Advanced search
Publication Cover
Molecular and Cellular Biology Volume 16, 1996 - Issue 7
Submit an article Journal homepage
5
Views
107
CrossRef citations to date
0
Altmetric
Research Article

A Dominant Inhibitory Mutant of the Type II Transforming Growth Factor β Receptor in the Malignant Progression of a Cutaneous T-Cell Lymphoma

Petra I. Knaus1 Whitehead Institute for Biomedical Research, Cambridge, Massachusetts02142
,
Dirk Lindemann1 Whitehead Institute for Biomedical Research, Cambridge, Massachusetts02142
,
John F. DeCoteau2 Department of Pathology, Beth Israel Hospital and Harvard Medical School, Boston, Massachusetts02215
,
Riki Perlman1 Whitehead Institute for Biomedical Research, Cambridge, Massachusetts02142
,
Haya Yankelev1 Whitehead Institute for Biomedical Research, Cambridge, Massachusetts02142
,
Merrill Hille1 Whitehead Institute for Biomedical Research, Cambridge, Massachusetts02142
,
Marshall E. Kadin2 Department of Pathology, Beth Israel Hospital and Harvard Medical School, Boston, Massachusetts02215
&
Harvey F. Lodish1 Whitehead Institute for Biomedical Research, Cambridge, Massachusetts02142;3 Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts02139Correspondence[email protected]
 show all
Pages 3480-3489 | Received 13 Mar 1996, Accepted 11 Apr 1996, Published online: 29 Mar 2023

Citations (107)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Shiri Kfir, Marcelo Ehrlich, Ayelet Goldshmid, Xuedong Liu, Yoel Kloog & Yoav I. Henis. (2005) Pathway- and Expression Level-Dependent Effects of Oncogenic N-Ras: p27Kip1 Mislocalization by the Ral-GEF Pathway and Erk-Mediated Interference with Smad Signaling. Molecular and Cellular Biology 25:18, pages 8239-8250.
Read now
Virginia G Kaklamani & Boris Pasche. (2004) Role of TGF-β in cancer and the potential for therapy and prevention. Expert Review of Anticancer Therapy 4:4, pages 649-661.
Read now
Heather M. Rooke, Kathryn E. Crosier. (2001) THE SMAD PROTEINS AND TGFβ SIGNALLING: UNCOVERING A PATHWAY CRITICAL IN CANCER. Pathology 33:1, pages 73-84.
Read now

Articles from other publishers (104)

Joseph H. ChoeJasper Z. WilliamsWendell A. Lim. (2020) Engineering T Cells to Treat Cancer: The Convergence of Immuno-Oncology and Synthetic Biology. Annual Review of Cancer Biology 4:1, pages 121-139.
Crossref
Anna Stelling, Hind Hashwah, Katrin Bertram, Markus G. Manz, Alexandar Tzankov & Anne Müller. (2018) The tumor suppressive TGF-β/SMAD1/S1PR2 signaling axis is recurrently inactivated in diffuse large B-cell lymphoma. Blood 131:20, pages 2235-2246.
Crossref
Ryanne A. Brown, Sebastian Fernandez-Pol & Jinah Kim. (2017) Primary cutaneous anaplastic large cell lymphoma. Journal of Cutaneous Pathology 44:6, pages 570-577.
Crossref
. 2016. The Cutaneous Lymphoid Proliferations. The Cutaneous Lymphoid Proliferations 274 311 .
Cedric Carl, Anne Flindt, Julian Hartmann, Markus Dahlke, Dirk Rades, Jürgen Dunst, Hendrik Lehnert, Frank Gieseler & Hendrik Ungefroren. (2015) Ionizing radiation induces a motile phenotype in human carcinoma cells in vitro through hyperactivation of the TGF-beta signaling pathway. Cellular and Molecular Life Sciences 73:2, pages 427-443.
Crossref
Justin L. Chen, Timothy D. Colgan, Kelly L. Walton, Paul Gregorevic & Craig A. Harrison. 2016. Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease. Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease 97 131 .
Freda Laulicht, Jason Brocato, Laura Cartularo, Joshua Vaughan, Feng Wu, Thomas Kluz, Hong Sun, Betul Akgol Oksuz, Steven Shen, Massimiliano Peana, Serenella Medici, Maria Antonietta Zoroddu & Max Costa. (2015) Tungsten-induced carcinogenesis in human bronchial epithelial cells. Toxicology and Applied Pharmacology 288:1, pages 33-39.
