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Molecular and Cellular Biology Volume 16, 1996 - Issue 9
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Research Article

Single-Stranded-DNA Binding Alters Human Replication Protein A Structure and Facilitates Interaction with DNA-Dependent Protein Kinase

Leonard J. Blackwell1 Department of Biochemistry and Kaplan Comprehensive Cancer Center, New York University Medical Center, New York, New York10016
,
James A. Borowiec1 Department of Biochemistry and Kaplan Comprehensive Cancer Center, New York University Medical Center, New York, New York10016Correspondenceborowj01 @mcrcr.med.nyu.edu [email protected]
&
Iris A. Mastrangelo2 Biology Department, Brookhaven National Laboratory, Upton, New York11973Correspondenceborowj01 @mcrcr.med.nyu.edu [email protected]
Pages 4798-4807 | Received 15 Apr 1996, Accepted 12 Jun 1996, Published online: 29 Mar 2023

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Yang Liu, Sivaraja Vaithiyalingam, Qiong Shi, Walter J. Chazin & Sandra S. Zinkel. (2011) BID Binds to Replication Protein A and Stimulates ATR Function following Replicative Stress. Molecular and Cellular Biology 31:21, pages 4298-4309.
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Derek J. Richard, Emma Bolderson & Kum Kum Khanna. (2009) Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis. Critical Reviews in Biochemistry and Molecular Biology 44:2-3, pages 98-116.
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Karen E. Sukhodolets, Alison B. Hickman, Sunita K. Agarwal, Maxim V. Sukhodolets, Victor H. Obungu, Elizabeth A. Novotny, Judy S. Crabtree, Settara C. Chandrasekharappa, Francis S. Collins, Allen M. Spiegel, A. Lee Burns & Stephen J. Marx. (2003) The 32-Kilodalton Subunit of Replication Protein A Interacts with Menin, the Product of the MEN1 Tumor Suppressor Gene. Molecular and Cellular Biology 23:2, pages 493-509.
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Gregory Rodrigo, Sophie Roumagnac, Marc S. Wold, Bernard Salles & Patrick Calsou. (2000) DNA Replication but Not Nucleotide Excision Repair Is Required for UVC-Induced Replication Protein A Phosphorylation in Mammalian Cells. Molecular and Cellular Biology 20:8, pages 2696-2705.
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Steven J. Brill & Suzanne Bastin-Shanower. (1998) Identification and Characterization of the Fourth Single-Stranded-DNA Binding Domain of Replication Protein A. Molecular and Cellular Biology 18:12, pages 7225-7234.
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Gilad Mass, Tamar Nethanel & Gabriel Kaufmann. (1998) The Middle Subunit of Replication Protein A Contacts Growing RNA-DNA Primers in Replicating Simian Virus 40 Chromosomes. Molecular and Cellular Biology 18:11, pages 6399-6407.
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Eugeni Namsaraev & Paul Berg. (1997) Characterization of Strand Exchange Activity of Yeast Rad51 Protein. Molecular and Cellular Biology 17:9, pages 5359-5368.
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Cristina Iftode & James A. Borowiec. (1997) Denaturation of the Simian Virus 40 Origin of Replication Mediated by Human Replication Protein A. Molecular and Cellular Biology 17:7, pages 3876-3883.
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Peter A. Bullock & D. T. Simmons. (1997) The Initiation of Simian Virus 40 DNA Replication In Vitro. Critical Reviews in Biochemistry and Molecular Biology 32:6, pages 503-568.
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Articles from other publishers (76)

Rositsa Dueva & George Iliakis. (2020) Replication protein A: a multifunctional protein with roles in DNA replication, repair and beyond. NAR Cancer 2:3.
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Nadejda I. Rechkunova & Olga I. Lavrik. (2020) Photoreactive DNA as a Tool to Study Replication Protein A Functioning in DNA Replication and Repair. Photochemistry and Photobiology 96:2, pages 440-449.
