Citations (166)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (6)
Jinsheng Dong, Ruby Lai, Jennifer L. Jennings, Andrew J. Link & Alan G. Hinnebusch. (2005) The Novel ATP-Binding Cassette Protein ARB1 Is a Shuttling Factor That Stimulates 40S and 60S Ribosome Biogenesis. Molecular and Cellular Biology 25:22, pages 9859-9873.
Read now
Read now
Joy Sturtevant. (2002) Translation elongation-3-like factors: are they rational antifungal targets?. Expert Opinion on Therapeutic Targets 6:5, pages 545-553.
Read now
Read now
Edith Gomez & Graham D. Pavitt. (2000) Identification of Domains and Residues within the ɛ Subunit of Eukaryotic Translation Initiation Factor 2B (eIF2Bɛ) Required for Guanine Nucleotide Exchange Reveals a Novel Activation Function Promoted by eIF2B Complex Formation. Molecular and Cellular Biology 20:11, pages 3965-3976.
Read now
Read now
Ruojing Yang, Sheree A. Wek & Ronald C. Wek. (2000) Glucose Limitation Induces GCN4 Translation by Activation of Gcn2 Protein Kinase. Molecular and Cellular Biology 20:8, pages 2706-2717.
Read now
Read now
Hongfang Qiu, Cuihua Hu, James Anderson, Glenn R. Björk, Srimonti Sarkar, Anita K. Hopper & Alan G. Hinnebusch. (2000) Defects in tRNA Processing and Nuclear Export Induce GCN4 Translation Independently of Phosphorylation of the α Subunit of Eukaryotic Translation Initiation Factor 2. Molecular and Cellular Biology 20:7, pages 2505-2516.
Read now
Read now
Hongfang Qiu, Minerva T. Garcia-Barrio & Alan G. Hinnebusch. (1998) Dimerization by Translation Initiation Factor 2 Kinase GCN2 Is Mediated by Interactions in the C-Terminal Ribosome-Binding Region and the Protein Kinase Domain. Molecular and Cellular Biology 18:5, pages 2697-2711.
Read now
Read now
Articles from other publishers (160)
Hanchen Chen, Ting Pan, Xueao Zheng, Yongchi Huang, Chong Wu, Tongbin Yang, Shan Gao, Lili Wang & Shunping Yan. (2023) The ATR–WEE1 kinase module promotes SUPPRESSOR OF GAMMA RESPONSE 1 translation to activate replication stress responses. The Plant Cell 35:8, pages 3021-3034.
Crossref
Crossref
Ronald C. Wek, Tracy G. AnthonyKirk A. Staschke. (2023) Surviving and Adapting to Stress: Translational Control and the Integrated Stress Response. Antioxidants & Redox Signaling 39:4-6, pages 351-373.
Crossref
Crossref
İrem Uluisik Yilmaz & Ahmet Koc. (2023) Boron Stress Signal is Transmitted Through the TOR Pathway. Journal of Trace Elements in Medicine and Biology, pages 127222.
Crossref
Crossref
Kenneth R. Carlson, Millie M. Georgiadis, Feven Tameire, Kirk A. Staschke & Ronald C. Wek. (2023) Activation of Gcn2 by small molecules designed to be inhibitors. Journal of Biological Chemistry 299:4, pages 104595.
Crossref
Crossref
Susanne Gottfried, Siaosi M. B. M. J. Koloamatangi, Clement Daube, Anja H. Schiemann & Evelyn Sattlegger. (2022) A genetic approach to identify amino acids in Gcn1 required for Gcn2 activation. PLOS ONE 17:11, pages e0277648.
Crossref
Crossref
Matthew Pinch, Theodore Muka, Yashoda Kandel, Mahesh Lamsal, Nathan Martinez, Marialuisa Teixeira, Dmitri Y. Boudko & Immo A. Hansen. (2022) General control nonderepressible 1 interacts with cationic amino acid transporter 1 and affects Aedes aegypti fecundity. Parasites & Vectors 15:1.
Crossref
Crossref
Michael Dean, Karobi Moitra & Rando Allikmets. (2022) The human ATP‐binding cassette (ABC) transporter superfamily. Human Mutation 43:9, pages 1162-1182.
Crossref
Crossref
Ansul Lokdarshi & Albrecht G. von Arnim. (2022) Review: Emerging roles of the signaling network of the protein kinase GCN2 in the plant stress response. Plant Science 320, pages 111280.
Crossref
Crossref
Feng Ding, Bing-Lei Zhang, Fan Li, Ying-Rui Li, Jian-Hui Li & Ying-Tang Lu. (2022) General control non-repressible 20 functions in the salt stress response of Arabidopsis seedling by modulating ABA accumulation. Environmental and Experimental Botany 198, pages 104856.
Crossref
Crossref
Robert A Crawford, Mark P Ashe, Simon J Hubbard & Graham D Pavitt. (2022) Cytosolic aspartate aminotransferase moonlights as a ribosome-binding modulator of Gcn2 activity during oxidative stress. eLife 11.
Crossref
Crossref
Lisa Houston, Evan M. Platten, Sara M. Connelly, Jiyu Wang & Elizabeth J. Grayhack. (2022) Frameshifting at collided ribosomes is modulated by elongation factor eEF3 and by integrated stress response regulators Gcn1 and Gcn20. RNA 28:3, pages 320-339.
Crossref
Crossref
Colin P. Tang, Owen Clark, John R. Ferrarone, Carl Campos, Alshad S. Lalani, John D. Chodera, Andrew M. Intlekofer, Olivier Elemento & Ingo K. Mellinghoff. (2021) GCN2 kinase activation by ATP-competitive kinase inhibitors. Nature Chemical Biology 18:2, pages 207-215.
Crossref
Crossref
Kyusik Q. Kim & Hani S. Zaher. (2022) Canary in a coal mine: collided ribosomes as sensors of cellular conditions. Trends in Biochemical Sciences 47:1, pages 82-97.
Crossref
Crossref
Li Yan, Jianhong Zhang, Hongyu Chen & Hongmei Luo. (2021) Genome-wide analysis of ATP-binding cassette transporter provides insight to genes related to bioactive metabolite transportation in Salvia miltiorrhiza. BMC Genomics 22:1.
