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Cell Growth and Development

MEK Kinase 1, a Substrate for DEVD-Directed Caspases, Is Involved in Genotoxin-Induced Apoptosis

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Pages 2416-2429 | Received 30 Sep 1997, Accepted 06 Jan 1998, Published online: 27 Mar 2023

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Maofu Fu, Chenguang Wang, Jian Wang, Xueping Zhang, Toshiyuki Sakamaki, Y. G. Yeung, Chawnshang Chang, Torsten Hopp, Suzanne A. W. Fuqua, Ellis Jaffray, Ron T. Hay, Jorma J. Palvimo, Olli A. Jänne & Richard G. Pestell. (2002) Androgen Receptor Acetylation Governs trans Activation and MEKK1-Induced Apoptosis without Affecting In Vitro Sumoylation and trans-Repression Function. Molecular and Cellular Biology 22:10, pages 3373-3388.
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Paul Shapiro. (2002) Ras-MAP Kinase Signaling Pathways and Control of Cell Proliferation: Relevance to Cancer Therapy. Critical Reviews in Clinical Laboratory Sciences 39:4-5, pages 285-330.
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Jiang-Yan Yang & Christian Widmann. (2001) Antiapoptotic Signaling Generated by Caspase-Induced Cleavage of RasGAP. Molecular and Cellular Biology 21:16, pages 5346-5358.
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Surender Kharbanda, Pramod Pandey, Teruo Yamauchi, Shailender Kumar, Masao Kaneki, Vijay Kumar, Ajit Bharti, Zhi-Min Yuan, Louis Ghanem, Ajay Rana, Ralph Weichselbaum, Gary Johnson & Donald Kufe. (2000) Activation of MEK Kinase 1 by the c-Abl Protein Tyrosine Kinase in Response to DNA Damage. Molecular and Cellular Biology 20:14, pages 4979-4989.
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Spencer B. Gibson, Ryan Oyer, Aaron C. Spalding, Steven M. Anderson & Gary L. Johnson. (2000) Increased Expression of Death Receptors 4 and 5 Synergizes the Apoptosis Response to Combined Treatment with Etoposide and TRAIL. Molecular and Cellular Biology 20:1, pages 205-212.
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Rakesh K. Srivastava, Steven J. Sollott, Leila Khan, Richard Hansford, Edward G. Lakatta & Dan L. Longo. (1999) Bcl-2 and Bcl-XL Block Thapsigargin-Induced Nitric Oxide Generation, c-Jun NH2-Terminal Kinase Activity, and Apoptosis. Molecular and Cellular Biology 19:8, pages 5659-5674.
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Nabil Ben Messaoud, Ilina Katzarova & José M. López. (2015) Basic Properties of the p38 Signaling Pathway in Response to Hyperosmotic Shock. PLOS ONE 10:9, pages e0135249.
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T Suddason & E Gallagher. (2015) A RING to rule them all? Insights into the Map3k1 PHD motif provide a new mechanistic understanding into the diverse roles of Map3k1. Cell Death & Differentiation 22:4, pages 540-548.
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Laiqun Zhang, Martin R. Dittmer, Ken Blackwell, Lauren M. Workman, Bruce Hostager & Hasem Habelhah. (2015) TRAIL activates JNK and NF-κB through RIP1-dependent and -independent pathways. Cellular Signalling 27:2, pages 306-314.
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Dylan M. Glubb, Mel J. Maranian, Kyriaki Michailidou, Karen A. Pooley, Kerstin B. Meyer, Siddhartha Kar, Saskia Carlebur, Martin O’Reilly, Joshua A. Betts, Kristine M. Hillman, Susanne Kaufmann, Jonathan Beesley, Sander Canisius, John L. Hopper, Melissa C. Southey, Helen Tsimiklis, Carmel Apicella, Marjanka K. Schmidt, Annegien Broeks, Frans B. Hogervorst, C. Ellen van der Schoot, Kenneth Muir, Artitaya Lophatananon, Sarah Stewart-Brown, Pornthep Siriwanarangsan, Peter A. Fasching, Matthias Ruebner, Arif B. Ekici, Matthias W. Beckmann, Julian Peto, Isabel dos-Santos-Silva, Olivia Fletcher, Nichola Johnson, Paul D.P. Pharoah, Manjeet K. Bolla, Qin Wang, Joe Dennis, Elinor J. Sawyer, Ian Tomlinson, Michael J. Kerin, Nicola Miller, Barbara Burwinkel, Frederik Marme, Rongxi Yang, Harald Surowy, Pascal Guénel, Thérèse Truong, Florence Menegaux, Marie Sanchez, Stig E. Bojesen, Børge G. Nordestgaard, Sune F. Nielsen, Henrik Flyger, Anna González-Neira, Javier Benitez, M. Pilar Zamora, Jose Ignacio Arias Perez, Hoda Anton-Culver, Susan L. Neuhausen, Hermann Brenner, Aida Karina Dieffenbach, Volker Arndt, Christa Stegmaier, Alfons Meindl, Rita K. Schmutzler, Hiltrud Brauch, Yon-Dschun Ko, Thomas Brüning, Heli Nevanlinna, Taru A. Muranen, Kristiina Aittomäki, Carl Blomqvist, Keitaro Matsuo, Hidemi Ito, Hiroji Iwata, Hideo Tanaka, Thilo Dörk, Natalia V. Bogdanova, Sonja Helbig, Annika Lindblom, Sara Margolin, Arto Mannermaa, Vesa Kataja, Veli-Matti Kosma, Jaana M. Hartikainen, Anna H. Wu, Chiu-chen Tseng, David Van Den Berg, Daniel O. Stram, Diether Lambrechts, Hui Zhao, Caroline Weltens, Erik van Limbergen, Jenny Chang-Claude, Dieter Flesch-Janys, Anja Rudolph, Petra Seibold, Paolo Radice, Paolo Peterlongo, Monica Barile, Fabio Capra, Fergus J. Couch, Janet E. Olson, Emily Hallberg, Celine Vachon, Graham G. Giles, Roger L. Milne, Catriona McLean, Christopher A. Haiman, Brian E. Henderson, Fredrick Schumacher, Loic Le Marchand, Jacques Simard, Mark S. Goldberg, France Labrèche, Martine Dumont, Soo Hwang