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Research Article

E2A Deficiency Leads to Abnormalities in αβ T-Cell Development and to Rapid Development of T-Cell Lymphomas

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Pages 4782-4791 | Received 11 Mar 1997, Accepted 09 May 1997, Published online: 29 Mar 2023

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Aubrey Hunt, Melissa Fischer, Michael E. Engel & Scott W. Hiebert. (2011) Mtg16/Eto2 Contributes to Murine T-Cell Development. Molecular and Cellular Biology 31:13, pages 2544-2551.
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Marsela Braunstein & Michele K. Anderson. (2011) HEB-Deficient T-Cell Precursors Lose T-Cell Potential and Adopt an Alternative Pathway of Differentiation. Molecular and Cellular Biology 31:5, pages 971-982.
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Hong-Cheng Wang, S. Scott Perry & Xiao-Hong Sun. (2009) Id1 Attenuates Notch Signaling and Impairs T-Cell Commitment by Elevating Deltex1 Expression. Molecular and Cellular Biology 29:17, pages 4640-4652.
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Zhong Huang, Lei Nie, Min Xu & Xiao-Hong Sun. (2004) Notch-Induced E2A Degradation Requires CHIP and Hsc70 as Novel Facilitators of Ubiquitination. Molecular and Cellular Biology 24:20, pages 8951-8962.
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Thorsten M. Schlaeger, Anna Schuh, Simon Flitter, Andreas Fisher, Hanna Mikkola, Stuart H. Orkin, Paresh Vyas & Catherine Porcher. (2004) Decoding Hematopoietic Specificity in the Helix-Loop-Helix Domain of the Transcription Factor SCL/Tal-1. Molecular and Cellular Biology 24:17, pages 7491-7502.
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Zengbiao Qi & Xiao-Hong Sun. (2004) Hyperresponse to T-Cell Receptor Signaling and Apoptosis of Id1 Transgenic Thymocytes. Molecular and Cellular Biology 24:17, pages 7313-7323.
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Matthew P. McCormack, Alan Forster, Lesley Drynan, Richard Pannell & Terence H. Rabbitts. (2003) The LMO2 T-Cell Oncogene Is Activated via Chromosomal Translocations or Retroviral Insertion during Gene Therapy but Has No Mandatory Role in Normal T-Cell Development. Molecular and Cellular Biology 23:24, pages 9003-9013.
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Sabine Herblot, Peter D. Aplan & Trang Hoang. (2002) Gradient of E2A Activity in B-Cell Development. Molecular and Cellular Biology 22:3, pages 886-900.
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Fang Zhao, Antonina Vilardi, Robert J. Neely & John Kim Choi. (2001) Promotion of Cell Cycle Progression by Basic Helix-Loop-Helix E2A. Molecular and Cellular Biology 21:18, pages 6346-6357.
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Robert J. Barndt, Meifang Dai & Yuan Zhuang. (2000) Functions of E2A-HEB Heterodimers in T-Cell Development Revealed by a Dominant Negative Mutation of HEB. Molecular and Cellular Biology 20:18, pages 6677-6685.
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Richard Bayly & David P. LeBrun. (2000) Role for Homodimerization in Growth Deregulation by E2a Fusion Proteins. Molecular and Cellular Biology 20:16, pages 5789-5796.
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Suming Huang & Stephen J. Brandt. (2000) mSin3A Regulates Murine Erythroleukemia Cell Differentiation through Association with the TAL1 (or SCL) Transcription Factor. Molecular and Cellular Biology 20:6, pages 2248-2259.
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Mark Eben Massari & Cornelis Murre. (2000) Helix-Loop-Helix Proteins: Regulators of Transcription in Eucaryotic Organisms. Molecular and Cellular Biology 20:2, pages 429-440.
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Dongsoo Kim, Xiao-Cong Peng & Xiao-Hong Sun. (1999) Massive Apoptosis of Thymocytes in T-Cell-Deficient Id1 Transgenic Mice. Molecular and Cellular Biology 19:12, pages 8240-8253.
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David S. Chervinsky, Xian-Feng Zhao, Du H. Lam, MaryKay Ellsworth, Kenneth W. Gross & Peter D. Aplan. (1999) Disordered T-Cell Development and T-Cell Malignancies in SCL LMO1 Double-Transgenic Mice: Parallels with E2A-Deficient Mice. Molecular and Cellular Biology 19:7, pages 5025-5035.
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Kevin S. Smith, Joon Whan Rhee, Louie Naumovski & Michael L. Cleary. (1999) Disrupted Differentiation and Oncogenic Transformation of Lymphoid Progenitors in E2A-HLF Transgenic Mice. Molecular and Cellular Biology 19:6, pages 4443-4451.
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Mark Eben Massari, Richard R. Rivera, Joseph R. Voland, Melanie W Quong, Timo M. Breit, Jacques J. M. van Dongen, Oncko de Smit & Cornelis Murre. (1998) Characterization of ABF-1, a Novel Basic Helix-Loop-Helix Transcription Factor Expressed in Activated B Lymphocytes. Molecular and Cellular Biology 18:6, pages 3130-3139.
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