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Qing-Man Wang, Yan-Tao Yang, Yi-Ran Wang, Bo Gao, Xuguang Xi & Xi-Miao Hou. (2019) Human replication protein A induces dynamic changes in single-stranded DNA and RNA structures. Journal of Biological Chemistry 294:38, pages 13915-13927.
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Mark Hedglin, Mahesh Aitha & Stephen J. Benkovic. (2017) Monitoring the Retention of Human Proliferating Cell Nuclear Antigen at Primer/Template Junctions by Proteins That Bind Single-Stranded DNA. Biochemistry 56:27, pages 3415-3421.
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Anna Szambowska, Ingrid Tessmer, Piotr Prus, Bernhard Schlott, Helmut Pospiech & Frank Grosse. (2017) Cdc45-induced loading of human RPA onto single-stranded DNA. Nucleic Acids Research, pages gkw1364.
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Y. S. Krasikova, N. I. Rechkunova & O. I. Lavrik. (2016) Replication protein A as a major eukaryotic single-stranded DNA-binding protein and its role in DNA repair. Molecular Biology 50:5, pages 649-662.
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Erik A. Feldmann & Roberto Galletto. (2014) The DNA-Binding Domain of Yeast Rap1 Interacts with Double-Stranded DNA in Multiple Binding Modes. Biochemistry 53:48, pages 7471-7483.
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Justine Witosch, Eva Wolf & Naoko Mizuno. (2014) Architecture and ssDNA interaction of the Timeless-Tipin-RPA complex. Nucleic Acids Research 42:20, pages 12912-12927.
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Giuditta Illuzzi, Elise Fouquerel, Jean-Christophe Amé, Aurélia Noll, Kristina Rehmet, Heinz-Peter Nasheuer, Françoise Dantzer & Valérie Schreiber. (2014) PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress. Nucleic Acids Research 42:12, pages 7776-7792.
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Nicholas W Ashton, Emma Bolderson, Liza Cubeddu, Kenneth J O’Byrne & Derek J Richard. (2013) Human single-stranded DNA binding proteins are essential for maintaining genomic stability. BMC Molecular Biology 14:1.
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Chris A. Brosey, Chunli Yan, Susan E. Tsutakawa, William T. Heller, Robert P. Rambo, John A. Tainer, Ivaylo Ivanov & Walter J. Chazin. (2013) A new structural framework for integrating replication protein A into DNA processing machinery. Nucleic Acids Research 41:4, pages 2313-2327.
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Haitao Wang, Jiaxin Gao, Ada Hang-Heng Wong, Kangdi Hu, Wanjie Li, Yue Wang & Jianli Sang. (2013) Rfa2 is specifically dephosphorylated by Pph3 in Candida albicans . Biochemical Journal 449:3, pages 673-681.
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Soo-Hyun Yang, Ruobo Zhou, Judith Campbell, Junjie Chen, Taekjip Ha & Tanya T Paull. (2012) The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1. The EMBO Journal 32:1, pages 126-139.
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Claudio Carra, Janapriya Saha & Francis A. Cucinotta. (2011) Theoretical prediction of the binding free energy for mutants of replication protein A. Journal of Molecular Modeling 18:7, pages 3035-3049.
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Claudio Carra & Francis A. Cucinotta. (2011) Accurate prediction of the binding free energy and analysis of the mechanism of the interaction of replication protein A (RPA) with ssDNA. Journal of Molecular Modeling 18:6, pages 2761-2783.
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Aishwarya Prakash & Gloria E. O. Borgstahl. 2012. The Eukaryotic Replisome: a Guide to Protein Structure and Function. The Eukaryotic Replisome: a Guide to Protein Structure and Function 171 196 .
Kaori K. Takai, Tatsuya Kibe, Jill R. Donigian, David Frescas & Titia de Lange. (2011) Telomere Protection by TPP1/POT1 Requires Tethering to TIN2. Molecular Cell 44:4, pages 647-659.