Teo, Cheng Har Yip, Mee-Hoong See, Belinda Cornes, Ching-Yu Cheng, M. Kamran Ikram, Vessela Kristensen, Wei Zheng, Sandra L. Halverson, Martha Shrubsole, Jirong Long, Robert Winqvist, Katri Pylkäs, Arja Jukkola-Vuorinen, Saila Kauppila, Irene L. Andrulis, Julia A. Knight, Gord Glendon, Sandrine Tchatchou, Peter Devilee, Robert A.E.M. Tollenaar, Caroline Seynaeve, Christi J. Van Asperen, Montserrat García-Closas, Jonine Figueroa, Stephen J. Chanock, Jolanta Lissowska, Kamila Czene, Daniel Klevebring, Hatef Darabi, Mikael Eriksson, Maartje J. Hooning, Antoinette Hollestelle, John W.M. Martens, J. Margriet Collée, Per Hall, Jingmei Li, Keith Humphreys, Xiao-Ou Shu, Wei Lu, Yu-Tang Gao, Hui Cai, Angela Cox, Simon S. Cross, Malcolm W.R. Reed, William Blot, Lisa B. Signorello, Qiuyin Cai, Mitul Shah, Maya Ghoussaini, Daehee Kang, Ji-Yeob Choi, Sue K. Park, Dong-Young Noh, Mikael Hartman, Hui Miao, Wei Yen Lim, Anthony Tang, Ute Hamann, Diana Torres, Anna Jakubowska, Jan Lubinski, Katarzyna Jaworska, Katarzyna Durda, Suleeporn Sangrajrang, Valerie Gaborieau, Paul Brennan, James McKay, Curtis Olswold, Susan Slager, Amanda E. Toland, Drakoulis Yannoukakos, Chen-Yang Shen, Pei-Ei Wu, Jyh-Cherng Yu, Ming-Feng Hou, Anthony Swerdlow, Alan Ashworth, Nick Orr, Michael Jones, Guillermo Pita, M. Rosario Alonso, Nuria Álvarez, Daniel Herrero, Daniel C. Tessier, Daniel Vincent, Francois Bacot, Craig Luccarini, Caroline Baynes, Shahana Ahmed, Catherine S. Healey, Melissa A. Brown, Bruce A.J. Ponder, Georgia Chenevix-Trench, Deborah J. Thompson, Stacey L. Edwards, Douglas F. Easton, Alison M. Dunning & Juliet D. French. (2015) Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1. The American Journal of Human Genetics 96:1, pages 5-20.
Crossref
W Zeng, J Zhang, M Qi, C Peng, J Su, X Chen & Z Yuan. (2014) αNAC inhibition of the FADD-JNK axis plays anti-apoptotic role in multiple cancer cells. Cell Death & Disease 5:6, pages e1282-e1282.
Crossref
Chaitali Banerjee, Preeti Khatri, Rajagopal Raman, Himanshi Bhatia, Malabika Datta & Shibnath Mazumder. (2014) Role of Calmodulin-Calmodulin Kinase II, cAMP/Protein Kinase A and ERK 1/2 on Aeromonas hydrophila-Induced Apoptosis of Head Kidney Macrophages. PLoS Pathogens 10:4, pages e1004018.
Crossref
Teresa Palomero, Lucile Couronné, Hossein Khiabanian, Mi-Yeon Kim, Alberto Ambesi-Impiombato, Arianne Perez-Garcia, Zachary Carpenter, Francesco Abate, Maddalena Allegretta, J Erika Haydu, Xiaoyu Jiang, Izidore S Lossos, Concha Nicolas, Milagros Balbin, Christian Bastard, Govind Bhagat, Miguel A Piris, Elias Campo, Olivier A Bernard, Raul Rabadan & Adolfo A Ferrando. (2014) Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas. Nature Genetics 46:2, pages 166-170.
Crossref
Igseo Choi, Ronald O. Bates, Nancy E. Raney, Juan P. Steibel & Catherine W. Ernst. (2012) Evaluation of QTL for carcass merit and meat quality traits in a US commercial Duroc population. Meat Science 92:2, pages 132-138.
Crossref
Moon-Chang Choi, Todd J. Cohen, Tomasa Barrientos, Bin Wang, Ming Li, Bryan J. Simmons, Jeong Soo Yang, Gregory A. Cox, Yingming Zhao & Tso-Pang Yao. (2012) A Direct HDAC4-MAP Kinase Crosstalk Activates Muscle Atrophy Program. Molecular Cell 47:1, pages 122-132.
Crossref
Zhizhong Xu, Roshani Payoe & Richard P. Fahlman. (2012) The C-terminal Proteolytic Fragment of the Breast Cancer Susceptibility Type 1 Protein (BRCA1) Is Degraded by the N-end Rule Pathway. Journal of Biological Chemistry 287:10, pages 7495-7502.
Crossref
Yvonne M. Schichl, Ulrike Resch, Christof E. Lemberger, Dominik Stichlberger & Rainer de Martin. (2011) Novel Phosphorylation-dependent Ubiquitination of Tristetraprolin by Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase Kinase 1 (MEKK1) and Tumor Necrosis Factor Receptor-associated Factor 2 (TRAF2). Journal of Biological Chemistry 286:44, pages 38466-38477.
Crossref
Kohsuke TakedaIsao NaguroHideki NishitohAtsushi MatsuzawaHidenori Ichijo. (2011) Apoptosis Signaling Kinases: From Stress Response to Health Outcomes. Antioxidants & Redox Signaling 15:3, pages 719-761.
Crossref
Nick Warr, Debora Bogani, Pam Siggers, Rachel Brixey, Hilda Tateossian, Asha Dopplapudi, Sara Wells, Michael Cheeseman, Ying Xia, Harry Ostrer & Andy Greenfield. (2011) Minor Abnormalities of Testis Development in Mice Lacking the Gene Encoding the MAPK Signalling Component, MAP3K1. PLoS ONE 6:5, pages e19572.
Crossref
Mahesh Vaishnav, Marion MacFarlane & Martin Dickens. (2011) Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis. Experimental Cell Research 317:7, pages 1028-1039.
Crossref
Erin Tricker, Afsane Arvand, Raymond Kwan, Gordon Y. Chen, Ewen Gallagher & Genhong Cheng. (2011) Apoptosis Induced by Cytoskeletal Disruption Requires Distinct Domains of MEKK1. PLoS ONE 6:2, pages e17310.
Crossref
Sten Orrenius, Pierluigi Nicotera & Boris Zhivotovsky. (2011) Cell Death Mechanisms and Their Implications in Toxicology. Toxicological Sciences 119:1, pages 3-19.
Crossref
Ji-Hwan Hwang, Motoki Takagi, Hideki Murakami, Yoshitaka Sekido & Kazuo Shin-ya. (2011) Induction of tubulin polymerization and apoptosis in malignant mesothelioma cells by a new compound JBIR-23. Cancer Letters 300:2, pages 189-196.