Crossref
Crossref
I. Faus, R. Niñoles, V. Kesari & J. Gadea. (2021) The ABCF3 Gene of Arabidopsis Is Functionally Linked with GCN1 but Not with GCN2 During Stress and Development. Plant Molecular Biology Reporter 39:4, pages 663-672.
Crossref
Crossref
Christian A. E. Westrip, Qinqin Zhuang, Charlotte Hall, Charlotte D. Eaton & Mathew L. Coleman. (2021) Developmentally regulated GTPases: structure, function and roles in disease. Cellular and Molecular Life Sciences 78:23, pages 7219-7235.
Crossref
Crossref
Agnieszka A. PochopienBertrand Beckert, Sergo Kasvandik, Otto Berninghausen, Roland Beckmann, Tanel Tenson & Daniel N. Wilson. (2021) Structure of Gcn1 bound to stalled and colliding 80S ribosomes. Proceedings of the National Academy of Sciences 118:14.
Crossref
Crossref
Corentin R. Fostier, Laura Monlezun, Farès Ousalem, Shikha Singh, John F. Hunt & Grégory Boël. (2020) ABC‐F translation factors: from antibiotic resistance to immune response. FEBS Letters 595:6, pages 675-706.
Crossref
Crossref
Liewei L. Yan & Hani S. Zaher. (2021) Ribosome quality control antagonizes the activation of the integrated stress response on colliding ribosomes. Molecular Cell 81:3, pages 614-628.e4.
Crossref
Crossref
Sezen Meydan & Nicholas R. Guydosh. (2020) A cellular handbook for collided ribosomes: surveillance pathways and collision types. Current Genetics 67:1, pages 19-26.
Crossref
Crossref
Elena Harjes, Geoffrey B. Jameson, Yi‐Hsuan Tu, Natalie Burr, Trevor S. Loo, Alexander K. Goroncy, Patrick J.B. Edwards, Stefan Harjes, Ben Munro, Christoph Göbl, Evelyn Sattlegger & Gillian E. Norris. (2020) Experimentally based structural model of Yih1 provides insight into its function in controlling the key translational regulator Gcn2. FEBS Letters 595:3, pages 324-340.
Crossref
Crossref
Mahin Haque, Gulzar Ahmed Rather, Ehraz Mehmood Siddiqui, Sadaf Jahan, Andleeb Khan, Hafiz Antar Makeen, Athanasios Alexiou & Ghulam Md Ashraf. 2021. Autism Spectrum Disorder and Alzheimer's Disease. Autism Spectrum Disorder and Alzheimer's Disease
239
281
.
Janaina Figueira-Mansur, Carlos G. Schrago, Tiago S. Salles, Evelyn S. L. Alvarenga, Brenda M. Vasconcellos, Ana Claudia A. Melo & Monica F. Moreira. (2020) Phylogenetic analysis of the ATP-binding cassette proteins suggests a new ABC protein subfamily J in Aedes aegypti (Diptera: Culicidae). BMC Genomics 21:1.
Crossref
Crossref
Mengyun Shi, Shuaishuai Wang, Yang Zhang, Shen Wang, Jing Zhao, Huan Feng, Peipei Sun, Congbing Fang & Xingbin Xie. (2020) Genome-wide characterization and expression analysis of ATP-binding cassette (ABC) transporters in strawberry reveal the role of FvABCC11 in cadmium tolerance. Scientia Horticulturae 271, pages 109464.
Crossref
Crossref
Thareendra De Zoysa & Eric M. Phizicky. (2020) Hypomodified tRNA in evolutionarily distant yeasts can trigger rapid tRNA decay to activate the general amino acid control response, but with different consequences. PLOS Genetics 16:8, pages e1008893.
Crossref
Crossref
Sezen Meydan & Nicholas R. Guydosh. (2020) Disome and Trisome Profiling Reveal Genome-wide Targets of Ribosome Quality Control. Molecular Cell 79:4, pages 588-602.e6.
Crossref
Crossref
Mónica A. Mechoud, Nuria Pujol-Carrion, Sandra Montella-Manuel & Maria Angeles de la Torre-Ruiz. (2020) Interactions of GMP with Human Glrx3 and with Saccharomyces cerevisiae Grx3 and Grx4 Converge in the Regulation of the Gcn2 Pathway. Applied and Environmental Microbiology 86:14.
Crossref
Crossref
Colin Chih-Chien Wu, Amy Peterson, Boris Zinshteyn, Sergi Regot & Rachel Green. (2020) Ribosome Collisions Trigger General Stress Responses to Regulate Cell Fate. Cell 182:2, pages 404-416.e14.
Crossref
Crossref
Rashmi Ramesh & Evelyn Sattlegger. (2020) Domain II of the translation elongation factor eEF1A is required for Gcn2 kinase inhibition. FEBS Letters 594:14, pages 2266-2281.
Crossref
Crossref
Sydney Skuodas, Amy Clemons, Michael Hayes, Ashley Goll, Betul Zora, Daniel L. Weeks, Bryan T. Phillips & Jan S. Fassler. (2020) The ABCF gene family facilitates disaggregation during animal development. Molecular Biology of the Cell 31:13, pages 1324-1345.
Crossref
Crossref
Yeonjin KimMark S. Sundrud, Changqian ZhouMaja EdeniusDavide ZoccoKristen Powers, Miao ZhangRalph Mazitschek, Anjana Rao, Chang-Yeol YeoErika H. Noss, Michael B. BrennerMalcolm Whitman & Tracy L. Keller. (2020) Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells. Proceedings of the National Academy of Sciences 117:16, pages 8900-8911.
Crossref
Crossref
Zain Akram, Ishtiaq Ahmed, Heike Mack, Ramandeep Kaur, Richard C. Silva, Beatriz A. Castilho, Sylvie Friant, Evelyn Sattlegger & Alan L. Munn. (2020) Yeast as a Model to Understand Actin-Mediated Cellular Functions in Mammals—Illustrated with Four Actin Cytoskeleton Proteins. Cells 9:3, pages 672.
