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Myrna Candelaria & Alfonso Dueñas-Gonzalez. (2015) Therapy-related myelodysplastic syndrome. Expert Opinion on Drug Safety 14:5, pages 655-665.
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Genyan Yang, Waleed Khalaf, Louis van de Locht, Joop H. Jansen, Meihua Gao, Mary Ann Thompson, Bert A. van der Reijden, David H. Gutmann, Ruud Delwel, D. Wade Clapp & Scott W. Hiebert. (2005) Transcriptional Repression of the Neurofibromatosis-1 Tumor Suppressor by the t(8;21) Fusion Protein. Molecular and Cellular Biology 25:14, pages 5869-5879.
Read now
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Kyungsil Yoon & Robert C. Smart. (2004) C/EBPα Is a DNA Damage-Inducible p53-Regulated Mediator of the G1 Checkpoint in Keratinocytes. Molecular and Cellular Biology 24:24, pages 10650-10660.
Read now
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Carsten Müller-Tidow, Björn Steffen, Thomas Cauvet, Lara Tickenbrock, Ping Ji, Sven Diederichs, Bülent Sargin, Gabriele Köhler, Matthias Stelljes, Elena Puccetti, Martin Ruthardt, Sven deVos, Scott W. Hiebert, H. Phillip Koeffler, Wolfgang E. Berdel & Hubert Serve. (2004) Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells. Molecular and Cellular Biology 24:7, pages 2890-2904.
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Joëlle Michaud, Hamish S. Scott & Robert Escher. (2003) AML1 Interconnected Pathways of Leukemogenesis. Cancer Investigation 21:1, pages 105-136.
Read now
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Jane B. Lian, Janet L. Stein, Gary S. Stein, André J. van Wijnen, Martin Montecino, Amjad Javed, Soraya Gutierrez, Jiali Shen, S. Kaleem Zaidi & Hicham Drissi. (2003) Runx2/Cbfa1 Functions: Diverse Regulation of Gene Transcription by Chromatin Remodeling and Co-Regulatory Protein Interactions. Connective Tissue Research 44:1, pages 141-148.
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Janki Rangatia, Rajani Kanth Vangala, Nicolai Treiber, Pu Zhang, Hanna Radomska, Daniel G. Tenen, Wolfgang Hiddemann & Gerhard Behre. (2002) Downregulation of c-Jun Expression by Transcription Factor C/EBPα Is Critical for Granulocytic Lineage Commitment. Molecular and Cellular Biology 22:24, pages 8681-8694.
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Jennifer J. Westendorf, S. Kaleem Zaidi, Jonathan E. Cascino, Rachel Kahler, André J. van Wijnen, Jane B. Lian, Minoru Yoshida, Gary S. Stein & Xiaodong Li. (2002) Runx2 (Cbfa1, AML-3) Interacts with Histone Deacetylase 6 and Represses the p21 Promoter. Molecular and Cellular Biology 22:22, pages 7982-7992.
Read now
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Chi Wai So & Michael L. Cleary. (2002) MLL-AFX Requires the Transcriptional Effector Domains of AFX To Transform Myeloid Progenitors and Transdominantly Interfere with Forkhead Protein Function. Molecular and Cellular Biology 22:18, pages 6542-6552.
Read now
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Cristina G. de Guzman, Alan J. Warren, Zheng Zhang, Larry Gartland, Paul Erickson, Harry Drabkin, Scott W. Hiebert & Christopher A. Klug. (2002) Hematopoietic Stem Cell Expansion and Distinct Myeloid Developmental Abnormalities in a Murine Model of the AML1-ETO Translocation. Molecular and Cellular Biology 22:15, pages 5506-5517.
Read now
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Joseph M. Amann, John Nip, David K. Strom, Bart Lutterbach, Hironori Harada, Noel Lenny, James R. Downing, Shari Meyers & Scott W. Hiebert. (2001) ETO, a Target of t(8;21) in Acute Leukemia, Makes Distinct Contacts with Multiple Histone Deacetylases and Binds mSin3A through Its Oligomerization Domain. Molecular and Cellular Biology 21:19, pages 6470-6483.
Read now
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Sebastien A. Burel, Nari Harakawa, Liming Zhou, Thomas Pabst, Daniel G. Tenen & Dong-Er Zhang. (2001) Dichotomy of AML1-ETO Functions: Growth Arrest versus Block of Differentiation. Molecular and Cellular Biology 21:16, pages 5577-5590.
Read now
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Randy Fenrick, Lilin Wang, John Nip, Joseph M. Amann, Robert J. Rooney, Jennifer Walker-Daniels, Howard C. Crawford, Diana L. Hulboy, Michael S. Kinch, Lynn M. Matrisian & Scott W. Hiebert. (2000) TEL, a Putative Tumor Suppressor, Modulates Cell Growth and Cell Morphology of Ras-Transformed Cells While Repressing the Transcription of stromelysin-1. Molecular and Cellular Biology 20:16, pages 5828-5839.
Read now
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Ari M. Melnick, Jennifer J. Westendorf, Adam Polinger, Graeme W. Carlile, Sally Arai, Helen J. Ball, Bart Lutterbach, Scott W. Hiebert & Jonathan D. Licht. (2000) The ETO Protein Disrupted in t(8;21)-Associated Acute Myeloid Leukemia Is a Corepressor for the Promyelocytic Leukemia Zinc Finger Protein. Molecular and Cellular Biology 20:6, pages 2075-2086.
Read now
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Jürgen Krauter, Gerhard Heil & Arnold Ganser. (2000) The AML1/MTG8 Fusion Transcript in t(8;21) Positive AML and its Implication for the Detection of Minimal Residual Disease. Hematology 5:5, pages 369-381.
Read now
Read now
Randy Fenrick, Joseph M. Amann, Bart Lutterbach, Lilin Wang, Jennifer J. Westendorf, James R. Downing & Scott W. Hiebert. (1999) Both TEL and AML-1 Contribute Repression Domains to the t(12;21) Fusion Protein. Molecular and Cellular Biology 19:10, pages 6566-6574.
Read now
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Shifeng Mao, Richard C. Frank, Jin Zhang, Yasushi Miyazaki & Stephen D. Nimer. (1999) Functional and Physical Interactions between AML1 Proteins and an ETS Protein, MEF: Implications for the Pathogenesis of t(8;21)-Positive Leukemias. Molecular and Cellular Biology 19:5, pages 3635-3644.
Read now
Read now
Neeraj Adya, Terryl Stacy, Nancy A. Speck & Pu Paul Liu. (1998) The Leukemic Protein Core Binding Factor β (CBFβ)–Smooth-Muscle Myosin Heavy Chain Sequesters CBFα2 into Cytoskeletal Filaments and Aggregates. Molecular and Cellular Biology 18:12, pages 7432-7443.
Read now
Read now
Vania Gelmetti, Jinsong Zhang, Mirco Fanelli, Saverio Minucci, Pier Giuseppe Pelicci & Mitchell A. Lazar. (1998) Aberrant Recruitment of the Nuclear Receptor Corepressor-Histone Deacetylase Complex by the Acute Myeloid Leukemia Fusion Partner ETO. Molecular and Cellular Biology 18:12, pages 7185-7191.
Read now
Read now
Bart Lutterbach, Jennifer J. Westendorf, Bryan Linggi, Andrea Patten, Mariko Moniwa, James R. Davie, Khanh D. Huynh, Vivian J. Bardwell, Robert M. Lavinsky, Michael G. Rosenfeld, Christopher Glass, Edward Seto & Scott W. Hiebert. (1998) ETO, a Target of t(8;21) in Acute Leukemia, Interacts with the N-CoR and mSin3 Corepressors. Molecular and Cellular Biology 18:12, pages 7176-7184.
