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Research Article

Differentiation-Dependent Expression of the Brown Adipocyte Uncoupling Protein Gene: Regulation by Peroxisome Proliferator-Activated Receptor γ

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Pages 3410-3419 | Received 20 Oct 1995, Accepted 04 Apr 1996, Published online: 29 Mar 2023

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Crossref
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Francesc Villarroya, Marion Peyrou & Marta Giralt. (2017) Transcriptional regulation of the uncoupling protein-1 gene. Biochimie 134, pages 86-92.
Crossref
Laura J. den Hartigh, Shari Wang, Leela Goodspeed, Tomasz Wietecha, Barbara Houston, Mohamed Omer, Kayoko Ogimoto, Savitha Subramanian, G. A. Nagana Gowda, Kevin D. O’Brien, Karl J. Kaiyala, Gregory J. Morton & Alan Chait. (2017) Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice. PLOS ONE 12:2, pages e0172912.
Crossref
Wouter D. van Marken Lichtenbelt & Emmani B. M. Nascimento. 2017. Adipose Tissue Biology. Adipose Tissue Biology 301 317 .
Tao Nie, Xiaoyan Hui, Liufeng Mao, Baoming Nie, Kuai Li, Wei Sun, Xuefei Gao, Xiaofeng Tang, Yong Xu, Baishan Jiang, Zhengcao Tu, Peng Li, Ke Ding, Weiping Han, Shaoping Zhang, Aimin Xu, Sheng Ding, Pentao Liu, Adam Patterson, Garth Cooper & Donghai Wu. (2016) Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis. Scientific Reports 6:1.
Crossref
M Cairó, J Villarroya, R Cereijo, L Campderrós, M Giralt & F Villarroya. (2016) Thermogenic activation represses autophagy in brown adipose tissue. International Journal of Obesity 40:10, pages 1591-1599.
Crossref
Takeshi Inagaki, Juro Sakai & Shingo Kajimura. (2016) Transcriptional and epigenetic control of brown and beige adipose cell fate and function. Nature Reviews Molecular Cell Biology 17:8, pages 480-495.
Crossref
Marta Giralt, Montserrat Cairó & Francesc Villarroya. (2016) Hormonal and nutritional signalling in the control of brown and beige adipose tissue activation and recruitment. Best Practice & Research Clinical Endocrinology & Metabolism 30:4, pages 515-525.
Crossref
Congcong Wang, Xianglu Zeng, Zhaocai Zhou, Jian Zhao & Gang Pei. (2016) β-arrestin-1 contributes to brown fat function and directly interacts with PPARα and PPARγ. Scientific Reports 6:1.
Crossref
Hong Guo, Rocio Foncea, Sheila M. O'Byrne, Hongfeng Jiang, Yuanyuan Zhang, Jessica A. Deis, William S. Blaner, David A. Bernlohr & Xiaoli Chen. (2016) Lipocalin 2, a Regulator of Retinoid Homeostasis and Retinoid-mediated Thermogenic Activation in Adipose Tissue. Journal of Biological Chemistry 291:21, pages 11216-11229.
Crossref
Ramesh Pothuraju, Raj Kumar Sharma, Suneel Kumar Onteru, Satvinder Singh & Shaik Abdul Hussain. (2016) Hypoglycemic and Hypolipidemic Effects of Aloe vera Extract Preparations: A Review . Phytotherapy Research 30:2, pages 200-207.
Crossref
Soonkyu Chung, Young Jun Kim, Soo Jin Yang, Yunkyoung Lee & Myoungsook Lee. (2016) Nutrigenomic Functions of PPARs in Obesogenic Environments. PPAR Research 2016, pages 1-17.
Crossref
M. Luisa Bonet, Jose A. Canas, Joan Ribot & Andreu Palou. 2016. Carotenoids in Nature. Carotenoids in Nature 377 414 .
Larissa G. P. Langhi, Leonardo R. Andrade, Marilia Kimie Shimabukuro, Willem van Ewijk, Dennis D. Taub, Radovan Borojevic & Valeria de Mello Coelho. (2015) Lipid-Laden Multilocular Cells in the Aging Thymus Are Phenotypically Heterogeneous. PLOS ONE 10:10, pages e0141516.
Crossref
Y Xu, S Miriyala, F Fang, V Bakthavatchalu, T Noel, D M Schell, C Wang, W H St Clair & D K St Clair. (2014) Manganese superoxide dismutase deficiency triggers mitochondrial uncoupling and the Warburg effect. Oncogene 34:32, pages 4229-4237.
Crossref
Aleksandra Jankovic, Igor Golic, Milica Markelic, Ana Stancic, Vesna Otasevic, Biljana Buzadzic, Aleksandra Korac & Bato Korac. (2015) Two key temporally distinguishable molecular and cellular components of white adipose tissue browning during cold acclimation. The Journal of Physiology 593:15, pages 3267-3280.
Crossref
Patrick Seale. (2015) Transcriptional Regulatory Circuits Controlling Brown Fat Development and Activation. Diabetes 64:7, pages 2369-2375.
Crossref
Jianfei Fu, Zhen Li, Huiqin Zhang, Yushan Mao, Anshi Wang, Xin Wang, Zuquan Zou & Xiaohong Zhang. (2015) Molecular pathways regulating the formation of brown-like adipocytes in white adipose tissue. Diabetes/Metabolism Research and Reviews 31:5, pages 433-452.
Crossref
Tamiris Lima Rachid, Aline Penna-de-Carvalho, Isabele Bringhenti, Marcia Barbosa Aguila, Carlos Alberto Mandarim-de-Lacerda & Vanessa Souza-Mello. (2015) PPAR-α agonist elicits metabolically active brown adipocytes and weight loss in diet-induced obese mice. Cell Biochemistry and Function 33:4, pages 249-256.
Crossref
Timothy Hardy, Quentin M. Anstee & Christopher P. Day. (2015) Nonalcoholic fatty liver disease. Current Opinion in Gastroenterology 31:3, pages 175-183.