Crossref
Ewen Gallagher. 2011. Advances in TNF Family Research. Advances in TNF Family Research 391 397 .
Ida Grotterød, Gunhild M Mælandsmo & Kjetil Boye. (2010) Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-κB. BMC Cancer 10:1.
Crossref
M. Rafiq Islam, Tamara Jimenez, Christopher Pelham, Marianna Rodova, Sanjeev Puri, Brenda S. Magenheimer, Robin L. Maser, Christian Widmann & James P. Calvet. (2010) MAP/ERK Kinase Kinase 1 (MEKK1) Mediates Transcriptional Repression by Interacting with Polycystic Kidney Disease-1 (PKD1) Promoter-bound p53 Tumor Suppressor Protein. Journal of Biological Chemistry 285:50, pages 38818-38831.
Crossref
Manabu Kurokawa & Sally Kornbluth. (2009) Caspases and Kinases in a Death Grip. Cell 138:5, pages 838-854.
Crossref
Pothana Saikumar & Manjeri A. Venkatachalam. 2009. Basic Concepts of Molecular Pathology. Basic Concepts of Molecular Pathology 29 40 .
Martin Ehrenschwender & Harald Wajant. 2009. Therapeutic Targets of the TNF Superfamily. Therapeutic Targets of the TNF Superfamily 64 93 .
D N Dhanasekaran & E P Reddy. (2008) JNK signaling in apoptosis. Oncogene 27:48, pages 6245-6251.
Crossref
Hanane Derradji, Sofie Bekaert, Tim De Meyer, Paul Jacquet, Khalil Abou-El-Ardat, Myriam Ghardi, Michaux Arlette & Sarah Baatout. (2008) Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects. Developmental Biology 322:2, pages 302-313.
Crossref
Kenneth M. Rassnick, Josephia R. Muindi, Candace S. Johnson, Cheryl E. Balkman, Nithya Ramnath, Wei-Dong Yu, Kristie L. Engler, Rodney L. Page & Donald L. Trump. (2008) In vitro and in vivo evaluation of combined calcitriol and cisplatin in dogs with spontaneously occurring tumors. Cancer Chemotherapy and Pharmacology 62:5, pages 881-891.
Crossref
Dariush Mokhtari, Jason W. Myers & Nils Welsh. (2008) MAPK Kinase Kinase-1 Is Essential for Cytokine-Induced c-Jun NH2-Terminal Kinase and Nuclear Factor-κB Activation in Human Pancreatic Islet Cells. Diabetes 57:7, pages 1896-1904.
Crossref
Yuwen He, Shaohui Cai, Ge Zhang, Xiaoqing Li, Liting Pan & Jun Du. (2008) Interfering with cellular signaling pathways enhances sensitization to combined sodium butyrate and GCV treatment in EBV-positive tumor cells. Virus Research 135:1, pages 175-180.
Crossref
Dariush Mokhtari, Jason W. Myers & Nils Welsh. (2008) The MAPK Kinase Kinase-1 Is Essential for Stress-Induced Pancreatic Islet Cell Death. Endocrinology 149:6, pages 3046-3053.
Crossref
Viktor Janzen, Heather E. Fleming, Tamara Riedt, Göran Karlsson, Matthew J. Riese, Cristina Lo Celso, Griffin Reynolds, Craig D. Milne, Christopher J. Paige, Stefan Karlsson, Minna Woo & David T. Scadden. (2008) Hematopoietic Stem Cell Responsiveness to Exogenous Signals Is Limited by Caspase-3. Cell Stem Cell 2:6, pages 584-594.
Crossref
Marina Vacotto, Omar Coso & Sara Fiszer de Plazas. (2008) Programmed cell death and differential JNK, p38 and ERK response in a prenatal acute hypoxic hypoxia model. Neurochemistry International 52:4-5, pages 857-863.
Crossref
A Nakajima, Y Kojima, M Nakayama, H Yagita, K Okumura & H Nakano. (2007) Downregulation of c-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells. Oncogene 27:1, pages 76-84.
Crossref
Aladin M. Boriek & Ashok Kumar. 2008. Mechanosensitive Ion Channels. Mechanosensitive Ion Channels 303 327 .
Janet V Cross, Frank W Foss, Joshua M Rady, Timothy L Macdonald & Dennis J Templeton. (2007) The isothiocyanate class of bioactive nutrients covalently inhibit the MEKK1 protein kinase. BMC Cancer 7:1.
Crossref
Bing Ye, Wei-ping Yu, Gareth M. Thomas & Richard L. Huganir. (2007) GRASP-1 is a neuronal scaffold protein for the JNK signaling pathway. FEBS Letters 581:23, pages 4403-4410.
Crossref
Normand Marceau, Bert Schutte, Stéphane Gilbert, Anne Loranger, Mieke E.R. Henfling, Jos L.V. Broers, Jasmin Mathew & Frans C.S. Ramaekers. (2007) Dual roles of intermediate filaments in apoptosis. Experimental Cell Research 313:10, pages 2265-2281.
Crossref
Yasuhisa Oida, Began Gopalan, Ryo Miyahara, Cynthia D. Branch, Paul Chiao, Sunil Chada & Rajagopal Ramesh. (2007) Inhibition of nuclear factor-κB augments antitumor activity of adenovirus-mediated melanoma differentiation-associated gene-7 against lung cancer cells via mitogen-activated protein kinase kinase kinase 1 activation. Molecular Cancer Therapeutics 6:4, pages 1440-1449.
Crossref
Jean da Silva Correia, Yvonne Miranda, Nikki Leonard & Richard J. Ulevitch. (2007) The Subunit CSN6 of the COP9 Signalosome Is Cleaved during Apoptosis. Journal of Biological Chemistry 282:17, pages 12557-12565.
Crossref
Pasan Fernando & Lynn A. Megeney. (2006) Is caspase‐dependent apoptosis only cell differentiation taken to the extreme?. The FASEB Journal 21:1, pages 8-17.
Crossref
Paul Dent, David T. Curiel & Paul B. Fisher. 2007. Apoptosis, Senescence, and Cancer. Apoptosis, Senescence, and Cancer 281 298 .
Go Fujino, Takuya Noguchi, Kohsuke Takeda & Hidenori Ichijo. (2006) Thioredoxin and protein kinases in redox signaling. Seminars in Cancer Biology 16:6, pages 427-435.