Read now
Read now
Bart Lutterbach, Daxi Sun, John Schuetz & Scott W. Hiebert. (1998) The MYND Motif Is Required for Repression of Basal Transcription from the Multidrug Resistance 1 Promoter by the t(8;21) Fusion Protein. Molecular and Cellular Biology 18:6, pages 3604-3611.
Read now
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Crossref
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Crossref
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Crossref
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Crossref
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Na LiuJunhong SongYangyang XieXiao-Lin WangBowen RongNa ManMeng-Meng ZhangQunling ZhangFei-Fei GaoMei-Rong DuYing ZhangJian ShenChun-Hui XuCheng-Long HuJi-Chuan WuPing LiuYuan-Liang ZhangYin-Yin XiePing LiuJin-Yan Huang, Qiu-Hua HuangFei LanShuhong ShenStephen D. NimerZhu ChenSai-Juan ChenRobert G. Roeder, Lan WangXiao-Jian Sun. (2018) Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis. Proceedings of the National Academy of Sciences 116:3, pages 890-899.
Crossref
Crossref
J. N. Nichol, M. Kinal & W. H. MillerJr.Jr.. 2018. Neoplastic Diseases of the Blood. Neoplastic Diseases of the Blood
161
177
.
J A Pulikkan, D G Tenen & G Behre. (2017) C/EBPα deregulation as a paradigm for leukemogenesis. Leukemia 31:11, pages 2279-2285.
Crossref
Crossref
Maria Adamaki, Spiros Vlahopoulos, George I Lambrou, Athanasios G Papavassiliou & Maria Moschovi. (2017)
Aberrant
AML1
gene expression in the diagnosis of childhood leukemias not characterized by
AML1
-involved cytogenetic abnormalities
. Tumor Biology 39:3, pages 101042831769430.
Crossref
Crossref
Lei Zhou, Qian Wang, Xiaosu Chen, Lin Fu, Xiaodong Zhang, Lijun Wang, Ailing Deng, Dandan Li, Jing Liu, Na Lv, Lili Wang, Yonghui Li, Daihong Liu, Li Yu & Liping Dou. (2017) AML1–ETO promotes SIRT1 expression to enhance leukemogenesis of t(8;21) acute myeloid leukemia. Experimental Hematology 46, pages 62-69.
Crossref
Crossref
S Weng, S Matsuura, C T Mowery, S A Stoner, K Lam, D Ran, A G Davis, M-C Lo & D-E Zhang. (2016) Restoration of MYC-repressed targets mediates the negative effects of GM-CSF on RUNX1-ETO leukemogenicity. Leukemia 31:1, pages 159-169.
Crossref
Crossref
Ryo Amano, Kenta Takada, Yoichiro Tanaka, Yoshikazu Nakamura, Gota Kawai, Tomoko Kozu & Taiichi Sakamoto. (2016) Kinetic and Thermodynamic Analyses of Interaction between a High-Affinity RNA Aptamer and Its Target Protein. Biochemistry 55:45, pages 6221-6229.
Crossref
Crossref
Jian Li, Chun Guo, Nickolas Steinauer & Jinsong Zhang. (2016) New insights into transcriptional and leukemogenic mechanisms of AML1-ETO and E2A fusion proteins. Frontiers in Biology 11:4, pages 285-304.
Crossref
Crossref
Naidu M. Vegi, Josef Klappacher, Franz Oswald, Medhanie A. Mulaw, Amit Mandoli, Verena N. Thiel, Shiva Bamezai, Kristin Feder, Joost H.A. Martens, Vijay P.S. Rawat, Tamoghna Mandal, Leticia Quintanilla-Martinez, Karsten Spiekermann, Wolfgang Hiddemann, Konstanze Döhner, Hartmut Döhner, Hendrik G. Stunnenberg, Michaela Feuring-Buske & Christian Buske. (2016) MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML. Cell Reports 16:2, pages 498-507.
Crossref
Crossref
Hui Hui, Xiaoxiao Zhang, Hui Li, Xiao Liu, Le Shen, Yu Zhu, Jingyan Xu, Qinglong Guo & Na Lu. (2016) Oroxylin A, a natural anticancer flavonoid compound, induces differentiation of t(8;21)-positive Kasumi-1 and primary acute myeloid leukemia cells. Journal of Cancer Research and Clinical Oncology 142:7, pages 1449-1459.
Crossref
Crossref
John P. McGrath, Kaylyn E. Williamson, Srividya Balasubramanian, Shobu Odate, Shilpi Arora, Charlie Hatton, Thomas M. Edwards, Thomas O'Brien, Steven Magnuson, David Stokoe, Danette L. Daniels, Barbara M. Bryant & Patrick Trojer. (2016) Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes. Cancer Research 76:7, pages 1975-1988.
Crossref
Crossref
Yizhen LiHuanwei WangXiaoling WangWen JinYun TanHai Fang, Saijuan Chen, Zhu Chen & Kankan Wang. (2016) Genome-wide studies identify a novel interplay between AML1 and AML1/ETO in t(8;21) acute myeloid leukemia. Blood 127:2, pages 233-242.
Crossref
Crossref
LIMENGMENG WANG, HAOWEN XIAO, XING ZHANG, WEICHAO LIAO, SHAN FU & HE HUANG. (2015) Restoration of CCAAT enhancer binding protein α P42 induces myeloid differentiation and overcomes all-trans retinoic acid resistance in human acute promyelocytic leukemia NB4-R1 cells. International Journal of Oncology 47:5, pages 1685-1695.
Crossref
Crossref
Nuri Yigit, Shannon Covey, Sharon Barouk-Fox, Turker Turker, Julia Turbiner Geyer & Attilio Orazi. (2015) Nuclear factor-erythroid 2, nerve growth factor receptor, and CD34–microvessel density are differentially expressed in primary myelofibrosis, polycythemia vera, and essential thrombocythemia. Human Pathology 46:8, pages 1217-1225.
Crossref
Crossref
Joseph F. Collin, James W. Wells, Barbara Czepulkowski, Linden Lyne, Patrick J. Duriez, Alison H. Banham, Ghulam J. Mufti & Barbara-ann Guinn. (2015)
A novel zinc finger gene,
ZNF465
, is inappropriately expressed in acute myeloid leukaemia cells
. Genes, Chromosomes and Cancer 54:5, pages 288-302.
Crossref
Crossref
Sara Montagner, Lorenzo Dehó & Silvia Monticelli. (2014) MicroRNAs in hematopoietic development. BMC Immunology 15:1.
Crossref
Crossref
Krista L. Bledsoe, Meghan E. McGee-Lawrence, Emily T. Camilleri, Xiaoke Wang, Scott M. Riester, Andre J. van Wijnen, Andre M. Oliveira & Jennifer J. Westendorf. (2014) RUNX3 Facilitates Growth of Ewing Sarcoma Cells. Journal of Cellular Physiology 229:12, pages 2049-2056.
Crossref
Crossref
Xiaoke Wang, Krista L Bledsoe, Rondell P Graham, Yan W Asmann, David S Viswanatha, Jean E Lewis, Jason T Lewis, Margaret M Chou, Michael J Yaszemski, Jin Jen, Jennifer J Westendorf & André M Oliveira. (2014) Recurrent PAX3-MAML3 fusion in biphenotypic sinonasal sarcoma. Nature Genetics 46:7, pages 666-668.
Crossref
Crossref
Michael BotsInge VerbruggeBenjamin P. MartinJessica M. SalmonMargherita GhisiAdele BakerKym StanleyJake ShorttGert J. OssenkoppeleJohannes ZuberAmy R. RappaportPeter Atadja, Scott W. LoweRicky W. Johnstone. (2014) Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors. Blood 123:9, pages 1341-1352.