Crossref
Crossref
Antonia María Romero, Lucía Ramos-Alonso, Paula Alepuz, Sergi Puig & María Teresa Martínez-Pastor. (2020) Global translational repression induced by iron deficiency in yeast depends on the Gcn2/eIF2α pathway. Scientific Reports 10:1.
Crossref
Crossref
Heather P Harding, Adriana Ordonez, Felicity Allen, Leopold Parts, Alison J Inglis, Roger L Williams & David Ron. (2019) The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells. eLife 8.
Crossref
Crossref
Yingchen Hao, Yongxia Yang, Songjie Zhang, Yibo Li, Chunhe Zhai, Yue Long, Hongfang Jia & Songtao Zhang. (2019) Expression, purification, and in vitro characterization of kinase domain of NtGCN2 from tobacco. Protein Expression and Purification 163, pages 105452.
Crossref
Crossref
Glenn R. Masson. (2019) Towards a model of GCN2 activation. Biochemical Society Transactions 47:5, pages 1481-1488.
Crossref
Crossref
Elizabeth Peterson, Emma Shippee, Margo A. Brinton & Parjit Kaur. (2019) Biochemical characterization of the mouse ABCF3 protein, a partner of the flavivirus-resistance protein OAS1B. Journal of Biological Chemistry 294:41, pages 14937-14952.
Crossref
Crossref
Xiaoyu Liu, Taiaba Afrin & Karolina M. Pajerowska-Mukhtar. (2019) Arabidopsis GCN2 kinase contributes to ABA homeostasis and stomatal immunity. Communications Biology 2:1.
Crossref
Crossref
Victoriia Murina, Marje Kasari, Hiraku Takada, Mariliis Hinnu, Chayan Kumar Saha, James W. Grimshaw, Takahiro Seki, Michael Reith, Marta Putrinš, Tanel Tenson, Henrik Strahl, Vasili Hauryliuk & Gemma Catherine Atkinson. (2019) ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life. Journal of Molecular Biology 431:18, pages 3568-3590.
Crossref
Crossref
Alison J. Inglis, Glenn R. Masson, Sichen Shao, Olga Perisic, Stephen H. McLaughlin, Ramanujan S. Hegde & Roger L. Williams. (2019) Activation of GCN2 by the ribosomal P-stalk. Proceedings of the National Academy of Sciences 116:11, pages 4946-4954.
Crossref
Crossref
Corinna Niersmann, Stefanie M. Hauck, Julia M. Kannenberg, Karin Röhrig, Christine von Toerne, Michael Roden, Christian Herder & Maren Carstensen-Kirberg. (2019) Omentin-regulated proteins combine a pro-inflammatory phenotype with an anti-inflammatory counterregulation in human adipocytes: A proteomics analysis. Diabetes/Metabolism Research and Reviews 35:1, pages e3074.
Crossref
Crossref
Szymon Juszkiewicz, Viswanathan Chandrasekaran, Zhewang Lin, Sebastian Kraatz, V. Ramakrishnan & Ramanujan S. Hegde. (2018) ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Molecular Cell 72:3, pages 469-481.e7.
Crossref
Crossref
Mohd. Wasi, Nitesh Kumar Khandelwal, Poonam Vishwakarma, Andrew M. Lynn, Alok K. Mondal & Rajendra Prasad. (2018) Inventory of ABC proteins and their putative role in salt and drug tolerance in Debaryomyces hansenii. Gene 676, pages 227-242.
Crossref
Crossref
Michael J. Boucher, Sreejoyee Ghosh, Lichao Zhang, Avantika Lal, Se Won Jang, An Ju, Shuying Zhang, Xinzi Wang, Stuart A. Ralph, James Zou, Joshua E. Elias & Ellen Yeh. (2018) Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. PLOS Biology 16:9, pages e2005895.
Crossref
Crossref
Peter Amoako Ofori, Ayaka Mizuno, Mami Suzuki, Enrico Martinoia, Stefan Reuscher, Koh Aoki, Daisuke Shibata, Shungo Otagaki, Shogo Matsumoto & Katsuhiro Shiratake. (2018) Genome-wide analysis of ATP binding cassette (ABC) transporters in tomato. PLOS ONE 13:7, pages e0200854.
Crossref
Crossref
Ronald C. Wek. (2018) Role of eIF2α Kinases in Translational Control and Adaptation to Cellular Stress. Cold Spring Harbor Perspectives in Biology 10:7, pages a032870.
Crossref
Crossref
I. Faus, R. Niñoles, V. Kesari, P. Llabata, E. Tam, S.G. Nebauer, J. Santiago, M.T. Hauser & J. Gadea. (2018) Arabidopsis ILITHYIA protein is necessary for proper chloroplast biogenesis and root development independent of eIF2α phosphorylation. Journal of Plant Physiology 224-225, pages 173-182.
Crossref
Crossref
Lu Han, Michael P. Guy, Yoshiko Kon & Eric M. Phizicky. (2018) Lack of 2'-O-methylation in the tRNA anticodon loop of two phylogenetically distant yeast species activates the general amino acid control pathway. PLOS Genetics 14:3, pages e1007288.
Crossref
Crossref
Liam K. R. Sharkey & Alex J. O’Neill. (2018) Antibiotic Resistance ABC-F Proteins: Bringing Target Protection into the Limelight. ACS Infectious Diseases 4:3, pages 239-246.
Crossref
Crossref
Adriano C. Coelho & Paulo C. Cotrim. 2018. Drug Resistance in Leishmania Parasites. Drug Resistance in Leishmania Parasites
247
272
.
Lixia Tian, Tianxue Song, Rongjun He, Yang Zeng, Wen Xie, Qingjun Wu, Shaoli Wang, Xuguo Zhou & Youjun Zhang. (2017) Genome-wide analysis of ATP-binding cassette (ABC) transporters in the sweetpotato whitefly, Bemisia tabaci. BMC Genomics 18:1.
Crossref
Crossref
Ryan A. Coots, Xiao-Min Liu, Yuanhui Mao, Leiming Dong, Jun Zhou, Ji Wan, Xingqian Zhang & Shu-Bing Qian. (2017) m6A Facilitates eIF4F-Independent mRNA Translation. Molecular Cell 68:3, pages 504-514.e7.