Crossref
Ulrika Blank & Stefan Karlsson. (2015) TGF-β signaling in the control of hematopoietic stem cells. Blood 125:23, pages 3542-3550.
Crossref
Tzu-Pei Chang, Vladimir Poltoratsky & Ivana Vancurova. (2015) Bortezomib Inhibits Expression of TGF-β1, IL-10, and CXCR4, Resulting in Decreased Survival and Migration of Cutaneous T Cell Lymphoma Cells. The Journal of Immunology 194:6, pages 2942-2953.
Crossref
HONG CHEN, JING-WEI WANG, LI-XIN LIU, JI-DONG YAN, SHU-HUA REN, YAN LI & ZHENG LU. (2015) Expression and significance of transforming growth factor-β receptor type II and DPC4/Smad4 in non-small cell lung cancer. Experimental and Therapeutic Medicine 9:1, pages 227-231.
Crossref
Katrina Shamalov, Yair Tal, Chen Ankri & Cyrille J. Cohen. 2014. Interaction of Immune and Cancer Cells. Interaction of Immune and Cancer Cells 207 232 .
B.O. Dulmage & L.J. Geskin. (2013) Lessons learned from gene expression profiling of cutaneous T-cell lymphoma. British Journal of Dermatology 169:6, pages 1188-1197.
Crossref
L Zhang, Z Yu, P Muranski, D C Palmer, N P Restifo, S A Rosenberg & R A Morgan. (2012) Inhibition of TGF-β signaling in genetically engineered tumor antigen-reactive T cells significantly enhances tumor treatment efficacy. Gene Therapy 20:5, pages 575-580.
Crossref
William M. Grady. 2013. Molecular Pathogenesis of Colorectal Cancer. Molecular Pathogenesis of Colorectal Cancer 201 230 .
Lenka Kubiczkova, Lenka Sedlarikova, Roman Hajek & Sabina Sevcikova. (2012) TGF-β – an excellent servant but a bad master. Journal of Translational Medicine 10:1.
Crossref
Weici Zhang, Masanobu Tsuda, Guo-Xiang Yang, Koichi Tsuneyama, Xiao-Song He, Aftab A. Ansari, William M. Ridgway, Ross L. Coppel, Zhe-Xiong Lian, Patrick S.C. Leung & M. Eric Gershwin. (2012) Lymphoma-Like T Cell Infiltration in Liver Is Associated with Increased Copy Number of Dominant Negative Form of TGFβ Receptor II. PLoS ONE 7:11, pages e49413.
Crossref
U Blank & S Karlsson. (2011) The role of Smad signaling in hematopoiesis and translational hematology. Leukemia 25:9, pages 1379-1388.
Crossref
Marsha C. Kinney, Russell A. Higgins & Edward A. Medina. (2011) Anaplastic Large Cell Lymphoma: Twenty-Five Years of Discovery. Archives of Pathology & Laboratory Medicine 135:1, pages 19-43.
Crossref
Marshall E. Kadin. 2011. Hematopathology. Hematopathology 604 616 .
Zhe Lei, Reng-Yun Liu, Jun Zhao, Zeyi Liu, Xiefang Jiang, Weiming You, Xiao-Feng Chen, Xia Liu, Kui Zhang, Boris Pasche & Hong-Tao Zhang. (2009) TGFBR1 Haplotypes and Risk of Non–Small-Cell Lung Cancer . Cancer Research 69:17, pages 7046-7052.
Crossref
Leslie E. Huye & Cliona M. Rooney. 2009. DNA Tumor Viruses. DNA Tumor Viruses 379 401 .
Lise Mette Gjerdrum, Anders Woetmann, Niels Odum, Christoffer Hother, Regitze Henrik-Nielsen, Robert Gniadecki & Elisabeth Ralfkiaer. (2008) FOXP3 positive regulatory T-cells in cutaneous and systemic CD30 positive T-cell lymphoproliferations. European Journal of Haematology 80:6, pages 483-489.
Crossref
Jai Hyang Go. (2008) Altered Expression of Smad Proteins in T or NK-cell Lymphomas. Cancer Research and Treatment 40:4, pages 197.