Crossref
Crossref
Neemat Kassem, Abd El-Gawad Fahmy, Mohamed Desoky, Nashwa Medhat & Hamdy M. Zawam. (2013) CCAAT/enhancer binding protein α gene expression in Egyptian patients with acute myeloid leukemia. Journal of the Egyptian National Cancer Institute 25:3, pages 115-120.
Crossref
Crossref
Xiao-Jian Sun, Zhanxin Wang, Lan Wang, Yanwen Jiang, Nils Kost, T. David Soong, Wei-Yi Chen, Zhanyun Tang, Tomoyoshi Nakadai, Olivier Elemento, Wolfgang Fischle, Ari Melnick, Dinshaw J. Patel, Stephen D. Nimer & Robert G. Roeder. (2013) A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis. Nature 500:7460, pages 93-97.
Crossref
Crossref
P Pal, S Lochab, J K Kanaujiya, I Kapoor, S Sanyal, G Behre & A K Trivedi. (2013) E6AP, an E3 ubiquitin ligase negatively regulates granulopoiesis by targeting transcription factor C/EBPα for ubiquitin-mediated proteasome degradation. Cell Death & Disease 4:4, pages e590-e590.
Crossref
Crossref
W Jin, K Wu, Y-Z Li, W-T Yang, B Zou, F Zhang, J Zhang & K-K Wang. (2012) AML1-ETO targets and suppresses cathepsin G, a serine protease, which is able to degrade AML1-ETO in t(8;21) acute myeloid leukemia. Oncogene 32:15, pages 1978-1987.
Crossref
Crossref
Jessica N. Nichol, Sarit Assouline & Wilson H. Miller. 2013. Neoplastic Diseases of the Blood. Neoplastic Diseases of the Blood
177
198
.
Gerald B. W. Wertheim, Elizabeth Hexner & Adam Bagg. (2012) Molecular-Based Classification of Acute Myeloid Leukemia and Its Role in Directing Rational Therapy. Molecular Diagnosis & Therapy 16:6, pages 357-369.
Crossref
Crossref
E. N. Markova, N. V. Petrova, S. V. Razin & O. L. Kantidze. (2012) Transcription factor RUNX1. Molecular Biology 46:6, pages 755-767.
Crossref
Crossref
V Grossmann, U Bacher, A Kohlmann, K Butschalowski, A Roller, S Jeromin, F Dicker, W Kern, S Schnittger, T Haferlach & C Haferlach. (2012) Expression of CEBPA is reduced in RUNX1-mutated acute myeloid leukemia. Blood Cancer Journal 2:8, pages e86-e86.
Crossref
Crossref
Robert B. Lorsbach. 2011. Diagnostic Pediatric Hematopathology. Diagnostic Pediatric Hematopathology
272
309
.
H Sill, W Olipitz, A Zebisch, E Schulz & A Wölfler. (2011) Therapy-related myeloid neoplasms: pathobiology and clinical characteristics. British Journal of Pharmacology 162:4, pages 792-805.
Crossref
Crossref
Håkon Reikvam, Kimberley Joanne Hatfield, Astrid Olsnes Kittang, Randi Hovland & Øystein Bruserud. (2011) Acute Myeloid Leukemia with the t(8;21) Translocation: Clinical Consequences and Biological Implications. Journal of Biomedicine and Biotechnology 2011, pages 1-23.
Crossref
Crossref
Matteo Brioschi, John Fischer, Roberto Cairoli, Stefano Rossetti, Laura Pezzetti, Michele Nichelatti, Mauro Turrini, Francesca Corlazzoli, Barbara Scarpati, Enrica Morra, Nicoletta Sacchi & Alessandro Beghini. (2010) Down-regulation of MicroRNAs 222/221 in Acute Myelogenous Leukemia with Deranged Core-Binding Factor Subunits. Neoplasia 12:11, pages 866-IN3.
Crossref
Crossref
Maria Rosa Lidonnici, Alessandra Audia, Angela Rachele Soliera, Marco Prisco, Giovanna Ferrari-Amorotti, Todd Waldron, Nick Donato, Ying Zhang, Robert V. Martinez, Tessa L. Holyoake & Bruno Calabretta. (2010) Expression of the Transcriptional Repressor Gfi-1 Is Regulated by C/EBPα and Is Involved in Its Proliferation and Colony Formation–Inhibitory Effects in p210BCR/ABL-Expressing Cells. Cancer Research 70:20, pages 7949-7959.
Crossref
Crossref
Giovanna Ferrari-Amorotti, Samanta Antonella Mariani, Chiara Novi, Sara Cattelani, Luisa Pecorari, Francesca Corradini, Angela Rachele Soliera, Gloria Manzotti, Valentina Fragliasso, Ying Zhang, Robert V. Martinez, Eric W.-F. Lam, Clara Guerzoni & Bruno Calabretta. (2010) The Biological Effects of C/EBPα in K562 Cells Depend on the Potency of the N-terminal Regulatory Region, Not on Specificity of the DNA Binding Domain. Journal of Biological Chemistry 285:40, pages 30837-30850.
Crossref
Crossref
Sheo Mohan Singh, Arun Kumar Trivedi, Savita Lochab, Maximilian Christopeit, Wolfgang Hiddemann & Gerhard Behre. (2010) Proteomics of AML1/ETO Target Proteins: AML1–ETO Targets a C/EBP–NM23 Pathway. Clinical Proteomics 6:3, pages 83-91.
Crossref
Crossref
Wei Wang, Sven Schwemmers, Elizabeth O. Hexner & Heike L. Pahl. (2010) AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2. Blood 116:2, pages 254-266.
Crossref
Crossref
Xiaopei Huang & Yiping Yang. 2010. Molecular Pathology of Hematolymphoid Diseases. Molecular Pathology of Hematolymphoid Diseases
81
89
.
Pallavi Gupta, Gangenahalli U. Gurudutta, Daman Saluja & Rajendra P. Tripathi. (2009) PU.1 and partners: regulation of haematopoietic stem cell fate in normal and malignant haematopoiesis. Journal of Cellular and Molecular Medicine 13:11-12, pages 4349-4363.
Crossref
Crossref
Meng Zhao, Xu-Fang Duan, Xu-Yun Zhao, Bo Zhang, Ying Lu, Wei Liu, Jin-Ke Cheng & Guo-Qiang Chen. (2009) Protein Kinase Cδ Stimulates Proteasome-Dependent Degradation of C/EBPα during Apoptosis Induction of Leukemic Cells. PLoS ONE 4:8, pages e6552.
Crossref
Crossref
Mònica Arman, Noemí Aguilera-Montilla, Virgínia Mas, Amaya Puig-Kröger, Miguel Pignatelli, Roderic Guigó, Angel-Luis Corbí & Francisco Lozano. (2009) The human CD6 gene is transcriptionally regulated by RUNX and Ets transcription factors in T cells. Molecular Immunology 46:11-12, pages 2226-2235.
Crossref
Crossref
Patrick C. Hanington, Jonathan Tam, Barbara A. Katzenback, Steven J. Hitchen, Daniel R. Barreda & Miodrag Belosevic. (2009) Development of macrophages of cyprinid fish. Developmental & Comparative Immunology 33:4, pages 411-429.
Crossref
Crossref
Jennifer J. Clark, Jason N. Berman & A. Thomas Look. 2009. Oncology of Infancy and Childhood. Oncology of Infancy and Childhood
331
402
.
Michael E. Engel & Scott W. Hiebert. 2010. Acute Myelogenous Leukemia. Acute Myelogenous Leukemia
127
147
.
M Andreeff, V Ruvolo, S Gadgil, C Zeng, K Coombes, W Chen, S Kornblau, A E Barón & H A Drabkin. (2008) HOX expression patterns identify a common signature for favorable AML. Leukemia 22:11, pages 2041-2047.