Crossref
Crossref
Su Jung Lee, Rashmi Ramesh, Valerie de Boor, Jan M. Gebler, Richard C. Silva & Evelyn Sattlegger. (2017)
Cost-effective and rapid lysis of
Saccharomyces cerevisiae
cells for quantitative western blot analysis of proteins, including phosphorylated eIF2
α
. Yeast 34:9, pages 371-382.
Crossref
Crossref
Silje Anda, Róbert Zach & Beáta Grallert. (2017) Activation of Gcn2 in response to different stresses. PLOS ONE 12:8, pages e0182143.
Crossref
Crossref
Sara M. Wilcox, Hitesh Arora, Lonna Munro, Jian Xin, Franz Fenninger, Laura A. Johnson, Cheryl G. Pfeifer, Kyung Bok Choi, Juan Hou, Pamela A. Hoodless & Wilfred A. Jefferies. (2017) The role of the innate immune response regulatory gene ABCF1 in mammalian embryogenesis and development. PLOS ONE 12:5, pages e0175918.
Crossref
Crossref
Sezai Türkel & Süeda Sarica. (2017) Effects of stress activated protein kinases on the expression of EST3 gene that encodes telomerase subunit in Saccharomyces cerevisiae. Biologia 72:3, pages 252-258.
Crossref
Crossref
Wenjie Yuan, Shuguang Guo, Jiaoqi Gao, Mingming Zhong, Gonghong Yan, Wangmeng Wu, Yapeng Chao & Yu Jiang. (2017) General Control Nonderepressible 2 (GCN2) Kinase Inhibits Target of Rapamycin Complex 1 in Response to Amino Acid Starvation in Saccharomyces cerevisiae. Journal of Biological Chemistry 292:7, pages 2660-2669.
Crossref
Crossref
Daoyang Sun, Xinguo Zhang, Shaohua Li, Cai-Zhong Jiang, Yanlong Zhang & Lixin Niu. (2016) LrABCF1, a GCN-type ATP-binding cassette transporter from Lilium regale, is involved in defense responses against viral and fungal pathogens. Planta 244:6, pages 1185-1199.
Crossref
Crossref
Joseph A. Curran & Benjamin Weiss. (2016) What Is the Impact of mRNA 5′ TL Heterogeneity on Translational Start Site Selection and the Mammalian Cellular Phenotype?. Frontiers in Genetics 7.
Crossref
Crossref
Sezai Türkel. (2016)
Amino Acid Starvation Enhances Programmed Ribosomal Frameshift in Metavirus Ty3 of
Saccharomyces cerevisiae
. Advances in Biology 2016, pages 1-6.
Crossref
Crossref
Thomas E Dever, Terri Goss Kinzy & Graham D Pavitt. (2016)
Mechanism and Regulation of Protein Synthesis in
Saccharomyces cerevisiae
. Genetics 203:1, pages 65-107.
Crossref
Crossref
Ryuta Ishimura, Gabor Nagy, Ivan Dotu, Jeffrey H Chuang & Susan L Ackerman. (2016) Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation. eLife 5.
Crossref
Crossref
Sichen Shao & Ramanujan S. Hegde. (2016) Target Selection during Protein Quality Control. Trends in Biochemical Sciences 41:2, pages 124-137.
Crossref
Crossref
Richard C. Silva, Evelyn Sattlegger & Beatriz A. Castilho. (2016) Perturbations in actin dynamics reconfigure protein complexes that modulate GCN2 activity and promote an eIF2 response. Journal of Cell Science.
Crossref
Crossref
Stefan Rothenburg, Millie M. Georgiadis & Ronald C. Wek. 2016. Evolution of the Protein Synthesis Machinery and Its Regulation. Evolution of the Protein Synthesis Machinery and Its Regulation
235
260
.
Jie Xiong, Jinmei Feng, Dongxia Yuan, Jun Zhou & Wei Miao. (2015) Tracing the structural evolution of eukaryotic ATP binding cassette transporter superfamily. Scientific Reports 5:1.
Crossref
Crossref
Joanna D. StewartJoanne L. CowanLisa S. PerryMark J. ColdwellChristopher G. Proud. (2015) ABC50 mutants modify translation start codon selection. Biochemical Journal 467:2, pages 217-229.
Crossref
Crossref
Su Jung Lee, Mark J. SwansonEvelyn Sattlegger. (2015) Gcn1 contacts the small ribosomal protein Rps10, which is required for full activation of the protein kinase Gcn2. Biochemical Journal 466:3, pages 547-559.
Crossref
Crossref
Sebastien Lageix, Jinwei Zhang, Stefan Rothenburg & Alan G. Hinnebusch. (2015) Interaction between the tRNA-Binding and C-Terminal Domains of Yeast Gcn2 Regulates Kinase Activity In Vivo. PLOS Genetics 11:2, pages e1004991.
Crossref
Crossref
Beatriz A. Castilho, Renuka Shanmugam, Richard C. Silva, Rashmi Ramesh, Benjamin M. Himme & Evelyn Sattlegger. (2014) Keeping the eIF2 alpha kinase Gcn2 in check. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1843:9, pages 1948-1968.
Crossref
Crossref
Takashi Hirose & H. Robert Horvitz. (2014) The Translational Regulators GCN-1 and ABCF-3 Act Together to Promote Apoptosis in C. elegans. PLoS Genetics 10:8, pages e1004512.
Crossref
Crossref
Medha Raina & Michael Ibba. (2014) tRNAs as regulators of biological processes. Frontiers in Genetics 5.
Crossref
Crossref
Sebastien Lageix, Stefan Rothenburg, Thomas E. Dever & Alan G. Hinnebusch. (2014) Enhanced Interaction between Pseudokinase and Kinase Domains in Gcn2 stimulates eIF2α Phosphorylation in Starved Cells. PLoS Genetics 10:5, pages e1004326.
Crossref
Crossref
Andrew G. Cridge, Jyothsna Visweswaraiah, Rashmi Ramesh & Evelyn Sattlegger. (2014) Semi-quantitative colony immunoassay for determining and optimizing protein expression in Saccharomyces cerevisiae and Escherichia coli. Analytical Biochemistry 447, pages 82-89.