Crossref
Ruth Koren, Shiri Wacksberg, Gregory E. Weitsman & Amiram Ravid. (2006) Calcitriol sensitizes colon cancer cells to H2O2-induced cytotoxicity while inhibiting caspase activation. The Journal of Steroid Biochemistry and Molecular Biology 101:2-3, pages 151-160.
Crossref
Yun-Jung Kim, So-Young Hwang, Eok-Soo Oh, Seikwan Oh & Inn-Oc Han. (2006) IL-1β, an immediate early protein secreted by activated microglia, induces iNOS/NO in C6 astrocytoma cells through p38 MAPK and NF-κB pathways. Journal of Neuroscience Research 84:5, pages 1037-1046.
Crossref
H Nakano, A Nakajima, S Sakon-Komazawa, J-H Piao, X Xue & K Okumura. (2005) Reactive oxygen species mediate crosstalk between NF-κB and JNK. Cell Death & Differentiation 13:5, pages 730-737.
Crossref
Linda Strandberg Ihrlund, Emma Hernlund, Kristina Viktorsson, Theocharis Panaretakis, Gabor Barna, Kanaga Sabapathy, Stig Linder & Maria C. Shoshan. (2006) Two distinct steps of Bak regulation during apoptotic stress signaling: Different roles of MEKK1 and JNK1. Experimental Cell Research 312:9, pages 1581-1589.
Crossref
Brooke Helfer, Bernard C. Boswell, Darren Finlay, Angel Cipres, Kristiina Vuori, Tae Bong Kang, David Wallach, Andrea Dorfleutner, Jill M. Lahti, Daniel C. Flynn & Steven M. Frisch. (2006) Caspase-8 Promotes Cell Motility and Calpain Activity under Nonapoptotic Conditions. Cancer Research 66:8, pages 4273-4278.
Crossref
Xiaoling Tang & Keqiang Ye. (2006) Pike tyrosine phosphorylation regulates its apoptotic cleavage during programmed cell death. Advances in Enzyme Regulation 46:1, pages 289-300.
Crossref
Paul Dent, Adly Yacoub, Michael P. Hagan & Steven Grant. 2006. Cancer Drug Resistance. Cancer Drug Resistance 507 529 .
Harald Wajant. 2006. Fas Signaling. Fas Signaling 69 96 .
Dongxu Cao, Bin Qiao, Zhiqiang Ge & Yingjin Yuan. (2005) Amplification loop cascade for increasing caspase activity induced by docetaxel. Journal of Cellular Biochemistry 96:4, pages 810-820.
Crossref
Pasan Fernando, Steve Brunette & Lynn A. Megeney. (2005) Neural stem cell differentiation is dependent upon endogenous caspase‐3 activity. The FASEB Journal 19:12, pages 1671-1673.
Crossref
Francisco J. Mendoza, Elizabeth S. Henson & Spencer B. Gibson. (2005) MEKK1-induced apoptosis is mediated by Smac/Diablo release from the mitochondria. Biochemical and Biophysical Research Communications 331:4, pages 1089-1098.
Crossref
Lee J. Martin, Zhiping Liu, Juan Troncoso & Donald L. Price. 2010. Apoptosis in Health and Disease. Apoptosis in Health and Disease 96 155 .
Paul Dent. 2005. Signaling Pathways in Liver Diseases. Signaling Pathways in Liver Diseases 223 238 .
Kanghyun Ryoo, Sung-Ho Huh, Yong Hee Lee, Kyoung Wan Yoon, Ssang-Goo Cho & Eui-Ju Choi. (2004) Negative Regulation of MEKK1-induced Signaling by Glutathione S-Transferase Mu. Journal of Biological Chemistry 279:42, pages 43589-43594.
Crossref
Janet V. CROSSDennis J. TEMPLETON. (2004) Oxidative stress inhibits MEKK1 by site-specific glutathionylation in the ATP-binding domain. Biochemical Journal 381:3, pages 675-683.
Crossref
. 2004. Encyclopedic Dictionary of Genetics, Genomics and Proteomics. Encyclopedic Dictionary of Genetics, Genomics and Proteomics.
Bert Schutte, Mieke Henfling, Wendy Kölgen, Maartje Bouman, Stephan Meex, Mathie P.G Leers, Marius Nap, Viveka Björklund, Peter Björklund, Bertil Björklund, E.Birgitte Lane, M.Bishr Omary, Hans Jörnvall & Frans C.S Ramaekers. (2004) Keratin 8/18 breakdown and reorganization during apoptosis. Experimental Cell Research 297:1, pages 11-26.
Crossref
William F. Holmes, Dianne Robert Soprano & Kenneth J. Soprano. (2004) Synthetic retinoids as inducers of apoptosis in ovarian carcinoma cell lines. Journal of Cellular Physiology 199:3, pages 317-329.
Crossref
Toshiaki YUJIRI. (2004) Role of MEK kinase 1 (MEKK1) Defined by Targeted Gene Disruption. Yamaguchi Medical Journal 53:4/5, pages 215-219.
Crossref
Keiko Sato, Takahiro Taniguchi, Maiko Suzuki, Fumiaki Shinohara, Haruhiko Takada & Hidemi Rikiishi. (2004) Dual role of NF-κB in apoptosis of THP-1 cells during treatment with etoposide and lipopolysaccharide. Leukemia Research 28:1, pages 63-69.
Crossref
Iveta Dobreva, Gérard Waeber, Vincent Mooser, Richard W. James & Christian Widmann. (2003) LDLs induce fibroblast spreading independently of the LDL receptor via activation of the p38 MAPK pathway. Journal of Lipid Research 44:12, pages 2382-2390.
Crossref
Alexei Degterev, Michael Boyce & Junying Yuan. (2003) A decade of caspases. Oncogene 22:53, pages 8543-8567.
Crossref
Sun-Ryung LeeEng H. Lo. (2003) Interactions Between p38 Mitogen-Activated Protein Kinase and Caspase-3 in Cerebral Endothelial Cell Death After Hypoxia-Reoxygenation. Stroke 34:11, pages 2704-2709.
Crossref
Min Zhou, Yahong Zhang, Jeanette A. Ardans & Larry M. Wahl. (2003) Interferon-γ Differentially Regulates Monocyte Matrix Metalloproteinase-1 and -9 through Tumor Necrosis Factor-α and Caspase 8. Journal of Biological Chemistry 278:46, pages 45406-45413.
Crossref
Ryouhei Nawata, Toshiaki Yujiri, Yukinori Nakamura, Koichi Ariyoshi, Toru Takahashi, Yutaka Sato, Yoshitomo Oka & Yukio Tanizawa. (2003) MEK kinase 1 mediates the antiapoptotic effect of the Bcr-Abl oncogene through NF-κB activation. Oncogene 22:49, pages 7774-7780.