Crossref
Crossref
Mumtaz Yaseen Balkhi, Maximilian Christopeit, Yong Chen, Mulu Geletu & Gerhard Behre. (2008) AML1/ETO–induced survivin expression inhibits transcriptional regulation of myeloid differentiation. Experimental Hematology 36:11, pages 1449-1460.e1.
Crossref
Crossref
Maria J. Carnicer, Adriana Lasa, Marcus Buschbeck, Elena Serrano, Maite Carricondo, Salut Brunet, Anna Aventin, Jorge Sierra, Luciano Di Croce & Josep F. Nomdedeu. (2008) K313dup is a recurrent CEBPA mutation in de novo acute myeloid leukemia (AML). Annals of Hematology 87:10, pages 819-827.
Crossref
Crossref
Wenbin Liu, Fei Yang, Shihai Jia, Xuexia Miao & Yongping Huang. (2008)
Cloning and characterization of
Bmrunt
from the silkworm
Bombyx mori
during embryonic development
. Archives of Insect Biochemistry and Physiology 69:2, pages 47-59.
Crossref
Crossref
Rose M. Ko, Hyung-Gyoon Kim, Linda Wolff & Christopher A. Klug. (2008) Roles of p15Ink4b and p16Ink4a in myeloid differentiation and RUNX1-ETO-associated acute myeloid leukemia. Leukemia Research 32:7, pages 1101-1111.
Crossref
Crossref
A.K. Trivedi, P. Pal, G. Behre & S.M. Singh. (2008) Multiple ways of C/EBPα inhibition in myeloid leukaemia. European Journal of Cancer 44:11, pages 1516-1523.
Crossref
Crossref
Hui Wei, Xiangrong Liu, Xiujuan Xiong, Yang Wang, Qing Rao, Min Wang & Jianxiang Wang. (2008) AML1-ETO interacts with Sp1 and antagonizes Sp1 transactivity through RUNT domain. FEBS Letters 582:15, pages 2167-2172.
Crossref
Crossref
Catherine Roche-LestienneLauréline DelucheSélim CormIsabelle TigaudSami JohaNathalie Philippe, Sandrine Geffroy, Jean-Luc LaïFranck-Emmanuel Nicolini & Claude Preudhomme. (2008) RUNX1 DNA-binding mutations and RUNX1-PRDM16 cryptic fusions in BCR-ABL+ leukemias are frequently associated with secondary trisomy 21 and may contribute to clonal evolution and imatinib resistance. Blood 111:7, pages 3735-3741.
Crossref
Crossref
Inken Wierstra & Jürgen Alves. 2008.
113
333
.
A Tonks, L Pearn, M Musson, A Gilkes, K I Mills, A K Burnett & R L Darley. (2007) Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia. Leukemia 21:12, pages 2495-2505.
Crossref
Crossref
Hein Schepers, Albertus T. J. WierengaDjoke van GosligaBart J. L. Eggen, Edo VellengaJan Jacob Schuringa. (2007) Reintroduction of C/EBPα in leukemic CD34+ stem/progenitor cells impairs self-renewal and partially restores myelopoiesis. Blood 110:4, pages 1317-1325.
Crossref
Crossref
Y Tabe, L Jin, R Contractor, D Gold, P Ruvolo, S Radke, Y Xu, Y Tsutusmi-Ishii, K Miyake, N Miyake, S Kondo, A Ohsaka, I Nagaoka, M Andreeff & M Konopleva. (2007) Novel role of HDAC inhibitors in AML1/ETO AML cells: activation of apoptosis and phagocytosis through induction of annexin A1. Cell Death & Differentiation 14:8, pages 1443-1456.
Crossref
Crossref
Claus Nerlov. (2007) The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation control. Trends in Cell Biology 17:7, pages 318-324.
Crossref
Crossref
N. M. Yartseva, R. F. Fedortseva & I. V. Artsybasheva. (2007) Chromosomal rearrangements and their role in spontaneous immortalization and transformation of rat embryo cells in vitro. Cell and Tissue Biology 1:3, pages 259-271.
Crossref
Crossref
Malene Bjerregaard Pass, Niels Borregaard & Jack Bernard Cowland. (2007) Derangement of transcription factor profiles during in vitro differentiation of HL60 and NB4 cells. Leukemia Research 31:6, pages 827-837.
Crossref
Crossref
A K Trivedi, D Bararia, M Christopeit, A A PeerZada, S M Singh, A Kieser, W Hiddemann, H M Behre & G Behre. (2006) Proteomic identification of C/EBP-DBD multiprotein complex: JNK1 activates stem cell regulator C/EBPα by inhibiting its ubiquitination. Oncogene 26:12, pages 1789-1801.
Crossref
Crossref
S Jäger, A Jahnke, T Wilmes, S Adebahr, F-N Vögtle, E deLima-Hahn, D Pfeifer, T Berg, M Lübbert & M Trepel. (2007) Leukemia targeting ligands isolated from phage display peptide libraries. Leukemia 21:3, pages 411-420.
Crossref
Crossref
Giuseppe Mameli, Satish L. Deshmane, Mohammad Ghafouri, Jianqi Cui, Kenneth Simbiri, Kamel Khalili, Ruma Mukerjee, Antonina Dolei, Shohreh Amini & Bassel E. Sawaya. (2007) C/EBPβ regulates human immunodeficiency virus 1 gene expression through its association with cdk9. Journal of General Virology 88:2, pages 631-640.
Crossref
Crossref
Jörg Cammenga, Birte Niebuhr, Stefan Horn, Ulla Bergholz, Gabriele Putz, Frank Buchholz, Jürgen Löhler & Carol Stocking. (2007) RUNX1 DNA-Binding Mutants, Associated with Minimally Differentiated Acute Myelogenous Leukemia, Disrupt Myeloid Differentiation. Cancer Research 67:2, pages 537-545.
Crossref
Crossref
Karen Keeshan, Yiping He, Bas J. Wouters, Olga Shestova, Lanwei Xu, Hong Sai, Carlos G. Rodriguez, Ivan Maillard, John W. Tobias, Peter Valk, Martin Carroll, Jon C. Aster, Ruud Delwel & Warren S. Pear. (2006) Tribbles homolog 2 inactivates C/EBPα and causes acute myelogenous leukemia. Cancer Cell 10:5, pages 401-411.
Crossref
Crossref
J Dunne, C Cullmann, M Ritter, N Martinez Soria, B Drescher, S Debernardi, S Skoulakis, O Hartmann, M Krause, J Krauter, A Neubauer, B D Young & O Heidenreich. (2006) siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts. Oncogene 25:45, pages 6067-6078.
Crossref
Crossref
Xi Li, Ya-Bei Xu, Qiong Wang, Ying Lu, Ying Zheng, Ying-Chao Wang, Michael Lübbert, Ke-Wen Zhao & Guo-Qiang Chen. (2006) Leukemogenic AML1-ETO fusion protein upregulates expression of connexin 43: The role in AML1-ETO-induced growth arrest in leukemic cells. Journal of Cellular Physiology 208:3, pages 594-601.
Crossref
Crossref
Mikkel Bruhn Schuster & Bo Torben Porse. (2006) C/EBPα: A tumour suppressor in multiple tissues?. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1766:1, pages 88-103.
Crossref
Crossref
Amaya Puig-Kröger & Angel Corbí. (2006) RUNX3: A new player in myeloid gene expression and immune response. Journal of Cellular Biochemistry 98:4, pages 744-756.
Crossref
Crossref
Zongfei Yuan, Angela Tie, Mark Tarnopolsky & Marica Bakovic. (2006) Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1. Physiological Genomics 26:1, pages 76-90.
Crossref
Crossref
Fady M. Mikhail, Kislay K. Sinha, Yogen Saunthararajah & Giuseppina Nucifora. (2006) Normal and transforming functions of RUNX1: A perspective. Journal of Cellular Physiology 207:3, pages 582-593.