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Giada A. Locatelli, Helmut Pospiech, Nicolas Tanguy Le Gac, Barbara van Loon, Ulrich Hubscher, Sinikka Parkkinen, Juhani E. Syväoja & Giuseppe Villani. (2010) Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase ϵ in the presence of replication protein A and proliferating-cell nuclear antigen . Biochemical Journal 429:3, pages 573-582.
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Min Huang, Jung Min Kim, Bunsyo Shiotani, Kailin Yang, Lee Zou & Alan D. D'Andrea. (2010) The FANCM/FAAP24 Complex Is Required for the DNA Interstrand Crosslink-Induced Checkpoint Response. Molecular Cell 39:2, pages 259-268.
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Sandra Broderick, Kristina Rehmet, Claire Concannon & Heinz-Peter Nasheuer. 2010. Genome Stability and Human Diseases. Genome Stability and Human Diseases 143 163 .
N.I. Rechkunova & O.I. Lavrik. 2010. Genome Stability and Human Diseases. Genome Stability and Human Diseases 251 277 .
Jonathan Eric Nuss, Deacon John Sweeney & Gerald Michael Alter. (2009) Prediction of and Experimental Support for the Three-Dimensional Structure of Replication Protein A. Biochemistry 48:33, pages 7892-7905.
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Xiaoyi Deng, Aishwarya Prakash, Kajari Dhar, Gilson S. Baia, Carol Kolar, Greg G. Oakley & Gloria E. O. Borgstahl. (2009) Human Replication Protein A−Rad52−Single-Stranded DNA Complex: Stoichiometry and Evidence for Strand Transfer Regulation by Phosphorylation. Biochemistry 48:28, pages 6633-6643.
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Chris A. Brosey, Marie-Eve Chagot, Mark Ehrhardt, Dalyir I. Pretto, Brian E. Weiner & Walter J. Chazin. (2009) NMR Analysis of the Architecture and Functional Remodeling of a Modular Multidomain Protein, RPA. Journal of the American Chemical Society 131:18, pages 6346-6347.
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Anne M. Dickson, Yulia Krasikova, Pavel Pestryakov, Olga Lavrik & Marc S. Wold. (2009) Essential functions of the 32 kDa subunit of yeast replication protein A. Nucleic Acids Research 37:7, pages 2313-2326.
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T. R. Salas, I. Petruseva, O. Lavrik & C. Saintome. (2008) Evidence for direct contact between the RPA3 subunit of the human replication protein A and single-stranded DNA. Nucleic Acids Research 37:1, pages 38-46.
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Derek J. Richard & Kum Kum Khanna. 2009. The DNA Damage Response: Implications on Cancer Formation and Treatment. The DNA Damage Response: Implications on Cancer Formation and Treatment 349 366 .
P. E. Pestryakov & O. I. Lavrik. (2009) Mechanisms of single-stranded DNA-binding protein functioning in cellular DNA metabolism. Biochemistry (Moscow) 73:13, pages 1388-1404.
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Sara K. Binz & Marc S. Wold. (2008) Regulatory Functions of the N-terminal Domain of the 70-kDa Subunit of Replication Protein A (RPA). Journal of Biological Chemistry 283:31, pages 21559-21570.
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Victor S. Mikhailov, Adam L. Vanarsdall & George F. Rohrmann. (2008) Isolation and characterization of the DNA-binding protein (DBP) of the Autographa californica multiple nucleopolyhedrovirus. Virology 370:2, pages 415-429.
Crossref
Lijie Men, Marina Roginskaya, Yue Zou & Yinsheng Wang. (2007) Redox-dependent formation of disulfide bonds in human replication protein A. Rapid Communications in Mass Spectrometry 21:16, pages 2743-2749.
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Xiaohua Jiang, Vitaly Klimovich, Alphonse I Arunkumar, Erik B Hysinger, Yingda Wang, Robert D Ott, Gulfem D Guler, Brian Weiner, Walter J Chazin & Ellen Fanning. (2006) Structural mechanism of RPA loading on DNA during activation of a simple pre-replication complex. The EMBO Journal 25:23, pages 5516-5526.
