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Transcriptional Regulation

p130 Is Dispensable in Peripheral T Lymphocytes: Evidence for Functional Compensation by p107 and pRB

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Pages 206-220 | Received 23 Jun 1997, Accepted 06 Oct 1997, Published online: 28 Mar 2023

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Chantal Forristal, Shauna A. Henley, James I. MacDonald, Jason R. Bush, Carley Ort, Daniel T. Passos, Srikanth Talluri, Charles A. Ishak, Michael J. Thwaites, Chris J. Norley, Larisa Litovchick, James A. DeCaprio, Gabriel DiMattia, David W. Holdsworth, Frank Beier & Frederick A. Dick. (2014) Loss of the Mammalian DREAM Complex Deregulates Chondrocyte Proliferation. Molecular and Cellular Biology 34:12, pages 2221-2234.
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Srikanth Talluri, Christian E. Isaac, Mohammad Ahmad, Shauna A. Henley, Sarah M. Francis, Alison L. Martens, Rod Bremner & Frederick A. Dick. (2010) A G1 Checkpoint Mediated by the Retinoblastoma Protein That Is Dispensable in Terminal Differentiation but Essential for Senescence. Molecular and Cellular Biology 30:4, pages 948-960.
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Jonathan P. Williams, Timothy Stewart, Bihua Li, Roseann Mulloy, Dessislava Dimova & Marie Classon. (2006) The Retinoblastoma Protein Is Required for Ras-Induced Oncogenic Transformation. Molecular and Cellular Biology 26:4, pages 1170-1182.
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Kaoru Tominaga, D. Mitchell Magee, Martin M. Matzuk & Olivia M. Pereira-Smith. (2004) PAM14, a Novel MRG- and Rb-Associated Protein, Is Not Required for Development and T-Cell Function in Mice. Molecular and Cellular Biology 24:19, pages 8366-8373.
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Jing W. Zhu, Seth J. Field, Lia Gore, Margaret Thompson, Haidi Yang, Yuko Fujiwara, Robert D. Cardiff, Michael Greenberg, Stuart H. Orkin & James DeGregori. (2001) E2F1 and E2F2 Determine Thresholds for Antigen-Induced T-Cell Proliferation and Suppress Tumorigenesis. Molecular and Cellular Biology 21:24, pages 8547-8564.
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Sonia Ciarmatori, Pamela H. Scott, Josephine E. Sutcliffe, Angela McLees, Hadi M. Alzuherri, Jan-Hermen Dannenberg, Hein te Riele, Ingrid Grummt, Renate Voit & Robert J. White. (2001) Overlapping Functions of the pRb Family in the Regulation of rRNA Synthesis. Molecular and Cellular Biology 21:17, pages 5806-5814.
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Caterina Cinti & Antonio Giordano. (2000) The retinoblastoma gene family: its role in cancer onset and progression. Emerging Therapeutic Targets 4:6, pages 765-783.
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Heather H. Shih, Sergei G. Tevosian & Amy S. Yee. (1998) Regulation of Differentiation by HBP1, a Target of the Retinoblastoma Protein. Molecular and Cellular Biology 18:8, pages 4732-4743.
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Amy S. Yee, Heather H. Shih & Sergei G. Tevosian. (1998) New Perspectives on Retinoblastoma Family Functions in Differentiation. Pediatric Pathology & Molecular Medicine 18:3, pages 275-302.
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Rosalyn W. Sayaman, Mohamad Saad, Vésteinn Thorsson, Donglei Hu, Wouter Hendrickx, Jessica Roelands, Eduard Porta-Pardo, Younes Mokrab, Farshad Farshidfar, Tomas Kirchhoff, Randy F. Sweis, Oliver F. Bathe, Carolina Heimann, Michael J. Campbell, Cynthia Stretch, Scott Huntsman, Rebecca E. Graff, Najeeb Syed, Laszlo Radvanyi, Simon Shelley, Denise Wolf, Francesco M. Marincola, Michele Ceccarelli, Jérôme Galon, Elad Ziv & Davide Bedognetti. (2021) Germline genetic contribution to the immune landscape of cancer. Immunity 54:2, pages 367-386.e8.
