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Molecular and Cellular Biology Volume 18, 1998 - Issue 10
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Gene Expression

Processivity of the Saccharomyces cerevisiae Poly(A) Polymerase Requires Interactions at the Carboxyl-Terminal RNA Binding Domain

Alexander Zhelkovskya Department of Molecular Biology and Microbiology
,
Steffen Helmlingb Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts02111-1800
&
Claire Moorea Department of Molecular Biology and Microbiology;b Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts02111-1800Correspondence[email protected]
Pages 5942-5951 | Received 09 Jun 1998, Accepted 10 Jul 1998, Published online: 28 Mar 2023

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David A. Mangus, Matthew C. Evans, Nathan S. Agrin, Mandy Smith, Preetam Gongidi & Allan Jacobson. (2004) Positive and Negative Regulation of Poly(A) Nuclease. Molecular and Cellular Biology 24:12, pages 5521-5533.
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David A. Mangus, Mandy M. Smith, Jennifer M. McSweeney & Allan Jacobson. (2004) Identification of Factors Regulating Poly(A) Tail Synthesis and Maturation. Molecular and Cellular Biology 24:10, pages 4196-4206.
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Stefan Gross & Claire L. Moore. (2001) Rna15 Interaction with the A-Rich Yeast Polyadenylation Signal Is an Essential Step in mRNA 3′-End Formation. Molecular and Cellular Biology 21:23, pages 8045-8055.
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Steffen Helmling, Alexander Zhelkovsky & Claire L. Moore. (2001) Fip1 Regulates the Activity of Poly(A) Polymerase through Multiple Interactions. Molecular and Cellular Biology 21:6, pages 2026-2037.
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Neptune Mizrahi & Claire Moore. (2000) Posttranslational Phosphorylation and Ubiquitination of the Saccharomyces cerevisiae Poly(A) Polymerase at the S/G2 Stage of the Cell Cycle. Molecular and Cellular Biology 20:8, pages 2794-2802.
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Jing Zhao, Marco Kessler, Steffen Helmling, J. Patrick O’Connor & Claire Moore. (1999) Pta1, a Component of Yeast CF II, Is Required for Both Cleavage and Poly(A) Addition of mRNA Precursor. Molecular and Cellular Biology 19:11, pages 7733-7740.
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Articles from other publishers (30)