Crossref
Crossref
Tavane D. Cambiaghi, Catia M. Pereira, Renuka Shanmugam, Michael Bolech, Ronald C. Wek, Evelyn Sattlegger & Beatriz A. Castilho. (2014) Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2. Biochemical and Biophysical Research Communications 443:2, pages 592-597.
Crossref
Crossref
Rebecca L. Roston, Anna K. Hurlock & Christoph Benning. 2014. Plant ABC Transporters. Plant ABC Transporters
103
136
.
YanXia Xu & YanHua Qi. 2014. Plant ABC Transporters. Plant ABC Transporters
203
217
.
Kaiyuan Pang, Yanjiao Li, Menghan Liu, Zhaodong Meng & Yanli Yu. (2013) Inventory and general analysis of the ATP-binding cassette (ABC) gene superfamily in maize (Zea mays L.). Gene 526:2, pages 411-428.
Crossref
Crossref
Kosuke Ishikawa, Koichi Ito, Jun-ichiro Inoue & Kentaro Semba. (2013) Cell growth control by stable Rbg2/Gir2 complex formation under amino acid starvation. Genes to Cells, pages n/a-n/a.
Crossref
Crossref
Martín Roffé, Glaucia N.M. Hajj, Hátylas F. Azevedo, Viviane S. Alves & Beatriz A. Castilho. (2013) IMPACT Is a Developmentally Regulated Protein in Neurons That Opposes the Eukaryotic Initiation Factor 2α Kinase GCN2 in the modulation of Neurite Outgrowth. Journal of Biological Chemistry 288:15, pages 10860-10869.
Crossref
Crossref
Adriano C. Coelho & Paulo C. Cotrim. 2013. Drug Resistance in Leishmania Parasites. Drug Resistance in Leishmania Parasites
237
258
.
Jyothsna Visweswaraiah, Su Jung Lee, Alan G. Hinnebusch & Evelyn Sattlegger. (2012) Overexpression of Eukaryotic Translation Elongation Factor 3 Impairs Gcn2 Protein Activation. Journal of Biological Chemistry 287:45, pages 37757-37768.
Crossref
Crossref
Thomas D. Baird & Ronald C. Wek. (2012) Eukaryotic Initiation Factor 2 Phosphorylation and Translational Control in Metabolism. Advances in Nutrition 3:3, pages 307-321.
Crossref
Crossref
Tracey Waller, Su Jung Lee & Evelyn Sattlegger. (2012) Evidence that Yih1 resides in a complex with ribosomes. FEBS Journal 279:10, pages 1761-1776.
Crossref
Crossref
Julien Lupo, Audrey Conti, Charlotte Sueur, Pierre-Alain Coly, Yohann Couté, Walter Hunziker, Wim P. Burmeister, Raphaelle Germi, Evelyne Manet, Henri Gruffat, Patrice Morand & Véronique Boyer. (2012) Identification of new interacting partners of the shuttling protein ubinuclein (Ubn-1). Experimental Cell Research 318:5, pages 509-520.
Crossref
Crossref
Shumin Liu, Shun Zhou, Ling Tian, Enen Guo, Yunxia Luan, Jianzhen Zhang & Sheng Li. (2011) Genome-wide identification and characterization of ATP-binding cassette transporters in the silkworm, Bombyx mori. BMC Genomics 12:1.
Crossref
Crossref
James M. Dorrian, Deborah A. Briggs, Michael L. Ridley, Robert Layfield & Ian D. Kerr. (2011) Induction of a stress response in Lactococcus lactis is associated with a resistance to ribosomally active antibiotics. FEBS Journal 278:21, pages 4015-4024.
Crossref
Crossref
Weiqing Zeng, Alexandre Brutus, James M. Kremer, John C. Withers, Xiaoli Gao, A. Daniel Jones & Sheng Yang He. (2011) A Genetic Screen Reveals Arabidopsis Stomatal and/or Apoplastic Defenses against Pseudomonas syringae pv. tomato DC3000. PLoS Pathogens 7:10, pages e1002291.
Crossref
Crossref
Jyothsna Visweswaraiah, Sebastien Lageix, Beatriz A. Castilho, Lara Izotova, Terri Goss Kinzy, Alan G. Hinnebusch & Evelyn Sattlegger. (2011) Evidence That Eukaryotic Translation Elongation Factor 1A (eEF1A) Binds the Gcn2 Protein C Terminus and Inhibits Gcn2 Activity*. Journal of Biological Chemistry 286:42, pages 36568-36579.
Crossref
Crossref
Cornelia Klein, Karl Kuchler & Martin Valachovic. (2011) ABC proteins in yeast and fungal pathogens. Essays in Biochemistry 50, pages 101-119.
Crossref
Crossref
Jay E. Mittenthal & Lihua Zou. (2011) To signal a conjunction of many inputs negative regulation is likely. Mathematical Biosciences 231:1, pages 69-75.
Crossref
Crossref
Marie-Claire Daugeron, Manoël Prouteau, François Lacroute & Bertrand Séraphin. (2011) The highly conserved eukaryotic DRG factors are required for efficient translation in a manner redundant with the putative RNA helicase Slh1. Nucleic Acids Research 39:6, pages 2221-2233.
Crossref
Crossref
Evelyn Sattlegger, João A.R.G. Barbosa, Maria Carolina S. Moraes, Rafael M. Martins, Alan G. Hinnebusch & Beatriz A. Castilho. (2011) Gcn1 and Actin Binding to Yih1. Journal of Biological Chemistry 286:12, pages 10341-10355.
Crossref
Crossref
Jie Xiong, Lifang Feng, Dongxia Yuan, Chengjie Fu & Wei Miao. (2010) Genome-wide identification and evolution of ATP-binding cassette transporters in the ciliate Tetrahymena thermophila: A case of functional divergence in a multigene family. BMC Evolutionary Biology 10:1.
Crossref
Crossref
Jacqueline Monaghan & Xin Li. (2010) The HEAT Repeat Protein ILITYHIA is Required for Plant Immunity. Plant and Cell Physiology 51:5, pages 742-753.
