Endocrinology and Metabolism 280:1, pages E65-E74.
Crossref
Crossref
David A. Fruman, Franck Mauvais-Jarvis, Daniel A. Pollard, Claudine M. Yballe, Derek Brazil, Roderick T. Bronson, C. Ronald Kahn & Lewis C. Cantley. (2000) Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85α. Nature Genetics 26:3, pages 379-382.
Crossref
Crossref
Tomoichiro Asano, Akira Kanda, Hideki Katagiri, Masao Nawano, Takehide Ogihara, Kouichi Inukai, Motonobu Anai, Yasushi Fukushima, Yoshio Yazaki, Masatoshi Kikuchi, Roya Hooshmand-Rad, Carl-Henrik Heldin, Yoshitomo Oka & Makoto Funaki. (2000) p110β Is Up-regulated during Differentiation of 3T3-L1 Cells and Contributes to the Highly Insulin-responsive Glucose Transport Activity. Journal of Biological Chemistry 275:23, pages 17671-17676.
Crossref
Crossref
Makoto Funaki, Hideki Katagiri, Kouichi Inukai, Masotoshi Kikuchi & Tomoichiro Asano. (2000) Structure and function of phosphatidylinositol-3,4 kinase. Cellular Signalling 12:3, pages 135-142.
Crossref
Crossref
R. Hooshmand-RadL. HajkovaP. KlintR. KarlssonB. VanhaesebroeckL. Claesson-WelshC.H. Heldin. (2000) The PI 3-kinase isoforms p110(alpha) and p110(beta) have differential roles in PDGF- and insulin-mediated signaling. Journal of Cell Science 113:2, pages 207-214.
Crossref
Crossref
Dieter H�rsch & C. Ronald Kahn. (1999) Region-specific mRNA expression of phosphatidylinositol 3-kinase regulatory isoforms in the central nervous system of C57BL/6J mice. The Journal of Comparative Neurology 415:1, pages 105-120.
Crossref
Crossref
Ibrahim A. Aksoy, Marilyn J. Ramsey, David A. Fruman, Saime Aksoy, Lewis C. Cantley, James D. Tucker & Thomas M. Roberts. (1999) Mouse Phosphoinositide 3-Kinase p110α Gene: Cloning, Structural Organization, and Localization to Chromosome 3 Band B. Biochemical and Biophysical Research Communications 262:2, pages 438-442.
Crossref
Crossref
Tung O. ChanSusan E. RittenhousePhilip N. Tsichlis. (1999) AKT/PKB and Other D3 Phosphoinositide-Regulated Kinases: Kinase Activation by Phosphoinositide-Dependent Phosphorylation. Annual Review of Biochemistry 68:1, pages 965-1014.
Crossref
Crossref
Caroline A Beeton, Pam Das, Michael D Waterfield & Peter R Shepherd. (1999) The SH3 and BH Domains of the p85α Adapter Subunit Play a Critical Role in Regulating Class Ia Phosphoinositide 3-Kinase Function. Molecular Cell Biology Research Communications 1:2, pages 153-157.
Crossref
Crossref
Antti Virkamäki, Kohjiro Ueki & C. Ronald Kahn. (1999) Protein–protein interaction in insulin signaling and the molecular mechanisms of insulin resistance. Journal of Clinical Investigation 103:7, pages 931-943.
Crossref
Crossref
Ailsa G. Harpur, Meredith J. Layton, Pamela Das, Matthew J. Bottomley, George Panayotou, Paul C. Driscoll & Michael D. Waterfield. (1999) Intermolecular Interactions of the p85α Regulatory Subunit of Phosphatidylinositol 3-Kinase. Journal of Biological Chemistry 274:18, pages 12323-12332.
Crossref
Crossref
Maria Luiza de L.A. Fernandes, Mário J.A Saad & Lı́cio A Velloso. (1999) Insulin induces tyrosine phosphorylation of the insulin receptor and SHC, and SHC/GRB2 association in cerebellum but not in forebrain cortex of rats. Brain Research 826:1, pages 74-82.
