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Gene Expression

The Pre-mRNA 5′ Cap Determines Whether U6 Small Nuclear RNA Succeeds U1 Small Nuclear Ribonucleoprotein Particle at 5′ Splice Sites

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Pages 7510-7520 | Received 04 Jun 1998, Accepted 31 Aug 1998, Published online: 28 Mar 2023

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Ian C. Eperon, Olga V. Makarova, Akila Mayeda, Stephen H. Munroe, Javier F. Cáceres, Daniel G. Hayward & Adrian R. Krainer. (2000) Selection of Alternative 5′ Splice Sites: Role of U1 snRNP and Models for the Antagonistic Effects of SF2/ASF and hnRNP A1. Molecular and Cellular Biology 20:22, pages 8303-8318.
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Articles from other publishers (28)

Hossein Shenasa & David L. Bentley. (2023) Pre-mRNA splicing and its cotranscriptional connections. Trends in Genetics.
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Alex Ranieri Jerônimo Lima, Herbert Guimarães de Sousa Silva, Saloe Poubel, Juliana Nunes Rosón, Loyze Paola Oliveira de Lima, Héllida Marina Costa-Silva, Camila Silva Gonçalves, Pedro A. F. Galante, Fabiola Holetz, Maria Cristina Machado Motta, Ariel M. Silber, M. Carolina Elias & Julia Pinheiro Chagas da Cunha. (2022) Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci. Epigenetics & Chromatin 15:1.
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Jean-Clement Mars, Mehdi Ghram, Biljana Culjkovic-Kraljacic & Katherine L. B. Borden. (2021) The Cap-Binding Complex CBC and the Eukaryotic Translation Factor eIF4E: Co-Conspirators in Cap-Dependent RNA Maturation and Translation. Cancers 13:24, pages 6185.
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Xavier Rambout & Lynne E. Maquat. (2020) The nuclear cap-binding complex as choreographer of gene transcription and pre-mRNA processing. Genes & Development 34:17-18, pages 1113-1127.
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Michael Tellier, Isabella Maudlin & Shona Murphy. (2020) Transcription and splicing: A two‐way street. WIREs RNA 11:5.
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Li Chen, Robert Weinmeister, Jana Kralovicova, Lucy P. Eperon, Igor Vorechovsky, Andrew J. Hudson & Ian C. Eperon. (2016) Stoichiometries of U2AF35, U2AF65 and U2 snRNP reveal new early spliceosome assembly pathways. Nucleic Acids Research, pages gkw860.
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Lindsay D. Smith, Rachel L. Dickinson, Christian M. Lucas, Alex Cousins, Alexey A. Malygin, Carika Weldon, Andrew J. Perrett, Andrew R. Bottrill, Mark S. Searle, Glenn A. Burley & Ian C. Eperon. (2014) A Targeted Oligonucleotide Enhancer of SMN2 Exon 7 Splicing Forms Competing Quadruplex and Protein Complexes in Functional Conditions. Cell Reports 9:1, pages 193-205.
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Rehab F. Abdelhamid, Charles Plessy, Yoshio Yamauchi, Masato Taoka, Michiel de Hoon, Thomas R. Gingeras, Toshiaki Isobe & Piero Carninci. (2014) Multiplicity of 5′ Cap Structures Present on Short RNAs. PLoS ONE 9:7, pages e102895.
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Yue-Bei Luo, Frank L Mastaglia & Steve D Wilton. (2014) Normal and aberrant splicing of LMNA . Journal of Medical Genetics 51:4, pages 215-223.
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Marta Pabis, Noa Neufeld, Michaela C. Steiner, Teodora Bojic, Yaron Shav-Tal & Karla M. Neugebauer. (2013) The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells. RNA 19:8, pages 1054-1063.
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Helen Lewis, Andrew J. Perrett, Glenn A. Burley & Ian C. Eperon. (2012) An RNA Splicing Enhancer that Does Not Act by Looping. Angewandte Chemie International Edition 51:39, pages 9800-9803.
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Helen Lewis, Andrew J. Perrett, Glenn A. Burley & Ian C. Eperon. (2012) An RNA Splicing Enhancer that Does Not Act by Looping. Angewandte Chemie 124:39, pages 9938-9941.