Crossref
Guiying Y. Wang, Xiaochua H. Hu, Rongmei M. Zhang, Lindsey J. Leach & Zewei W. Luo. 2008. Transforming Growth Factor-β in Cancer Therapy, Volume II. Transforming Growth Factor-β in Cancer Therapy, Volume II 79 93 .
Hendrik Ungefroren. 2008. Transforming Growth Factor-β in Cancer Therapy, Volume II. Transforming Growth Factor-β in Cancer Therapy, Volume II 51 62 .
Nancy L. McCartney-Francis & Sharon M. Wahl. 2008. Transforming Growth Factor-β in Cancer Therapy, Volume II. Transforming Growth Factor-β in Cancer Therapy, Volume II 553 570 .
Catherine M. Bollard & Cliona M. Rooney. 2008. Transforming Growth Factor-β in Cancer Therapy, Volume II. Transforming Growth Factor-β in Cancer Therapy, Volume II 383 400 .
Sonia B. JakowlewNanjoo Suh. 2008. Transforming Growth Factor-β in Cancer Therapy, Volume I. Transforming Growth Factor-β in Cancer Therapy, Volume I 525 547 .
Melissa Yana Frederic, Dalil Hamroun, Laurence Faivre, Catherine Boileau, Guillaume Jondeau, Mireille Claustres, Christophe Béroud & Gwenaëlle Collod-Béroud. (2008) A new locus-specific database (LSDB) for mutations in the TGFBR2 gene: UMD- TGFBR2 . Human Mutation 29:1, pages 33-38.
Crossref
Heike Peterziel, Tina Paech, Jens Strelau, Klaus Unsicker & Kerstin Krieglstein. (2007) Specificity in the crosstalk of TGFβ/GDNF family members is determined by distinct GFR alpha receptors. Journal of Neurochemistry 103:6, pages 2491-2504.
Crossref
Sushanta Banerjee, Gibanananda Ray, Peter Van Veldhuizen & Snigdha Banerjee. 2007. Anti-Angiogenic Functional and Medicinal Foods. Anti-Angiogenic Functional and Medicinal Foods 365 388 .
Claudia Droc, Hernani D. Cualing & Marshall E. Kadin. (2017) Need for an Improved Molecular/Genetic Classification for CD30+ Lymphomas Involving the Skin. Cancer Control 14:2, pages 124-132.
Crossref
Katerina Pardali & Aristidis Moustakas. (2007) Actions of TGF-β as tumor suppressor and pro-metastatic factor in human cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1775:1, pages 21-62.
Crossref
Klaus Podar, Noopur Raje & Kenneth C. Anderson. 2007. Targeted Interference with Signal Transduction Events. Targeted Interference with Signal Transduction Events 77 97 .
Alyssa R. Bonine-Summers, Brian K. Law & Harold L. Moses. 2007. Cytokines in the Genesis and Treatment of Cancer. Cytokines in the Genesis and Treatment of Cancer 91 111 .
Anita Buck & Volker Ellenrieder. (2006) Recent advances in TGFβ-regulated transcription during carcinogenesis. Signal Transduction 6:5, pages 345-354.
Crossref
Gábor Mátyás, Eliane Arnold, Thierry Carrel, Daniela Baumgartner, Catherine Boileau, Wolfgang Berger & Beat Steinmann. (2006) Identification and in silico analyses of novelTGFBR1 andTGFBR2 mutations in Marfan syndrome-related disorders. Human Mutation 27:8, pages 760-769.
Crossref
Eric C. Vonderheid & Marshall E. Kadin. (2006) Papular mycosis fungoides: A variant of mycosis fungoides or lymphomatoid papulosis?. Journal of the American Academy of Dermatology 55:1, pages 177-180.
Crossref
Mei DongGerard C. Blobe. (2006) Role of transforming growth factor-β in hematologic malignancies. Blood 107:12, pages 4589-4596.
Crossref
Patrick T. Walsh, Bernice M. Benoit, Maria Wysocka, Nicole M. Dalton, Laurence A. Turka & Alain H. Rook. (2006) A Role for Regulatory T Cells in Cutaneous T-Cell Lymphoma; Induction of a CD4+CD25+Foxp3+ T-Cell Phenotype Associated with HTLV-1 Infection. Journal of Investigative Dermatology 126:3, pages 690-692.
Crossref
Marshall E. Kadin. (2006) Pathobiology of CD30+ cutaneous T-cell lymphomas. Journal of Cutaneous Pathology 33:S1, pages 10-17.
