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Molecular and Cellular Biology Volume 16, 1996 - Issue 9
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Research Article

A Mutant p53 That Discriminates between p53-Responsive Genes Cannot Induce Apoptosis

P. Friedlander1 Department of Biological Sciences, Columbia University, New York, New York10027
,
Y. Haupt2 Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
,
C. Prives1 Department of Biological Sciences, Columbia University, New York, New York10027
&
M. Oren2 Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
Pages 4961-4971 | Received 12 Mar 1996, Accepted 03 Jun 1996, Published online: 29 Mar 2023

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Peihong Ma, Maureen Magut, XinBin Chen & Chang-Yan Chen. (2002) p53 Is Necessary for the Apoptotic Response Mediated by a Transient Increase of Ras Activity. Molecular and Cellular Biology 22:9, pages 2928-2938.
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Jianhui Zhu & Xinbin Chen. (2000) MCG10, a Novel p53 Target Gene That Encodes a KH Domain RNA-Binding Protein, Is Capable of Inducing Apoptosis and Cell Cycle Arrest in G2-M. Molecular and Cellular Biology 20:15, pages 5602-5618.
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Oscar N. Aurelio, Xiao-Tang Kong, Swati Gupta & Eric J. Stanbridge. (2000) p53 Mutants Have Selective Dominant-Negative Effects on Apoptosis but Not Growth Arrest in Human Cancer Cell Lines. Molecular and Cellular Biology 20:3, pages 770-778.
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Indira Unnikrishnan, Arash Radfar, Jenia Jenab-Wolcott & Naomi Rosenberg. (1999) p53 Mediates Apoptotic Crisis in Primary Abelson Virus-Transformed Pre-B Cells. Molecular and Cellular Biology 19:7, pages 4825-4831.
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Wilma T. Steegenga, Avi Shvarts, Nicole Riteco, Johannes L. Bos & Aart G. Jochemsen. (1999) Distinct Regulation of p53 and p73 Activity by Adenovirus E1A, E1B, and E4orf6 Proteins. Molecular and Cellular Biology 19:5, pages 3885-3894.
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Margaret Ashcroft, Michael H. G. Kubbutat & Karen H. Vousden. (1999) Regulation of p53 Function and Stability by Phosphorylation. Molecular and Cellular Biology 19:3, pages 1751-1758.
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Charles J. Di Como, Christian Gaiddon & Carol Prives. (1999) p73 Function Is Inhibited by Tumor-Derived p53 Mutants in Mammalian Cells. Molecular and Cellular Biology 19:2, pages 1438-1449.
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Kevin M. Ryan & Karen H. Vousden. (1998) Characterization of Structural p53 Mutants Which Show Selective Defects in Apoptosis but Not Cell Cycle Arrest. Molecular and Cellular Biology 18:7, pages 3692-3698.
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Robert L. Ludwig, Stewart Bates & Karen H. Vousden. (1996) Differential Activation of Target Cellular Promoters by p53 Mutants with Impaired Apoptotic Function. Molecular and Cellular Biology 16:9, pages 4952-4960.
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