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Hagen Tilgner, David G. Knowles, Rory Johnson, Carrie A. Davis, Sudipto Chakrabortty, Sarah Djebali, João Curado, Michael Snyder, Thomas R. Gingeras & Roderic Guigó. (2012) Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs. Genome Research 22:9, pages 1616-1625.
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Mireia Bragulat, Markus Meyer, Sara Macías, Maria Camats, Mireia Labrador & Josep Vilardell. (2010) RPL30 regulation of splicing reveals distinct roles for Cbp80 in U1 and U2 snRNP cotranscriptional recruitment . RNA 16:10, pages 2033-2041.
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Nova Fong, Marie Öhman & David L Bentley. (2009) Fast ribozyme cleavage releases transcripts from RNA polymerase II and aborts co-transcriptional pre-mRNA processing. Nature Structural & Molecular Biology 16:9, pages 916-922.
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Munshi Azad Hossain, Julia M. Claggett, Tiffany Nguyen & Tracy L. Johnson. (2009) The cap binding complex influences H2B ubiquitination by facilitating splicing of the SUS1 pre-mRNA . RNA 15:8, pages 1515-1527.
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DL Ambrósio, MTA Silva & RMB Cicarelli. (2007) Cloning and molecular characterization of Trypanosoma cruzi U2, U4, U5, and U6 small nuclear RNAs. Memórias do Instituto Oswaldo Cruz 102:1, pages 97-106.
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Naglis Malys & John E.G. McCarthy. (2006) Dcs2, a Novel Stress-induced Modulator of m7GpppX Pyrophosphatase Activity that Locates to P Bodies. Journal of Molecular Biology 363:2, pages 370-382.
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Janina Görnemann, Kimberly M. Kotovic, Katja Hujer & Karla M. Neugebauer. (2005) Cotranscriptional Spliceosome Assembly Occurs in a Stepwise Fashion and Requires the Cap Binding Complex. Molecular Cell 19:1, pages 53-63.
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Joseph A. Bokar. 2005. Fine-Tuning of RNA Functions by Modification and Editing. Fine-Tuning of RNA Functions by Modification and Editing 141 177 .
Zhi-Ming Zheng. (2004) Regulation of alternative RNA splicing by exon definition and exon sequences in viral and mammalian gene expression. Journal of Biomedical Science 11:3, pages 278-294.
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Zhi-Ming Zheng, Mingfang Tao, Koji Yamanegi, Sohrab Bodaghi & Wei Xiao. (2004) Splicing of a Cap-proximal Human Papillomavirus 16 E6E7 Intron Promotes E7 Expression, but can be Restrained by Distance of the Intron from its RNA 5′ Cap. Journal of Molecular Biology 337:5, pages 1091-1108.
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Yuedi Wang & Mark T McNally. (2003) Position dependence of the rous sarcoma virus negative regulator of splicing element reflects proximity to a 5′ splice site. Virology 313:2, pages 629-637.
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Kevin Vincent, Qiang Wang, Steven Jay, Kathryn Hobbs & Brian C Rymond. (2003) Genetic Interactions With CLF1 Identify Additional Pre-mRNA Splicing Factors and a Link Between Activators of Yeast Vesicular Transport and Splicing . Genetics 164:3, pages 895-907.
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Zhi-Ming Zheng. (2003) Split genes and their expression in Kaposi's sarcoma-associated herpesvirus. Reviews in Medical Virology 13:3, pages 173-184.
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Kenneth James Howe. (2002) RNA polymerase II conducts a symphony of pre-mRNA processing activities. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1577:2, pages 308-324.
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Nick J. Proudfoot, Andre Furger & Michael J. Dye. (2002) Integrating mRNA Processing with Transcription. Cell 108:4, pages 501-512.
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Mikko J Frilander & Joan A Steitz. (2001) Dynamic Exchanges of RNA Interactions Leading to Catalytic Core Formation in the U12-Dependent Spliceosome. Molecular Cell 7:1, pages 217-226.
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