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Mohamed A. El-Brolosy & Didier Y. R. Stainier. (2017) Genetic compensation: A phenomenon in search of mechanisms. PLOS Genetics 13:7, pages e1006780.
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Yurong Song, Teresa Sullivan, Kimberly Klarmann, Debra Gilbert, T. Norene O’Sullivan, Lucy Lu, Sophie Wang, Diana C. Haines, Terry Van Dyke & Jonathan R. Keller. (2017) RB inactivation in keratin 18 positive thymic epithelial cells promotes non-cell autonomous T cell hyperproliferation in genetically engineered mice. PLOS ONE 12:2, pages e0171510.
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Oliver Xiaoou Dong, Meixuezi Tong, Vera Bonardi, Farid El Kasmi, Virginia Woloshen, Lisa K. Wünsch, Jeffery L. Dangl & Xin Li. (2016) TNL ‐mediated immunity in A rabidopsis requires complex regulation of the redundant ADR 1 gene family . New Phytologist 210:3, pages 960-973.
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Guillaume Diss, Diana Ascencio, Alexander DeLuna & Christian R. Landry. (2014) Molecular mechanisms of paralogous compensation and the robustness of cellular networks. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 322:7, pages 488-499.
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George HarbRupangi C. VasavadaDavid CobrinikAndrew F. Stewart. (2009) The Retinoblastoma Protein and Its Homolog p130 Regulate the G1/S Transition in Pancreatic β-Cells. Diabetes 58:8, pages 1852-1862.
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V M Ho, B E Schaffer, A N Karnezis, K S Park & J Sage. (2009) The retinoblastoma gene Rb and its family member p130 suppress lung adenocarcinoma induced by oncogenic K-Ras. Oncogene 28:10, pages 1393-1399.
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Anne-Marie Genevière, Antoine Aze, Yasmine Even, Maria Imschenetzky, Clara Nervi & Luigi Vitelli. 2009. Stem Cells in Marine Organisms. Stem Cells in Marine Organisms 215 244 .
Xiao Tang Hu. (2008) TGFβ-mediated formation of pRb–E2F complexes in human myeloid leukemia cells. Biochemical and Biophysical Research Communications 369:2, pages 277-280.
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Ling XueHector NollaAkira Suzuki, Tak W. Mak & Astar Winoto. (2008) Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice. Proceedings of the National Academy of Sciences 105:6, pages 2022-2027.
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Yang Wang, Subir K. Ray, Philip W. Hinds & Andrew B. Leiter. (2007) The retinoblastoma protein, RB, is required for gastrointestinal endocrine cells to exit the cell cycle, but not for hormone expression. Developmental Biology 311:2, pages 478-486.
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Claudia Andreu-Vieyra, Ruihong Chen & Martin M. Matzuk. (2007) Effects of Granulosa Cell-Specific Deletion of Rb in Inha-α Null Female Mice. Endocrinology 148:8, pages 3837-3849.
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Ruth A. Cosgrove & A. Philpott. (2007) Cell cycling and differentiation do not require the retinoblastoma protein during early Xenopus development. Developmental Biology 303:1, pages 311-324.
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Karl Münger, Peter Howley & Daniel DiMaio. 2007. The Papillomaviruses. The Papillomaviruses 197 252 .
M Macaluso, M Montanari & A Giordano. (2006) Rb family proteins as modulators of gene expression and new aspects regarding the interaction with chromatin remodeling enzymes. Oncogene 25:38, pages 5263-5267.
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Kevin Haigis, Julien Sage, Jon Glickman, Sarah Shafer & Tyler Jacks. (2006) The Related Retinoblastoma (pRb) and p130 Proteins Cooperate to Regulate Homeostasis in the Intestinal Epithelium. Journal of Biological Chemistry 281:1, pages 638-647.
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David Cobrinik. (2005) Pocket proteins and cell cycle control. Oncogene 24:17, pages 2796-2809.
