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Gene Expression

Identification and Characterization of Pancreatic Eukaryotic Initiation Factor 2 α-Subunit Kinase, PEK, Involved in Translational Control

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Pages 7499-7509 | Received 27 Apr 1998, Accepted 06 Sep 1998, Published online: 28 Mar 2023

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Tomoko Kawai, Jinshui Fan, Krystyna Mazan-Mamczarz & Myriam Gorospe. (2004) Global mRNA Stabilization Preferentially Linked to Translational Repression during the Endoplasmic Reticulum Stress Response. Molecular and Cellular Biology 24:15, pages 6773-6787.
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Hao-Yuan Jiang, Sheree A. Wek, Barbara C. McGrath, Dan Lu, Tsonwin Hai, Heather P. Harding, Xiaozhong Wang, David Ron, Douglas R. Cavener & Ronald C. Wek. (2004) Activating Transcription Factor 3 Is Integral to the Eukaryotic Initiation Factor 2 Kinase Stress Response. Molecular and Cellular Biology 24:3, pages 1365-1377.
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Ann-Hwee Lee, Neal N. Iwakoshi & Laurie H. Glimcher. (2003) XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response. Molecular and Cellular Biology 23:21, pages 7448-7459.
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Sara B. Cullinan, Donna Zhang, Mark Hannink, Edward Arvisais, Randal J. Kaufman & J. Alan Diehl. (2003) Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival. Molecular and Cellular Biology 23:20, pages 7198-7209.
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Hao-Yuan Jiang, Sheree A. Wek, Barbara C. McGrath, Donalyn Scheuner, Randal J. Kaufman, Douglas R. Cavener & Ronald C. Wek. (2003) Phosphorylation of the α Subunit of Eukaryotic Initiation Factor 2 Is Required for Activation of NF-κB in Response to Diverse Cellular Stresses. Molecular and Cellular Biology 23:16, pages 5651-5663.
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Constantinos Koumenis, Christine Naczki, Marianne Koritzinsky, Sally Rastani, Alan Diehl, Nahum Sonenberg, Antonis Koromilas & Bradly G. Wouters. (2002) Regulation of Protein Synthesis by Hypoxia via Activation of the Endoplasmic Reticulum Kinase PERK and Phosphorylation of the Translation Initiation Factor eIF2α. Molecular and Cellular Biology 22:21, pages 7405-7416.
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Ke Zhan, Krishna M. Vattem, Bettina N. Bauer, Thomas E. Dever, Jane-Jane Chen & Ronald C. Wek. (2002) Phosphorylation of Eukaryotic Initiation Factor 2 by Heme-Regulated Inhibitor Kinase-Related Protein Kinases in Schizosaccharomyces pombe Is Important for Resistance to Environmental Stresses. Molecular and Cellular Biology 22:20, pages 7134-7146.
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Peichuan Zhang, Barbara McGrath, Sheng'ai Li, Ami Frank, Frank Zambito, Jamie Reinert, Maureen Gannon, Kun Ma, Kelly McNaughton & Douglas R. Cavener. (2002) The PERK Eukaryotic Initiation Factor 2α Kinase Is Required for the Development of the Skeletal System, Postnatal Growth, and the Function and Viability of the Pancreas. Molecular and Cellular Biology 22:11, pages 3864-3874.
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Linrong Lu, An-Ping Han & Jane-Jane Chen. (2001) Translation Initiation Control by Heme-Regulated Eukaryotic Initiation Factor 2α Kinase in Erythroid Cells under Cytoplasmic Stresses. Molecular and Cellular Biology 21:23, pages 7971-7980.
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Hiderou Yoshida, Tetsuya Okada, Kyosuke Haze, Hideki Yanagi, Takashi Yura, Manabu Negishi & Kazutoshi Mori. (2000) ATF6 Activated by Proteolysis Binds in the Presence of NF-Y (CBF) Directly to the cis-Acting Element Responsible for the Mammalian Unfolded Protein Response. Molecular and Cellular Biology 20:18, pages 6755-6767.
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Marion C. Bonnet, Robert Weil, Elisabeth Dam, Ara G. Hovanessian & Eliane F. Meurs. (2000) PKR Stimulates NF-κB Irrespective of Its Kinase Function by Interacting with the IκB Kinase Complex. Molecular and Cellular Biology 20:13, pages 4532-4542.
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Ruojing Yang, Sheree A. Wek & Ronald C. Wek. (2000) Glucose Limitation Induces GCN4 Translation by Activation of Gcn2 Protein Kinase. Molecular and Cellular Biology 20:8, pages 2706-2717.
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