Crossref
Crossref
Monica Y. Burgos Zepeda, Kevin Alessandri, Dorothée Murat, Chahrazade El Amri & Elie Dassa. (2010) C-terminal domain of the Uup ATP-binding cassette ATPase is an essential folding domain that binds to DNA. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1804:4, pages 755-761.
Crossref
Crossref
Andrey V. Pisarev, Maxim A. Skabkin, Vera P. Pisareva, Olga V. Skabkina, Aurélie M. Rakotondrafara, Matthias W. Hentze, Christopher U.T. Hellen & Tatyana V. Pestova. (2010) The Role of ABCE1 in Eukaryotic Posttermination Ribosomal Recycling. Molecular Cell 37:2, pages 196-210.
Crossref
Crossref
Armin Sturm, Phil Cunningham & Michael Dean. (2009) The ABC transporter gene family of Daphnia pulex. BMC Genomics 10:1.
Crossref
Crossref
Sonia Paytubi, Xuemin Wang, Yun W. Lam, Luis Izquierdo, Mairi J. Hunter, Eric Jan, Harinder S. Hundal & Christopher G. Proud. (2009) ABC50 Promotes Translation Initiation in Mammalian Cells. Journal of Biological Chemistry 284:36, pages 24061-24073.
Crossref
Crossref
P. K. Wout, E. Sattlegger, S. M. Sullivan & J. R. Maddock. (2009)
Saccharomyces cerevisiae
Rbg1 Protein and Its Binding Partner Gir2 Interact on Polyribosomes with Gcn1
. Eukaryotic Cell 8:7, pages 1061-1071.
Crossref
Crossref
Shadia ZamanSoyeon Im LippmanXin ZhaoJames R. Broach. (2008)
How
Saccharomyces
Responds to Nutrients
. Annual Review of Genetics 42:1, pages 27-81.
Crossref
Crossref
Robert E. Drew, Kenneth J. Rodnick, Matthew Settles, Jurij Wacyk, Erin Churchill, Madison S. Powell, Ronald W. Hardy, Gordon K. Murdoch, Rodney A. Hill & Barrie D. Robison. (2008)
Effect of starvation on transcriptomes of brain and liver in adult female zebrafish (
Danio rerio
)
. Physiological Genomics 35:3, pages 283-295.
Crossref
Crossref
Sonia PaytubiNicholas A. MorriceJerome BoudeauChristopher G. Proud. (2007) The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2. Biochemical Journal 409:1, pages 223-231.
Crossref
Crossref
Zbynek Bozdech & Erwin Schurr. 2007. Novartis Foundation Symposium 226 - Transport and Trafficking in the Malaria-Infected Erythrocyte. Novartis Foundation Symposium 226 - Transport and Trafficking in the Malaria-Infected Erythrocyte
231
251
.
Ethan O Perlstein, Douglas M Ruderfer, David C Roberts, Stuart L Schreiber & Leonid Kruglyak. (2007) Genetic basis of individual differences in the response to small-molecule drugs in yeast. Nature Genetics 39:4, pages 496-502.
Crossref
Crossref
Helen S. Atkins, Elie Dassa, Nicola J. Walker, Kate F. Griffin, David N. Harland, Rosa R. Taylor, Melanie L. Duffield & Richard W. Titball. (2006) The identification and evaluation of ATP binding cassette systems in the intracellular bacterium Francisella tularensis. Research in Microbiology 157:6, pages 593-604.
Crossref
Crossref
Elena Marin, Fanchon Divol, Nicole Bechtold, Alain Vavasseur, Laurent Nussaume & Cyrille Forestier. (2006) Molecular characterization of three Arabidopsis soluble ABC proteins which expression is induced by sugars. Plant Science 171:1, pages 84-90.
Crossref
Crossref
K. E. MOUNSEY, D. C. HOLT, J. McCARTHY & S. F. WALTON. (2006)
Identification of ABC transporters in
Sarcoptes scabiei
. Parasitology 132:6, pages 883-892.
Crossref
Crossref
Virginie Sauvage, Jean-Marc Millot, Dominique Aubert, Vincent Visneux, Maggy Marle-Plistat, Jean-Michel Pinon & Isabelle Villena. (2006) Identification and expression analysis of ABC protein-encoding genes in Toxoplasma gondii. Molecular and Biochemical Parasitology 147:2, pages 177-192.
Crossref
Crossref
Dorothée Murat, Pierre Bance, Isabelle Callebaut & Elie Dassa. (2006) ATP Hydrolysis Is Essential for the Function of the Uup ATP-binding Cassette ATPase in Precise Excision of Transposons. Journal of Biological Chemistry 281:10, pages 6850-6859.
Crossref
Crossref
David Li-En Jao & Kuang Yu Chen. (2006) Tandem affinity purification revealed the hypusine-dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex. Journal of Cellular Biochemistry 97:3, pages 583-598.
Crossref
Crossref
Lotte Steffensen & Per Amstrup Pedersen. (2006)
Heterologous Expression of Membrane and Soluble Proteins Derepresses
GCN4
mRNA Translation in the Yeast
Saccharomyces cerevisiae
. Eukaryotic Cell 5:2, pages 248-261.
Crossref
Crossref
Alan G. Hinnebusch. (2005)
TRANSLATIONAL REGULATION OF
GCN4
AND THE GENERAL AMINO ACID CONTROL OF YEAST
. Annual Review of Microbiology 59:1, pages 407-450.
Crossref
Crossref
Qinghu Ren & Ian T. Paulsen. 2005. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics.
Michael DeanTarmo Annilo. (2005) EVOLUTION OF THE ATP-BINDING CASSETTE (ABC) TRANSPORTER SUPERFAMILY IN VERTEBRATES. Annual Review of Genomics and Human Genetics 6:1, pages 123-142.
Crossref
Crossref
Anil K. Padyana, Hongfang Qiu, Antonina Roll-Mecak, Alan G. Hinnebusch & Stephen K. Burley. (2005) Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2α Protein Kinase GCN2*[boxs]. Journal of Biological Chemistry 280:32, pages 29289-29299.