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Desssislava K Dimova & Nicholas J Dyson. (2005) The E2F transcriptional network: old acquaintances with new faces. Oncogene 24:17, pages 2810-2826.
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Natividad de las Cuevas, Elena Urcelay, Ofelia G Hermida, Rosa A Saíz-Diaz, Félix Bermejo, Matilde S Ayuso & Angeles Martín-Requero. (2003) Ca2+/calmodulin-dependent modulation of cell cycle elements pRb and p27kip1 involved in the enhanced proliferation of lymphoblasts from patients with Alzheimer dementia. Neurobiology of Disease 13:3, pages 254-263.
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Rebecca L. Landsberg, Julia E. Sero, Paul S. Danielian, Tina L. Yuan, Eunice Y. Lee & Jacqueline A. Lees. (2003) The role of E2F4 in adipogenesis is independent of its cell cycle regulatory activity. Proceedings of the National Academy of Sciences 100:5, pages 2456-2461.
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Xue-Chu Zhao, Xiang Qu, Dennis E. Mathews & G. Eric Schaller. (2002) Effect of Ethylene Pathway Mutations upon Expression of the Ethylene Receptor ETR1 from Arabidopsis. Plant Physiology 130:4, pages 1983-1991.
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Marie Classon & Ed Harlow. (2002) The retinoblastoma tumour suppressor in development and cancer. Nature Reviews Cancer 2:12, pages 910-917.
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Tiziana Tonini, Christina Hillson & Pier Paolo Claudio. (2002) Interview with the retinoblastoma family members: Do they help each other?. Journal of Cellular Physiology 192:2, pages 138-150.
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Marie Classon & Nicholas Dyson. (2001) p107 and p130: Versatile Proteins with Interesting Pockets. Experimental Cell Research 264:1, pages 135-147.
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Jan-Hermen Dannenberg, Agnes van Rossum, Leontine Schuijff & Hein te Riele. (2000) Ablation of the Retinoblastoma gene family deregulates G 1 control causing immortalization and increased cell turnover under growth-restricting conditions . Genes & Development 14:23, pages 3051-3064.
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Julien Sage, George J. Mulligan, Laura D. Attardi, Abigail Miller, SiQi Chen, Bart Williams, Elias Theodorou & Tyler Jacks. (2000) Targeted disruption of the three Rb-related genes leads to loss of G 1 control and immortalization . Genes & Development 14:23, pages 3037-3050.
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Marie Classon, Sofie Salama, Carolyn Gorka, Roseann Mulloy, Pascal Braun & Ed Harlow. (2000) Combinatorial roles for pRB, p107, and p130 in E2F-mediated cell cycle control. Proceedings of the National Academy of Sciences 97:20, pages 10820-10825.
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Lengya Cheng, Ferdinando Rossi, Weizhao Fang, Takahiro Mori & David Cobrinik. (2000) Cdk2-dependent Phosphorylation and Functional Inactivation of the pRB-related p130 Protein in pRB(−), p16INK4A(+) Tumor Cells. Journal of Biological Chemistry 275:39, pages 30317-30325.
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Jacqueline L. Bruce, Robert K. HurfordJr.Jr., Marie Classon, James Koh & Nicholas Dyson. (2000) Requirements for Cell Cycle Arrest by p16INK4a. Molecular Cell 6:3, pages 737-742.
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Olle Sangfelt, Sven Erickson, Juan Castro, Thomas Heiden, Anna Gustafsson, Stefan Einhorn & Dan Grandér. (1999) Molecular mechanisms underlying interferon-α-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins. Oncogene 18:18, pages 2798-2810.
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Evan F. Lind, Jay Wayne, Qi-Zhi Wang, Teodora Staeva, Amy Stolzer & Howard T. Petrie. (1999) Bcl-2-Induced Changes in E2F Regulatory Complexes Reveal the Potential for Integrated Cell Cycle and Cell Death Functions. The Journal of Immunology 162:9, pages 5374-5379.
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