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Cell Growth and Development

Activation of Src Family Members Is Not Required for the Platelet-Derived Growth Factor β Receptor To Initiate Mitogenesis

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Pages 2014-2022 | Received 18 Sep 1997, Accepted 20 Jan 1998, Published online: 27 Mar 2023

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Rina Plattner, Anthony J. Koleske, Andrius Kazlauskas & Ann Marie Pendergast. (2004) Bidirectional Signaling Links the Abelson Kinases to the Platelet-Derived Growth Factor Receptor. Molecular and Cellular Biology 24:6, pages 2573-2583.
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Robert A. Blake, Martin A. Broome, Xiangdong Liu, Jianming Wu, Mikhail Gishizky, Li Sun & Sara A. Courtneidge. (2000) SU6656, a Selective Src Family Kinase Inhibitor, Used To Probe Growth Factor Signaling. Molecular and Cellular Biology 20:23, pages 9018-9027.
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Stephan Rosenkranz & Andrius Kazlauskas. (1999) Evidence for Distinct Signaling Properties and Biological Responses Induced by the PDGF Receptor α and β Subtypes. Growth Factors 16:3, pages 201-216.
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Zhitao Wang, Bangyao Sun, Qi Gao, Yong Ma, Yumeng Liang, Zhijie Chen, Hanguang Wu, Lu Cui, Yuhao Shao, Ping Wei, Hai Li & Shengwang Liu. (2019) Host Src controls gallid alpha herpesvirus 1 intercellular spread in a cellular fatty acid metabolism-dependent manner. Virology 537, pages 1-13.
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Wei-Rong Yang, Feng-Wei Zhu, Jiao-Jiao Zhang, Yi Wang, Jia-Hua Zhang, Cheng Lu & Xian-Zhong Wang. (2017) PI3K/Akt Activated by GPR30 and Src Regulates 17β-Estradiol-Induced Cultured Immature Boar Sertoli Cells Proliferation. Reproductive Sciences 24:1, pages 57-66.
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Jean-Baptiste Demoulin & Ahmed Essaghir. (2014) PDGF receptor signaling networks in normal and cancer cells. Cytokine & Growth Factor Reviews 25:3, pages 273-283.
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Michael J. Gray & Gary E. Gallick. 2010. Mechanisms of Oncogenesis. Mechanisms of Oncogenesis 19 41 .
Ramars Amanchy, Jun Zhong, Rosa Hong, James H. Kim, Marjan Gucek, Robert N. Cole, Henrik Molina & Akhilesh Pandey. (2009) Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling. Molecular Oncology 3:5-6, pages 439-450.
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Divyamani Srinivasan, David M. Kaetzel & Rina Plattner. (2009) Reciprocal regulation of Abl and receptor tyrosine kinases. Cellular Signalling 21:7, pages 1143-1150.
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Ruth Williams. (2008) Kris DeMali: Fixed on cell adhesion. Journal of Cell Biology 182:6, pages 1032-1033.
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Andrius Kazlauskas. 2008. Angiogenesis. Angiogenesis 99 111 .
Eunok Im & Andrius Kazlauskas. (2007) Src Family Kinases Promote Vessel Stability by Antagonizing the Rho/ROCK Pathway. Journal of Biological Chemistry 282:40, pages 29122-29129.
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Anna Platek, Vassil S. Vassilev, Philippe de Diesbach, Donatienne Tyteca, Marcel Mettlen & Pierre J. Courtoy. (2007) Constitutive diffuse activation of phosphoinositide 3-kinase at the plasma membrane by v-Src suppresses the chemotactic response to PDGF by abrogating the polarity of PDGF receptor signalling. Experimental Cell Research 313:6, pages 1090-1105.
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Andree Blaukat. 2007. xPharm: The Comprehensive Pharmacology Reference. xPharm: The Comprehensive Pharmacology Reference 1 14 .
Goutam Ghosh Choudhury, Lenin Mahimainathan, Falguni Das, Balachandar Venkatesan & Nandini Ghosh-Choudhury. (2006) c-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cells. Cellular Signalling 18:11, pages 1854-1864.