Crossref
Satoshi Iida, Wei Chen, Tomoyoshi Nakadai, Yoshiaki Ohkuma & Robert G. Roeder. (2015) PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1 . Genes & Development 29:3, pages 308-321.
Crossref
Anne Loft, Søren Fisker Schmidt & Susanne Mandrup. (2015) Modulating the Genomic Programming of Adipocytes. Cold Spring Harbor Symposia on Quantitative Biology 80, pages 239-248.
Crossref
Anne Loft, Isabel Forss, Majken Storm Siersbæk, Søren Fisker Schmidt, Ann-Sofie Bøgh Larsen, Jesper Grud Skat Madsen, Didier F. Pisani, Ronni Nielsen, Mads Malik Aagaard, Angela Mathison, Matt J. Neville, Raul Urrutia, Fredrik Karpe, Ez-Zoubir Amri & Susanne Mandrup. (2015) Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers. Genes & Development 29:1, pages 7-22.
Crossref
Andrea Galmozzi, Si B. Sonne, Svetlana Altshuler-Keylin, Yutaka Hasegawa, Kosaku Shinoda, Ineke H.N. Luijten, Jae Won Chang, Louis Z. Sharp, Benjamin F. Cravatt, Enrique Saez & Shingo Kajimura. (2014) ThermoMouse: An In Vivo Model to Identify Modulators of UCP1 Expression in Brown Adipose Tissue. Cell Reports 9:5, pages 1584-1593.
Crossref
Limei Wang, Birgit Waltenberger, Eva-Maria Pferschy-Wenzig, Martina Blunder, Xin Liu, Clemens Malainer, Tina Blazevic, Stefan Schwaiger, Judith M. Rollinger, Elke H. Heiss, Daniela Schuster, Brigitte Kopp, Rudolf Bauer, Hermann Stuppner, Verena M. Dirsch & Atanas G. Atanasov. (2014) Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review. Biochemical Pharmacology 92:1, pages 73-89.
Crossref
Nai-sheng LU, Gang SHU, Qiu-ping XIE, Xiao-tong ZHU, Ping GAO, Gui-xuan ZHOU, Songbo WANG, Li-na WANG, Qian-yun XI, Yong-liang ZHANG & Qing-yan JIANG. (2014) Myristic Acid (MA) Promotes Adipogenic Gene Expression and the Differentiation of Porcine Intramuscular Adipocyte Precursor Cells. Journal of Integrative Agriculture 13:11, pages 2488-2499.
Crossref
Dinh-Toi Chu, Elzbieta Malinowska, Barbara Gawronska-Kozak & Leslie P. Kozak. (2014) Expression of Adipocyte Biomarkers in a Primary Cell Culture Models Reflects Preweaning Adipobiology. Journal of Biological Chemistry 289:26, pages 18478-18488.
Crossref
Bethany P Cummings, Ahmed Bettaieb, James L Graham, Kimber Stanhope, Fawaz G Haj & Peter J Havel. (2014) Administration of pioglitazone alone or with alogliptin delays diabetes onset in UCD-T2DM rats. Journal of Endocrinology 221:1, pages 133-144.
Crossref
Ramesh Pothuraju, Raj Kumar Sharma, Jayasimha Chagalamarri, Surender Jangra & Praveen Kumar Kavadi. (2014) A systematic review of Gymnema sylvestre in obesity and diabetes management . Journal of the Science of Food and Agriculture 94:5, pages 834-840.
Crossref
Yoshinori Hiraoka, Tatsuhiko Matsuoka, Mikiko Ohno, Kazuhiro Nakamura, Sayaka Saijo, Shigenobu Matsumura, Kiyoto Nishi, Jiro Sakamoto, Po-Min Chen, Kazuo Inoue, Tohru Fushiki, Toru Kita, Takeshi Kimura & Eiichiro Nishi. (2014) Critical roles of nardilysin in the maintenance of body temperature homoeostasis. Nature Communications 5:1.
Crossref
Daekeun Kwon, Junyong Kang, Jaeseung Kim & Youngju Song. (2014) Opuntia humifusa Supplementation Reduces Fat Weight by Increasing PPAR-γ and PGC-1α Protein Expression in the Skeletal Muscle of Rats. Journal of Life Science 24:1, pages 67-73.
Crossref
Maria Murholm, Marie S Isidor, Astrid L Basse, Sally Winther, Cathrine Sørensen, Jonas Skovgaard-Petersen, Maja M Nielsen, Aina S Hansen, Bjørn Quistorff & Jacob B Hansen. (2013) Retinoic acid has different effects on UCP1 expression in mouse and human adipocytes. BMC Cell Biology 14:1.
Crossref
Paul LeeMichael M. Swarbrick & Ken K. Y. Ho. (2013) Brown Adipose Tissue in Adult Humans: A Metabolic Renaissance. Endocrine Reviews 34:3, pages 413-438.
Crossref
Pavel Flachs, Martin Rossmeisl, Ondrej Kuda & Jan Kopecky. (2013) Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: A key to lean phenotype. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1831:5, pages 986-1003.
Crossref
M. Luisa Bonet, Paula Oliver & Andreu Palou. (2013) Pharmacological and nutritional agents promoting browning of white adipose tissue. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1831:5, pages 969-985.
Crossref
. 2013. Bioenergetics. Bioenergetics 387 406 .
Ji Suk Chang, Vivian Fernand, Yubin Zhang, Jeho Shin, Hee-Jin Jun, Yagini Joshi & Thomas W. Gettys. (2012) NT-PGC-1α Protein Is Sufficient to Link β3-Adrenergic Receptor Activation to Transcriptional and Physiological Components of Adaptive Thermogenesis. Journal of Biological Chemistry 287:12, pages 9100-9111.
Crossref
Haruya Ohno, Kosaku Shinoda, Bruce M. Spiegelman & Shingo Kajimura. (2012) PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein. Cell Metabolism 15:3, pages 395-404.