Crossref
G.L. Russo & M. Russo. (2003) Ins and outs of apoptosis in cardiovascular diseases. Nutrition, Metabolism and Cardiovascular Diseases 13:5, pages 291-300.
Crossref
Paul Dent, Adly Yacoub, Paul B Fisher, Michael P Hagan & Steven Grant. (2003) MAPK pathways in radiation responses. Oncogene 22:37, pages 5885-5896.
Crossref
Atsushi Enomoto, Norio Suzuki, Akinori Morita, Michihiko Ito, Chang Qing Liu, Yoshihisa Matsumoto, Katsuji Yoshioka, Tadayoshi Shiba & Yoshio Hosoi. (2003) Caspase-mediated cleavage of JNK during stress-induced apoptosis. Biochemical and Biophysical Research Communications 306:4, pages 837-842.
Crossref
Stephen R Plymate, Kathy H Haugk, Cynthia C Sprenger, Peter S Nelson, Marie K Tennant, Yuping Zhang, Larry W Oberley, Weixiong Zhong, Rolf Drivdahl & Terry D Oberley. (2003) Increased manganese superoxide dismutase (SOD-2) is part of the mechanism for prostate tumor suppression by Mac25/insulin-like growth factor binding-protein-related protein-1. Oncogene 22:7, pages 1024-1034.
Crossref
Harald Wajant, Klaus Pfizenmaier & Peter Scheurich. (2003) Non-apoptotic Fas signaling. Cytokine & Growth Factor Reviews 14:1, pages 53-66.
Crossref
James A. Witowsky & Gary L. Johnson. (2003) Ubiquitylation of MEKK1 Inhibits Its Phosphorylation of MKK1 and MKK4 and Activation of the ERK1/2 and JNK Pathways. Journal of Biological Chemistry 278:3, pages 1403-1406.
Crossref
U Fischer, R U Jänicke & K Schulze-Osthoff. (2003) Many cuts to ruin: a comprehensive update of caspase substrates. Cell Death & Differentiation 10:1, pages 76-100.
Crossref
Tracie A. DeVries, Margaret C. Neville & Mary E. Reyland. (2002) Nuclear import of PKCδ is required for apoptosis: identification of a novel nuclear import sequence. The EMBO Journal 21:22, pages 6050-6060.
Crossref
Pamela Cameron, Deborah Bingham, Andrew Paul, Martin Pavelka, Scott Cameron, Dino Rotondo & Robin Plevin. (2002) Essential Role for Verotoxin in Sustained Stress-Activated Protein Kinase and Nuclear Factor Kappa B Signaling, Stimulated by Escherichia coli O157:H7 in Vero Cells . Infection and Immunity 70:10, pages 5370-5380.
Crossref
Andrea H Bild, Francisco J Mendoza, Erika M Gibson, Mei Huang, Jacylyn Villanueva, Timothy P Garrington, Richard Jove, Gary L Johnson & Spencer B Gibson. (2002) MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage. Oncogene 21:43, pages 6649-6656.
Crossref
B Ye, N Sugo, P.D Hurn & R.L Huganir. (2002) Physiological and pathological caspase cleavage of the neuronal RasGEF GRASP-1 as detected using a cleavage site-specific antibody. Neuroscience 114:1, pages 217-227.
Crossref
Pasan Fernando, John F. Kelly, Kim Balazsi, Ruth S. Slack & Lynn A. Megeney. (2002) Caspase 3 activity is required for skeletal muscle differentiation. Proceedings of the National Academy of Sciences 99:17, pages 11025-11030.
Crossref
Christian LesuisseLee J. Martin. (2016) Immature and Mature Cortical Neurons Engage Different Apoptotic Mechanisms Involving Caspase-3 and the Mitogen-Activated Protein Kinase Pathway. Journal of Cerebral Blood Flow & Metabolism 22:8, pages 935-950.
Crossref
Hailing Jin, Michael J. Axtell, Douglas Dahlbeck, Obi Ekwenna, Shuqun Zhang, Brian Staskawicz & Barbara Baker. (2002) NPK1, an MEKK1-like Mitogen-Activated Protein Kinase Kinase Kinase, Regulates Innate Immunity and Development in Plants. Developmental Cell 3:2, pages 291-297.
Crossref
Alessandra M. A. Di Bacco & Thomas G. Cotter. (2002) p53 expression in K562 cells is associated with caspase-mediated cleavage of c-ABL and BCR-ABL protein kinases. British Journal of Haematology 117:3, pages 588-597.
Crossref
David J. MacEwan. (2002) TNF receptor subtype signalling: Differences and cellular consequences. Cellular Signalling 14:6, pages 477-492.
Crossref
Jiang-Yan Yang & Christian Widmann. (2002) The RasGAP N-terminal Fragment Generated by Caspase Cleavage Protects Cells in a Ras/PI3K/Akt-dependent Manner That Does Not Rely on NFκB Activation. Journal of Biological Chemistry 277:17, pages 14641-14646.
Crossref
Erika M. Gibson, Elizabeth S. Henson, Jacylyn Villanueva & Spencer B. Gibson. (2002) MEK Kinase 1 Induces Mitochondrial Permeability Transition Leading to Apoptosis Independent of Cytochrome cRelease. Journal of Biological Chemistry 277:12, pages 10573-10580.
Crossref
Thomas K. Schlesinger, Christelle Bonvin, Matthew B. Jarpe, Gary R. Fanger, Jean-René Cardinaux, Gary L. Johnson & Christian Widmann. (2002) Apoptosis Stimulated by the 91-kDa Caspase Cleavage MEKK1 Fragment Requires Translocation to Soluble Cellular Compartments. Journal of Biological Chemistry 277:12, pages 10283-10291.
Crossref
Christelle Bonvin, Audrey Guillon, Miguel X van Bemmelen, Pär Gerwins, Gary L Johnson & Christian Widmann. (2002) Role of the amino-terminal domains of MEKKs in the activation of NFκB and MAPK pathways and in the regulation of cell proliferation and apoptosis. Cellular Signalling 14:2, pages 123-131.
Crossref
Maria Alvarado-Kristensson, M. Isabella Pörn-Ares, Simone Grethe, David Smith, Limin Zheng & Tommy Andersson. (2001) p38 Mitogen‐activated protein kinase and phosphatidylinositol 3‐kinase activities have opposite effects on human neutrophil apoptosis. The FASEB Journal 16:1, pages 1-22.