Crossref
Crossref
Cátia M. Pereira, Evelyn Sattlegger, Hao-Yuan Jiang, Beatriz M. Longo, Carolina B. Jaqueta, Alan G. Hinnebusch, Ronald C. Wek, Luiz E.A.M. Mello & Beatriz A. Castilho. (2005) IMPACT, a Protein Preferentially Expressed in the Mouse Brain, Binds GCN1 and Inhibits GCN2 Activation. Journal of Biological Chemistry 280:31, pages 28316-28323.
Crossref
Crossref
Evelyn Sattlegger & Alan G. Hinnebusch. (2005) Polyribosome Binding by GCN1 Is Required for Full Activation of Eukaryotic Translation Initiation Factor 2α Kinase GCN2 during Amino Acid Starvation. Journal of Biological Chemistry 280:16, pages 16514-16521.
Crossref
Crossref
Christopher G. Proud. (2005) eIF2 and the control of cell physiology. Seminars in Cell & Developmental Biology 16:1, pages 3-12.
Crossref
Crossref
Ke Zhan, Jana Narasimhan & Ronald C Wek. (2004) Differential Activation of eIF2 Kinases in Response to Cellular Stresses in Schizosaccharomyces pombe. Genetics 168:4, pages 1867-1875.
Crossref
Crossref
Jinsheng Dong, Ruby Lai, Klaus Nielsen, Christie A. Fekete, Hongfang Qiu & Alan G. Hinnebusch. (2004) The Essential ATP-binding Cassette Protein RLI1 Functions in Translation by Promoting Preinitiation Complex Assembly. Journal of Biological Chemistry 279:40, pages 42157-42168.
Crossref
Crossref
Olivier Garcia, Philippe Bouige, Cyrille Forestier & Elie Dassa. (2004) Inventory and Comparative Analysis of Rice and Arabidopsis ATP-binding Cassette (ABC) Systems. Journal of Molecular Biology 343:1, pages 249-265.
Crossref
Crossref
Evelyn Sattlegger, Mark J. Swanson, Emily A. Ashcraft, Jennifer L. Jennings, Richard A. Fekete, Andrew J. Link & Alan G. Hinnebusch. (2004) YIH1 Is an Actin-binding Protein That Inhibits Protein Kinase GCN2 and Impairs General Amino Acid Control When Overexpressed. Journal of Biological Chemistry 279:29, pages 29952-29962.
Crossref
Crossref
Jana Narasimhan, Kirk A. Staschke & Ronald C. Wek. (2004) Dimerization Is Required for Activation of eIF2 Kinase Gcn2 in Response to Diverse Environmental Stress Conditions. Journal of Biological Chemistry 279:22, pages 22820-22832.
Crossref
Crossref
J Richard Dickinson. 2004. Metabolism and Molecular Physiology of Saccharomyces Cerevisiae, 2nd Edition. Metabolism and Molecular Physiology of Saccharomyces Cerevisiae, 2nd Edition
104
116
.
Y. Zhao, H. Wang, R. W. Hammond, R. Jomantiene, Q. Liu, S. Lin, B. A. Roe & R. E. Davis. (2004) Predicted ATP-binding cassette systems in the phytopathogenic mollicute Spiroplasma kunkelii. Molecular Genetics and Genomics 271:3, pages 325-338.
Crossref
Crossref
Ian D Kerr. (2004) Sequence analysis of twin ATP binding cassette proteins involved in translational control, antibiotic resistance, and ribonuclease L inhibition. Biochemical and Biophysical Research Communications 315:1, pages 166-173.
Crossref
Crossref
Boris Shor, Jimmy Calaycay, Julie Rushbrook & Maureen McLeod. (2003) Cpc2/RACK1 Is a Ribosome-associated Protein That Promotes Efficient Translation in Schizosaccharomyces pombe. Journal of Biological Chemistry 278:49, pages 49119-49128.
Crossref
Crossref
CHRISTOPH SCHÜLLER, BETTINA E. BAUER & KARL KUCHLER. 2003. ABC Proteins. ABC Proteins
279
293
.
MICHAEL DEAN, ANDREY RZHETSKY & RANDO ALLIKMETS. 2003. ABC Proteins. ABC Proteins
47
61
.
ELIE DASSA. 2003. ABC Proteins. ABC Proteins
3
35
.
Christophe Anjard & William F. Loomis. (2002)
Evolutionary Analyses of ABC Transporters of
Dictyostelium discoideum
. Eukaryotic Cell 1:4, pages 643-652.
Crossref
Crossref
Minerva Garcia-Barrio, Jinsheng Dong, Vera A. Cherkasova, Xiaolong Zhang, Fan Zhang, Sandra Ufano, Ruby Lai, Jun Qin & Alan G. Hinnebusch. (2002) Serine 577 Is Phosphorylated and Negatively Affects the tRNA Binding and eIF2α Kinase Activities of GCN2. Journal of Biological Chemistry 277:34, pages 30675-30683.
Crossref
Crossref
Bing Tian, Yuhong Zhang, Bruce A. Luxon, Roberto P. Garofalo, Antonella Casola, Mala Sinha & Allan R. Brasier. (2002) Identification of NF-κB-Dependent Gene Networks in Respiratory Syncytial Virus-Infected Cells. Journal of Virology 76:13, pages 6800-6814.
Crossref
Crossref
Hongfang Qiu, Cuihua Hu, Jinsheng Dong & Alan G. Hinnebusch. (2002) Mutations that bypass tRNA binding activate the intrinsically defective kinase domain in GCN2. Genes & Development 16:10, pages 1271-1280.
Crossref
Crossref
Emmanuel Cornillot, Guy Metenier, Christian P. Vivares & Elie Dassa. (2002)
Comparative analysis of sequences encoding ABC systems in the genome of the microsporidian
Encephalitozoon cuniculi
. FEMS Microbiology Letters 210:1, pages 39-47.
Crossref
Crossref
Alan G. Hinnebusch & Krishnamurthy Natarajan. (2002) Gcn4p, a Master Regulator of Gene Expression, Is Controlled at Multiple Levels by Diverse Signals of Starvation and Stress. Eukaryotic Cell 1:1, pages 22-32.