Crossref
M. Luisa Bonet, Joan Ribot & Andreu Palou. (2012) Lipid metabolism in mammalian tissues and its control by retinoic acid. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1821:1, pages 177-189.
Crossref
Julien Delezie & Etienne Challet. (2011) Interactions between metabolism and circadian clocks: reciprocal disturbances. Annals of the New York Academy of Sciences 1243:1, pages 30-46.
Crossref
Elayne Hondares, Meritxell Rosell, Julieta Díaz-Delfín, Yolanda Olmos, Maria Monsalve, Roser Iglesias, Francesc Villarroya & Marta Giralt. (2011) Peroxisome Proliferator-activated Receptor α (PPARα) Induces PPARγ Coactivator 1α (PGC-1α) Gene Expression and Contributes to Thermogenic Activation of Brown Fat. Journal of Biological Chemistry 286:50, pages 43112-43122.
Crossref
Xuan Yao, Shifang Shan, Ying Zhang & Hao Ying. (2011) Recent progress in the study of brown adipose tissue. Cell & Bioscience 1:1.
Crossref
Enrico Campioli, Gianluca Carnevale, Rossella Avallone, Deanna Guerra & Mario Baraldi. (2011) Morphological and Receptorial Changes in the Epididymal Adipose Tissue of Rats Subjected to a Stressful Stimulus. Obesity 19:4, pages 703-708.
Crossref
Arturo Hernandez, Raquel Martinez de Mena, Eva Martin & Maria-Jesus Obregon. (2011) Differences in the Response of UCP1 mRNA to Hormonal Stimulation Between Rat and Mouse Primary Cultures of Brown Adipocytes. Cellular Physiology and Biochemistry 28:5, pages 969-980.
Crossref
Rachel Conyers, Sophie Young & David M. Thomas. (2011) Liposarcoma: Molecular Genetics and Therapeutics. Sarcoma 2011, pages 1-13.
Crossref
Vesna Petrović, Biljana Buzadžić, Aleksandra Korać, Ana Vasilijević, Aleksandra Janković & Bato Korać. (2010) NO modulates the molecular basis of rat interscapular brown adipose tissue thermogenesis. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 152:2, pages 147-159.
Crossref
Sakthi Baby GayathriB.Tech.B.Tech., Venkatesan RadhaM.Sc., Ph.M.Sc., Ph., Karani S. VimaleswaranM.Sc., Ph.M.Sc., Ph. & Viswanathan MohanM.D., Ph.DM.D., Ph.D. (2010) Association of the PPARGC1A Gene Polymorphism With Diabetic Nephropathy in an Asian Indian Population (CURES-41) . Metabolic Syndrome and Related Disorders 8:2, pages 119-126.
Crossref
Soledad Miranda, Águeda González-Rodríguez, Jesús Revuelta-Cervantes, Cristina M. Rondinone & Ángela M. Valverde. (2010) Beneficial effects of PTP1B deficiency on brown adipocyte differentiation and protection against apoptosis induced by pro- and anti-inflammatory stimuli. Cellular Signalling 22:4, pages 645-659.
Crossref
Ursula A. White & Jacqueline M. Stephens. 2010. Adipose Tissue in Health and Disease. Adipose Tissue in Health and Disease 1 20 .
Leslie P. Kozak & Robert A. Koza. 2010. Genes and Obesity. Genes and Obesity 75 123 .
Samuel M. Cohen, Richard D. Storer, Kay A. Criswell, Nancy G. Doerrer, Vicki L. Dellarco, David G. Pegg, Zbigniew W. Wojcinski, David E. Malarkey, Abigail C. Jacobs, James E. Klaunig, James A. Swenberg & Jon C. Cook. (2009) Hemangiosarcoma in Rodents: Mode-of-Action Evaluation and Human Relevance. Toxicological Sciences 111:1, pages 4-18.
Crossref
Wei Chen, Qiheng Yang & Robert G. Roeder. (2009) Dynamic Interactions and Cooperative Functions of PGC-1α and MED1 in TRα-Mediated Activation of the Brown-Fat-Specific UCP-1 Gene. Molecular Cell 35:6, pages 755-768.
Crossref
Harumi Uto-Kondo, Reiko Ohmori, Chikako Kiyose, Yoshimi Kishimoto, Hisako Saito, Osamu Igarashi & Kazuo Kondo. (2009) Tocotrienol Suppresses Adipocyte Differentiation and Akt Phosphorylation in 3T3-L1 Preadipocytes. The Journal of Nutrition 139:1, pages 51-57.
Crossref
L P Kozak & R Anunciado-Koza. (2009) UCP1: its involvement and utility in obesity. International Journal of Obesity 32:S7, pages S32-S38.
Crossref
임영조, Park,Sung-Han, Lee Jong-Sam, Jangkyu Lee, Hee-won Moon & JungKyu Kim. (2008) The influence of dietary feeding type and acute exercise on gene expression of PPAR isoforms in skeletal muscle. Exercise Science 17:4, pages 401-412.
Crossref
Andrew W. Norris, Michael F. Hirshman, Jianrong Yao, Niels Jessen, Nicolas Musi, Lihong Chen, William I. Sivitz, Laurie J. Goodyear & C. Ronald Kahn. (2008) Endogenous Peroxisome Proliferator-Activated Receptor-γ Augments Fatty Acid Uptake in Oxidative Muscle. Endocrinology 149:11, pages 5374-5383.
Crossref
T. Varga & L. Nagy. (2008) Nuclear receptors, transcription factors linking lipid metabolism and immunity: the case of peroxisome proliferator-activated receptor gamma. European Journal of Clinical Investigation 38:10, pages 695-707.
Crossref
Peter TontonozBruce M. Spiegelman. (2008) Fat and Beyond: The Diverse Biology of PPARγ. Annual Review of Biochemistry 77:1, pages 289-312.
Crossref
Masahiro Watanabe, Takenori Yamamoto, Chihiro Mori, Naoto Okada, Naoshi Yamazaki, Kazuaki Kajimoto, Masatoshi KataokaYasuo Shinohara. (2008) Cold-Induced Changes in Gene Expression in Brown Adipose Tissue: Implications for the Activation of Thermogenesis. Biological and Pharmaceutical Bulletin 31:5, pages 775-784.
