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DNA Dynamics and Chromosome Structure

Lagging-Strand, Early-Labelling, and Two-Dimensional Gel Assays Suggest Multiple Potential Initiation Sites in the Chinese Hamster Dihydrofolate Reductase Origin

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Pages 39-50 | Received 23 Apr 1997, Accepted 02 Oct 1997, Published online: 28 Mar 2023

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Michelle Malott & Michael Leffak. (1999) Activity of the c-myc Replicator at an Ectopic Chromosomal Location. Molecular and Cellular Biology 19:8, pages 5685-5695.
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Gérard Pierron, Dominick Pallotta & Marianne Bénard. (1999) The One-Kilobase DNA Fragment Upstream of the ardC Actin Gene of Physarum polycephalum Is Both a Replicator and a Promoter. Molecular and Cellular Biology 19:5, pages 3506-3514.
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Takehiko Kobayashi, Theo Rein & Melvin L. DePamphilis. (1998) Identification of Primary Initiation Sites for DNA Replication in the Hamster Dihydrofolate Reductase Gene Initiation Zone. Molecular and Cellular Biology 18:6, pages 3266-3277.
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Articles from other publishers (27)

Nataliya Petryk, Malik Kahli, Yves d'Aubenton-Carafa, Yan Jaszczyszyn, Yimin Shen, Maud Silvain, Claude Thermes, Chun-Long Chen & Olivier Hyrien. (2016) Replication landscape of the human genome. Nature Communications 7:1.
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Christelle Cayrou, Benoit Ballester, Isabelle Peiffer, Romain Fenouil, Philippe Coulombe, Jean-Christophe Andrau, Jacques van Helden & Marcel Méchali. (2015) The chromatin environment shapes DNA replication origin organization and defines origin classes. Genome Research 25:12, pages 1873-1885.
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Olivier Hyrien. (2015) Peaks cloaked in the mist: The landscape of mammalian replication origins. Journal of Cell Biology 208:2, pages 147-160.
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Yoav Lubelsky, Takayo Sasaki, Marjorie A. Kuipers, Isabelle Lucas, Michelle M. Le Beau, Sandra Carignon, Michelle Debatisse, Joseph A. Prinz, Jonathan H. Dennis & David M. Gilbert. (2011) Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone. Nucleic Acids Research 39:8, pages 3141-3155.
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Chrystelle Maric, Marianne Bénard & Gérard Pierron. (2010) RNase-dependent discontinuities associated with the crossovers of spontaneously formed joint DNA molecules in Physarum polycephalum. Chromosoma 119:6, pages 601-611.
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Joyce L. Hamlin, Larry D. Mesner & Pieter A. Dijkwel. (2009) A winding road to origin discovery. Chromosome Research 18:1, pages 45-61.
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H.-B. Lin, P.A. Dijkwel & J.L. Hamlin. (2005) Promiscuous initiation on mammalian chromosomal DNA templates and its possible suppression by transcription. Experimental Cell Research 308:1, pages 53-64.
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Larry D. Mesner & Joyce L. Hamlin. (2005) Specific signals at the 3′ end of the DHFR gene define one boundary of the downstream origin of replication . Genes & Development 19:9, pages 1053-1066.
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Hisao Masai, Zhiying You & Ken-ichi Arai. (2005) Control of DNA Replication: Regulation and Activation of Eukaryotic Replicative Helicase, MCM. IUBMB Life (International Union of Biochemistry and Molecular Biology: Life) 57:4-5, pages 323-335.
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Wenge Zhu, Tarek Abbas & Anindya Dutta. 2005. Genome Instability in Cancer Development. Genome Instability in Cancer Development 249 279 .
Swati Saha, Yujie Shan, Larry D. Mesner & Joyce L. Hamlin. (2004) The promoter of the Chinese hamster ovary dihydrofolate reductase gene regulates the activity of the local origin and helps define its boundaries. Genes & Development 18:4, pages 397-410.
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T I Kuschak, B C Kuschak, C L Taylor, J A Wright, F Wiener & S Mai. (2002) c-Myc initiates illegitimate replication of the ribonucleotide reductase R2 gene. Oncogene 21:6, pages 909-920.
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Marcel Méchali. (2001) DNA replication origins: from sequence specificity to epigenetics. Nature Reviews Genetics 2:8, pages 640-645.
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Lucy Lu, Hongjun Zhang & John Tower. (2001) Functionally distinct, sequence-specific replicator and origin elements are required for Drosophila chorion gene amplification . Genes & Development 15:2, pages 134-146.
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P.A. Dijkwel, L.D. Mesner, V.V. Levenson, J. d'Anna & J.L. Hamlin. (2000) Dispersive Initiation of Replication in the Chinese Hamster Rhodopsin Locus. Experimental Cell Research 256:1, pages 150-157.
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Steven Henikoff. (2000) Heterochromatin function in complex genomes. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1470:1, pages O1-O8.
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Stefano Rivella, Belinda Palermo, Cristina Pelizon, Cinzia Sala, Giulia Arrigo & Daniela Toniolo. (1999) Selection and Mapping of Replication Origins from a 500-kb Region of the Human X Chromosome and Their Relationship to Gene Expression. Genomics 62:1, pages 11-20.
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Daniela S. Dimitrova, Ivan T. Todorov, Thomas Melendy & David M. Gilbert. (1999) Mcm2, but Not Rpa, Is a Component of the Mammalian Early G1-Phase Prereplication Complex. Journal of Cell Biology 146:4, pages 709-722.
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Pieter A. Dijkwel & Joyce L. Hamlin. (1999) Physical and Genetic Mapping of Mammalian Replication Origins. Methods 18:3, pages 418-431.
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Simi T. Hurst & David H. Rivier. (1999) Identification of a Compound Origin of Replication at theHMR-E Locus in Saccharomyces cerevisiae. Journal of Biological Chemistry 274:7, pages 4155-4159.
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Anne D Donaldson & J Julian Blow. (1999) The regulation of replication origin activation. Current Opinion in Genetics & Development 9:1, pages 62-68.
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M. Benard & G. Pierron. (1999) Early activated replication origins within the cell cycle-regulated histone H4 genes in Physarum. Nucleic Acids Research 27:10, pages 2091-2098.
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Zhong Hui Wang & Ann M Fallon. (1999) Early-replicating DNA from mosquito cells is associated with a distinct EcoRI fragment. Insect Biochemistry and Molecular Biology 29:1, pages 53-61.
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Maria Zannis-Hadjopoulos & Gerald B. Price. (1999) Eukaryotic DNA replication. Journal of Cellular Biochemistry 75:S32, pages 1-14.
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R.F Kalejta, X Li, L.D Mesner, P.A Dijkwel, H.-B Lin & J.L Hamlin. (1998) Distal Sequences, but Not ori-β/OBR-1, Are Essential for Initiation of DNA Replication in the Chinese Hamster DHFR Origin. Molecular Cell 2:6, pages 797-806.
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D.S. DimitrovaD.M. Gilbert. (1998) Regulation of mammalian replication origin usage in Xenopus egg extract. Journal of Cell Science 111:19, pages 2989-2998.
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Loc Phi-van, Claudia Sellke, Alexandra von Bodenhausen & Wolf H. Strätling. (1998) An Initiation Zone of Chromosomal DNA Replication at the Chicken Lysozyme Gene Locus. Journal of Biological Chemistry 273:29, pages 18300-18307.
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