Crossref
Crossref
Michael Dean, Andrey Rzhetsky & Rando Allikmets. (2001) The Human ATP-Binding Cassette (ABC) Transporter Superfamily. Genome Research 11:7, pages 1156-1166.
Crossref
Crossref
Michael Dean, Yannick Hamon & Giovanna Chimini. (2001) The human ATP-binding cassette (ABC) transporter superfamily. Journal of Lipid Research 42:7, pages 1007-1017.
Crossref
Crossref
Hiroyuki Kubota, Kazuhisa Ota, Yoshiyuki Sakaki & Takashi Ito. (2001) Budding Yeast GCN1 Binds the GI Domain to Activate the eIF2α Kinase GCN2. Journal of Biological Chemistry 276:20, pages 17591-17596.
Crossref
Crossref
Kalpana Chakraburtty. (2001) Translational regulation by ABC systems. Research in Microbiology 152:3-4, pages 391-399.
Crossref
Crossref
Hubert Wolfger, Yasmine M Mamnun & Karl Kuchler. (2001) Fungal ABC proteins: pleiotropic drug resistance, stress response and cellular detoxification. Research in Microbiology 152:3-4, pages 375-389.
Crossref
Crossref
Elie Dassa & Philippe Bouige. (2001) The ABC of ABCs: a phylogenetic and functional classification of ABC systems in living organisms. Research in Microbiology 152:3-4, pages 211-229.
Crossref
Crossref
Amelia J. Entingh, Brian K. Law & Harold L. Moses. (2001) Induction of the C/EBP Homologous Protein (CHOP) by Amino Acid Deprivation Requires Insulin-Like Growth Factor I, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Signaling**This work was supported by NIH Grants CA-42572 and CA-85492. Sequencing was carried out by the DNA Sequencing Shared Resource (Grant P30-CA-68485). Data presentation was performed in part through the use of the Vanderbilt University Medical Center Cell Imaging Resource (Grants CA-68485 and DK-20593).. Endocrinology 142:1, pages 221-228.
Crossref
Crossref
Michael J. Clemens. 2001. Signaling Pathways for Translation. Signaling Pathways for Translation
57
89
.
Scot R. Kimball. 2001. Signaling Pathways for Translation. Signaling Pathways for Translation
155
184
.
Jonathan K. Tyzack, Xuemin Wang, Graham J. Belsham & Christopher G. Proud. (2000) ABC50 Interacts with Eukaryotic Initiation Factor 2 and Associates with the Ribosome in an ATP-dependent Manner. Journal of Biological Chemistry 275:44, pages 34131-34139.
Crossref
Crossref
Martine Braibant, Philippe Gilot & Jean Content. (2000)
The ATP binding cassette (ABC) transport systems of
Mycobacterium tuberculosis
. FEMS Microbiology Reviews 24:4, pages 449-467.
Crossref
Crossref
Andrew F. Neuwald & Tatsuya Hirano. (2000) HEAT Repeats Associated with Condensins, Cohesins, and Other Complexes Involved in Chromosome-Related Functions. Genome Research 10:10, pages 1445-1452.
Crossref
Crossref
Hiroyuki Kubota, Yoshiyuki Sakaki & Takashi Ito. (2000) GI Domain-mediated Association of the Eukaryotic Initiation Factor 2α Kinase GCN2 with Its Activator GCN1 Is Required for General Amino Acid Control in Budding Yeast. Journal of Biological Chemistry 275:27, pages 20243-20246.
Crossref
Crossref
Bernd Hoffmann, Christoph Wanke, S. Kirsten LaPaglia & Gerhard H. Braus. (2000) c-Jun and RACK1 homologues regulate a control point for sexual development in Aspergillus nidulans. Molecular Microbiology 37:1, pages 28-41.
Crossref
Crossref
Ruchira Sood, Amy C Porter, DeAnne Olsen, Douglas R Cavener & Ronald C Wek. (2000) A Mammalian Homologue of GCN2 Protein Kinase Important for Translational Control by Phosphorylation of Eukaryotic Initiation Factor-2α. Genetics 154:2, pages 787-801.
Crossref
Crossref
Bettina E Bauer, Hubert Wolfger & Karl Kuchler. (1999) Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance. Biochimica et Biophysica Acta (BBA) - Biomembranes 1461:2, pages 217-236.
Crossref
Crossref
Juan J. Berlanga, Javier Santoyo & Cesar de Haro. (1999) Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase. European Journal of Biochemistry 265:2, pages 754-762.
Crossref
Crossref
David A. Mangus & Allan Jacobson. (1999) Linking mRNA Turnover and Translation: Assessing the Polyribosomal Association of mRNA Decay Factors and Degradative Intermediates. Methods 17:1, pages 28-37.
Crossref
Crossref
John E. G. McCarthy. (1998) Posttranscriptional Control of Gene Expression in Yeast. Microbiology and Molecular Biology Reviews 62:4, pages 1492-1553.
Crossref
Crossref
Zbynek Bozdech, Jeffrey VanWye, Kasturi Haldar & Erwin Schurr. (1998) The human malaria parasite Plasmodium falciparum exports the ATP-binding cassette protein PFGCN20 to membrane structures in the host red blood cell. Molecular and Biochemical Parasitology 97:1-2, pages 81-95.
Crossref
Crossref
Sang Ki ChoiJoon H. LeeWendy L. ZollWilliam C. MerrickThomas E. Dever. (1998)
Promotion of Met-tRNA
i
Met
Binding to Ribosomes by yIF2, a Bacterial IF2 Homolog in Yeast
. Science 280:5370, pages 1757-1760.
Crossref
Crossref
Luther Davis & JoAnne Engebrecht. (1998) Yeast dom34 Mutants Are Defective in Multiple Developmental Pathways and Exhibit Decreased Levels of Polyribosomes. Genetics 149:1, pages 45-56.
Crossref
Crossref
Shuhao Zhu & Ronald C. Wek. (1998) Ribosome-binding Domain of Eukaryotic Initiation Factor-2 Kinase GCN2 Facilitates Translation Control. Journal of Biological Chemistry 273:3, pages 1808-1814.
Crossref
Crossref