Crossref
Alistair VW Nunn, Jimmy Bell & Philip Barter. (2007) The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance. Nuclear Receptor 5:1.
Crossref
Johanna A. Jörgensen, Damir Zadravec & Anders Jacobsson. (2007) Norepinephrine and rosiglitazone synergistically induce Elovl3 expression in brown adipocytes . American Journal of Physiology-Endocrinology and Metabolism 293:5, pages E1159-E1168.
Crossref
Darja Debevec, Mark Christian, Daniel Morganstein, Asha Seth, Birger Herzog, Malcolm Parker & Roger White. (2007) Receptor Interacting Protein 140 Regulates Expression of Uncoupling Protein 1 in Adipocytes through Specific Peroxisome Proliferator Activated Receptor Isoforms and Estrogen-Related Receptor α. Molecular Endocrinology 21:7, pages 1581-1592.
Crossref
K.S. Vimaleswaran, V. Radha, R. Deepa & V. Mohan. (2007) Absence of Association of Metabolic Syndrome with PPARGC1A, PPARG and UCP1 Gene Polymorphisms in Asian Indians. Metabolic Syndrome and Related Disorders 5:2, pages 153-162.
Crossref
Francesc Villarroya, Roser Iglesias & Marta Giralt. (2007) PPARs in the Control of Uncoupling Proteins Gene Expression. PPAR Research 2007, pages 1-12.
Crossref
S. Rodríguez-Cuenca, M. Monjo, M. Gianotti, A. M. Proenza & P. Roca. (2007) Expression of mitochondrial biogenesis-signaling factors in brown adipocytes is influenced specifically by 17β-estradiol, testosterone, and progesterone. American Journal of Physiology-Endocrinology and Metabolism 292:1, pages E340-E346.
Crossref
Huiyun Liang & Walter F. Ward. (2006) PGC-1α: a key regulator of energy metabolism. Advances in Physiology Education 30:4, pages 145-151.
Crossref
Liliane Michalik, Johan Auwerx, Joel P. Berger, V. Krishna Chatterjee, Christopher K. Glass, Frank J. Gonzalez, Paul A. Grimaldi, Takashi Kadowaki, Mitchell A. Lazar, Stephen O'Rahilly, Colin N. A. Palmer, Jorge Plutzky, Janardan K. Reddy, Bruce M. Spiegelman, Bart Staels & Walter Wahli. (2006) International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors. Pharmacological Reviews 58:4, pages 726-741.
Crossref
Adrian T. Coyle & B. Therese Kinsella. (2006) Synthetic peroxisome proliferator-activated receptor γ agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells. Biochemical Pharmacology 71:9, pages 1308-1323.
Crossref
Sylvie Franckhauser, Sergio Muñoz, Ivet Elias, Tura Ferre & Fatima Bosch. (2006) Adipose Overexpression of Phospho enol pyruvate Carboxykinase Leads to High Susceptibility to Diet-Induced Insulin Resistance and Obesity . Diabetes 55:2, pages 273-280.
Crossref
Timo Kanzleiter, Tatjana Schneider, Isabel Walter, Florian Bolze, Christoph Eickhorst, Gerhard Heldmaier, Susanne Klaus & Martin Klingenspor. (2006) Evidence for Nr4a1 as a cold-induced effector of brown fat thermogenesis. Physiological Genomics 24:1, pages 37-44.
Crossref
Olivia S. Gardner, Brian J. Dewar & Lee M. Graves. (2005) Activation of Mitogen-Activated Protein Kinases by Peroxisome Proliferator-Activated Receptor Ligands: An Example of Nongenomic Signaling. Molecular Pharmacology 68:4, pages 933-941.
Crossref
Alison Sharpe Avram, Mathew M. Avram & William D. James. (2005) Subcutaneous fat in normal and diseased states. Journal of the American Academy of Dermatology 53:4, pages 671-683.
Crossref
Harini SampathJames M. Ntambi. (2005) POLYUNSATURATED FATTY ACID REGULATION OF GENES OF LIPID METABOLISM. Annual Review of Nutrition 25:1, pages 317-340.
Crossref
Sarawut Jitrapakdee, Marc Slawik, Gema Medina-Gomez, Mark Campbell, John C. Wallace, Jaswinder K. Sethi, Stephen O'Rahilly & Antonio J. Vidal-Puig. (2005) The Peroxisome Proliferator-activated Receptor-γ Regulates Murine Pyruvate Carboxylase Gene Expression in Vivo and in Vitro. Journal of Biological Chemistry 280:29, pages 27466-27476.
Crossref
Fábio T. S. Nogueira, Jiri Borecký, Aníbal E. Vercesi & Paulo Arruda. (2005) Genomic Structure and Regulation of Mitochondrial Uncoupling Protein Genes in Mammals and Plants. Bioscience Reports 25:3-4, pages 209-226.
Crossref
Jan Nedergaard, Natasa Petrovic, Eva M. Lindgren, Anders Jacobsson & Barbara Cannon. (2005) PPARγ in the control of brown adipocyte differentiation. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1740:2, pages 293-304.
Crossref
P Puigserver. (2005) Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-α. International Journal of Obesity 29:S1, pages S5-S9.
Crossref
Sandeep S. Vansal. (2004) β 3 -Adrenergic Receptor Agonists and Other Potential Anti-obesity Agents . American Journal of Pharmaceutical Education 68:3, pages 69.
Crossref
Sheila Collins, Wenhong Cao & Jacques Robidoux. (2004) Learning New Tricks from Old Dogs: β-Adrenergic Receptors Teach New Lessons on Firing Up Adipose Tissue Metabolism. Molecular Endocrinology 18:9, pages 2123-2131.