Crossref
Jonas Larsson & Stefan Karlsson. (2005) The role of Smad signaling in hematopoiesis. Oncogene 24:37, pages 5676-5692.
Crossref
Rebecca L. Elliott & Gerard C. Blobe. (2005) Role of Transforming Growth Factor Beta in Human Cancer. Journal of Clinical Oncology 23:9, pages 2078-2093.
Crossref
Hendrik Ungefroren, Stephanie Groth, Maren Ruhnke, Holger Kalthoff & Fred Fändrich. (2005) Transforming Growth Factor-β (TGF-β) Type I Receptor/ALK5-dependent Activation of the GADD45β Gene Mediates the Induction of Biglycan Expression by TGF-β. Journal of Biological Chemistry 280:4, pages 2644-2652.
Crossref
Virginia Kaklamani & Boris Pasche. 2005. Cytokines and Cancer. Cytokines and Cancer 129 156 .
Rein Willemze. 2004. Skin Immune System. Skin Immune System 691 704 .
Philip J. Lucas, Nicole McNeil, Eva Hilgenfeld, Baishakhi Choudhury, Seong-Jin Kim, Michael A. Eckhaus, Thomas Ried & Ronald E. Gress. (2004) Transforming Growth Factor-β Pathway Serves as a Primary Tumor Suppressor in CD8+ T Cell Tumorigenesis. Cancer Research 64:18, pages 6524-6529.
Crossref
Suzanne Granados & Sam T. Hwang. (2004) Roles for CD30 in the Biology and Treatment of CD30+ Lymphoproliferative Diseases. Journal of Investigative Dermatology 122:6, pages 1345-1347.
Crossref
David K Crockett, Zhaosheng Lin, Kojo SJ Elenitoba-Johnson & Megan S Lim. (2004) Identification of NPM-ALK interacting proteins by tandem mass spectrometry. Oncogene 23:15, pages 2617-2629.
Crossref
Antonella Colasante, Francesca B Aiello, Mauro Brunetti & Francesco S di Giovine. (2003) Gene expression of transforming growth factor β receptors I and II in non-small-cell lung tumors. Cytokine 24:5, pages 182-189.
Crossref
Rein Willemze & Chris J.L.M Meijer. (2003) Primary cutaneous CD30-positive lymphoproliferative disorders. Hematology/Oncology Clinics of North America 17:6, pages 1319-1332.
Crossref
S-J Kim & J Letterio. (2003) Transforming growth factor-β signaling in normal and malignant hematopoiesis. Leukemia 17:9, pages 1731-1737.
Crossref
John Barlow, David Yandell, Donald Weaver, Theresa Casey & Karen Plaut. (2003) Higher Stromal Expression of Transforming Growth Factor-beta Type II Receptors is Associated with Poorer Prognosis Breast Tumors. Breast Cancer Research and Treatment 79:2, pages 149-159.
Crossref
Sylke Gellrich, Anke Wilks, Ansgar Lukowsky, Martin Wernicke, Astrid Müller, J. Marcus Muche, Tanja Fischer, Kim Christian Jasch, Heike Audring & Wolfram Sterry. (2003) T Cell Receptor-γ Gene Analysis of CD30+ Large Atypical Individual Cells in CD30+ Large Primary Cutaneous T Cell Lymphomas. Journal of Investigative Dermatology 120:4, pages 670-675.
Crossref
M. Michael Cohen. (2003) TGF?/Smad signaling system and its pathologic correlates. American Journal of Medical Genetics 116A:1, pages 1-10.
Crossref
Hua Chang, Chester W. Brown & Martin M. Matzuk. (2002) Genetic Analysis of the Mammalian Transforming Growth Factor-β Superfamily. Endocrine Reviews 23:6, pages 787-823.
Crossref
Bertrand ArnulfAude VillemainChristophe NicotElodie MordeletPierre CharneauJoëlle KersualYaël ZermatiAlain MauvielAli BazarbachiOlivier Hermine. (2002) Human T-cell lymphotropic virus oncoprotein Tax represses TGF-β1 signaling in human T cells via c-Jun activation: a potential mechanism of HTLV-I leukemogenesis. Blood 100:12, pages 4129-4138.
Crossref
G.Chris Fillmore, Zhaosheng Lin, Sandra D Bohling, Ryan S Robetorye, Chan-Hwan Kim, Stephen D Jenson, Kojo S.J Elenitoba-Johnson & Megan S Lim. (2002) Gene expression profiling of cell lines derived from T-cell malignancies. FEBS Letters 522:1-3, pages 183-188.