Crossref
Crossref
Sumiyuki NishidaNaoki HosenToshiaki ShirakataKeisuke KanatoMasashi YanagiharaShin-ichi NakatsukaYoshihiko HoshidaTsutomu NakazawaYukie HaradaNaoya TatsumiAkihiro TsuboiManabu KawakamiYoshihiro OkaYusuke OjiKatsuyuki AozasaIchiro KawaseHaruo Sugiyama. (2006) AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1. Blood 107:8, pages 3303-3312.
Crossref
Crossref
J Lausen, S Liu, M Fliegauf, M Lübbert & M H Werner. (2005) ELA2 is regulated by hematopoietic transcription factors, but not repressed by AML1-ETO. Oncogene 25:9, pages 1349-1357.
Crossref
Crossref
Maria THOMAS, Johann GREIL & Olaf HEIDENREICH. (2006) Targeting leukemic fusion proteins with small interfering RNAs: recent advances and therapeutic potentials1. Acta Pharmacologica Sinica 27:3, pages 273-281.
Crossref
Crossref
Hanna S. Radomska, Daniela S. Bassères, Rui Zheng, Pu Zhang, Tajhal Dayaram, Yukiya Yamamoto, David W. Sternberg, Nathalie Lokker, Neill A. Giese, Stefan K. Bohlander, Susanne Schnittger, Marie-Hélène Delmotte, Roger J. Davis, Donald Small, Wolfgang Hiddemann, D. Gary Gilliland & Daniel G. Tenen. (2006) Block of C/EBPα function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations. Journal of Experimental Medicine 203:2, pages 371-381.
Crossref
Crossref
Robert B. Lorsbach & James R. Downing. 2010. Childhood Leukemias. Childhood Leukemias
298
338
.
Jun Qian, Zixing Chen, Jiang Lin, Wei Wang & Jiannong Cen. (2005) Decreased expression of CCAAT/enhancer binding protein ζ (C/EBPζ) in patients with different myeloid diseases. Leukemia Research 29:12, pages 1435-1441.
Crossref
Crossref
Meike Fischer, Maike Schwieger, Stefan Horn, Birte Niebuhr, Anthony Ford, Susanne Roscher, Ulla Bergholz, Mel Greaves, Jürgen Löhler & Carol Stocking. (2005) Defining the oncogenic function of the TEL/AML1 (ETV6/RUNX1) fusion protein in a mouse model. Oncogene 24:51, pages 7579-7591.
Crossref
Crossref
Björn Steffen, Carsten Müller-Tidow, Joachim Schwäble, Wolfgang E. Berdel & Hubert Serve. (2005) The molecular pathogenesis of acute myeloid leukemia. Critical Reviews in Oncology/Hematology 56:2, pages 195-221.
Crossref
Crossref
Sigal GeryAdrian F. GombartWilliam S. YiChloe KoefflerWolf-K. HofmannH. Phillip Koeffler. (2005) Transcription profiling of C/EBP targets identifies Per2 as a gene implicated in myeloid leukemia. Blood 106:8, pages 2827-2836.
Crossref
Crossref
Joseph D. GrowneyHirokazu ShigematsuZhe LiBenjamin H. LeeJennifer AdelspergerRebecca RowanDavid P. CurleyJeffery L. KutokKoichi AkashiIfor R. WilliamsNancy A. SpeckD. Gary Gilliland. (2005) Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype. Blood 106:2, pages 494-504.
Crossref
Crossref
Bo T. Porse, David Bryder, Kim Theilgaard-Mönch, Marie S. Hasemann, Kristina Anderson, Inge Damgaard, Sten Eirik W. Jacobsen & Claus Nerlov. (2005) Loss of C/EBPα cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage. Journal of Experimental Medicine 202:1, pages 85-96.
Crossref
Crossref
Chunaram ChoudharyJoachim SchwäbleChristian BrandtsLara TickenbrockBülent SarginThomas KindlerThomas FischerWolfgang E. BerdelCarsten Müller-TidowHubert Serve. (2005) AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations. Blood 106:1, pages 265-273.
Crossref
Crossref
Y Jiang, Z-H Xue, W-Z Shen, K-M Du, H Yan, Y Yu, Z-G Peng, M-G Song, J-H Tong, Z Chen, Y Huang, M Lübbert & G-Q Chen. (2005) Desferrioxamine induces leukemic cell differentiation potentially by hypoxia-inducible factor-1α that augments transcriptional activity of CCAAT/enhancer-binding protein-α. Leukemia 19:7, pages 1239-1247.
Crossref
Crossref
S. V. Razin & O. V. Iarovaia. (2005) Spatial Organization of DNA in the Nucleus May Determine Positions of Recombination Hot Spots. Molecular Biology 39:4, pages 543-548.
Crossref
Crossref
Gurudutta U. GangenahalliPallavi GuptaDaman SalujaYogesh K. VermaVimal KishoreRamesh ChandraR.K. SharmaT. Ravindranath. (2005) Stem Cell Fate Specification: Role of Master Regulatory Switch Transcription Factor PU.1 in Differential Hematopoiesis. Stem Cells and Development 14:2, pages 140-152.
Crossref
Crossref
Hong Yin, Mylinh Smith & Jonathan Glass. (2005) Stable expression of C/EBP? in prostate cancer cells down-regulates metallothionein and increases zinc-induced toxicity. The Prostate 62:3, pages 209-216.
Crossref
Crossref
Minsub Shim, Kristina L. Powers, Sarah J. Ewing, Songyun Zhu & Robert C. Smart. (2005) Diminished Expression of C/EBPα in Skin Carcinomas Is Linked to Oncogenic Ras and Reexpression of C/EBPα in Carcinoma Cells Inhibits Proliferation. Cancer Research 65:3, pages 861-867.
Crossref
Crossref
Alan G. Rosmarin, Zhongfa Yang & Karen K. Resendes. (2005) Transcriptional regulation in myelopoiesis: Hematopoietic fate choice, myeloid differentiation, and leukemogenesis. Experimental Hematology 33:2, pages 131-143.
Crossref
Crossref
Manfred Fliegauf, Michael Stock, Tobias Berg & Michael Lübbert. (2004) Williams–Beuren syndrome critical region-5/non-T-cell activation linker: a novel target gene of AML1/ETO. Oncogene 23:56, pages 9070-9081.
Crossref
Crossref
Natalia Martinez, Bettina Drescher, Heidemarie Riehle, Claire Cullmann, Hans-Peter Vornlocher, Arnold Ganser, Gerhard Heil, Alfred Nordheim, Jürgen Krauter & Olaf Heidenreich. (2004) The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells. BMC Cancer 4:1.
Crossref
Crossref
Youhong Zhang, Joseph R. Biggs & Andrew S. Kraft. (2004) Phorbol Ester Treatment of K562 Cells Regulates the Transcriptional Activity of AML1c through Phosphorylation. Journal of Biological Chemistry 279:51, pages 53116-53125.
Crossref
Crossref
Misung Jo, Mary C. Gieske, Charles E. Payne, Sarah E. Wheeler-Price, Joseph B. Gieske, Ignatius V. Ignatius, Thomas E. Curry & CheMyong Ko. (2004) Development and Application of a Rat Ovarian Gene Expression Database. Endocrinology 145:11, pages 5384-5396.
Crossref
Crossref
U Testa, E Stellacci, E Pelosi, P Sestili, M Venditti, R Orsatti, A Fragale, E Petrucci, L Pasquini, F Belardelli, L Gabriele & A Battistini. (2004) Impaired myelopoiesis in mice devoid of interferon regulatory factor 1. Leukemia 18:11, pages 1864-1871.