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Tonatiuh Romero Salas, Irina Petruseva, Olga Lavrik, Anne Bourdoncle, Jean-Louis Mergny, Alain Favre & Carole Saintomé. (2006) Human replication protein A unfolds telomeric G-quadruplexes. Nucleic Acids Research 34:17, pages 4857-4865.
Crossref
Shuangli Guo, Yanbin Zhang, Fenghua Yuan, Yin Gao, Liya Gu, Isaac Wong & Guo-Min Li. (2006) Regulation of Replication Protein A Functions in DNA Mismatch Repair by Phosphorylation. Journal of Biological Chemistry 281:31, pages 21607-21616.
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Yue Zou, Yiyong Liu, Xiaoming Wu & Steven M. Shell. (2006) Functions of human replication protein A (RPA): From DNA replication to DNA damage and stress responses. Journal of Cellular Physiology 208:2, pages 267-273.
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Victor S. Mikhailov, Kazuhiro Okano & George F. Rohrmann. (2006) Structural and functional analysis of the baculovirus single-stranded DNA-binding protein LEF-3. Virology 346:2, pages 469-478.
Crossref
Ludovic C. J. Gillet & Orlando D. Schärer. (2005) Molecular Mechanisms of Mammalian Global Genome Nucleotide Excision Repair. Chemical Reviews 106:2, pages 253-276.
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Yoshizumi Ishino, Tatsuya Nishino & Kosuke Morikawa. (2005) Mechanisms of Maintaining Genetic Stability by Homologous Recombination. Chemical Reviews 106:2, pages 324-339.
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Toyotaka Ishibashi, Seisuke Kimura & Kengo Sakaguchi. (2006) A Higher Plant Has Three Different Types of RPA Heterotrimeric Complex. The Journal of Biochemistry 139:1, pages 99-104.
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Xiaoming WuZhengguan YangYiyong LiuYue Zou. (2005) Preferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damage. Biochemical Journal 391:3, pages 473-480.
Crossref
Victor S. Mikhailov, Kazuhiro Okano & George F. Rohrmann. (2005) The Redox State of the Baculovirus Single-stranded DNA-binding Protein LEF-3 Regulates Its DNA Binding, Unwinding, and Annealing Activities. Journal of Biological Chemistry 280:33, pages 29444-29453.
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Jacob G. Robison, Lu Lu, Kathleen Dixon & John J. Bissler. (2005) DNA Lesion-specific Co-localization of the Mre11/Rad50/Nbs1 (MRN) Complex and Replication Protein A (RPA) to Repair Foci. Journal of Biological Chemistry 280:13, pages 12927-12934.
Crossref
Alphonse I Arunkumar, Vitaly Klimovich, Xiaohua Jiang, Robert D Ott, L Mizoue, Ellen Fanning & Walter J Chazin. (2005) Insights into hRPA32 C-terminal domain–mediated assembly of the simian virus 40 replisome. Nature Structural & Molecular Biology 12:4, pages 332-339.
Crossref
Sara K. Binz, Anne M. Sheehan & Marc S. Wold. (2004) Replication Protein A phosphorylation and the cellular response to DNA damage. DNA Repair 3:8-9, pages 1015-1024.
Crossref
Amy J. Bartrand, Dagmawi Iyasu & George S. Brush. (2004) DNA Stimulates Mec1-mediated Phosphorylation of Replication Protein A. Journal of Biological Chemistry 279:25, pages 26762-26767.
Crossref
Jonathan E. Nuss & Gerald M. Alter. (2004) Denaturation of replication protein A reveals an alternative conformation with intact domain structure and oligonucleotide binding activity. Protein Science 13:5, pages 1365-1378.
Crossref
Yueh-Ming Loo & Thomas Melendy. (2004) Recruitment of Replication Protein A by the Papillomavirus E1 Protein and Modulation by Single-Stranded DNA. Journal of Virology 78:4, pages 1605-1615.