Crossref
Eva M. LINDGREN, Ronni NIELSEN, Natasa PETROVIC, Anders JACOBSSON, Susanne MANDRUP, Barbara CANNON & Jan NEDERGAARD. (2004) Noradrenaline represses PPAR (peroxisome-proliferator-activated receptor) γ2 gene expression in brown adipocytes: intracellular signalling and effects on PPARγ2 and PPARγ1 protein levels. Biochemical Journal 382:2, pages 597-606.
Crossref
Enrique Rodríguez, Joan Ribot, Ana M. Rodríguez & Andreu Palou. (2004) PPAR-γ2 Expression in Response to Cafeteria Diet: Gender- and Depot-Specific Effects. Obesity Research 12:9, pages 1455-1463.
Crossref
Sheng-Cai Lin & Peng Li. (2004) CIDE-A, a novel link between brown adipose tissue and obesity. Trends in Molecular Medicine 10:9, pages 434-439.
Crossref
Véronique Leray, Constance Gayet, Lucile Martin, Henri Dumon, Brigitte Siliart & Patrick Nguyen. (2004) Modulation of Uncoupling Protein 1 and Peroxisome Proliferator-Activated Receptor γ Expression in Adipose Tissue in Obese Insulin-Resistant Dogs. The Journal of Nutrition 134:8, pages 2154S-2157S.
Crossref
Marcus Katoh, Susanne Feldhaus, Tobias Schnitzer, Sabine Bauer & Udo Schumacher. (2004) Limited tumor growth (HT29) in vivo under RO205-2349 is due to increased apoptosis and reduced cell volume but not to decreased proliferation rate. Cancer Letters 210:1, pages 7-15.
Crossref
Jong S. Rim, Bingzhong Xue, Barbara Gawronska-Kozak & Leslie P. Kozak. (2004) Sequestration of Thermogenic Transcription Factors in the Cytoplasm during Development of Brown Adipose Tissue. Journal of Biological Chemistry 279:24, pages 25916-25926.
Crossref
Göran Leonardsson, Jenny H. Steel, Mark Christian, Victoria Pocock, Stuart Milligan, Jimmy Bell, Po-Wah So, Gema Medina-Gomez, Antonio Vidal-Puig, Roger White & Malcolm G. Parker. (2004) Nuclear receptor corepressor RIP140 regulates fat accumulation. Proceedings of the National Academy of Sciences 101:22, pages 8437-8442.
Crossref
Maki Ueta, Masanori Wakisaka, Tetsuro Ago, Takanari Kitazono, Udai Nakamura, Mototaka Yoshinari, Masanori Iwase & Mitsuo Iida. (2004) PPARγ ligands attenuate mesangial contractile dysfunction in high glucose. Kidney International 65:3, pages 961-971.
Crossref
BARBARA CANNON & JAN NEDERGAARD. (2004) Brown Adipose Tissue: Function and Physiological Significance. Physiological Reviews 84:1, pages 277-359.
Crossref
Andrea L Hevener, Weimin He, Yaacov Barak, Jamie Le, Gautam Bandyopadhyay, Peter Olson, Jason Wilkes, Ronald M Evans & Jerrold Olefsky. (2003) Muscle-specific Pparg deletion causes insulin resistance. Nature Medicine 9:12, pages 1491-1497.
Crossref
Li Yang, Dong Yan, Cong Yan & Hong Du. (2003) Peroxisome Proliferator-activated Receptor γ and Ligands Inhibit Surfactant Protein B Gene Expression in the Lung. Journal of Biological Chemistry 278:38, pages 36841-36847.
Crossref
Claire Tiraby, Geneviève Tavernier, Corinne Lefort, Dominique Larrouy, Frédéric Bouillaud, Daniel Ricquier & Dominique Langin. (2003) Acquirement of Brown Fat Cell Features by Human White Adipocytes. Journal of Biological Chemistry 278:35, pages 33370-33376.
Crossref
Michael D. Aleo, Gregg R. Lundeen, David K. Blackwell, Ward M. Smith, Gerald L. Coleman, Stanley W. Stadnicki & William M. Kluwe. (2003) Mechanism and Implications of Brown Adipose Tissue Proliferation in Rats and Monkeys Treated with the Thiazolidinedione Darglitazone, a Potent Peroxisome Proliferator-Activated Receptor-γ Agonist. Journal of Pharmacology and Experimental Therapeutics 305:3, pages 1173-1182.
Crossref
Jeffrey M Peters, Toshifumi Aoyama, Amanda M Burns & Frank J Gonzalez. (2003) Bezafibrate is a dual ligand for PPARα and PPARβ: studies using null mice. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1632:1-3, pages 80-89.
Crossref
Eiki Kanbe, Akihiro Abe, Masayuki Towatari, Tsutomu Kawabe, Hidehiko Saito & Nobuhiko Emi. (2003) DR1-like element in human topoisomerase IIα gene involved in enhancement of etoposide-induced apoptosis by PPARγ ligand. Experimental Hematology 31:4, pages 300-308.
Crossref
Philip D. G. Miles, Yaacov Barak, Ronald M. Evans & Jerrold M. Olefsky. (2003) Effect of heterozygous PPARγ deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding. American Journal of Physiology-Endocrinology and Metabolism 284:3, pages E618-E626.
Crossref
Angela M. Valverde, Mónica Arribas, Cecilia Mur, Paloma Navarro, Sebastián Pons, Anne-Marie Cassard-Doulcier, C. Ronald Kahn & Manuel Benito. (2003) Insulin-induced Up-regulated Uncoupling Protein-1 Expression Is Mediated by Insulin Receptor Substrate 1 through the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway in Fetal Brown Adipocytes. Journal of Biological Chemistry 278:12, pages 10221-10231.
Crossref
Pere Puigserver & Bruce M. Spiegelman. (2003) Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator. Endocrine Reviews 24:1, pages 78-90.
Crossref
Teresa Teruel, Rosario Hernandez, Manuel Benito & Margarita Lorenzo. (2003) Rosiglitazone and Retinoic Acid Induce Uncoupling Protein-1 (UCP-1) in a p38 Mitogen-activated Protein Kinase-dependent Manner in Fetal Primary Brown Adipocytes. Journal of Biological Chemistry 278:1, pages 263-269.