Crossref
Carsten Hagemann & Jonathan L. Blank. (2001) The ups and downs of MEK kinase interactions. Cellular Signalling 13:12, pages 863-875.
Crossref
Shane C. Masters & Haian Fu. (2001) 14-3-3 Proteins Mediate an Essential Anti-apoptotic Signal. Journal of Biological Chemistry 276:48, pages 45193-45200.
Crossref
Yanping Hu, Wieslawa H. Dragowska, Anne Wallis, Vincent Duronio & Lawrence Mayer. (2001) Cytotoxicity induced by manipulation of signal transduction pathways is associated with down-regulation of Bcl-2 but not Mcl-1 in MCF-7 human breast cancer. Breast Cancer Research and Treatment 70:1, pages 11-20.
Crossref
Victoria Drewett, Andrew Devitt, Janice Saxton, Neil Portman, Peter Greaney, NaEun Cheong, Teresa F. Alnemri, Emad Alnemri & Peter E. Shaw. (2001) Serum Response Factor Cleavage by Caspases 3 and 7 Linked to Apoptosis in Human BJAB Cells. Journal of Biological Chemistry 276:36, pages 33444-33451.
Crossref
Seiji Ura, Norihisa Masuyama, Jonathan D. Graves & Yukiko Gotoh. (2001) Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation. Proceedings of the National Academy of Sciences 98:18, pages 10148-10153.
Crossref
Hayley M. McDaid & Susan Band Horwitz. (2001) Selective Potentiation of Paclitaxel (Taxol)-Induced Cell Death by Mitogen-Activated Protein Kinase Kinase Inhibition in Human Cancer Cell Lines. Molecular Pharmacology 60:2, pages 290-301.
Crossref
Olga Potapova, Subarna Basu, Dan Mercola & Nikki J. Holbrook. (2001) Protective Role for c-Jun in the Cellular Response to DNA Damage. Journal of Biological Chemistry 276:30, pages 28546-28553.
Crossref
Terence F. McGuire, Donald L. Trump & Candace S. Johnson. (2001) Vitamin D3-induced Apoptosis of Murine Squamous Cell Carcinoma Cells. Journal of Biological Chemistry 276:28, pages 26365-26373.
Crossref
Jin Woo Kim, Cheol O. Joe & Eui-Ju Choi. (2001) Role of Receptor-interacting Protein in Tumor Necrosis Factor-α-dependent MEKK1 Activation. Journal of Biological Chemistry 276:29, pages 27064-27070.
Crossref
Shenaz Khan, Alexandra Koepke, George Jarad, Katie Schlessman, Ronald P. Cleveland, Bingcheng Wang, Martha Konieczkowski & Jeffrey R. Schelling. (2001) Apoptosis and JNK activation are differentially regulated by Fas expression level in renal tubular epithelial cells. Kidney International 60:1, pages 65-76.
Crossref
Hironori Nakagami, Ryuichi Morishita, Kei Yamamoto, Shin-ichi Yoshimura, Yoshiaki Taniyama, Motokuni Aoki, Hiroaki Matsubara, Shokei Kim, Yasufumi Kaneda & Toshio Ogihara. (2001) Phosphorylation of p38 Mitogen-Activated Protein Kinase Downstream of Bax-Caspase-3 Pathway Leads to Cell Death Induced by High d -Glucose in Human Endothelial Cells . Diabetes 50:6, pages 1472-1481.
Crossref
Cheh Peng Lim & Xinmin Cao. (2001) Regulation of Stat3 Activation by MEK Kinase 1. Journal of Biological Chemistry 276:24, pages 21004-21011.
Crossref
Sandrine Willaime, Peter Vanhoutte, Jocelyne Caboche, Yolande Lemaigre-Dubreuil, Jean Mariani & Bernard Brugg. (2001) Ceramide-induced apoptosis in cortical neurons is mediated by an increase in p38 phosphorylation and not by the decrease in ERK phosphorylation. European Journal of Neuroscience 13:11, pages 2037-2046.
Crossref
Anatoli B. Meriin, Katsuhide Mabuchi, Vladimir L. Gabai, Julia A. Yaglom, Alex Kazantsev & Michael Y. Sherman. (2001) Intracellular Aggregation of Polypeptides with Expanded Polyglutamine Domain Is Stimulated by Stress-Activated Kinase Mekk1. The Journal of Cell Biology 153:4, pages 851-864.
Crossref
Raymond H. See, Dominica Calvo, Yujiang Shi, Hidehiko Kawa, Margaret Po-Shan Luke, Zhimin Yuan & Yang Shi. (2001) Stimulation of p300-mediated Transcription by the Kinase MEKK1. Journal of Biological Chemistry 276:19, pages 16310-16317.
Crossref
Ippeita Dan, Norinobu M. Watanabe & Akihiro Kusumi. (2001) The Ste20 group kinases as regulators of MAP kinase cascades. Trends in Cell Biology 11:5, pages 220-230.
Crossref
Jürgen Hoppe, Viviane Hoppe & Rolf Schäfer. (2001) Selective Degradation of the PKC-ϵ Isoform during Cell Death in AKR-2B Fibroblasts. Experimental Cell Research 266:1, pages 64-73.
Crossref
John M. Kyriakis & Joseph Avruch. (2001) Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation. Physiological Reviews 81:2, pages 807-869.
Crossref
Dipshikha Chakravortty, Yutaka Kato, Tsuyoshi Sugiyama, Naoki Koide, Mya Mya Mu, Tomoaki Yoshida & Takashi Yokochi. (2001) Inhibition of Caspase 3 Abrogates Lipopolysaccharide-Induced Nitric Oxide Production by Preventing Activation of NF-κB and c-Jun NH 2 -Terminal Kinase/Stress-Activated Protein Kinase in RAW 264.7 Murine Macrophage Cells . Infection and Immunity 69:3, pages 1315-1321.
Crossref
Veronika JesenbergerKatarzyna J. ProcykJochen RüthMartin SchreiberHans-Christian Theussl, Erwin F. Wagner & Manuela Baccarini. (2001) Protective Role of Raf-1 in Salmonella-Induced Macrophage Apoptosis. Journal of Experimental Medicine 193:3, pages 353-364.
Crossref
Shine-Gwo Shiah, Shuang-En Chuang & Min-Liang Kuo. (2001) Involvement of Asp-Glu-Val-Asp-Directed, Caspase-Mediated Mitogen-Activated Protein Kinase Kinase 1 Cleavage, c-Jun N-Terminal Kinase Activation, and Subsequent Bcl-2 Phosphorylation for Paclitaxel-Induced Apoptosis in HL-60 Cells. Molecular Pharmacology 59:2, pages 254-262.