Crossref
Catherine M. BollardClaudia RössigM. Julia CalongeM. Helen HulsHans-Joachim WagnerJoan MassagueMalcolm K. BrennerHelen E. HeslopCliona M. Rooney. (2002) Adapting a transforming growth factor β–related tumor protection strategy to enhance antitumor immunity. Blood 99:9, pages 3179-3187.
Crossref
Xiaolong Fan, Gudrun Valdimarsdottir, Jonas Larsson, Ann Brun, Mattias Magnusson, Sten Eirik Jacobsen, Peter ten Dijke & Stefan Karlsson. (2002) Transient Disruption of Autocrine TGF-β Signaling Leads to Enhanced Survival and Proliferation Potential in Single Primitive Human Hemopoietic Progenitor Cells. The Journal of Immunology 168:2, pages 755-762.
Crossref
Jai Hyang Go. (2002) Decreased Expression of TGF-β Type 2 Receptor in Primary B-cell Lymphomas of the Stomach. Pathology - Research and Practice 198:5, pages 333-337.
Crossref
Jin-Young Baek, Ayalew Tefferi, Animesh Pardanani & Chin-Yang Li. (2002) Immunohistochemical studies of c-kit, transforming growth factor-β, and basic fibroblast growth factor in mast cell disease. Leukemia Research 26:1, pages 83-90.
Crossref
Kara N. Smolinski & Stephen J. Meltzer. 2002. The Molecular Basis of Human Cancer. The Molecular Basis of Human Cancer 81 111 .
Rik Derynck, Rosemary J. Akhurst & Allan Balmain. (2001) TGF-β signaling in tumor suppression and cancer progression. Nature Genetics 29:2, pages 117-129.
Crossref
MARSHALL E. KADIN, EDI LEVI & WERNER KEMPF. (2006) Progression of Lymphomatoid Papulosis to Systemic Lymphoma Is Associated with Escape from Growth Inhibition by Transforming Growth Factor-β and CD30 Ligand. Annals of the New York Academy of Sciences 941:1, pages 59-68.
Crossref
Stephan Kanzler, Erik Meyer, Ansgar Wilhelm Lohse, Peter Schirmacher, Jürgen Henninger, Peter Robert Galle & Manfred Blessing. (2001) Hepatocellular expression of a dominant-negative mutant TGF-β type II receptor accelerates chemically induced hepatocarcinogenesis. Oncogene 20:36, pages 5015-5024.
Crossref
Carlos Rodriguez, Lily Jun-Shen Huang, Jennifer K. Son, Adrienne McKee, Zhan Xiao & Harvey F. Lodish. (2001) Functional Cloning of the Proto-oncogene Brain Factor-1 (BF-1) As a Smad-binding Antagonist of Transforming Growth Factor-β Signaling. Journal of Biological Chemistry 276:32, pages 30224-30230.
Crossref
Jianbo Yue & Kathleen M. Mulder. (2001) Transforming growth factor-β signal transduction in epithelial cells. Pharmacology & Therapeutics 91:1, pages 1-34.
Crossref
Koji Fujimoto, Hongmiao Sheng, Jinyi Shao & R.Daniel Beauchamp. (2001) Transforming Growth Factor-β1 Promotes Invasiveness after Cellular Transformation with Activated Ras in Intestinal Epithelial Cells. Experimental Cell Research 266:2, pages 239-249.
Crossref
Kohei Miyazono, Kiyoshi Kusanagi & Hirofumi Inoue. (2001) Divergence and convergence of TGF-?/BMP signaling. Journal of Cellular Physiology 187:3, pages 265-276.
Crossref
N Pimpinelli. (2001) Primary cutaneous CD30+ T-cell lymphomas: hypothesis for a highly distinctive clinicobiological behaviour. Journal of the European Academy of Dermatology and Venereology 15:2, pages 108-109.
Crossref
Ester Piek & Anita B. Roberts. 2001. 1 54 .
Edi Levi, Zhenxi Wang, Tina Petrogiannis-Haliotis, Walther M. Pfeifer, Werner Kempf, Reed Drews & Marshall E. Kadin. (2000) Distinct Effects of CD30 and Fas Signaling in Cutaneous Anaplastic Lymphomas: A Possible Mechanism for Disease Progression. Journal of Investigative Dermatology 115:6, pages 1034-1040.