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Ricardo H. Alvarez, Hagop M. Kantarjian & Jorge E. Cortes. (2006) The role of Src in solid and hematologic malignancies. Cancer 107:8, pages 1918-1929.
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Laurence Veracini, Mélanie Franco, Anthony Boureux, Valérie Simon, Serge Roche & Christine Benistant. (2006) Two distinct pools of Src family tyrosine kinases regulate PDGF-induced DNA synthesis and actin dorsal ruffles. Journal of Cell Science 119:14, pages 2921-2934.
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Kavita Shah & Fabien Vincent. (2005) Divergent Roles of c-Src in Controlling Platelet-derived Growth Factor-dependent Signaling in Fibroblasts. Molecular Biology of the Cell 16:11, pages 5418-5432.
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Serena Catarzi, Chiara Biagioni, Elisa Giannoni, Fabio Favilli, Tommaso Marcucci, Teresa Iantomasi & Maria Teresa Vincenzini. (2005) Redox regulation of platelet-derived-growth-factor-receptor: Role of NADPH-oxidase and c-Src tyrosine kinase. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1745:2, pages 166-175.
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Christopher S. Newton, Elena Loukinova, Irina Mikhailenko, Sripriya Ranganathan, Yamei Gao, Christian Haudenschild & Dudley K. Strickland. (2005) Platelet-derived Growth Factor Receptor-β (PDGFR-β) Activation Promotes Its Association with the Low Density Lipoprotein Receptor-related Protein (LRP). Journal of Biological Chemistry 280:30, pages 27872-27878.
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Paul A Bromann, Hasan Korkaya & Sara A Courtneidge. (2004) The interplay between Src family kinases and receptor tyrosine kinases. Oncogene 23:48, pages 7957-7968.
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Si Qing Zhang, Wentian Yang, Maria I. Kontaridis, Trever G. Bivona, Gengyun Wen, Toshiyuki Araki, Jincai Luo, Julie A. Thompson, Burkhart L. Schraven, Mark R. Philips & Benjamin G. Neel. (2004) Shp2 Regulates Src Family Kinase Activity and Ras/Erk Activation by Controlling Csk Recruitment. Molecular Cell 13:3, pages 341-355.
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Rina Plattner, Brenda J. Irvin, Shuling Guo, Kevin Blackburn, Andrius Kazlauskas, Robert T. Abraham, John D. York & Ann Marie Pendergast. (2003) A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-γ1. Nature Cell Biology 5:4, pages 309-319.
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Bai Lin Tan, Li Hong, Veerendra Munugalavadla & Reuben Kapur. (2003) Functional and Biochemical Consequences of Abrogating the Activation of Multiple Diverse Early Signaling Pathways in Kit. Journal of Biological Chemistry 278:13, pages 11686-11695.
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Pablo M. Irusta, Yue Luo, Omar Bakht, Char-Chang Lai, Steven O. Smith & Daniel DiMaio. (2002) Definition of an Inhibitory Juxtamembrane WW-like Domain in the Platelet-derived Growth Factor β Receptor. Journal of Biological Chemistry 277:41, pages 38627-38634.
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Lisa F. Newcomb & Cynthia Corley Mastick. (2002) Src Family Kinase-Dependent Phosphorylation of a 29-kDa Caveolin-Associated Protein. Biochemical and Biophysical Research Communications 290:5, pages 1447-1453.
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H. E. Abboud. 2002. Encyclopedia of Molecular Biology. Encyclopedia of Molecular Biology.
Steven M. Jones & Andrius Kazlauskas. (2001) Growth Factor-Dependent Signaling and Cell Cycle Progression. Chemical Reviews 101:8, pages 2413-2424.
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Mark E. Nickas, Amy Bernard & Andrius Kazlauskas. (2001) The Requirement of Tyrosines 579 and 581 for Maximal Ligand-Dependent Activation of the βPDGFR Is Influenced by Noncytoplasmic Regions of the Receptor. Experimental Cell Research 265:1, pages 80-89.