Crossref
Crossref
Yasuo Terauchi, Youki Tsuji, Shinobu Satoh, Hideaki Minoura, Koji Murakami, Akira Okuno, Kouichi Inukai, Tomoichiro Asano, Yasushi Kaburagi, Kohjiro Ueki, Hiromu Nakajima, Toshiaki Hanafusa, Yuji Matsuzawa, Hisahiko Sekihara, Yuxin Yin, J. Carl Barrett, Hideaki Oda, Takatoshi Ishikawa, Yasuo Akanuma, Issei Komuro, Misao Suzuki, Ken-ichi Yamamura, Tatsuhiko Kodama, Harumi Suzuki, Shigeo Koyasu, Shinichi Aizawa, Kazuyuki Tobe, Yasuhisa Fukui, Yoshio Yazaki & Takashi Kadowaki. (1999) Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3–kinase. Nature Genetics 21:2, pages 230-235.
Crossref
Crossref
David A. FrumanScott B. SnapperClaudine M. YballeLaurie DavidsonJonathan Y. YuFrederick W. AltLewis C. Cantley. (1999) Impaired B Cell Development and Proliferation in Absence of Phosphoinositide 3-Kinase p85α. Science 283:5400, pages 393-397.
Crossref
Crossref
Harumi SuzukiYasuo TerauchiMari FujiwaraShinichi AizawaYoshio YazakiTakashi KadowakiShigeo Koyasu. (1999)
Xid
-Like Immunodeficiency in Mice with Disruption of the p85α Subunit of Phosphoinositide 3-Kinase
. Science 283:5400, pages 390-392.
Crossref
Crossref
Jean-Pierre Després & André Marette. 1999. Insulin Resistance. Insulin Resistance
51
81
.
Matthias P Wymann & Luciano Pirola. (1998) Structure and function of phosphoinositide 3-kinases. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1436:1-2, pages 127-150.
Crossref
Crossref
Yong-Jiang Hei. (1998) Recent progress in insulin signal transduction. Journal of Pharmacological and Toxicological Methods 40:3, pages 123-135.
Crossref
Crossref
David A. FrumanRachel E. MeyersLewis C. Cantley. (1998) PHOSPHOINOSITIDE KINASES. Annual Review of Biochemistry 67:1, pages 481-507.
Crossref
Crossref
Gen Inoue, Bentley Cheatham, Renee Emkey & C. Ronald Kahn. (1998) Dynamics of Insulin Signaling in 3T3-L1 Adipocytes. Journal of Biological Chemistry 273:19, pages 11548-11555.
Crossref
Crossref
Bhakta R Dey, Richard W Furlanetto & S.Peter Nissley. (1998) Cloning of human p55γ, a regulatory subunit of phosphatidylinositol 3-kinase, by a yeast two-hybrid library screen with the insulin-like growth factor-I receptor. Gene 209:1-2, pages 175-183.
Crossref
Crossref
Perla Kaliman, Judith Canicio, Peter R. Shepherd, Carolyn A. Beeton, Xavier Testar, Manuel Palacín & Antonio Zorzano. (1998) Insulin-like Growth Factors Require Phosphatidylinositol 3-Kinase to Signal Myogenesis: Dominant Negative p85 Expression Blocks Differentiation of L6E9 Muscle Cells. Molecular Endocrinology 12:1, pages 66-77.
Crossref
Crossref
Jeffrey A. Greenwood, Manuel A. Pallero, Anne B. Theibert & Joanne E. Murphy-Ullrich. (1998) Thrombospondin Signaling of Focal Adhesion Disassembly Requires Activation of Phosphoinositide 3-Kinase. Journal of Biological Chemistry 273:3, pages 1755-1763.
Crossref
Crossref
Elizabeth A. Ottinger, Martyn C. Botfield & Steven E. Shoelson. (1998) Tandem SH2 Domains Confer High Specificity in Tyrosine Kinase Signaling. Journal of Biological Chemistry 273:2, pages 729-735.
Crossref
Crossref
David K. Moscatello, Marina Holgado-Madruga, David R. Emlet, R. Bruce Montgomery & Albert J. Wong. (1998) Constitutive Activation of Phosphatidylinositol 3-Kinase by a Naturally Occurring Mutant Epidermal Growth Factor Receptor. Journal of Biological Chemistry 273:1, pages 200-206.
