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Transcriptional Regulation

ETO, a Target of t(8;21) in Acute Leukemia, Interacts with the N-CoR and mSin3 Corepressors

, , , , , , , , , , , & show all
Pages 7176-7184 | Received 16 Jul 1998, Accepted 27 Aug 1998, Published online: 28 Mar 2023

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Hong Nguyen, Jolene Mariotti, Diana Bareyan, Robert H Carnahan, Tracy Cooper, Christopher S Williams & Michael E Engel. (2015) Anti-MTG16 antibodies reveal MTG16 subcellular distribution and nucleocytoplasmic transport in erythroleukemia cells. Antibody Technology Journal 5, pages 27-41.
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Chun Guo, Qiande Hu, Chunxia Yan & Jinsong Zhang. (2009) Multivalent Binding of the ETO Corepressor to E Proteins Facilitates Dual Repression Controls Targeting Chromatin and the Basal Transcription Machinery. Molecular and Cellular Biology 29:10, pages 2644-2657.
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Brenda J. Chyla, Isabel Moreno-Miralles, Melissa A. Steapleton, Mary Ann Thompson, Srividya Bhaskara, Michael Engel & Scott W. Hiebert. (2008) Deletion of Mtg16, a Target of t(16;21), Alters Hematopoietic Progenitor Cell Proliferation and Lineage Allocation. Molecular and Cellular Biology 28:20, pages 6234-6247.
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Daniela Salat, Robert Liefke, Jörg Wiedenmann, Tilman Borggrefe & Franz Oswald. (2008) ETO, but Not Leukemogenic Fusion Protein AML1/ETO, Augments RBP-Jκ/SHARP-Mediated Repression of Notch Target Genes. Molecular and Cellular Biology 28:10, pages 3502-3512.
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Amy C. Moore, Joseph M. Amann, Christopher S. Williams, Emilios Tahinci, Tiffany E. Farmer, J. Andres Martinez, Genyan Yang, K. Scott Luce, Ethan Lee & Scott W. Hiebert. (2008) Myeloid Translocation Gene Family Members Associate with T-Cell Factors (TCFs) and Influence TCF-Dependent Transcription. Molecular and Cellular Biology 28:3, pages 977-987.
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Si-Xuan Qian, Jian-yong Li, Min Hong, Hai-Rong Qiu, Lei Fan & Wei Xu. (2008) Acute myeloid leukemia in four patients with t(8;21) treated with all-trans retinoic acid as a single agent. Leukemia & Lymphoma 49:5, pages 998-1001.
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Lotfy A. Mahmoud, Sameh S.A. Shamaa, Mohammad A. Salem, Doaa A. Aladle & Enas F.A. Goda. (2006) A study for evaluation of different diagnostic approaches in acute leukemia in Egypt. Hematology 11:2, pages 87-95.
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Joseph M. Amann, Brenda J. Irvin Chyla, Tiffany C. Ellis, Andres Martinez, Amy C. Moore, Jeffrey L. Franklin, Laura McGhee, Shari Meyers, Joyce E. Ohm, K. Scott Luce, Andre J. Ouelette, M. Kay Washington, Mary Ann Thompson, Dana King, Shiva Gautam, Robert J. Coffey, Robert H. Whitehead & Scott W. Hiebert. (2005) Mtgr1 Is a Transcriptional Corepressor That Is Required for Maintenance of the Secretory Cell Lineage in the Small Intestine. Molecular and Cellular Biology 25:21, pages 9576-9585.
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Francesco Piazza & Gianpietro Semenzato. (2004) Molecular therapeutic approaches to acute myeloid leukemia: targeting aberrant chromatin dynamics and signal transduction. Expert Review of Anticancer Therapy 4:3, pages 387-400.
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Kristie L. Durst, Bart Lutterbach, Tanawan Kummalue, Alan D. Friedman & Scott W. Hiebert. (2003) The inv(16) Fusion Protein Associates with Corepressors via a Smooth Muscle Myosin Heavy-Chain Domain. Molecular and Cellular Biology 23:2, pages 607-619.
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Joëlle Michaud, Hamish S. Scott & Robert Escher. (2003) AML1 Interconnected Pathways of Leukemogenesis. Cancer Investigation 21:1, pages 105-136.
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Cristina G. de Guzman, Alan J. Warren, Zheng Zhang, Larry Gartland, Paul Erickson, Harry Drabkin, Scott W. Hiebert & Christopher A. Klug. (2002) Hematopoietic Stem Cell Expansion and Distinct Myeloid Developmental Abnormalities in a Murine Model of the AML1-ETO Translocation. Molecular and Cellular Biology 22:15, pages 5506-5517.