Crossref
Masaki Watanabe, Kouichi Inukai, Hideki Katagiri, Takuya Awata, Yoshitomo Oka & Shigehiro Katayama. (2003) Regulation of PPARγ transcriptional activity in 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications 300:2, pages 429-436.
Crossref
Enzo Nisoli, Laura Regianini, Luca Briscini, Alessandra Bulbarelli, Luca Busetto, Alessandra Coin, Giuliano Enzi & Michele O Carruba. (2002) Multiple symmetric lipomatosis may be the consequence of defective noradrenergic modulation of proliferation and differentiation of brown fat cells. The Journal of Pathology 198:3, pages 378-387.
Crossref
Jong S. Rim & Leslie P. Kozak. (2002) Regulatory Motifs for CREB-binding Protein and Nfe2l2 Transcription Factors in the Upstream Enhancer of the Mitochondrial Uncoupling Protein 1 Gene. Journal of Biological Chemistry 277:37, pages 34589-34600.
Crossref
Hannes Oberkofler, Harald Esterbauer, Veronika Linnemayr, A. Donny Strosberg, Franz Krempler & Wolfgang Patsch. (2002) Peroxisome Proliferator-activated Receptor (PPAR) γ Coactivator-1 Recruitment Regulates PPAR Subtype Specificity. Journal of Biological Chemistry 277:19, pages 16750-16757.
Crossref
Tatjana Albrektsen, Klaus Stensgaard Frederiksen, William E. Holmes, Esper Boel, Karen TaylorJan Fleckner. (2002) Novel Genes Regulated by the Insulin Sensitizer Rosiglitazone During Adipocyte Differentiation. Diabetes 51:4, pages 1042-1051.
Crossref
Barbara Fischer, Andreas von Knethen & Bernhard Brüne. (2002) Dualism of Oxidized Lipoproteins in Provoking and Attenuating the Oxidative Burst in Macrophages: Role of Peroxisome Proliferator-Activated Receptor-γ. The Journal of Immunology 168:6, pages 2828-2834.
Crossref
Lena Serghides, Salima Nathoo, Sharon Walmsley & Kevin C. Kain. (2002) CD36 deficiency induced by antiretroviral therapy. AIDS 16:3, pages 353-358.
Crossref
Robert Walczak & Peter Tontonoz. (2002) PPARadigms and PPARadoxes: expanding roles for PPARγ in the control of lipid metabolism. Journal of Lipid Research 43:2, pages 177-186.
Crossref
Sarah G. Harris & Richard P. Phipps. (2002) Prostaglandin D2, its metabolite 15-d-PGJ2, and peroxisome proliferator activated receptor-gamma agonists induce apoptosis in transformed, but not normal, human T lineage cells. Immunology 105:1, pages 23-34.
Crossref
V. Garcia Palacios, I. Morita & S. Murota. (2001) Expression of adipogenesis markers in a murine stromal cell line treated with 15-deoxy Δ12,14-prostaglandin J2, interleukin-11, 9-cis retinoic acid and vitamin K2. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 65:4, pages 215-221.
Crossref
Ana M. Rodríguez, Santiago Quevedo-Coli, Pilar Roca & Andreu Palou. (2001) Sex-Dependent Dietary Obesity, Induction of UCPs, and Leptin Expression in Rat Adipose Tissues. Obesity Research 9:9, pages 579-588.
Crossref
Sherin U Devaskar. (2001) Neurohumoral regulation of body weight gain. Pediatric Diabetes 2:3, pages 131-144.
Crossref
Joan Ribot, Francisco Felipe, M. Luisa Bonet & Andreu Palou. (2001) Changes of Adiposity in Response to Vitamin A Status Correlate with Changes of PPARγ2 Expression. Obesity Research 9:8, pages 500-509.
Crossref
Wenhong Cao, Alexander V. Medvedev, Kiefer W. Daniel & Sheila Collins. (2001) β-Adrenergic Activation of p38 MAP Kinase in Adipocytes. Journal of Biological Chemistry 276:29, pages 27077-27082.
Crossref
Timothy M. WillsonMillard H. LambertSteven A. Kliewer. (2001) Peroxisome Proliferator–Activated Receptor γ and Metabolic Disease. Annual Review of Biochemistry 70:1, pages 341-367.
Crossref
Javier Margareto, Javier Gómez-Ambrosi, Amelia Marti & J.Alfredo Martínez. (2001) Time-Dependent Effects of a High-Energy-Yielding Diet on the Regulation of Specific White Adipose Tissue Genes. Biochemical and Biophysical Research Communications 283:1, pages 6-11.
Crossref
Javier Margareto, Amelia Marti & J.Alfredo Martı́nez. (2001) Changes in UCP mRNA expression levels in brown adipose tissue and skeletal muscle after feeding a high-energy diet and relationships with leptin, glucose and PPARγ. The Journal of Nutritional Biochemistry 12:3, pages 130-137.
Crossref
Michael E. Spurlock, Shaoquan Q. Ji, Rebecca L. Godat, Joanne L. Kuske, Gawain M. Willis, G.Robert Frank & Steven G. Cornelius. (2001) Changes in the expression of uncoupling proteins and lipases in porcine adipose tissue and skeletal muscle during feed deprivation☆11☆ Purdue Univ. Agric. Res. Programs journal paper no. 16265. This study was presented in part at the 1999 meeting of the Midwestern Section, American Society of Animal Science, Des Moines, IA USA.. The Journal of Nutritional Biochemistry 12:2, pages 81-87.
Crossref
Bruce M. Spiegelman & Jeffrey S. Flier. (2001) Obesity and the Regulation of Energy Balance. Cell 104:4, pages 531-543.
Crossref
M. José Barberá, Agatha Schlüter, Neus Pedraza, Roser Iglesias, Francesc Villarroya & Marta Giralt. (2001) Peroxisome Proliferator-activated Receptor α Activates Transcription of the Brown Fat Uncoupling Protein-1 Gene. Journal of Biological Chemistry 276:2, pages 1486-1493.