Crossref
Crossref
Michael Centrella, Sylvia Christakos & Thomas L. McCarthy. (2004) Skeletal hormones and the C/EBP and Runx transcription factors: interactions that integrate and redefine gene expression. Gene 342:1, pages 13-24.
Crossref
Crossref
Timothy S. Fenske, Gina Pengue, Vikram Mathews, Piia T. Hanson, Sarah E. Hamm, Noor Riaz & Timothy A. Graubert. (2004) Stem cell expression of the AML1/ETO fusion protein induces a myeloproliferative disorder in mice. Proceedings of the National Academy of Sciences 101:42, pages 15184-15189.
Crossref
Crossref
Olga V. Iarovaia, Petr Shkumatov & Sergey V. Razin. (2004)
Breakpoint cluster regions of the
AML-1
and
ETO
genes contain MAR elements and are preferentially associated with the nuclear matrix in proliferating HEL cells
. Journal of Cell Science 117:19, pages 4583-4590.
Crossref
Crossref
Hisako Gunji, Kazuo Waga, Fumihiko Nakamura, Kazuhiro Maki, Ko Sasaki, Yuichi Nakamura & Kinuko Mitani. (2004) TEL/AML1 shows dominant-negative effects over TEL as well as AML1. Biochemical and Biophysical Research Communications 322:2, pages 623-630.
Crossref
Crossref
Vinzon Ibañez, Arun Sharma, Silvia Buonamici, Amit Verma, Sudhakar Kalakonda, Jianxiang Wang, ShriHari Kadkol & Yogen Saunthararajah. (2004) AML1-ETO Decreases ETO-2 (MTG16) Interactions with Nuclear Receptor Corepressor, an Effect That Impairs Granulocyte Differentiation. Cancer Research 64:13, pages 4547-4554.
Crossref
Crossref
Stefano Rossetti, André T Hoogeveen & Nicoletta Sacchi. (2004) The MTG proteins: chromatin repression players with a passion for networking. Genomics 84:1, pages 1-9.
Crossref
Crossref
Luke F Peterson & Dong-Er Zhang. (2004) The 8;21 translocation in leukemogenesis. Oncogene 23:24, pages 4255-4262.
Crossref
Crossref
Gary S Stein, Jane B Lian, Andre J van Wijnen, Janet L Stein, Martin Montecino, Amjad Javed, Sayyed K Zaidi, Daniel W Young, Je-Yong Choi & Shirwin M Pockwinse. (2004) Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression. Oncogene 23:24, pages 4315-4329.
Crossref
Crossref
Kristie L Durst & Scott W Hiebert. (2004) Role of RUNX family members in transcriptional repression and gene silencing. Oncogene 23:24, pages 4220-4224.
Crossref
Crossref
Colleen Delaney & Irwin D. Bernstein. (2004) Establishment of a pluripotent preleukaemic stem cell line by expression of the AML1-ETO fusion protein in Notch1-immortalized HSCN1cl10 cells. British Journal of Haematology 125:3, pages 353-357.
Crossref
Crossref
Je-Yoel Cho, Yasmin Akbarali, Luiz F. Zerbini, Xuesong Gu, Jay Boltax, Yihong Wang, Peter Oettgen, Dong-Er Zhang & Towia A. Libermann. (2004) Isoforms of the Ets Transcription Factor NERF/ELF-2 Physically Interact with AML1 and Mediate Opposing Effects on AML1-mediated Transcription of the B Cell-specific blk Gene. Journal of Biological Chemistry 279:19, pages 19512-19522.
Crossref
Crossref
Attaya Suvannasankha, Hans Minderman, Kieran L. O’Loughlin, Sheila N.J. Sait, Carleton C. Stewart, William R. Greco & Maria R. Baer. (2004) Expression of the neural cell adhesion molecule CD56 is not associated with P-glycoprotein overexpression in core-binding factor acute myeloid leukemia. Leukemia Research 28:5, pages 449-455.
Crossref
Crossref
Maike SchwiegerJürgen LöhlerMeike FischerUwe HerwigDaniel G. TenenCarol Stocking. (2004) A dominant-negative mutant of C/EBPα, associated with acute myeloid leukemias, inhibits differentiation of myeloid and erythroid progenitors of man but not mouse. Blood 103:7, pages 2744-2752.
Crossref
Crossref
Danilo Perrotti, Guido Marcucci & Michael A. Caligiuri. (2004) Loss of C/EBPα and Favorable Prognosis of Acute Myeloid Leukemias: A Biological Paradox. Journal of Clinical Oncology 22:4, pages 582-584.
Crossref
Crossref
Wolfgang Hiddemann, Heinz Huber & Claus R. BartramW. Kern, T. Haferlach & W. Hiddemann. 2004. Die Onkologie. Die Onkologie
1847
1915
.
Catriona H. M. Jamieson, Emmanuelle Passegué & Irving L. Weissman. 2004. Stem Cells in the Nervous System: Functional and Clinical Implications. Stem Cells in the Nervous System: Functional and Clinical Implications
157
182
.
Ian Anglin & Antonio Passaniti. 2004. Molecular Targeting and Signal Transduction. Molecular Targeting and Signal Transduction
189
215
.
Sofia Rondin Lindberg, André Olsson, Ann-Maj Persson & Inge Olsson. (2003) Interactions between the leukaemia-associated ETO homologues of nuclear repressor proteins. European Journal of Haematology 71:6, pages 439-447.
Crossref
Crossref
Michael Rehli, Hans-Helmut Niller, Christoph Ammon, Sabine Langmann, Lucia Schwarzfischer, Reinhard Andreesen & Stefan W. Krause. (2003) Transcriptional Regulation of CHI3L1, a Marker Gene for Late Stages of Macrophage Differentiation. Journal of Biological Chemistry 278:45, pages 44058-44067.
Crossref
Crossref
Andreas Lennartsson, Katrien Pieters, Tove Ullmark, Karina Vidovic & Urban Gullberg. (2003) AML-1, PU.1, and Sp3 regulate expression of human bactericidal/permeability-increasing protein. Biochemical and Biophysical Research Communications 311:4, pages 853-863.
Crossref
Crossref
Thomas L. McCarthy, Wei-Zhong Chang, Yuan Liu & Michael Centrella. (2003) Runx2 Integrates Estrogen Activity in Osteoblasts. Journal of Biological Chemistry 278:44, pages 43121-43129.
Crossref
Crossref
Irene Söderhäll, Eakaphun Bangyeekhun, Susan Mayo & Kenneth Söderhäll. (2003) Hemocyte production and maturation in an invertebrate animal; proliferation and gene expression in hematopoietic stem cells of Pacifastacus leniusculus. Developmental & Comparative Immunology 27:8, pages 661-672.
Crossref
Crossref
Christine Damm-Welk, Uta Fuchs, Wilhelm Wössmann & Arndt Borkhardt. (2003) Targeting oncogenic fusion genes in leukemias and lymphomas by RNA interference. Seminars in Cancer Biology 13:4, pages 283-292.
Crossref
Crossref
Masao MizukiJoachim SchwäbleClaudia SteurChunaram ChoudharyShuchi AgrawalBülent SarginBjörn SteffenItaru MatsumuraYuzuru KanakuraFrank D. BöhmerCarsten Müller-TidowWolfgang E. BerdelHubert Serve. (2003) Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations. Blood 101:8, pages 3164-3173.
Crossref
Crossref
Olaf HeidenreichJürgen KrauterHeidemarie RiehlePhilipp HadwigerMatthias JohnGerhard HeilHans-Peter VornlocherAlfred Nordheim. (2003) AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells. Blood 101:8, pages 3157-3163.
Crossref
Crossref
Rachel A. Kahler & Jennifer J. Westendorf. (2003) Lymphoid Enhancer Factor-1 and ॆ-Catenin Inhibit Runx2-dependent Transcriptional Activation of the Osteocalcin Promoter. Journal of Biological Chemistry 278:14, pages 11937-11944.