Crossref
Marc J. Servant, Benjamin ten Oever, Cecile LePage, Lucia Conti, Sandra Gessani, Ilkka Julkunen, Rongtuan Lin & John Hiscott. (2001) Identification of Distinct Signaling Pathways Leading to the Phosphorylation of Interferon Regulatory Factor 3. Journal of Biological Chemistry 276:1, pages 355-363.
Crossref
Yutaka Masuda, Mie Nakaya, Toshihiro Aiuchi, Sachiko Hashimoto, Shigeo Nakajo & Kazuyasu Nakaya. (2000) The mechanism of geranylgeraniol-induced apoptosis involves activation, by a caspase-3-like protease, of a c-Jun N-terminal kinase signaling cascade and differs from mechanisms of apoptosis induced by conventional chemotherapeutic drugs. Leukemia Research 24:11, pages 937-950.
Crossref
Jingping Wang & Eileen Friedman. (2000) Downregulation of p53 by sustained JNK activation during apoptosis. Molecular Carcinogenesis 29:3, pages 179-188.
Crossref
Sébastien S. Hébert, Alex Daviau, Gilles Grondin, Mathieu Latreille, Rémy A. Aubin & Richard Blouin. (2000) The Mixed Lineage Kinase DLK Is Oligomerized by Tissue Transglutaminase during Apoptosis. Journal of Biological Chemistry 275:42, pages 32482-32490.
Crossref
Viktor Lakics, Andrei E. Medvedev, Seiji Okada & Stefanie N. Vogel. (2000) Inhibition of LPS-induced Cytokines by Bcl-xL in a Murine Macrophage Cell Line. The Journal of Immunology 165:5, pages 2729-2737.
Crossref
Robert V. Talanian, Kenneth D. Brady & Vincent L. Cryns. (2000) Caspases as Targets for Anti-Inflammatory and Anti-Apoptotic Drug Discovery. Journal of Medicinal Chemistry 43:18, pages 3351-3371.
Crossref
Benjamin D. Humphreys, Janet Rice, Sylvia B. Kertesy & George R. Dubyak. (2000) Stress-activated Protein Kinase/JNK Activation and Apoptotic Induction by the Macrophage P2X7 Nucleotide Receptor. Journal of Biological Chemistry 275:35, pages 26792-26798.
Crossref
P J Utz & P Anderson. (2000) Life and death decisions: regulation of apoptosis by proteolysis of signaling molecules. Cell Death & Differentiation 7:7, pages 589-602.
Crossref
Juan A. Osés-Prieto, Natalia López-Moratalla, Esteban Santiago, Jean P. Jaffrézou & Maria J. López-Zabalza. (2000) Molecular Mechanisms of Apoptosis Induced by an Immunomodulating Peptide on Human Monocytes. Archives of Biochemistry and Biophysics 379:2, pages 353-362.
Crossref
Taeil Kim, Tae Young Kim, Woo Ghil Lee, Jeongbin Yim & Tae Kook Kim. (2000) Signaling Pathways to the Assembly of an Interferon-β Enhanceosome. Journal of Biological Chemistry 275:22, pages 16910-16917.
Crossref
Frank van Drogen, Sean M. O’Rourke, Volker M. Stucke, Malika Jaquenoud, Aaron M. Neiman & Matthias Peter. (2000) Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signaling in vivo. Current Biology 10:11, pages 630-639.
Crossref
Bing Ye, Dezhi Liao, Xiaoqun Zhang, Peisu Zhang, Hualing Dong & Richard L Huganir. (2000) GRASP-1. Neuron 26:3, pages 603-617.
Crossref
Edwin G Krebs & Jonathan D Graves. (2000) Interactions between protein kinases and proteases in cellular signaling and regulation. Advances in Enzyme Regulation 40:1, pages 441-470.
Crossref
Filomena de Nigris, Flavia Franconi, Ivana Maida, Giuseppe Palumbo, Vittorio Anania & Claudio Napoli. (2000) Modulation by α- and γ-tocopherol and oxidized low-density lipoprotein of apoptotic signaling in human coronary smooth muscle cells∗. Biochemical Pharmacology 59:11, pages 1477-1487.
Crossref
Zhiwu Lin, Joel M. Weinberg, Ricky Malhotra, Steven E. Merritt, Lawrence B. Holzman & Frank C. BrosiusIIIIII. (2000) GLUT-1 reduces hypoxia-induced apoptosis and JNK pathway activation. American Journal of Physiology-Endocrinology and Metabolism 278:5, pages E958-E966.
Crossref
David S. Cassarino, Erik M. Halvorsen, Russell H. Swerdlow, Nicole N. Abramova, W. Davis ParkerJr.Jr., Thomas W. Sturgill & James P. BennettJr.Jr.. (2002) Interaction Among Mitochondria, Mitogen-Activated Protein Kinases, and Nuclear Factor-κB in Cellular Models of Parkinson's Disease. Journal of Neurochemistry 74:4, pages 1384-1392.
Crossref
Gérard Waeber, Jérôme Delplanque, Christophe Bonny, Vincent Mooser, Myriam Steinmann, Christian Widmann, Anne Maillard, Judith Miklossy, Christian Dina, El H Hani, Gérard Waeber, Jérôme Delplanque, Nathalie Vionnet, Pascal Nicod, Philippe Boutin & Philippe Froguel. (2000) The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes. Nature Genetics 24:3, pages 291-295.
Crossref
L. Michea, D. R. Ferguson, E. M. Peters, P. M. Andrews, M. R. Kirby & M. B. Burg. (2000) Cell cycle delay and apoptosis are induced by high salt and urea in renal medullary cells. American Journal of Physiology-Renal Physiology 278:2, pages F209-F218.
Crossref
Sheau Yu Hsu & Aaron J. W. Hsueh. (2000) Tissue-Specific Bcl-2 Protein Partners in Apoptosis: An Ovarian Paradigm. Physiological Reviews 80:2, pages 593-614.
Crossref
Puddicombe & Davies. (2000) The role of MAP kinases in intracellular signal transduction in bronchial epithelium. Clinical & Experimental Allergy 30:1, pages 7-11.
Crossref
Ryuichi Nishihama & Yasunori Machida. 2000. MAP Kinases in Plant Signal Transduction. MAP Kinases in Plant Signal Transduction 119 130 .
Sabine Häussermann, Walter Kittstein, Gabriele Rincke, Franz-Josef Johannes, Friedrich Marks & Michael Gschwendt. (1999) Proteolytic cleavage of protein kinase Cμ upon induction of apoptosis in U937 cells. FEBS Letters 462:3, pages 442-446.