Crossref
M. José Santi Cano, Antonio Barba Chacón & Alipio Mangas Rojas. (2001) Bases moleculares de la obesidad: regulación del apetito y control del metabolismo energético. Medicina Clínica 117:12, pages 463-476.
Crossref
Maria del Mar Gonzalez-Barroso, Claire Pecqueur, Chantal Gelly, Daniel Sanchis, Marie-Clotilde Alves-Guerra, Frederic Bouillaud, Daniel Ricquier & Anne-Marie Cassard-Doulcier. (2000) Transcriptional Activation of the Human ucp1 Gene in a Rodent Cell Line. Journal of Biological Chemistry 275:41, pages 31722-31732.
Crossref
M. Del Mar Gonzalez-Barroso, D. Ricquier & A.-M. Cassard-Doulcier. (2000) The human uncoupling protein-1 gene (UCP1): present status and perspectives in obesity research. Obesity Reviews 1:2, pages 61-72.
Crossref
Shamina M. RangwalaMitchell A. Lazar. (2000) T RANSCRIPTIONAL C ONTROL OF A DIPOGENESIS . Annual Review of Nutrition 20:1, pages 535-559.
Crossref
Leslie P. KozakMary-Ellen Harper. (2000) Mitochondrial Uncoupling Proteins in Energy Expenditure. Annual Review of Nutrition 20:1, pages 339-363.
Crossref
Alexey V. Ershov & Nicolas G. Bazan. (2000) Photoreceptor phagocytosis selectively activates PPAR? expression in retinal pigment epithelial cells. Journal of Neuroscience Research 60:3, pages 328-337.
Crossref
Bradford B. Lowell & Bruce M. Spiegelman. (2000) Towards a molecular understanding of adaptive thermogenesis. Nature 404:6778, pages 652-660.
Crossref
KARIN A. J. M. VAN DER LEE, PETER H. M. WILLEMSEN, GER J. VAN DER VUSSE & MARC VAN BILSEN. (2000) Effects of fatty acids on uncoupling protein‐2 expression in the rat heart. The FASEB Journal 14:3, pages 495-502.
Crossref
Pascal Escher & Walter Wahli. (2000) Peroxisome proliferator-activated receptors: insight into multiple cellular functions. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 448:2, pages 121-138.
Crossref
Philip D.G. Miles, Yaacov Barak, Weiman He, Ronald M. Evans & Jerrold M. Olefsky. (2000) Improved insulin-sensitivity in mice heterozygous for PPAR-γ deficiency. Journal of Clinical Investigation 105:3, pages 287-292.
Crossref
Timothy M. Willson, Peter J. Brown, Daniel D. Sternbach & Brad R. Henke. (2000) The PPARs:  From Orphan Receptors to Drug Discovery. Journal of Medicinal Chemistry 43:4, pages 527-550.
Crossref
Akiko Suzuki, Toru Yasuno, Hitoshi Kojo, Jiro Hirosumi, Seitaro Mutoh & Yoshitada Notsu. (2000) Alteration in Expression Profiles of a Series of Diabetes-Related Genes in db/db Mice Following Treatment With Thiazolidinediones. Japanese Journal of Pharmacology 84:2, pages 113-123.
Crossref
Brigitte I Frohnert & David A Bernlohr. (2000) Regulation of fatty acid transporters in mammalian cells. Progress in Lipid Research 39:1, pages 83-107.
Crossref
Gema Medina, Ciaran Sewter & Antonio J Vidal Puig. (2000) PPARγ y tiazolidinedionas, algo más que un tratamiento contra la diabetes. Medicina Clínica 115:10, pages 392-397.
Crossref
Béatrice Desvergne & Walter Wahli. (1999) Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*. Endocrine Reviews 20:5, pages 649-688.
Crossref
Yaacov Barak, Michael C Nelson, Estelita S Ong, Ying Z Jones, Pilar Ruiz-Lozano, Kenneth R Chien, Alan Koder & Ronald M Evans. (1999) PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development. Molecular Cell 4:4, pages 585-595.
Crossref
Teresa Teruel, John C. Clapham & Stephen A. Smith. (1999) PPARα Activation by Wy 14643 Induces Transactivation of the Rat UCP-1 Promoter without Increasing UCP-1 mRNA Levels and Attenuates PPARγ-Mediated Increases in UCP-1 mRNA Levels Induced by Rosiglitazone in Fetal Rat Brown Adipocytes. Biochemical and Biophysical Research Communications 264:2, pages 311-315.
Crossref
M.A. Breider, A.W. Gough, J.R. Haskins, G. Sobocinski & F.A. De La Iglesia. (2016) Troglitazone-Induced Heart and Adipose Tissue Cell Proliferation in Mice. Toxicologic Pathology 27:5, pages 545-552.
Crossref
Hebe M. Guardiola-Diaz, Stefan Rehnmark, Nobuteru Usuda, Tatjana Albrektsen, Dorothee Feltkamp, Jan-Åke Gustafsson & Stefan E.H. Alexson. (1999) Rat Peroxisome Proliferator-activated Receptors and Brown Adipose Tissue Function during Cold Acclimatization. Journal of Biological Chemistry 274:33, pages 23368-23377.
Crossref
Angel Valmaseda, M.Carmen Carmona, M.José Barberá, Octavi Viñas, Teresa Mampel, Roser Iglesias, Francesc Villarroya & Marta Giralt. (1999) Opposite regulation of PPAR-α and -γ gene expression by both their ligands and retinoic acid in brown adipocytes. Molecular and Cellular Endocrinology 154:1-2, pages 101-109.
Crossref
Maria Febbraio, Nada A. Abumrad, David P. Hajjar, Kavita Sharma, Wanli Cheng, S. Frieda A. Pearce & Roy L. Silverstein. (1999) A Null Mutation in Murine CD36 Reveals an Important Role in Fatty Acid and Lipoprotein Metabolism. Journal of Biological Chemistry 274:27, pages 19055-19062.
