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Molecular and Cellular Biology Volume 17, 1997 - Issue 12
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Research Article

U1 Small Nuclear RNA-Promoted Exon Selection Requires a Minimal Distance between the Position of U1 Binding and the 3′ Splice Site across the Exon

Dong-Youn HwangDepartment of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania15261
&
Justus B. CohenDepartment of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania15261Correspondence[email protected]
Pages 7099-7107 | Received 25 Jul 1997, Accepted 04 Sep 1997, Published online: 29 Mar 2023

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Wuh-Liang Hwu, Yu-May Lee & Ni-Chung Lee. (2017) Gene therapy with modified U1 small nuclear RNA. Expert Review of Endocrinology & Metabolism 12:3, pages 171-175.
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William G. Fairbrother & Lawrence A. Chasin. (2000) Human Genomic Sequences That Inhibit Splicing. Molecular and Cellular Biology 20:18, pages 6816-6825.
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Articles from other publishers (21)

Samuel T. Hatch, Aaron A. Smargon & Gene W. Yeo. (2022) Engineered U1 snRNAs to modulate alternatively spliced exons. Methods 205, pages 140-148.
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Andrew M Jobbins, Sébastien Campagne, Robert Weinmeister, Christian M Lucas, Alison R Gosliga, Antoine Clery, Li Chen, Lucy P Eperon, Mark J Hodson, Andrew J Hudson, Frédéric H T Allain & Ian C Eperon. (2021) Exon‐independent recruitment of SRSF1 is mediated by U1 snRNP stem‐loop 3. The EMBO Journal 41:1.
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Gabriela Giannina Schäfer, Lukas Jörg Grebe, Robin Schinkel & Bernhard Lieb. (2021) The Evolution of Hemocyanin Genes in Caenogastropoda: Gene Duplications and Intron Accumulation in Highly Diverse Gastropods. Journal of Molecular Evolution 89:9-10, pages 639-655.
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Eun-Chae Kwon, Jong-Hwa Kim & Nam-Soo Kim. (2020) Comprehensive genomic analyses with 115 plastomes from algae to seed plants: structure, gene contents, GC contents, and introns. Genes & Genomics 42:5, pages 553-570.
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Melina Mathur, Cameron M. Kim, Sarah A. Munro, Shireen S. Rudina, Eric M. Sawyer & Christina D. Smolke. (2019) Programmable mutually exclusive alternative splicing for generating RNA and protein diversity. Nature Communications 10:1.
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Maria Francisca Coutinho, Liliana Matos, Juliana Inês Santos & Sandra Alves. 2019. The mRNA Metabolism in Human Disease. The mRNA Metabolism in Human Disease 133 177 .
Natalia N. Singh, José Bruno Del Rio-Malewski, Diou Luo, Eric W. Ottesen, Matthew D. Howell & Ravindra N. Singh. (2017) Activation of a cryptic 5′ splice site reverses the impact of pathogenic splice site mutations in the spinal muscular atrophy gene. Nucleic Acids Research 45:21, pages 12214-12240.
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Lei Guo & Chun-Ming Liu. (2015) A single-nucleotide exon found in Arabidopsis. Scientific Reports 5:1.
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Mauricio A. Arias, Ashira Lubkin & Lawrence A. Chasin. (2015) Splicing of designer exons informs a biophysical model for exon definition. RNA 21:2, pages 213-229.
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Janne J. Turunen, Bhupendra Verma, Tuula A. Nyman & Mikko J. Frilander. (2013) HnRNPH1/H2, U1 snRNP, and U11 snRNP cooperate to regulate the stability of the U11-48K pre-mRNA . RNA 19:3, pages 380-389.
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Eliseos J. Mucaki, Ben C. Shirley & Peter K. Rogan. (2013) Prediction of Mutant mRNA Splice Isoforms by Information Theory-Based Exon Definition. Human Mutation, pages n/a-n/a.
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Eugenio Fernandez Alanis, Mirko Pinotti, Andrea Dal Mas, Dario Balestra, Nicola Cavallari, Malgorzata E. Rogalska, Francesco Bernardi & Franco Pagani. (2012) An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects. Human Molecular Genetics 21:11, pages 2389-2398.
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Alexander Churbanov, Igor Vořechovský & Chindo Hicks. (2010) A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements. BMC Bioinformatics 11:1.
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Xiang H.-F. Zhang, Mauricio A. Arias, Shengdong Ke & Lawrence A. Chasin. (2009) Splicing of designer exons reveals unexpected complexity in pre-mRNA splicing. RNA 15:3, pages 367-376.
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Scott William Roy & Manuel Irimia. (2009) Mystery of intron gain: new data and new models. Trends in Genetics 25:2, pages 67-73.
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Veiko Krauss, Christian Thümmler, Franziska Georgi, Jörg Lehmann, Peter F. Stadler & Carina Eisenhardt. (2008) Near Intron Positions Are Reliable Phylogenetic Markers: An Application to Holometabolous Insects. Molecular Biology and Evolution 25:5, pages 821-830.
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Keren Borensztajn, Marie-Laure Sobrier, Philippe Duquesnoy, Anne-Marie Fischer, Jacqueline Tapon-Bretaudière & Serge Amselem. (2006) Oriented Scanning Is the Leading Mechanism Underlying 5′ Splice Site Selection in Mammals. PLoS Genetics 2:9, pages e138.
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Veiko Krauss, Marek Pecyna, Katrin Kurz & Heinz Sass. (2005) Phylogenetic Mapping of Intron Positions: A Case Study of Translation Initiation Factor eIF2γ. Molecular Biology and Evolution 22:1, pages 74-84.
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Susan E Ptak & Dmitri A Petrov. (2002) How Intron Splicing Affects the Deletion and Insertion Profile in Drosophila melanogaster . Genetics 162:3, pages 1233-1244.
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Franco Pagani, Emanuele Buratti, Cristiana Stuani, Regina Bendix, Thilo Dörk & Francisco E. Baralle. (2002) A new type of mutation causes a splicing defect in ATM. Nature Genetics 30:4, pages 426-429.
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Zhi-An Yuan, Enhong Chen & Carolyn W. Gibson. (2001) Model System for Evaluation of Alternative Splicing: Exon Skipping. DNA and Cell Biology 20:12, pages 807-813.
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