Komal Soni, Anusree Sivadas, Attila Horvath, Nikolay Dobrev, Rippei Hayashi, Leo Kiss, Bernd Simon, Klemens Wild, Irmgard Sinning & Tamás Fischer. (2023) Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex. Nature Communications 14:1.
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Juan B. Rodríguez‐Molina & Matti Turtola. (2022) Birth of a poly(A) tail: mechanisms and control of mRNA polyadenylation . FEBS Open Bio.
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Matti Turtola, M. Cemre Manav, Ananthanarayanan Kumar, Agnieszka Tudek, Seweryn Mroczek, Paweł S. Krawczyk, Andrzej Dziembowski, Manfred Schmid, Lori A. Passmore, Ana Casañal & Torben Heick Jensen. (2021) Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae . Genes & Development 35:17-18, pages 1290-1303.
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Nadra Al-Husini, Scott Medler & Athar Ansari. (2020) Crosstalk of promoter and terminator during RNA polymerase II transcription cycle. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1863:12, pages 194657.
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Agnieszka Tudek, Marta Lloret-Llinares & Torben Heick Jensen. (2018) The multitasking polyA tail: nuclear RNA maturation, degradation and export. Philosophical Transactions of the Royal Society B: Biological Sciences 373:1762, pages 20180169.
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Jin Wang, Hongping Dong, Yok Hian Chionh, Megan E. McBee, Sasilada Sirirungruang, Richard P. Cunningham, Pei-Yong Shi & Peter C. Dedon. (2016) The role of sequence context, nucleotide pool balance and stress in 2′-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA. Nucleic Acids Research 44:18, pages 8962-8975.
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Chukwudi Ezeokonkwo, Mohamed A. Ghazy, Alexander Zhelkovsky, Pei-Chun Yeh & Claire Moore. (2012) Novel interactions at the essential N-terminus of poly(A) polymerase that could regulate poly(A) addition in Saccharomyces cerevisiae . FEBS Letters 586:8, pages 1173-1178.
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Lisa S. Chen, Lei Du-Cuny, Vasupradha Vethantham, David H. Hawke, James L. Manley, Shuxing Zhang & Varsha Gandhi. (2010) Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues. Biochemical Pharmacology 79:5, pages 669-677.
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Yong Sun Lee, Yoshiyuki Shibata, Ankit Malhotra & Anindya Dutta. (2009) A novel class of small RNAs: tRNA-derived RNA fragments (tRFs). Genes & Development 23:22, pages 2639-2649.
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Natalia Bercovich, Mariano J. Levin & Martin P. Vazquez. (2009) The FIP-1 like polyadenylation factor in trypanosomes and the structural basis for its interaction with CPSF30. Biochemical and Biophysical Research Communications 380:4, pages 850-855.
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Lisa S. Chen, William Plunkett & Varsha Gandhi. (2008) Polyadenylation inhibition by the triphosphates of deoxyadenosine analogues. Leukemia Research 32:10, pages 1573-1581.
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Georges Martin, Sylvie Doublié & Walter Keller. (2008) Determinants of substrate specificity in RNA-dependent nucleotidyl transferases. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1779:4, pages 206-216.
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Corey R. Mandel & Liang Tong. (2007) How to Get All “A”s in Polyadenylation. Structure 15:9, pages 1024-1026.
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Paul B. Balbo & Andrew Bohm. (2007) Mechanism of Poly(A) Polymerase: Structure of the Enzyme-MgATP-RNA Ternary Complex and Kinetic Analysis. Structure 15:9, pages 1117-1131.
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Isabelle Bougie & Martin Bisaillon. (2007) Characterization of the RNA binding energetics of theCandida albicans poly(A) polymerase. Yeast 24:5, pages 431-446.
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Audrey Perreault, Caroline Lemieux & François Bachand. (2007) Regulation of the Nuclear Poly(A)-binding Protein by Arginine Methylation in Fission Yeast. Journal of Biological Chemistry 282:10, pages 7552-7562.
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Paul B. Balbo, Joe Toth & Andrew Bohm. (2007) X-ray Crystallographic and Steady State Fluorescence Characterization of the Protein Dynamics of Yeast Polyadenylate Polymerase. Journal of Molecular Biology 366:5, pages 1401-1415.
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Kevin P. Forbes, Balasubrahmanyam Addepalli & Arthur G. Hunt. (2006) An Arabidopsis Fip1 Homolog Interacts with RNA and Provides Conceptual Links with a Number of Other Polyadenylation Factor Subunits. Journal of Biological Chemistry 281:1, pages 176-186.
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Xiaoyuan He & Claire Moore. (2005) Regulation of Yeast mRNA 3′ End Processing by Phosphorylation. Molecular Cell 19:5, pages 619-629.
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Lisa S. Chen & Terry L. Sheppard. (2004) Chain Termination and Inhibition of Saccharomyces cerevisiae Poly(A) Polymerase by C-8-modified ATP Analogs. Journal of Biological Chemistry 279:39, pages 40405-40411.
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GEORGES MARTIN & WALTER KELLER. (2004) Sequence motifs that distinguish ATP(CTP):tRNA nucleotidyl transferases from eubacterial poly(A) polymerases. RNA 10:6, pages 899-906.
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ALEXANDER ZHELKOVSKY, STEFFEN HELMLING, ANDREW BOHM & CLAIRE MOORE. (2004) Mutations in the middle domain of yeast poly(A) polymerase affect interactions with RNA but not ATP. RNA 10:4, pages 558-564.
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Jae Eun Kwak, Liaoteng Wang, Scott Ballantyne, Judith Kimble & Marvin Wickens. (2004) Mammalian GLD-2 homologs are poly(A) polymerases. Proceedings of the National Academy of Sciences 101:13, pages 4407-4412.
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Mary Edmonds. 2002. 285 389 .
Stefan Gross & Claire Moore. (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I . Proceedings of the National Academy of Sciences 98:11, pages 6080-6085.
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M. I. Zarudnaya. (2001) mRNA polyadenylation. 2. Formation of poly(A) tails in yeast, plant, prokaryote and virus mRNAs. Biopolymers and Cell 17:3, pages 185-202.
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Joel BardAlexander M. ZhelkovskySteffen HelmlingThomas N. EarnestClaire L. MooreAndrew Bohm. (2000) Structure of Yeast Poly(A) Polymerase Alone and in Complex with 3'-dATP. Science 289:5483, pages 1346-1349.
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Silvia M.L. Barabino, Martin Ohnacker & Walter Keller. (2000) Distinct roles of two Yth1p domains in 3′-end cleavage and polyadenylation of yeast pre-mRNAs. The EMBO Journal 19:14, pages 3778-3787.
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Jing Zhao, Linda Hyman & Claire Moore. (1999) Formation of mRNA 3′ Ends in Eukaryotes: Mechanism, Regulation, and Interrelationships with Other Steps in mRNA Synthesis. Microbiology and Molecular Biology Reviews 63:2, pages 405-445.
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E Wahle. (1999) 3′-End processing of pre-mRNA in eukaryotes. FEMS Microbiology Reviews 23:3, pages 277-295.
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