Crossref
Nicolas O. FortunelAntoinette HatzfeldJacques A. Hatzfeld. (2000) Transforming growth factor-β: pleiotropic role in the regulation of hematopoiesis. Blood 96:6, pages 2022-2036.
Crossref
Nicolas O. FortunelAntoinette HatzfeldJacques A. Hatzfeld. (2000) Transforming growth factor-β: pleiotropic role in the regulation of hematopoiesis. Blood 96:6, pages 2022-2036.
Crossref
Gerard C. Blobe, William P. Schiemann & Harvey F. Lodish. (2000) Role of Transforming Growth Factor β in Human Disease. New England Journal of Medicine 342:18, pages 1350-1358.
Crossref
S.-J. Kim, Y.-H. Im, S.D. Markowitz & Y.-J. Bang. (2000) Molecular mechanisms of inactivation of TGF-β receptors during carcinogenesis. Cytokine & Growth Factor Reviews 11:1-2, pages 159-168.
Crossref
Nicolas Fortunel, Jacques Hatzfeld, Sergueï Kisselev, Marie‐Noëlle Monier, Karin Ducos, Angelo Cardoso, Pascal Batard & Antoinette Hatzfeld. (2009) Release from Quiescence of Primitive Human Hematopoietic Stem/Progenitor Cells by Blocking Their Cell‐Surface TGF‐β Type II Receptor in a Short‐Term In Vitro Assay. STEM CELLS 18:2, pages 102-111.
Crossref
Robert LowskyAnthony MaglioccoRyo IchinohasamaArmin ReitmairStuart ScottMichele HenryMarshall E. KadinJohn F. DeCoteau. (2000) MSH2-deficient murine lymphomas harbor insertion/deletion mutations in the transforming growth factor beta receptor type 2 gene and display low not high frequency microsatellite instability. Blood 95:5, pages 1767-1772.
Crossref
Michael Reiss. (1999) TGF-β and cancer. Microbes and Infection 1:15, pages 1327-1347.
Crossref
Christine Le Roy, Karine Maisnier-Patin, Patrick Leduque, J Yuan Li, José M Saez & Dominique Langlois. (1999) Overexpression of a dominant-negative type II TGFβ receptor tagged with green fluorescent protein inhibits the effects of TGFβ on cell growth and gene expression of mouse adrenal tumor cell line Y-1 and enhances cell tumorigenicity. Molecular and Cellular Endocrinology 158:1-2, pages 87-98.
Crossref
Kristina Detmer, Timothy A Steele, Mark A Shoop & Hassan Dannawi. (1999) Lineage-Restricted Expression of Bone Morphogenetic Protein Genes in Human Hematopoietic Cell Lines. Blood Cells, Molecules, and Diseases 25:6, pages 310-323.
Crossref
M. MoriC. ManuelliN. PimpinelliC. MaviliaE. MaggiM. SantucciB. BianchiP. CappugiB. GiannottiM.E. Kadin. (1999) CD30-CD30 Ligand Interaction in Primary Cutaneous CD30+T-Cell Lymphomas: A Clue to the Pathophysiology of Clinical Regression. Blood 94:9, pages 3077-3083.
Crossref
M. MoriC. ManuelliN. PimpinelliC. MaviliaE. MaggiM. SantucciB. BianchiP. CappugiB. GiannottiM.E. Kadin. (1999) CD30-CD30 Ligand Interaction in Primary Cutaneous CD30+T-Cell Lymphomas: A Clue to the Pathophysiology of Clinical Regression. Blood 94:9, pages 3077-3083.
Crossref
Christian Buske, Horst Hannig, Eva-Maria Schneider, Sabine Blaschke, Gerhard Hunsmann, Walter Bodemer & Wolfgang Hiddemann. (1999) Transforming Growth Factor beta Is a Growth-Inhibitory Cytokine of B Cell Lymphoma in SIV-Infected Macaques. AIDS Research and Human Retroviruses 15:16, pages 1477-1485.
Crossref
William P. SchiemannWalther M. PfeiferEdi LeviMarshall E. KadinHarvey F. Lodish. (1999) A Deletion in the Gene for Transforming Growth Factor β Type I Receptor Abolishes Growth Regulation by Transforming Growth Factor β in a Cutaneous T-Cell Lymphoma. Blood 94:8, pages 2854-2861.