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Steven M Jones & Andrius Kazlauskas. (2000) Connecting signaling and cell cycle progression in growth factor-stimulated cells. Oncogene 19:49, pages 5558-5567.
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Yi-Zhe Wang, Walker Wharton, Roy Garcia, Alan Kraker, Richard Jove & W J Pledger. (2000) Activation of Stat3 preassembled with platelet-derived growth factor β receptors requires Src kinase activity. Oncogene 19:17, pages 2075-2085.
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Char-Chang Lai, Carl Henningson & Daniel DiMaio. (2000) Bovine Papillomavirus E5 Protein Induces the Formation of Signal Transduction Complexes Containing Dimeric Activated Platelet-derived Growth Factor β Receptor and Associated Signaling Proteins. Journal of Biological Chemistry 275:13, pages 9832-9840.
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Stephan Rosenkranz, Yasushi Ikuno, Fee Lai Leong, Richard A. Klinghoffer, Sachiko Miyake, Hamid Band & Andrius Kazlauskas. (2000) Src Family Kinases Negatively Regulate Platelet-derived Growth Factor α Receptor-dependent Signaling and Disease Progression. Journal of Biological Chemistry 275:13, pages 9620-9627.
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Malú G. Tansey, Robert H. Baloh, Jeffrey Milbrandt & Eugene M. JohnsonJr.Jr.. (2000) GFRα-Mediated Localization of RET to Lipid Rafts Is Required for Effective Downstream Signaling, Differentiation, and Neuronal Survival. Neuron 25:3, pages 611-623.
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Clare L. Abram & Sara A. Courtneidge. (2000) Src Family Tyrosine Kinases and Growth Factor Signaling. Experimental Cell Research 254:1, pages 1-13.
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Kris A. DeMali, Stephen L. Godwin, Stephen P. Soltoff & Andrius Kazlauskas. (1999) Multiple Roles for Src in a PDGF-Stimulated Cell. Experimental Cell Research 253:1, pages 271-279.
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Eduardo Perez Salazar & Enrique Rozengurt. (1999) Bombesin and Platelet-derived Growth Factor Induce Association of Endogenous Focal Adhesion Kinase with Src in Intact Swiss 3T3 Cells. Journal of Biological Chemistry 274:40, pages 28371-28378.
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Stephan Rosenkranz, Kris A. DeMali, Julie A. Gelderloos, Chantal Bazenet & Andrius Kazlauskas. (1999) Identification of the Receptor-associated Signaling Enzymes That Are Required for Platelet-derived Growth Factor-AA-dependent Chemotaxis and DNA Synthesis. Journal of Biological Chemistry 274:40, pages 28335-28343.
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Ana Olivera, Lisa Edsall, Samantha Poulton, Andrius Kazlauskas & Sarah Spiegel. (1999) Platelet‐derived growth factor‐induced activation of sphingosine kinase requires phosphorylation of the PDGF receptor tyrosine residue responsible for binding of PLCγ. The FASEB Journal 13:12, pages 1593-1600.
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Kris A. DeMali, Egle Balciunaite & Andrius Kazlauskas. (1999) Integrins Enhance Platelet-derived Growth Factor (PDGF)-dependent Responses by Altering the Signal Relay Enzymes That Are Recruited to the PDGF β Receptor. Journal of Biological Chemistry 274:28, pages 19551-19558.
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Christoph Sachsenmaier, Henry B Sadowski & Jonathan A Cooper. (1999) STAT activation by the PDGF receptor requires juxtamembrane phosphorylation sites but not Src tyrosine kinase activation. Oncogene 18:24, pages 3583-3592.
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Steven M. Jones, Richard Klinghoffer, Glenn D. Prestwich, Alex Toker & Andrius Kazlauskas. (1999) PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1. Current Biology 9:10, pages 512-521.
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Nader Rahimi, Wesley Hung, Eric Tremblay, Ron Saulnier & Bruce Elliott. (1998) c-Src Kinase Activity Is Required for Hepatocyte Growth Factor-induced Motility and Anchorage-independent Growth of Mammary Carcinoma Cells. Journal of Biological Chemistry 273:50, pages 33714-33721.
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