Crossref
Crossref
Jörg CammengaJames C. MulloyFrancisco J. BerguidoDonal MacGroganAgnes VialeStephen D. Nimer. (2003) Induction of C/EBPα activity alters gene expression and differentiation of human CD34+ cells. Blood 101:6, pages 2206-2214.
Crossref
Crossref
Beatrice U. MuellerThomas PabstMotomi OsatoNorio AsouLisa M. JohansenMark D. MindenGerhard BehreWolfgang HiddemannYoshiaki ItoDaniel G. Tenen. (2003) Heterozygous PU.1 mutations are associated with acute myeloid leukemia. Blood 101:5, pages 2074-2074.
Crossref
Crossref
Cristina G de Guzman, Amanda Johnson & Christopher A Klug. (2003) The ETO domain is necessary for the developmental abnormalities associated with AML1-ETO expression in the hematopoietic stem cell compartment in vivo. Blood Cells, Molecules, and Diseases 30:2, pages 201-206.
Crossref
Crossref
Scott W Hiebert, Edward F Reed-Inderbitzin, Joseph Amann, Brenda Irvin, Kristie Durst & Bryan Linggi. (2003) The t(8;21) fusion protein contacts co-repressors and histone deacetylases to repress the transcription of the p14ARF tumor suppressor. Blood Cells, Molecules, and Diseases 30:2, pages 177-183.
Crossref
Crossref
Daniel G. Tenen. (2003) Disruption of differentiation in human cancer: AML shows the way. Nature Reviews Cancer 3:2, pages 89-101.
Crossref
Crossref
Norio Asou. (2003) The role of a Runt domain transcription factor AML1/RUNX1 in leukemogenesis and its clinical implications. Critical Reviews in Oncology/Hematology 45:2, pages 129-150.
Crossref
Crossref
Fernando P G Silva, Bruno Morolli, Clelia T Storlazzi, Luisa Anelli, Hans Wessels, Vladimir Bezrookove, Hanneke C Kluin-Nelemans & Micheline Giphart-Gassler. (2003) Identification of RUNX1/AML1 as a classical tumor suppressor gene. Oncogene 22:4, pages 538-547.
Crossref
Crossref
C Roumier, P Fenaux, M Lafage, M Imbert, V Eclache & C Preudhomme. (2003) New mechanisms of AML1 gene alteration in hematological malignancies. Leukemia 17:1, pages 9-16.
Crossref
Crossref
S. W. Hiebert, B. Lutterbach, J. Amann, K. Durst & B. Linggi. 2003. Acute Leukemias IX. Acute Leukemias IX
21
24
.
B. Steffen, M. Ruthardt, K. Becker, S. Klümpen, M. Möller, W. E. Berdel, H. Serve & C. Müller-Tidow. 2003. Acute Leukemias IX. Acute Leukemias IX
40
43
.
Christa Fonatsch, Ilse Schwarzinger, Gerlinde Mitterbauer, Ulrich Jäger, Rotraud Wieser, Christine Mannhalter & Klaus Lechner. 2003. Molekularmedizinische Grundlagen von hämatologischen Neoplasien. Molekularmedizinische Grundlagen von hämatologischen Neoplasien
312
350
.
Ruibao Ren. (2002) The molecular mechanism of chronic myelogenous leukemia and its therapeutic implications: studies in a murine model. Oncogene 21:56, pages 8629-8642.
Crossref
Crossref
Chava Perry, Ella H Sklan, Klara Birikh, Michael Shapira, Leonor Trejo, Amiram Eldor & Hermona Soreq. (2002) Complex regulation of acetylcholinesterase gene expression in human brain tumors. Oncogene 21:55, pages 8428-8441.
Crossref
Crossref
Caroline Erter Burns, Tony DeBlasio, Yi Zhou, Jin Zhang, Leonard Zon & Stephen D Nimer. (2002) Isolation and characterization of runxa and runxb, zebrafish members of the runt family of transcriptional regulators. Experimental Hematology 30:12, pages 1381-1389.
Crossref
Crossref
Karina Barseguian, Bart Lutterbach, Scott W. Hiebert, Jeffrey Nickerson, Jane B. Lian, Janet L. Stein, Andre J. van Wijnen & Gary S. Stein. (2002) Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins. Proceedings of the National Academy of Sciences 99:24, pages 15434-15439.
Crossref
Crossref
D. Gary GillilandJames D. Griffin. (2002) The roles of FLT3 in hematopoiesis and leukemia. Blood 100:5, pages 1532-1542.
Crossref
Crossref
Louise M. KellyD. Gary Gilliland. (2002)
G
ENETICS OF
M
YELOID
L
EUKEMIAS
. Annual Review of Genomics and Human Genetics 3:1, pages 179-198.
Crossref
Crossref
D. Gary Gilliland & James D. Griffin. (2002) Role of FLT3 in leukemia. Current Opinion in Hematology 9:4, pages 274-281.
Crossref
Crossref
Nancy A. Speck & D. Gary Gilliland. (2002) Core-binding factors in haematopoiesis and leukaemia. Nature Reviews Cancer 2:7, pages 502-513.
Crossref
Crossref
Eileen S. Lee, Deba Sarma, Huiyu Zhou & Andrew J. Henderson. (2002) CCAAT/Enhancer Binding Proteins Are Not Required for HIV-1 Entry but Regulate Proviral Transcription by Recruiting Coactivators to the Long-Terminal Repeat in Monocytic Cells. Virology 299:1, pages 20-31.
Crossref
Crossref
Hugues LeroyChristophe RoumierNathalie Grardel-DuflosElizabeth MacintyrePascale LepelleyPierre FenauxClaude Preudhomme. (2002) Unlike AML1, CBFβ gene is not deregulated by point mutations in acute myeloid leukemia and in myelodysplastic syndromes. Blood 99:10, pages 3848-3850.
Crossref
Crossref
Alan D Friedman. (2002) Transcriptional regulation of granulocyte and monocyte development. Oncogene 21:21, pages 3377-3390.
Crossref
Crossref
Joseph M Scandura, Piernicola Boccuni, Jorg Cammenga & Stephen D Nimer. (2002) Transcription factor fusions in acute leukemia: variations on a theme. Oncogene 21:21, pages 3422-3444.
Crossref
Crossref
H Shimada, H Ichikawa & M Ohki. (2002) Potential involvement of the AML1-MTG8 fusion protein in the granulocytic maturation characteristic of the t(8;21) acute myelogenous leukemia revealed by microarray analysis. Leukemia 16:5, pages 874-885.
Crossref
Crossref
Stephen E. Langabeer, Rosemary E. Gale, Sara J. Rollinson, Gareth J. Morgan & David C. Linch. (2002) Mutations of theAML1 gene in acute myeloid leukemia of FAB types M0 and M7. Genes, Chromosomes and Cancer 34:1, pages 24-32.
Crossref
Crossref
Maggie L. Kalev-Zylinska, Julia A. Horsfield, Maria Vega C. Flores, John H. Postlethwait, Maria R. Vitas, Andrea M. Baas, Philip S. Crosier & Kathryn E. Crosier. (2002) Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis. Development 129:8, pages 2015-2030.
Crossref
Crossref
Cristina Mecucci, Roberto Rosati & Roberta La Starza. (2002) GENETIC PROFILE OF ACUTE MYELOID LEUKEMIA. Reviews in Clinical and Experimental Hematology 6:1, pages 3-25.
Crossref
Crossref
Chava Perry, Amiram Eldor & Hermona Soreq. (2002) Runx1/AML1 in leukemia: disrupted association with diverse protein partners. Leukemia Research 26:3, pages 221-228.