Crossref
Zhidan Wu, Pere Puigserver, Ulf Andersson, Chenyu Zhang, Guillaume Adelmant, Vamsi Mootha, Amy Troy, Saverio Cinti, Bradford Lowell, Richard C. Scarpulla & Bruce M. Spiegelman. (1999) Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1. Cell 98:1, pages 115-124.
Crossref
Cheng-Shine Hwang & M.Daniel Lane. (1999) Up-Regulation of Uncoupling Protein-3 by Fatty Acid in C2C12 Myotubes. Biochemical and Biophysical Research Communications 258:2, pages 464-469.
Crossref
George D. Demetri, Christopher D. M. Fletcher, Elisabetta Mueller, Pasha Sarraf, Ryan Naujoks, Natalee Campbell, Bruce M. Spiegelman & Samuel Singer. (1999) Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-γ ligand troglitazone in patients with liposarcoma. Proceedings of the National Academy of Sciences 96:7, pages 3951-3956.
Crossref
Brigitte I. Frohnert, To Y. Hui & David A. Bernlohr. (1999) Identification of a Functional Peroxisome Proliferator-responsive Element in the Murine Fatty Acid Transport Protein Gene. Journal of Biological Chemistry 274:7, pages 3970-3977.
Crossref
Yasushi Teshima, Tetsunori Saikawa, Hidetoshi Yonemochi, Shuji Hidaka, Hironobu Yoshimatsu & Toshiie Sakata. (1999) Alteration of heart uncoupling protein-2 mRNA regulated by sympathetic nerve and triiodothyronine during postnatal period in rats. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1448:3, pages 409-415.
Crossref
Vered Ribon, John H. Johnson, Heidi S. Camp & Alan R. Saltiel. (1998) Thiazolidinediones and insulin resistance: Peroxisome proliferatoractivated receptor γ activation stimulates expression of the CAP gene . Proceedings of the National Academy of Sciences 95:25, pages 14751-14756.
Crossref
Linda J. KellyPasquale P. VicarioG. Marie ThompsonMari R. CandeloreThomas W. DoebberJohn VentreMargaret S. WuRoger MeurerMichael J. ForrestMichael W. Conner, Margaret A. CascieriDavid E. Moller. (1998) Peroxisome Proliferator-Activated Receptors γ and α Mediate in Vivo Regulation of Uncoupling Protein (UCP-1, UCP-2, UCP-3) Gene Expression. Endocrinology 139:12, pages 4920-4927.
Crossref
B. Cambon, Y. Reyne & J. Nouguès. (1998) In vitro induction of UCP1 mRNA in preadipocytes from rabbit considered as a model of large mammals brown adipose tissue development: importance of PPARγ agonists for cells isolated in the postnatal period. Molecular and Cellular Endocrinology 146:1-2, pages 49-58.
Crossref
Enzo Nisoli, Emilio Clementi, Cristina Tonello, Clara Sciorati, Luca Briscini & Michele O Carruba. (1998) Effects of nitric oxide on proliferation and differentiation of rat brown adipocytes in primary cultures. British Journal of Pharmacology 125:4, pages 888-894.
Crossref
Steven A Kliewer & Timothy M Willson. (1998) The nuclear receptor PPARγ-bigger than fat. Current Opinion in Genetics & Development 8:5, pages 576-581.
Crossref
Teruhiko Shimokawa, Miyuki Kato, Yuka Watanabe, Reiko Hirayama, Eiji Kurosaki, Hisataka Shikama & Seiichi Hashimoto. (1998) In VivoEffects of Pioglitazone on Uncoupling Protein-2 and -3 mRNA Levels in Skeletal Muscle of Hyperglycemic KK Mice. Biochemical and Biophysical Research Communications 251:1, pages 374-378.
Crossref
A. Schäffler, T. Langmann, K.-D. Palitzsch, J. Schölmerich & G. Schmitz. (1998) Identification and characterization of the human adipocyte apM-1 promoter. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1399:2-3, pages 187-197.
Crossref
Pilar Yubero, MaJosé Barberá, Rosa Alvarez, Octavi Viñas, Teresa Mampel, Roser Iglesias, Francesc Villarroya & Marta Giralt. (1998) Dominant Negative Regulation by c-Jun of Transcription of the Uncoupling Protein-1 Gene through a Proximal cAMP-Regulatory Element: A Mechanism for Repressing Basal and Norepinephrine-Induced Expression of the Gene before Brown Adipocyte Differentiation. Molecular Endocrinology 12:7, pages 1023-1037.
Crossref
Bradford B. Lowell. (1998) Adaptive thermogenesis: Turning on the heat. Current Biology 8:15, pages R517-R520.
Crossref
Olivier Braissant & Walter Wahli. (1998) Differential Expression of Peroxisome Proliferator-Activated Receptor-α, -β, and -γ during Rat Embryonic Development*. Endocrinology 139:6, pages 2748-2754.
Crossref
Peter Tontonoz, Laszlo Nagy, Jacqueline G.A Alvarez, Vilmos A Thomazy & Ronald M Evans. (1998) PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL. Cell 93:2, pages 241-252.
Crossref
Pere Puigserver, Zhidan Wu, Cheol Won Park, Reed Graves, Margaret Wright & Bruce M Spiegelman. (1998) A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis. Cell 92:6, pages 829-839.
Crossref
Rogério Rabelo, Anne Camirand & J. Enrique Silva. (1997) 3′,5′-Cyclic Adenosine Monophosphate-Response Sequences of the Uncoupling Protein Gene Are Sequentially Recruited During Darglitazone-Induced Brown Adipocyte Differentiation*. Endocrinology 138:12, pages 5325-5332.
Crossref
Rick B. Vega & Daniel P. Kelly. (1997) A Role for Estrogen-related Receptor α in the Control of Mitochondrial Fatty Acid β-Oxidation during Brown Adipocyte Differentiation. Journal of Biological Chemistry 272:50, pages 31693-31699.
Crossref

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