Crossref
Alexey Bochkarev & Elena Bochkareva. (2004) From RPA to BRCA2: lessons from single-stranded DNA binding by the OB-fold. Current Opinion in Structural Biology 14:1, pages 36-42.
Crossref
Gabriel Kaufmann & Tamar Nethanel. 2004. Progress in Nucleic Acid Research and Molecular Biology Volume 77. Progress in Nucleic Acid Research and Molecular Biology Volume 77 173 209 .
Susan L. Uprichard & David M. Knipe. (2003) Conformational Changes in the Herpes Simplex Virus ICP8 DNA-Binding Protein Coincident with Assembly in Viral Replication Structures. Journal of Virology 77:13, pages 7467-7476.
Crossref
Pavel E. Pestryakov, Klaus Weisshart, Bernhard Schlott, Svetlana N. Khodyreva, Elisabeth Kremmer, Frank Grosse, Olga I. Lavrik & Heinz-Peter Nasheuer. (2003) Human Replication Protein A. Journal of Biological Chemistry 278:19, pages 17515-17524.
Crossref
Doba Jackson, Kajari Dhar, James K Wahl, Marc S Wold & Gloria E.O Borgstahl. (2002) Analysis of the Human Replication Protein A:Rad52 Complex: Evidence for Crosstalk Between RPA32, RPA70, Rad52 and DNA. Journal of Molecular Biology 321:1, pages 133-148.
Crossref
Hans-Jörg Riedinger, Maria van Betteraey-Nikoleit & Hans Probst. (2002) Re-oxygenation of hypoxic simian virus 40 (SV40)-infected CV1 cells causes distinct changes of SV40 minichromosome-associated replication proteins. European Journal of Biochemistry 269:9, pages 2383-2393.
Crossref
Kathleen C. Dudas, Sarah K. Scouten & William T. Ruyechan. (2001) Conformational Change in the Herpes Simplex Single-Strand Binding Protein Induced by DNA. Biochemical and Biophysical Research Communications 288:1, pages 184-190.
Crossref
Paola Grandi, Michail Eltsov, Inga Nielsen & Ivan Raška. (2001) DNA double-strand breaks induce formation of RP-A/Ku foci on in vitro reconstituted Xenopus sperm nuclei . Journal of Cell Science 114:18, pages 3345-3357.
Crossref
Suzanne A. Bastin-Shanower & Steven J. Brill. (2001) Functional Analysis of the Four DNA Binding Domains of Replication Protein A. Journal of Biological Chemistry 276:39, pages 36446-36453.
Crossref
Carmen Eckerich, Frank O. Fackelmayer & Rolf Knippers. (2001) Zinc affects the conformation of nucleoprotein filaments formed by replication protein A (RPA) and long natural DNA molecules. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1538:1, pages 67-75.
Crossref
Marina Mapelli, Martin Mühleisen, Giorgia Persico, Hans van der Zandt & Paul A. Tucker. (2000) The 60-Residue C-Terminal Region of the Single-Stranded DNA Binding Protein of Herpes Simplex Virus Type 1 Is Required for Cooperative DNA Binding. Journal of Virology 74:19, pages 8812-8822.
Crossref
Elena Bochkareva, Sergey Korolev & Alexey Bochkarev. (2000) The Role for Zinc in Replication Protein A. Journal of Biological Chemistry 275:35, pages 27332-27338.
Crossref
Yaron Daniely & James A. Borowiec. (2000) Formation of a Complex between Nucleolin and Replication Protein a after Cell Stress Prevents Initiation of DNA Replication. The Journal of Cell Biology 149:4, pages 799-810.
Crossref
G. MER, A. BOCHKAREV, W.J. CHAZIN & A.M. EDWARDS. (2000) Three-dimensional Structure and Function of Replication Protein A. Cold Spring Harbor Symposia on Quantitative Biology 65:0, pages 193-200.