Crossref
Yi-Rong Chen, Christian F Meyer, Bushra Ahmed, Zhengbin Yao & Tse-Hua Tan. (1999) Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1). Oncogene 18:51, pages 7370-7377.
Crossref
Xiao Hua Li, Kathleen M. Murphy, Kevin T. Palka, Rama Mohan Surabhi & Richard B. Gaynor. (1999) The Human T-cell Leukemia Virus Type-1 Tax Protein Regulates the Activity of the IκB Kinase Complex. Journal of Biological Chemistry 274:48, pages 34417-34424.
Crossref
Klaus P Hoeflich, Wen-Chen Yeh, Zhengbin Yao, Tak W Mak & James R Woodgett. (1999) Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1). Oncogene 18:42, pages 5814-5820.
Crossref
Wen-Hui Hu, Holly Johnson & Hong-Bing Shu. (1999) Tumor Necrosis Factor-related Apoptosis-inducing Ligand Receptors Signal NF-κB and JNK Activation and Apoptosis through Distinct Pathways. Journal of Biological Chemistry 274:43, pages 30603-30610.
Crossref
Alan G. Porter. (1999) Protein translocation in apoptosis. Trends in Cell Biology 9:10, pages 394-401.
Crossref
Sic L. Chan & Mark P. Mattson. (1999) Caspase and calpain substrates: Roles in synaptic plasticity and cell death. Journal of Neuroscience Research 58:1, pages 167-190.
Crossref
Helena Larsson, Peter Klint, Eva Landgren & Lena Claesson-Welsh. (1999) Fibroblast Growth Factor Receptor-1-mediated Endothelial Cell Proliferation Is Dependent on the Src Homology (SH) 2/SH3 Domain-containing Adaptor Protein Crk. Journal of Biological Chemistry 274:36, pages 25726-25734.
Crossref
Neville Marks & Martin J. Berg. (1999) Recent advances on neuronal caspases in development and neurodegeneration. Neurochemistry International 35:3, pages 195-220.
Crossref
Steffen P. Hehner, Thomas G. Hofmann, Frank Ratter, Wulf Droge & M. Lienhard Schmitz. (1999) Inhibition of tyrosine phosphatases antagonizes CD95-mediated apoptosis. European Journal of Biochemistry 264:1, pages 132-139.
Crossref
Julie Y. Reuther & Albert S. BaldwinJr.Jr.. (1999) Apoptosis Promotes a Caspase-induced Amino-terminal Truncation of IκBα That Functions as a Stable Inhibitor of NF-κB. Journal of Biological Chemistry 274:29, pages 20664-20670.
Crossref
Mary E. Reyland, Steven M. Anderson, Angela A. Matassa, Kathy A. Barzen & David O. Quissell. (1999) Protein Kinase C δ Is Essential for Etoposide-induced Apoptosis in Salivary Gland Acinar Cells. Journal of Biological Chemistry 274:27, pages 19115-19123.
Crossref
Isabel Sánchez-Pérez & Rosario Perona. (1999) Lack of c-Jun activity increases survival to cisplatin. FEBS Letters 453:1-2, pages 151-158.
Crossref
Taro Kawai, Fumiko Nomura, Katsuaki Hoshino, Neal G Copeland, Debra J Gilbert, Nancy A Jenkins & Shizuo Akira. (1999) Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity. Oncogene 18:23, pages 3471-3480.
Crossref
William C. EarnshawLuis M. MartinsScott H. Kaufmann. (1999) Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis. Annual Review of Biochemistry 68:1, pages 383-424.
Crossref
Jeffrey C. RathmellCraig B. Thompson. (1999) THE CENTRAL EFFECTORS OF CELL DEATH IN THE IMMUNE SYSTEM. Annual Review of Immunology 17:1, pages 781-828.
Crossref
Toshiaki Yujiri, Gary R. Fanger, Timothy P. Garrington, Thomas K. Schlesinger, Spencer Gibson & Gary L. Johnson. (1999) MEK Kinase 1 (MEKK1) Transduces c-Jun NH2-terminal Kinase Activation in Response to Changes in the Microtubule Cytoskeleton. Journal of Biological Chemistry 274:18, pages 12605-12610.
Crossref
Spencer Gibson, Christian Widmann & Gary L. Johnson. (1999) Differential Involvement of MEK Kinase 1 (MEKK1) in the Induction of Apoptosis in Response to Microtubule-targeted Drugsversus DNA Damaging Agents. Journal of Biological Chemistry 274:16, pages 10916-10922.
Crossref
Sonia Frutos, Jorge Moscat & Marı́a T. Diaz-Meco. (1999) Cleavage of ζPKC but Not λ/ιPKC by Caspase-3 during UV-induced Apoptosis. Journal of Biological Chemistry 274:16, pages 10765-10770.
Crossref
Timothy P Garrington & Gary L Johnson. (1999) Organization and regulation of mitogen-activated protein kinase signaling pathways. Current Opinion in Cell Biology 11:2, pages 211-218.
Crossref
Isao Ozaki, Eiichi Tani, Hideyasu Ikemoto, Hiroyuki Kitagawa & Hirokazu Fujikawa. (1999) Activation of Stress-activated Protein Kinase/c-Jun NH2-terminal Kinase and p38 Kinase in Calphostin C-induced Apoptosis Requires Caspase-3-like Proteases but Is Dispensable for Cell Death. Journal of Biological Chemistry 274:9, pages 5310-5317.
Crossref
CHRISTIAN WIDMANN, SPENCER GIBSON, MATTHEW B. JARPE & GARY L. JOHNSON. (1999) Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human. Physiological Reviews 79:1, pages 143-180.
Crossref
Lori B. Christerson, Colleen A. Vanderbilt & Melanie H. Cobb. (1999) MEKK1 interacts with ?-actinin and localizes to stress fibers and focal adhesions. Cell Motility and the Cytoskeleton 43:3, pages 186-198.
Crossref
David K Perry & Yusuf A Hannun. (1998) The role of ceramide in cell signaling. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1436:1-2, pages 233-243.
Crossref
Yelena Kovtun, Wan-Ling Chiu, Weike Zeng & Jen Sheen. (1998) Suppression of auxin signal transduction by a MAPK cascade in higher plants. Nature 395:6703, pages 716-720.
Crossref
Renee L Rice, Dean G Tang & John D Taylor. (1998) Actin cleavage in various tumor cells is not a critical requirement for executing apoptosis. Pathology & Oncology Research 4:2, pages 135-145.
Crossref

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