Crossref
Crossref
David G Skalnik. (2002) Transcriptional mechanisms regulating myeloid-specific genes. Gene 284:1-2, pages 1-21.
Crossref
Crossref
Songyun Zhu, Kyungsil Yoon, Esta Sterneck, Peter F. Johnson & Robert C. Smart. (2001) CCAAT/enhancer binding protein-β is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling. Proceedings of the National Academy of Sciences 99:1, pages 207-212.
Crossref
Crossref
James C. MulloyJörg CammengaKaren L. MacKenzieFrancisco J. BerguidoMalcolm A. S. MooreStephen D. Nimer. (2002) The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells. Blood 99:1, pages 15-23.
Crossref
Crossref
Danilo Perrotti, Vincenzo Cesi, Rossana Trotta, Clara Guerzoni, Giorgia Santilli, Kenneth Campbell, Angela Iervolino, Fabrizio Condorelli, Carlo Gambacorti-Passerini, Michael A. Caligiuri & Bruno Calabretta. (2001) BCR-ABL suppresses C/EBPα expression through inhibitory action of hnRNP E2. Nature Genetics 30:1, pages 48-58.
Crossref
Crossref
Grace M Cuenco & Ruibao Ren. (2001) Cooperation of BCR-ABL and AML1/MDS1/EVI1 in blocking myeloid differentiation and rapid induction of an acute myelogenous leukemia. Oncogene 20:57, pages 8236-8248.
Crossref
Crossref
Jennifer J. Westendorf. (2001) The Formin/Diaphanous-related Protein, FHOS, Interacts with Rac1 and Activates Transcription from the Serum Response Element. Journal of Biological Chemistry 276:49, pages 46453-46459.
Crossref
Crossref
Nancy Fossett & Robert A. Schulz. (2001) Functional conservation of hematopoietic factors in Drosophila and vertebrates. Differentiation 69:2-3, pages 83-90.
Crossref
Crossref
Sivasubramaniam Sudhakar, Ye Li, Michael S. Katz & Narayanasamy Elango. (2001) Translational Regulation Is a Control Point in RUNX2/Cbfa1 Gene Expression. Biochemical and Biophysical Research Communications 289:2, pages 616-622.
Crossref
Crossref
Paul M. Popernack, Linh T. Truong, Marloes Kamphuis & Andrew J. Henderson. (2001)
Ectopic Expression of CCAAT/Enhancer Binding Protein
β
(C/EBP
β
) in Long-Term Bone Marrow Cultures Induces Granulopoiesis and Alters Stromal Cell Function
. Journal of Hematotherapy & Stem Cell Research 10:5, pages 631-642.
Crossref
Crossref
Patrik Andreasson, Juerg Schwaller, Ema Anastasiadou, Jon Aster & D.Gary Gilliland. (2001) The expression of ETV6/CBFA2 (TEL/AML1) is not sufficient for the transformation of hematopoietic cell lines in vitro or the induction of hematologic disease in vivo. Cancer Genetics and Cytogenetics 130:2, pages 93-104.
Crossref
Crossref
Daniel R Barreda & Miodrag Belosevic. (2001) Transcriptional regulation of hemopoiesis. Developmental & Comparative Immunology 25:8-9, pages 763-789.
Crossref
Crossref
Jonathan D Licht. (2001) AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML. Oncogene 20:40, pages 5660-5679.
Crossref
Crossref
Yuka Harada, Hironori Harada, James R. Downing & Akiro Kimura. (2001) A Hematopoietic-Specific Transmembrane Protein, Art-1, Is Possibly Regulated by AML1. Biochemical and Biophysical Research Communications 284:3, pages 714-722.
Crossref
Crossref
DG Tenen. (2001) Abnormalities of the CEBP alpha transcription factor: a major target in acute myeloid leukemia. Leukemia 15:4, pages 688-689.
Crossref
Crossref
Thomas Pabst, Beatrice U. Mueller, Nari Harakawa, Claudia Schoch, Torsten Haferlach, Gerhard Behre, Wolfgang Hiddemann, Dong-Er Zhang & Daniel G. Tenen. (2001) AML1–ETO downregulates the granulocytic differentiation factor C/EBPα in t(8;21) myeloid leukemia. Nature Medicine 7:4, pages 444-451.
Crossref
Crossref
Scott Hiebert. (2001) Differentiation or leukemia: Is C/EBPα the answer?. Nature Medicine 7:4, pages 407-408.
Crossref
Crossref
Ajeeta Dash & D.Gary Gilliland. (2001) Molecular genetics of acute myeloid leukaemia. Best Practice & Research Clinical Haematology 14:1, pages 49-64.
Crossref
Crossref
HN Crans & KM Sakamoto. (2001) Transcription factors and translocations in lymphoid and myeloid leukemia. Leukemia 15:3, pages 313-331.
Crossref
Crossref
Thomas Pabst, Beatrice U. Mueller, Pu Zhang, Hanna S. Radomska, Sailaja Narravula, Susanne Schnittger, Gerhard Behre, Wolfgang Hiddemann & Daniel G. Tenen. (2001) Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia. Nature Genetics 27:3, pages 263-270.
Crossref
Crossref
Dong-Er Zhang, Sebastien Burel, Liming Zhou, Christopher J. Hetherington & Youzhong Yuan. (2001) AML1 and AML1 Fusion Protein AML1-ETO in Myeloid Gene Regulation and Leukemogenesis. Blood Cells, Molecules, and Diseases 27:2, pages 368-376.
Crossref
Crossref
Jochen Hess, Dominique Porte, Christine Munz & Peter Angel. (2001) AP-1 and Cbfa/Runt Physically Interact and Regulate Parathyroid Hormone-dependent MMP13 Expression in Osteoblasts through a New Osteoblast-specific Element 2/AP-1 Composite Element. Journal of Biological Chemistry 276:23, pages 20029-20038.
Crossref
Crossref
Mario Faretta, Luciano Di Croce & Pier Giuseppe Pelicci. (2001) Effects of the acute myeloid leukemia-associated fusion proteins on nuclear architecture. Seminars in Hematology 38:1, pages 42-53.
Crossref
Crossref
Ari MelnickGraeme W. CarlileMelanie J. McConnellAdam PolingerScott W. HiebertJonathan D. Licht. (2000) AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein. Blood 96:12, pages 3939-3947.
Crossref
Crossref
Ari MelnickGraeme W. CarlileMelanie J. McConnellAdam PolingerScott W. HiebertJonathan D. Licht. (2000) AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein. Blood 96:12, pages 3939-3947.
Crossref
Crossref
K. I. Mills. (2000) Differential display as an approach to study differentiation and differentiation therapy in AML. Hematological Oncology 18:4, pages 129-140.
Crossref
Crossref
Colette Adida, Christian Recher, Emmanuel Raffoux, Marie-Thérèse Daniel, Anne-Laure Taksin, Philippe Rousselot, François Sigaux, Laurent Degos, Dario C. Altieri & Hervé Dombret. (2000)
Expression and prognostic significance of survivin in
de novo
acute myeloid leukaemia
. British Journal of Haematology 111:1, pages 196-203.
Crossref
Crossref
Colette Adida, Christian Recher, Emmanuel Raffoux, Marie-Therese Daniel, Anne-Laure Taksin, Philippe Rousselot, Francois Sigaux, Laurent Degos, Dario C. Altieri & Herve Dombret. (2000) Expression and prognostic significance of survivin in de novo acute myeloid leukaemia. British Journal of Haematology 111:1, pages 196-203.
Crossref
Crossref
James R Downing, Masakazu Higuchi, Noel Lenny & Allen Eng-Juh Yeoh. (2000) Alterations of the AML1 transcription factor in human leukemia. Seminars in Cell & Developmental Biology 11:5, pages 347-360.
Crossref
Crossref
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