Crossref
O. I. Lavrik, D. M. Kolpashchikov, K. Weisshart, H.-P. Nasheuer, S. N. Khodyreva & A. Favre. (1999) RPA subunit arrangement near the 3'-end of the primer is modulated by the length of the template strand and cooperative protein interactions. Nucleic Acids Research 27:21, pages 4235-4240.
Crossref
U. Schweizer, T. Hey, G. Lipps & G. Krauss. (1999) Photocrosslinking locates a binding site for the large subunit of human replication protein A to the damaged strand of cisplatin-modified DNA. Nucleic Acids Research 27:15, pages 3183-3189.
Crossref
Kurt W. Kohn. (1999) Molecular Interaction Map of the Mammalian Cell Cycle Control and DNA Repair Systems. Molecular Biology of the Cell 10:8, pages 2703-2734.
Crossref
Kai Treuner, Marco Findeisen, Ulrich Strausfeld & Rolf Knippers. (1999) Phosphorylation of Replication Protein A Middle Subunit (RPA32) Leads to a Disassembly of the RPA Heterotrimer. Journal of Biological Chemistry 274:22, pages 15556-15561.
Crossref
O.I. Lavrik, D.M. Kolpashchikov, H.-P. Nasheuer, K. Weisshart & A. Favre. (1998) Alternative conformations of human replication protein A are detected by crosslinks with primers carrying a photoreactive group at the 3′-end. FEBS Letters 441:2, pages 186-190.
Crossref
Kai Treuner, Carmen Eckerich & Rolf Knippers. (1998) Chromatin Association of Replication Protein A. Journal of Biological Chemistry 273:48, pages 31744-31750.
Crossref
Wouter L. de Laat, Esther Appeldoorn, Kaoru Sugasawa, Eric Weterings, Nicolaas G.J. Jaspers & Jan H.J. Hoeijmakers. (1998) DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair. Genes & Development 12:16, pages 2598-2609.
Crossref
Elena Bochkareva, Lori Frappier, Aled M. Edwards & Alexey Bochkarev. (1998) The RPA32 Subunit of Human Replication Protein A Contains a Single-stranded DNA-binding Domain. Journal of Biological Chemistry 273:7, pages 3932-3936.
Crossref
O. I. Lavrik, H.-P. Nasheuer, K. Weisshart, M. S. Wold, R. Prasad, W. A. Beard, S. H. Wilson & A. Favre. (1998) Subunits of human replication protein A are crosslinked by photoreactive primers synthesized by DNA polymerases. Nucleic Acids Research 26:2, pages 602-607.
Crossref
Joseph S. Wall, Martha N. Simon & James F. Hainfeld. (2020) The BNL STEM Facility. Microscopy and Microanalysis 3:S2, pages 277-278.
Crossref
Marc S. Wold. (1997) REPLICATION PROTEIN A: A Heterotrimeric, Single-Stranded DNA-Binding Protein Required for Eukaryotic DNA Metabolism. Annual Review of Biochemistry 66:1, pages 61-92.
Crossref
Jack D Griffith, Suman Lee & Yuh-Hwa Wang. (1997) Visualizing nucleic acids and their complexes using electron microscopy. Current Opinion in Structural Biology 7:3, pages 362-366.
Crossref
Hongwu Niu, Hediye Erdjument-Bromage, Zhen-Qiang Pan, Suk-Hee Lee, Paul Tempst & Jerard Hurwitz. (1997) Mapping of Amino Acid Residues in the p34 Subunit of Human Single-stranded DNA-binding Protein Phosphorylated by DNA-dependent Protein Kinase and Cdc2 Kinase in Vitro. Journal of Biological Chemistry 272:19, pages 12634-12641.
Crossref
Alexey Bochkarev, Richard A. Pfuetzner, Aled M. Edwards & Lori Frappier. (1997) Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA. Nature 385:6612, pages 176-181.
Crossref
Joseph S. Wall, James F. Hainfeld & Martha N. Simon. 1997. Nuclear Structure and Function. Nuclear Structure and Function 139 164 .

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