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Joseph M. Amann, John Nip, David K. Strom, Bart Lutterbach, Hironori Harada, Noel Lenny, James R. Downing, Shari Meyers & Scott W. Hiebert. (2001) ETO, a Target of t(8;21) in Acute Leukemia, Makes Distinct Contacts with Multiple Histone Deacetylases and Binds mSin3A through Its Oligomerization Domain. Molecular and Cellular Biology 21:19, pages 6470-6483.
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Franco Calabi, Richard Pannell & Gordana Pavloska. (2001) Gene Targeting Reveals a Crucial Role forMTG8 in the Gut. Molecular and Cellular Biology 21:16, pages 5658-5666.
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Sebastien A. Burel, Nari Harakawa, Liming Zhou, Thomas Pabst, Daniel G. Tenen & Dong-Er Zhang. (2001) Dichotomy of AML1-ETO Functions: Growth Arrest versus Block of Differentiation. Molecular and Cellular Biology 21:16, pages 5577-5590.
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Mukul Mathur, Philip W. Tucker & Herbert H. Samuels. (2001) PSF Is a Novel Corepressor That Mediates Its Effect through Sin3A and the DNA Binding Domain of Nuclear Hormone Receptors. Molecular and Cellular Biology 21:7, pages 2298-2311.
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V. Sontini, A. Gozzini, B. Scappini, A. Grossi & P. Rossi Ferrini. (2001) Searching for the Magic Bullet Against Cancer: The Butyrate Saga. Leukemia & Lymphoma 42:3, pages 275-289.
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Tokiko Nagamura-Inoue, Tomohiko Tamura & Keiko Ozato. (2001) Transcription Factors that Regulate Growth and Differentiation of Myeloid Cells. International Reviews of Immunology 20:1, pages 83-105.
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Jinsong Zhang, Bruce A. Hug, Eric Y. Huang, Clarice W. Chen, Vania Gelmetti, Marco Maccarana, Saverio Minucci, Pier Giuseppe Pelicci & Mitchell A. Lazar. (2001) Oligomerization of ETO Is Obligatory for Corepressor Interaction. Molecular and Cellular Biology 21:1, pages 156-163.
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Randy Fenrick, Lilin Wang, John Nip, Joseph M. Amann, Robert J. Rooney, Jennifer Walker-Daniels, Howard C. Crawford, Diana L. Hulboy, Michael S. Kinch, Lynn M. Matrisian & Scott W. Hiebert. (2000) TEL, a Putative Tumor Suppressor, Modulates Cell Growth and Cell Morphology of Ras-Transformed Cells While Repressing the Transcription of stromelysin-1. Molecular and Cellular Biology 20:16, pages 5828-5839.
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Suming Huang & Stephen J. Brandt. (2000) mSin3A Regulates Murine Erythroleukemia Cell Differentiation through Association with the TAL1 (or SCL) Transcription Factor. Molecular and Cellular Biology 20:6, pages 2248-2259.
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Ari M. Melnick, Jennifer J. Westendorf, Adam Polinger, Graeme W. Carlile, Sally Arai, Helen J. Ball, Bart Lutterbach, Scott W. Hiebert & Jonathan D. Licht. (2000) The ETO Protein Disrupted in t(8;21)-Associated Acute Myeloid Leukemia Is a Corepressor for the Promyelocytic Leukemia Zinc Finger Protein. Molecular and Cellular Biology 20:6, pages 2075-2086.
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Randy Fenrick, Joseph M. Amann, Bart Lutterbach, Lilin Wang, Jennifer J. Westendorf, James R. Downing & Scott W. Hiebert. (1999) Both TEL and AML-1 Contribute Repression Domains to the t(12;21) Fusion Protein. Molecular and Cellular Biology 19:10, pages 6566-6574.
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Jinsong Zhang, Xiao Hu & Mitchell A. Lazar. (1999) A Novel Role for Helix 12 of Retinoid X Receptor in Regulating Repression. Molecular and Cellular Biology 19:9, pages 6448-6457.
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Judith E Karp & Clarence B Sarkodee-Adoo. (1999) Acute progranulocytic leukaemia: a model for molecular medicine. Emerging Therapeutic Targets 3:1, pages 135-150.
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