Crossref
Shi-Long Lu, Masahiro Kawabata, Takeshi Imamura, Kohei Miyazono & Yasuhito Yuasa. (1999) Two Divergent Signaling Pathways for TGF-β Separated by a Mutation of Its Type II Receptor Gene. Biochemical and Biophysical Research Communications 259:2, pages 385-390.
Crossref
Hyman Engelberg. (1999) Actions of heparin that may affect the malignant process. Cancer 85:2, pages 257-272.
Crossref
Katri M. Koli & Carlos L. Arteaga. 1999. Breast Cancer. Breast Cancer 95 119 .
Kazuto Fukuda, Sumio Kawata, Shinji Tamura, Yukihiko Matsuda, Yoshiaki Inui, Takumi Igura, Satoshi Inoue, Takahiko Kudara & Yuji Matsuzawa. (1998) Altered regulation of Src tyrosine kinase by transforming growth factor ?1 in a human hepatoma cell line. Hepatology 28:3, pages 796-804.
Crossref
J. Massagué. (1998) TGF-β SIGNAL TRANSDUCTION. Annual Review of Biochemistry 67:1, pages 753-791.
Crossref
Rally Eskinazi, Anne Resibois, Michal Svoboda, Marie-Odile Peny, Michael Adler, Patrick Robberecht & Jean-Luc van Laethem. (1998) Expression of transforming growth factor β receptors in normal human colon and sporadic adenocarcinomas. Gastroenterology 114:6, pages 1211-1220.
Crossref
Kuniko Horie, Hidetoshi Yamashita, Akira Mogi, Seiichi Takenoshita & Kohei Miyazono. (1998) Lack of transforming growth factor-β type II receptor expression in human retinoblastoma cells. Journal of Cellular Physiology 175:3, pages 305-313.
Crossref
Hideo Orimo, Miyoko Ikejima, Eiitsu Nakajima, Mitsuru Emi & Takashi Shimada. (1998) A novel missense mutation and frameshift mutations in the type II receptor of transforming growth factor-β gene in sporadic colon cancer with microsatellite instability. Mutation Research/Mutation Research Genomics 382:3-4, pages 115-120.
Crossref
Stephanie R. Amoroso, Naihui Huang, Anita B. Roberts, Michael Potter & John J. Letterio. (1998) Consistent loss of functional transforming growth factor β receptor expression in murine plasmacytomas. Proceedings of the National Academy of Sciences 95:1, pages 189-194.
Crossref
Jussi Taipale, Juha Saharinen & Jorma Keski-Oja. 1998. 87 134 .
Rik Derynck & Xin-Hua Feng. (1997) TGF-β receptor signaling. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1333:2, pages F105-F150.
Crossref
John J. Letterio & Anita B. Roberts. (1997) TGF-β: A Critical Modulator of Immune Cell Function. Clinical Immunology and Immunopathology 84:3, pages 244-250.
Crossref
John F. DeCoteau, Petra I. Knaus, Haya Yankelev, Marciano D. Reis, Robert Lowsky, Harvey F. Lodish & Marshall E. Kadin. (1997) Loss of functional cell surface transforming growth factor β (TGF-β) type 1 receptor correlates with insensitivity to TGF-β in chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences 94:11, pages 5877-5881.
Crossref
Erwin P. Böttinger, John J. Letterio & Anita B. Roberts. (1997) Biology of TGF-β in knockout and transgenic mouse models. Kidney International 51:5, pages 1355-1360.
Crossref
Joan Massaous & Akiko Hata. (1997) TGF-β signalling through the Smad pathway. Trends in Cell Biology 7:5, pages 187-192.
Crossref
Robin Hesketh. 1997. The Oncogene & Tumour Suppressor Gene Factsbook. The Oncogene & Tumour Suppressor Gene Factsbook 476 485 .
Kohei Miyazono, Peter Ten Dijke, Serhiy Souchelnytskyi, Atsuhito Nakao, Takeshi Imamura, Jun-Ichi Hanai, Masahiro Kawabata & Carl-Henrik Heldin. 1997. Inhibin, Activin and Follistatin. Inhibin, Activin and Follistatin 277 284 .
Liliana Attisano & Jeffrey L. Wrana. (1996) Signal transduction by members of the transforming growth factor-β superfamily. Cytokine & Growth Factor Reviews 7:4, pages 327-339.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.