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Molecular and Cellular Biology Volume 17, 1997 - Issue 8
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Research Article

Requirement of Phosphatidylinositol 3-Kinase-Dependent Pathway and Src for Gas6-Axl Mitogenic and Survival Activities in NIH 3T3 Fibroblasts

Sandro GoruppiLaboratorio Nazionale Consorzio Interuniversitario Biotecnologie, Italy Amgen, Thousand Oaks, California
,
Elisabetta RuaroLaboratorio Nazionale Consorzio Interuniversitario Biotecnologie, Italy Amgen, Thousand Oaks, California;International Centre for Genetic Engineering and Biotechnology, Italy Amgen, Thousand Oaks, California
,
Brian VarnumPadriciano, Trieste, Italy Amgen, Thousand Oaks, California
&
Claudio SchneiderLaboratorio Nazionale Consorzio Interuniversitario Biotecnologie, Italy Amgen, Thousand Oaks, California;Dipartimento di Scienze e Tecnologie Biomediche, Università degli Studi di Udine, Udine, Italy Amgen, Thousand Oaks, CaliforniaCorrespondence[email protected]
Pages 4442-4453 | Received 28 Jan 1997, Accepted 29 Apr 1997, Published online: 29 Mar 2023

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Ross A Okimoto & Trever G Bivona. (2015) AXL receptor tyrosine kinase as a therapeutic target in NSCLC. Lung Cancer: Targets and Therapy 6, pages 27-34.
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Kinga Pénzes, Christine Baumann, István Szabadkai, László Őrfi, György Kéri, Axel Ullrich & Robert Torka. (2014) Combined inhibition of AXL, Lyn and p130Cas kinases block migration of triple negative breast cancer cells. Cancer Biology & Therapy 15:11, pages 1571-1582.
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Vadim Budagian, Elena Bulanova, Zane Orinska, Erwin Duitman, Katja Brandt, Andreas Ludwig, Dieter Hartmann, Greg Lemke, Paul Saftig & Silvia Bulfone-Paus. (2005) Soluble Axl Is Generated by ADAM10-Dependent Cleavage and Associates with Gas6 in Mouse Serum. Molecular and Cellular Biology 25:21, pages 9324-9339.
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Sandro Goruppi, Cristina Chiaruttini, Maria Elisabetta Ruaro, Brian Varnum & Claudio Schneider. (2001) Gas6 Induces Growth, β-Catenin Stabilization, and T-Cell Factor Transcriptional Activation in Contact-Inhibited C57 Mammary Cells. Molecular and Cellular Biology 21:3, pages 902-915.
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Wei-Ping Lee, Yong Liao, Dan Robinson, Hsing-Jien Kung, Edison T. Liu & Mien-Chie Hung. (1999) Axl-Gas6 Interaction Counteracts E1A-Mediated Cell Growth Suppression and Proapoptotic Activity. Molecular and Cellular Biology 19:12, pages 8075-8082.
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Daniel Besser, Jacqueline F. Bromberg, James E. Darnell$suffix/text()$suffix/text() & Hidesaburo Hanafusa. (1999) A Single Amino Acid Substitution in the v-Eyk Intracellular Domain Results in Activation of Stat3 and Enhances Cellular Transformation. Molecular and Cellular Biology 19:2, pages 1401-1409.
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Maria-Magdalena Georgescu, Kathrin H. Kirsch, Tomoyuki Shishido, Chen Zong & Hidesaburo Hanafusa. (1999) Biological Effects of c-Mer Receptor Tyrosine Kinase in Hematopoietic Cells Depend on the Grb2 Binding Site in the Receptor and Activation of NF-κB. Molecular and Cellular Biology 19:2, pages 1171-1181.
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