Crossref
Crossref
M. F. White & L. Yenush. 1998. Protein Modules in Signal Transduction. Protein Modules in Signal Transduction
179
208
.
Morris F. White. 1998. Insulin Action. Insulin Action
3
11
.
Isabelle Mothe, Laurent Delahaye, Chantal Filloux, Sebastian Pons, Morris F. White & Emmanuel Van Obberghen. (1997) Interaction of Wild Type and Dominant-Negative p55PIK Regulatory Subunit of Phosphatidylinositol 3-Kinase with Insulin-Like Growth Factor-1 Signaling Proteins. Molecular Endocrinology 11:13, pages 1911-1923.
Crossref
Crossref
Takehide Ogihara, Toshiaki Isobe, Tohru Ichimura, Masato Taoka, Makoto Funaki, Hideyuki Sakoda, Yukiko Onishi, Kouichi Inukai, Motonobu Anai, Yasushi Fukushima, Masatoshi Kikuchi, Yoshio Yazaki, Yoshitomo Oka & Tomoichiro Asano. (1997) 14-3-3 Protein Binds to Insulin Receptor Substrate-1, One of the Binding Sites of Which Is in the Phosphotyrosine Binding Domain. Journal of Biological Chemistry 272:40, pages 25267-25274.
Crossref
Crossref
Petra Algenstaedt, David A. Antonetti, Michael B. Yaffe & C. Ronald Kahn. (1997) Insulin Receptor Substrate Proteins Create a Link between the Tyrosine Phosphorylation Cascade and the Ca2+-ATPases in Muscle and Heart. Journal of Biological Chemistry 272:38, pages 23696-23702.
Crossref
Crossref
Paulos Berhanu, Celia Anderson, Matt Hickman & Theodore P. Ciaraldi. (1997) Insulin Signal Transduction by a Mutant Human Insulin Receptor Lacking the NPEY Sequence. Journal of Biological Chemistry 272:36, pages 22884-22890.
Crossref
Crossref
Peter R. Shepherd, Barbara T. Navé, Jorge Rincon, Lorraine A. Nolte, A. Paul Bevan, Kenneth Siddle, Juleen R. Zierath & Harriet Wallberg-Henriksson. (1997) Differential Regulation of Phosphoinositide 3-Kinase Adapter Subunit Variants by Insulin in Human Skeletal Muscle. Journal of Biological Chemistry 272:30, pages 19000-19007.
Crossref
Crossref
J. Domin & M.D. Waterfield. (1997) Using structure to define the function of phosphoinositide 3-kinase family members. FEBS Letters 410:1, pages 91-95.
Crossref
Crossref
David Weinkove, Sally J. Leevers, Lindsay K. MacDougall & Michael D. Waterfield. (1997) p60 Is an Adaptor for the DrosophilaPhosphoinositide 3-Kinase, Dp110. Journal of Biological Chemistry 272:23, pages 14606-14610.
Crossref
Crossref
Kouichi Inukai, Makoto Funaki, Takehide Ogihara, Hideki Katagiri, Akira Kanda, Motonobu Anai, Yasushi Fukushima, Toshio Hosaka, Masakazu Suzuki, Bo-Chul Shin, Kuniaki Takata, Yoshio Yazaki, Masatoshi Kikuchi, Yoshitomo Oka & Tomoichiro Asano. (1997) p85α Gene Generates Three Isoforms of Regulatory Subunit for Phosphatidylinositol 3-Kinase (PI 3-Kinase), p50α, p55α, and p85α, with Different PI 3-Kinase Activity Elevating Responses to Insulin. Journal of Biological Chemistry 272:12, pages 7873-7882.
Crossref
Crossref
A. Eguinoa, S. Krugmann, J. Coadwell, L. Stephens & P. Hawkins. 1997. Molecular Mechanisms of Signalling and Membrane Transport. Molecular Mechanisms of Signalling and Membrane Transport
175
188
.
A Chattopadhyay, H.L. James & D.S. Fair. (1992) Molecular recognition sites on factor Xa which participate in the prothrombinase complex.. Journal of Biological Chemistry 267:17, pages 12323-12329.
Crossref
Crossref